Using Luciferase Reporter Cell Lines for High Throughput Screening Readouts

Reporter cell lines are critical tools that serve as models for tissue types or disease states, engineered to express a reporter protein, such as luciferase, upon exogenous stimulation. Using reporter cell lines provides a convenient and simple readout to screen for inhibitors of protein signaling or activation. This video reviews the uses and advantages of reporter cell lines in the context of cellular research.
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