Urine Test Better Than PSA? |

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Күн бұрын

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@ThePCRI Ай бұрын

Timestamps: 0:49 What is the MiPS2 test and how does it work? 2:14 Can urine tests be used as a partial substitute for biopsies? 4:52 How does the 95% accuracy rate of urine tests affect the screening process? 7:17 What percentage of cancer is missed by different screening methods? 9:25 Can a PSMA scan cover the blind spots of an MRI? 9:58 Does MiPS2 function similarly to other urine tests? 11:15 Are urine tests helpful for those who don't have access to an MRI? 12:02 Is there much in the way of useful reporting data related to MiPS2? 13:43 Can PSA density provide information about the potential presence of cancer? 14:50 Are urine tests helpful for patients with more standard PSA levels? 16:46 Alex's conclusions

@Gary-e6y 21 күн бұрын

This is my go-to team for the most accurate and informative answers of understanding prostate cancer. Thank you.

@JayPatel101 Ай бұрын

It's so helpful listening to Dr. Scholz. Thank you for all the great content around Prostate cancer PCRI puts out.

@JamesBond-jj7dl Ай бұрын

I started with a psa going from 2 to 4 about 25 years ago; I’m 74 now. It has continued to creep up over the years and now it is 14, down from 16 2 years ago. I’ve had bph for many years also. Was seen by the head of Urology at NIH 3 or 4 years ago, had the MRIs, etc, 3-4 spots looked suspicious, and those 4 spots were sampled in addition to 8 other areas. Results? No cancer. The Dr said, because I have bph, of course I will have a higher psa #!! The larger the prostate, the higher the psa #. Simple!!! He said not To Worry at my age and the slow increase of the psa number is normal. He said I may get prostate cancer in the future but I will probably die from Something else….but not prostate cancer. Thank God!

@colemant6845 Ай бұрын

Alex Scholz asks the BEST, most relevant questions that covers the the topics we patients (and Doctors) want to know/hear. Very well thought out and structured presentation. Well done. Thank You.

@luismart7714 5 күн бұрын

It is clear that she knows the subject matter, but she doesn’t want to take the spotlight from the person being interviewed. She is great!

@bmurray3198 Ай бұрын

As a 61 year old, my PSA had never been above a 4.0, although it increased from 2.7 to 4.0 over the course of 18 months. Concerned about this modest to minor PSA increase, my PCP referred me to a urologist. On my first visit to my urologist I was asked to provide a urine sample. I didn't know there was a relationship between urine and prostate cancer, but I did what I was asked and, of course, provided the urine sample. At my second visit, and, coincidentally on my last day of work before I retired, my urologist shared that there was a high likelihood that I had prostate cancer based on my urine test results. That led to a prostate biopsy that confirmed that I did, in fact, have prostate cancer. Three months later (one year ago today) I had brachytherapy, and my PSA after last month's test was 0.28, down from 0.37 five months ago and 0.58 nine months ago. The urine test played an important role in my diagnosis and I am thankful that my urologist used that test to help diagnose my cancer.

@craftsmanctfl3493 Ай бұрын

@@bmurray3198 I’m a bit confused about the measurements of a PSA test. Is .38 the same as 3.8 or is it actually just .38 of 1%?

@schmingusss Ай бұрын

@@craftsmanctfl3493 I think it means .38 ng/ per ml of blood

@bmurray3198 Ай бұрын

@@craftsmanctfl3493 0.38 is not the same as 3.8. 3.8 is ten times higher than 0.38. PSA value is not a percent of 1.0.

@jp7357 Ай бұрын

@bmurray3198 Good to know. I’m 66yo, decided I need a relationship with a urologist and they mentioned a urine test. I’m surprised that a rise of. 2.7 to 4 over 18 mo was an alarm and did indeed indicate cancer. I’ve always heard 4 was the upper end of the”OK”. In your case it was the rise in PSA over time that triggered. Anyway, really good data in your post. Thank you.

@JimArmstrongField Ай бұрын

@@jp7357 A rapid rise in PSA can also indicate possible prostate cancer, even if it's under 4.0.

