Trimethylamine N-oxide (TMAO)

What is TMAO? And why should you care?
Well, TMAO is Trimethylamine N-oxide. Essentially, it's a pro-atherogenic metabolite, which means that it basically causes plaque to build up inside your vessels.
What's the main source? Turns out its meat.
It's actually made by eating animal products containing choline, containing L-carnitine, or containing phosphatidylcholine.
And TMAO concentrations inside your blood can actually predict the severity of the heart attack that you might have.
In addition, TMAO concentrations are also linked to chronic kidney disease, heart failure, and clots.
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Sources:
Koeth et al. Nat. Med. 2013
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