Toll-like receptor 4 signalling

This movie details how lipopolysaccharide (LPS) from Gram-negative bacteria binds to Toll-like receptor 4 to initiate cell signaling.

[@BillysCards]

I'm shocked this video has less than 10,000 views. One of the best instructional biology videos I have ever seen.

[@tzadokyona8128]

This is probably the best Biology video i have ever seen.

[@wthitskianna]

I just learned 2 months worth of Immunology in one video. Thank you!!!

[@paulaivanimedeirosdossanto2643]

The best video on immunology.

[@UltaGuide]

A semester of struggling already cleared up before 1:30. This needs to be seen more.

[@AreciboBand]

This video is honestly amazing, it deserves way more views that its had

[@truongtrieutien9010]

The quality of this video is so good 👏👏👏

[@mayaabdalhadi3880]

Honestly, one of the best animations I’ve ever seen. Amazing graphics that simplified this concept, Well done .

[@josemanuelnegroe9992]

this video is a masterpiece

[@danielmaringellipasqui1593]

What an amazing video! It's really sad to realize that it has much less views than it deserves, because it makes clear, in a graphic way, the beauty of our Immune System! Thank you very much for producing this kind of content!

[@AbhaySingh-wi4qu]

Great video

[@ayeshaarshad95439]

never seen such quality biology video before!

[@TransportRoutine]

Ok I just finished watching it and I am in awe!! Insane graphics and great explanation!! Bravo! (very underrated video)

[@nicolemillwood8719]

Not all heros wear capes

[@sakshiverma3190]

Very nice video

[@michellebraga9224]

Wow... breathtaking video! Super fun and enlightening

[@antoniofratini6293]

Amazing video. Thank you.

[@Sara-ex5qb]

Thank you so much for this simple yet informative explanation.

[@karlazamora4327]

Excellent video, thanks!

[@catescsc]

Wow. Fantastic video! I was looking for an elaboration on TLRs for a college major’s biology class, and this exceeded anything else I found. Thank you!!

[@MrMardalock]

This is the best video about tlr4 I've found on the internet,great job !

[@insiyafathimamoosavi8186]

This is such a well-made video! Great job!

[@rafaelcalderon3681]

Mano, este vídeo parece una documental. Esta bien duro

[@henrysanchez1779]

Wow! Great video. Really useful, thank you so much

[@SamIdiot]

this is the best video I've ever seen.!!! it's amazing. Thank you so much :D

[@darkblue1423]

Wow! very well done, just did the job of God knows how many hours of reading text and not getting anything out of it in just 5 minute which is ACTUALLY useful and not making me more confused in compare to other vidz out there!!! Thank you so much, Keep up the great job and PLEASE make more of such informative precise videos ;-)

[@rahafaltaher4553]

That's fact the video is very good , but i was have question about your god? You are christians or muslim?! I wanna ask after all this hermonize structure and pathway How the non-muslim not search and find the truth . Allah said in his book (holy Qura'n): We will show them Our signs on the horizons, and within themselves-until it becomes clear to them that it is the truth. Is it not enough that your Lord is a witness over everything? Surah Fussilat 53. I hope you are muslim . Or search about the fact

[@darkblue1423]

Hello brother, I'm muslim and that was just a typo, "of" was extra there. I know it well better than you and as also God himself said in Quran, Do not be nosy about the things that are not your business, refer you to that ayah, wish you well and hope you learn the scientific aspect of this video rather than reading other's comments and try to preach under a scientific topic. peace@@rahafaltaher4553

[@Miniclipzx]

This is very clear and fun!

[@SarahMMorsy]

this is amazing, thank you for this experience

[@hmh6040]

What a great video! It's very clear and helpful, thank you!

[@shankhamitrapaul6370]

What a work!!It's more than amazing🙂🙂 and helped me a lot....

[@alexandersupertramp151]

Absolutely fantastic.. please make more of these.. Cheers.. :)

[@mafaldapinho9523]

This is amazing! Thank you so much!

[@SpartanTutorials]

Beautiful animation! Thanks for sharing!

[@nestdalebartolome8335]

Well delivered

[@musabzulfiqar]

Really well done video man

[@julianajesusdonascimento875]

Congratulations , it is amazing video. Thank you

[@karenbeard7040]

Amazing video!!! Thank you for sharing it :)

[@TheBeastNme]

Nice work.

[@Zitysek]

Really helpful! Thank you!

[@alisadek3411]

excellent work...

[@katherinelindstrom6109]

Wonderful! Thank you!

[@christiancastro978]

Wow!!, Great work !!

[@sheebajobanputra4729]

Fantastic

[@joshuasorenson5162]

That was great! Thank you!

[@mako5500]

It's just amazing! Thank you! Hope you can load more :)

[@mroosie7488]

Super video!

[@immadisarojini2775]

Super

[@annewilson6096]

Thank you!

[@cathymiller3086]

excellent! thank you!

[@DrCharlesParker]

Excellent video! Loaded it on my LPS playlist for immunity ed with patients who are treatment failures. Which one of you guys recorded this? Very helpful.

[@Jana-tb8rw]

Amaaazinngggg videooo

[@MeganWhamGMfan]

bacteria: enters innate cells: huh? Who invited you guys your not on the list!? adaptive cells: let me deal with these dick heads

[@abdal-rahmansalous6032]

Perfect👏

[@laceywhite2656]

Please give some insight on any knowledge you have on how taxol damages the TLR4 pathway - cipn symptoms are HORRIBLE and doctors advise irreversible- quality of life is too poor. I am on a desperate search.

[@momofromatla2318]

My teacher(med school) put this video’s link on her ppt.

[@HimanshuSharma-oy9ss]

came here after searching for CD14, only to be awestructed.

[@madjedatarek9355]

Wow wow wow

[@rachellewis9791]

Do all cells contain TLR4?

[@jhannelsmith7619]

Omg the best

[@rommelalberan5508]

Why you put these gloomy and ominous background music in an educational video???

[@tessacarstairs5998]

proud for my school :D

[@dogah1620]

the video is beautiful but it could contain more information :( not enough for med school

[@subinbyclema]

Innate immune system mucosal chemical barrier skin PRR nonself molecule pamps TLR 10 members family LPS TLR4 LPS gram - Bacteria CD14 soluble MD-2 ecto domains TIR domain adapter protein Myd88 NFkB TF inhibitor lkB phopsphorylating IkB innate immnue response inflammatory response

[@rahafaltaher4553]

I wanna ask after all this hermonize structure and pathway how can the one become disbelivers in existence of god, and he just simply beleive in darwin theory and that we come from explosion or by mistake?! How the non-muslim not search and find the truth . Allah said in his book (holy Qura'n): We will show them Our signs on the horizons, and within themselves-until it becomes clear to them that it is the truth. Is it not enough that your Lord is a witness over everything? Surah Fussilat 53.