@Murhillwoodwork Ай бұрын

Thanks for all the great information that you provide. Alex, you are a wonderful interviewer !

@leonardola9161 Ай бұрын

Both of you are the best🎉

@garywhaley9164 Ай бұрын

Great job.

@briangriffith2394 Ай бұрын

Thank you so much

@jimzaino1211 Ай бұрын

Thank you so much for your information. It will be a year in December of 24 since i had my surgery. Im 58 yrs old and decided to have prostate removed with a 3+4 gleason score. I did PSA test for a year and the finally did the URINE test and thats what made me proceed with the MRI FUSION. Thats when it was noticed that a small cancer was in the prostate. It never penatrated the prostate, but i decided to have it removed. It definitely changed my life in 1 day but i believe i chose the right thing todo. I feel great . So for anybody watching these videos they are amazing and i would recommend keep watching there so educational. Good luck everyone, and KEEP ON KEEPING ON.

@antoniodelrey164 Ай бұрын

I had a urine test at same time of PSA and PSA was done right after digital and was elevated (6 something) but that was same as it had been for a couple years and was just after a digital. However the doctor ordered a biopsy and I was doubtful but he said he did feel a little something during digital. Not horrible but something…anyway, the biopsy results were 3 +4 in one place only. Opted for active surveillance and 6 month follow-up biopsy had become 4+3 in same one location and PSMA Pet/ MRI indicated slightly larger lesion but still in one place and no spread. Now I will have NANO knife and am hoping for the best. Long story short is that the biopsy still is the best and most accurate test as the PSMA Pet/MRI didn’t show the change to 4+3. At least it was for me.BTW I am now 72 and my local urologist never did a digital and said that PSA after 70 was no longer needed. Good thing I went to the big city university hospital an hour away. My biopsy was mri and ultrasound guided. Local only did ultrasound and I kept asking for mri and ultrasound guided but they said I had to have ultrasound guided first due to insurance so what it boiled down to is that they did not have mri with ultrasound capabilities. Go to the big city university hospital if you can is my suggestion. Dr. Is right. Don’t settle for probably …I understand that there is a conference coming up this coming week in San Diego. I believe that FOCAl therapy is the topic but may be just one of many. Would be great to hear about the conference…

@craftsmanctfl3493 Ай бұрын

Another advantage of having a urine test is that indication of another cancer might show up in the test results. There could be occult blood (invisible to the naked eye) determined from the test that could be related to, say, bladder cancer.

@jeffsmith7740 Ай бұрын

Good information, thank you

@ThePCRI Ай бұрын

If you have questions about prostate cancer and need help from our Helpline team, you can email us here: help@pcri.org

@maxthemagition Ай бұрын

I went to the local doctor because of frequency and urgency and got the PSA MRI Hormone Therapy and Radiation treatment for Prostate cancer as it was discovered that I had unfavourable intermediate prostate cancer. That was over a year ago and I still suffer urgency and frequency and weak flow. In fact I had to use catheters for 3 months. The question on my mind today is that the reason for my original problems was an enlarged prostate and now it is the same, but I was told by a surgeon that it was impossible to operate on my prostate because I have had radiation treatment. Why was my enlarged prostate not operated on before it radiated? Surely this would have cured my original complaint first and foremost? I am 77 years old and I am told that most older men start this awful journey after going to the doctor complaining about their peeing. I am in the UK being treated by our Wonderful NHS.

@scoot77777 Ай бұрын

I am a U.S Air Force Veteran 20yrs 64 yrs old PSA 7.1 up from 5.1 a year ago I have had a Prostrate Pacific MRI with contrast. And a PMSA / PET Scan and now they want to do an Trans-perennial Biopsy. The VA is extremely difficult to communicate and schedule appointments. The PMSA results which showed a malignant neoplasm…… Do you think this urine test would benefit me. I am still extremely not happy having to do the Biopsy, I asked the Doctor based on what we know why can’t we just treat it and forgo the Biopsy? I would very much appreciate your input. It’s been 13 months and still requesting treatment…….. Thank you both 🙏 I always enjoy your videos🙏

@TERRY-cb2ku Ай бұрын

I also had elevated PSA levels, had the MRI with contrast and discovered a lesion. But, I agreed to the biopsy and had 14 cores taken. 12 random and two in the lesion. Very diseased prostate but no malignancy. Perhaps you should consider getting a combination random plus targeted biopsy. Just a thought.

