Pattern Recognition Receptors

We've already introduced pattern-recognition receptors, which recognize PAMPs and DAMPs, but now let's go over the specific types, and how they work. How many Toll-like receptors are there and what do they recognize? What are the adaptor proteins that kick off their signal transduction pathways? What about NOD-like receptors and RIG-I-like helicases? So much to discuss!
Script by Stephanie Melchor
Select images provided by BioRender.com
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[@fazergazer]

I’ve worked on TLR family proteins in my research. This is an accurate and concise introduction, I hope as many researchers watch it. Isn’t this system beautiful? Thanks!

[@anwaraltamimi3592]

It is!!!

[@user-vu9st6fd7v]

Awesome!!

[@RobertoCighetti]

I did my thesis and my PhD on TLR4! 😍 Really loved this video, concise but very informative

[@indiabiologyexplains5013]

This video was probably one of the most useful lessons on biology I have ever had. Thanks for teacher thousands of more like me and continue what your doing!

[@yes7855]

Beautiful and completely kept my attention the whole way! Thanks for being a blessing, lovely team ❤️❤️❤️

[@abeerabu-eisheh5395]

OMG How smooth you explain every single point!!👏🏻👏🏻 You are so talented 👌🏻

[@santicruz4012]

The amount of content you put up is incredi le

[@evelin5255]

thank you for helping me with my bachelors thesis in immunology :')

[@mahinvasavada2992]

Clear, simple, perfect.

[@user-margaritasourri]

My master's thesis is on TLRs, thank you for this video, it is very informative!

[@user-vu9st6fd7v]

U r truly AMAZING Prof. Dave❤️‍🔥

[@alashikbillah4096]

You are a saviour to the medical students like me 🙏

[@sciencenerd7639]

It seems to me that bacterial flagella are more corkscrew-like than whip like. That is, bacterial flagella spiral while eukaryotic flagella whip (if I remember right). In any case, this is an amazing, fantastic video, and I tremendously appreciate your work!

[@-JA-]

Thank you.

[@sciencenerd7639]

thank you

[@michaeldob2153]

great vid! My question is since DAMP's are associated with Cell damage. Is a local limited hyperkalema kind of DAMP too?

[@imtiredofitallmakeitstop]

thanks dave

[@SCIPROlearning]

Great 👍👍👍

[@NovaWarrior77]

bless you bro

[@davidsweeney111]

Interesting theory

[@mohamhashem331]

thank you sir you rescued me

[@samirdileep]

What about TLR-8? What does it bind to?

[@sauhardshrivastava7456]

Just one issue, MDA5 senses dsRNA and not dsDNA... Other than that it's perfect

[@blocksbrains4911]

I love listening to this rich knowledge in comparison to the flat earth vids. You are a good man.

[@vimpirani1680]

Tell me about antimatter

[@probabiltywave7582]

I have a hypothetical question not related to this video. Assume we have a small pressurized container that holds the same amount of air atmosphere on planet earth. If we open this container on earth till empty what will happen to earth air pressure ? Will the atmospheric pressure double or will remain the same and the extra air will escape earth gravity ? Don't know how to handle this hypothetical problem. Hope you could guide me.

[@probabiltywave7582]

@Wh•a•t•sap÷❶❷❸❹❷❸❶❹❶❸❻ where can I find him ? Sorry not familiar with the name.

[@ArveEriksson]

Gee whiz, I learn stuff about my job by going to KZbin U. What a society we live in! Completely unrelated tangent: In Sweden, some decade(s?) ago 'damp' was used as some type of slur against people with ADHD. I have bugger-all idea why. (On a side-note: I get ads from ThermoScientific on this video, and I love it.)

[@fusionhypnotic]

blows my mind how complex we are

[@bhaktithakur2185]

Can extracellular ss rna indicate damage to tissue cells ?

[@indiabiologyexplains5013]

They could. But some RNA is used in cell to cell communication.

[@bigbeans202]

Hiya Dave, love the vids. Would love to see some computer science videos!

[@ProfessorDaveExplains]

I'll get to that eventually! I want to do all kinds of engineering, including electrical engineering first, so that I there is no gap when discussing computer components.

[@masternobody1896]

@@ProfessorDaveExplains can you make more video about immune system

[@masternobody1896]

@@ProfessorDaveExplains why does cancer form and how to destroy cancer?

[@ProfessorDaveExplains]

This is a whole immunology playlist so there will be many more. As for cancer, start with my biochemistry tutorial "what is cancer".

[@bigbeans202]

Awesome! So glad you'll get to that. I'm currently doing my Major in CS :)

[@Carlosk12]

Sees an oval inside any figure Me: AMOGUS PATTERN RECOGNITION

[@sadbois4546]

I would love merch lol idk why. 😂

[@ProfessorDaveExplains]

Check out my store tab!

[@sadbois4546]

@@ProfessorDaveExplains Thanks!!!

[@whatsagoodusername823]

Unul pentru algoritm

[@anandkishor2791]

Hyyy

[@HarryTheLoser_]

:)

[@1.4142]

RAGE

[@Nesteate]

What if the reason he knows so much is, HE IS JESUS

[@nurphurecarnium]

Ironic since he is an atheist 🙃

[@IsaacAwad.04]

Why do u stopped showing your self talk in the video ? Like I dont mind but you did that for so long. haha ok bye thx.😊

[@ProfessorDaveExplains]

I don't have access to KZbin studios anymore, where I used to shoot my content, so I can't do what I used to do with a nice camera and green screen. So I do audio only, except for my debunks where I use my webcam.

[@IsaacAwad.04]

@@ProfessorDaveExplains np I still understand everything you teatcher thx dave 😁

[@ju_2076]

The earth is flat