What is Oligometastatic Prostate Cancer?

[@DCGreenZone]

What were the results of Clarity's Cu67 second dosing? Answer wisely.

[@roberthuff3122]

🎯 Key points for quick navigation: 00:40 *📚 Oligometastatic Cancer Concept* - Oligometastatic cancer is an intermediate state of cancer spread. - Defined by limited metastases (1-5), though biological characteristics also play a role. - Some metastatic cancer cases with limited metastases could be potentially curable. 02:07 *🔬 Evolving Definitions and Treatments* - Synchronous oligometastatic disease occurs at initial diagnosis, while metachronous occurs post-treatment. - SBRT (stereotactic body radiation therapy) is used to treat oligometastases with high precision. - Clinical trials are exploring the benefits of local radiation therapy for oligometastases. 05:25 *🩺 Impact of Hormone and Radiation Therapy* - EXTEND trial combines hormone therapy with SBRT for treating metastasis. - SBRT can extend progression-free survival without affecting quality of life. - Prostate cancer is often more responsive to oligometastatic treatment strategies. 07:16 *🧪 Advanced Imaging's Role* - PSMA PET scans improve detection of metastases, refining treatment approaches. - Complete treatment of detected lesions on PSMA PET leads to better outcomes. - Clinical trials like ORIOLE include PSMA PET to enhance treatment analysis. 08:47 *💊 Hormonal Therapy Considerations* - Combining SBRT with hormones improves outcomes but the necessity varies. - Hormonal therapy decisions depend on risk factors such as PSA levels and metastasis location. - Newer imaging technologies influence the strategy and duration of hormonal therapy. 13:01 *🗝️ Treatment Strategies and Goals* - Treatment strategies vary from minimal hormonal intervention to extensive. - The goal is curing or delaying disease progression, depending on patient preferences. - Multi-time radiation with SBRT has allowed prolonged management of prostate cancer. 16:30 *🎯 Adapting to New Discoveries* - Iterative PSA testing coupled with PSMA PET can identify precise treatment targets. - Repeated radiation cycles have shown to delay systemic therapy effectively. - This evolving approach has transformed prostate cancer management, showing promise in curative treatments. Made with HARPA AI

[@DCGreenZone]

Is there a role for mebendazole, ivermectin, Fenbendazole. Answer wisely.

[@LiberaTeTutemetExInferis]

There are some promising studies, still a long way to go.....

[@DCGreenZone]

@@LiberaTeTutemetExInferis If you read Dr. Tom Roger's comment section on Artemisinin and Fenbendazole you'll see how far we have to go.