@scoot77777 Ай бұрын

@@TERRY-cb2ku Hi Terry, Thank you for your reply🙏 that’s great news! Yes, I agree with you I am going to have to surrender to the Biopsy it’s the only way to know what’s really going on inside my prostrate. Happy Holidays to you and yours😊🇺🇸

@marguit71 Ай бұрын

Terry - did you have the transrectal or transperineal biopsy?

@scoot77777 Ай бұрын

@@marguit71 Hi Terry I am getting the trans-perineal less risk of infection Ray 🇺🇸

@marguit71 Ай бұрын

@@scoot77777 I agree. That’s what I will be doing as well. My brother-in-law had a transrectal biopsy and was in ICU for days with a sepsis infection.

@myviews2u772 Ай бұрын

My 67 yr old partner had his prostate surgically removed 2 years ago by robotic keyhole method after having 6/8 biopsies detecting cancer(under MRI). His prostate was on the larger size. Post surgery his PSA was initially zero then over months slowly rose to 2 by June this year then 3 months later to 4. No repeat PSA was done at 4. Today he had a PSMA PET scan which is only showing an indeterminate area in one of his 'sit ' bones. Nothing else is evident. I think I heard the specialist mention that the scan has a 80 per cent false negative at PSA 4 but a 20% false negative when done at a PSA of 10. I am not sure I fully understand exactly what this means. I realise PET scans are not 100% accurate. The plan is to keep doing 3 month PSAs and another PSMA PET scan when reaches 10. In our country we paid for private care as the public system is a long wait. We do not have health insurance. If the cancer has entered his hip bone what are the treatments? Thank you.

@suzannahwhite4292 Ай бұрын

Are the MiPS2 tests useful in patients who have been diagnosed with PCs, treated with hormone blockers and RT and then one year after stopping ADT their PSA doubles within 3 months? How do we find out if the PSA (0.27) is down to remaining prostate cells kicking out PSA or a return of cancer?

@eugeneware418 Ай бұрын

In 2021 based on my biopsy I was diagnosed with lograde cancer. I had HDR Brachytherapy treatments and while having two PSMAs where NO cancer was found, my PSA level continues to rise and most recent (Sept 2024) level was 10.8. My quest is why does my PSA rise so high without the presence of prostate cancer?

@martinblunier707 Ай бұрын

what is more accurate? PMSA/Pet scann or MRI to see if cancer cells are growing or shrinking?

@kendavis1198 Ай бұрын

I just had my yearly Physical with my GP, My PSA count went "DOWN"??? From 2.05 to 1.45???? My concern is WHY??? I am on Heart Medication and Cholesterol Lowering meds and have read that that can effect the #??? I been on these meds now since AUG 30th 2020 and Nothing else has changed?? So "WHY" Did my PSA Drop like That??? I'am on the schedule for my Yearly EXAM with my Urologist at the end of this MONTH OCT 2024. So, I don't understand what has happened??? And I do Have the ever so famous "BPH"....

@ceciliaclark9406 Ай бұрын

I wanna know what does it take for a doctor to do a PSA? Or a prostate check, let alone a urine sample.

@threeftr3349 12 күн бұрын

You need a urologist

@ceciliaclark9406 12 күн бұрын

@threeftr3349 you also need your primary care physicians to send a referral.

@threeftr3349 11 күн бұрын

@@ceciliaclark9406 Yes, it all depends on your insurance. Many need referrals, but your doctor should not have an issue giving you one, if you want a prostate check. All the tests you mention is routinely done at urologist office. You could also get a list of urologists in your network that your insurance would accept. Then research the best one, then get your doctor to refer you. You have to be your own patient advocate. If you don't like your doctor well get another one. When serious medical issue come up, don't be rushed into a treatment plan or surgery, you need to do your own research. That's the reason I watch this channel, I spent months researching for my husband when he was diagnosed with prostate ca in Nov 23. There is so much to learn if you truly want to participate in your healthcare. It was his urologist who found the cancer, when it wasn't even on our minds, and helped find an amazing oncologist,. We ended up with 2 oncologists in 2 different states, and so grateful his cancer was caught early, and he's finished with his treatments.

@threeftr3349 11 күн бұрын

@@ceciliaclark9406 Yes, many insurance company requires it. Your doctor should not have any issue referring you, for a prostate check. The tests you mentioned is routinely performed at an urologist office. If your doctor doesn't want to...well, I say you need a new doctor. My husband's cancer was found because of his urologist, when cancer was not on our minds.. The amazing oncologist she referred turned out to be a top oncologist in another state that actually has been on this channel. He ended up with 2 oncologist. We are very grateful his cancer was found early, and he has completed is treatments. This channel helped us tremendously understand all of the testing and options that is now available. We participate in our healthcare decisions. From the cancer diagnosis to the end of treatment, we spent hours upon hours, with lots of note taking to learn, and understand the whole process.

@threeftr3349 11 күн бұрын

@@ceciliaclark9406 Yes, many insurance company requires it. Your doctor should not have any issue referring you, for a prostate check. The tests you mentioned is routinely performed at an urologist office. If your doctor doesn't want to...well, I say you need a new doctor. My husband's cancer was found because of his urologist, when cancer was not on in our minds.. The amazing oncologist she referred turned out to be a top oncologist in another state that actually has been on this channel. He needed up with 2 oncologist. We are very grateful his cancer was found early, and he has completed is treatments. This channel helped us tremendously understand all of the testing and options that is now available. We participate in our heartcare decisions. From the cancer diagnosis to the end of treatment, we spent hours upon hours, with lots of note taking to learn, and understand the whole process.

@hassansadik8597 26 күн бұрын

Do u have to fast to take urine test PS2 thank u

@raad684 Ай бұрын

Had an MRI, small nodule showing a pirad3. Had a isopsa, showed 4.9. Is this test an additional tool to the isopsa to rule out high grade? Or which is better- do they compliment each other? PSA is 4.7

@dingr Ай бұрын

I cannot find any information about MiPS2. But lots of hits on MPS2 and MPS2+ urine tests for PCa screening.. Are they the same test?

@ΔρΔημήτριοςΓκέλης Ай бұрын

Congratulation, you are doing excellent work. Please speak more slowly and clearly, the older age audience, like me, has slower ability of understanding your speaking. Especially the non Americans need more time to comprehend your English. Thank you.

@jimchoff Ай бұрын

You can change the playback speed. That might help. Also, turn on closed captioning.

@NoyesNewman Ай бұрын

65103 Gaylord Lodge

@colemant6845 Ай бұрын

Again: Your site is our ONLY source of CURRENT Prostate Cancer information. My PSA increase after 11 year past radiation treatment has resulted in 3 BIOPSIES ( all Benign!) Yet 2 PSMA's showing cancer in the prostate. Now my Urologist are all CONFUSED and say I am a "Wait and See " Patient. PSA test every 90 days. I am NOT comfortable with that. This is NOT a Science.

@gmv0553 Ай бұрын

Have you had a MRI? A MRI saved my life showing cancer in the top of the prostate. A MRI biopsy verified the cancer!

@colemant6845 Ай бұрын

@@gmv0553 Yes , 2 .. Both Negative and the my PSA continued to climb. My Urologist are confused and just put me on a "Wait and See" protocol. This makes me uncomfortable That is my situation.

@schmingusss Ай бұрын

@@gmv0553 Did you have a prostatectomy?

@scottroewe Ай бұрын

Thank you thank you…what are the recent developments with MRI’s I am due to get an mri at tower imaging in Santa Monica is there something specific I should ask for?

@colemant6845 5 күн бұрын

@@schmingusss I had High Dose Radiation (a type of Brachytherapy). My PSA dropped to .3 and stayed there for 10 years. Just recently started to climb again.

@maxthemagition Ай бұрын