Valneva | How does Valneva work

[@Progen77]

We need more vaccine choices in America, Novavax and Valneva ASAP.

[@friendlyneighborhoodimmuno7192]

Yes I agree!

[@ArmonMitchell]

Not if Big Pharma Lobby and Bill Gates have anything to say about it

[@terjeoseberg990]

@@ArmonMitchell, Why would Bill Gates care? I bet he funded Novavax when he gave $1B to each of 7 vaccine companies before Trump’s Operation Warp Speed.

[@terjeoseberg990]

@@ArmonMitchell, “Here's how a struggling company won $1.6 billion to make a coronavirus vaccine” “In late February, as the coronavirus spread around the world, Dr Richard Hatchett, head of an international nonprofit that gives money to vaccine developers, got on an important call to discuss vaccine candidates after his plane touched down at London’s Heathrow Airport. Executives from the Bill & Melinda Gates Foundation, which helped found and finance the nonprofit, were on the line, enthusiastic about Novavax, a small biotech company they thought had the potential to develop a vaccine against the virus - fast.”

[@terjeoseberg990]

@@ArmonMitchell, “Gates, whose foundation has donated millions to coronavirus vaccine and treatment research, told CNBC that the two vaccines, which have not yet been authorized for use in the United States, can be effective against coronavirus mutations. People understand that "there is reduced efficacy, although Novavax and Johnson & Johnson still retain a lot of capability against those variants," he told CNBC's Andrew Ross Sorkin in an interview that aired Thursday on "Squawk Box."”

[@ChristiansPrayingTogether]

From what I have read, half of Valneva is being produced in California and sent to France, where the other half is added. The vaccine is not available in the USA 😭 but is being used in Europe. I'd really like to see more vaccines offered in the USA, there's no reason not to other than greed. It's very sad.

[@thechosen4403]

kzbin.infoM0UKBzM4kXQ?feature=share PLEASE WAKE UP

[@cassandrajackson8560]

I love the chart that breaks down each vaccine. As a nurse, I chose the J&J, I wanted my DNA to code the protein against the virus and not someone else. My DNA know me a whole lot better. Great information! 😊

[@danield.1707]

I am still afraid of the CpG in the Valneva vac. Would u please make a additional video about it 🙏

[@ianrobertson2282]

Thank you for this informative video. I am hoping to hold off from vaccination until Valneva becomes available in Australia.

[@lisa8275]

I have not seen any mention of Valneva coming to Australia. The Novavax is - 51M doses purchased Dec 2019 due here by year end, all going well.

[@sofascialistadankulamegado1781]

You will be waiting for seemingly forever then. Moderna, pfizer and astrazeneca available in Australia are the most effective vaccines known and have lots of data surrounding their efficacy and risk profile. Why would you wait for a vaccine that gives comparatively short term immunity just like Novavax?

[@lisa8275]

@@sofascialistadankulamegado1781 it seems that Pfizer wants to give booster shots every 6 mths at least; if I have that correct. So do you have information that Novavax lasts less than 6 mths? If you look into it more closely I think you may find that most people wanting to wait for Novavax have pre-existing conditions/personal or family health histories around clotting, palsy etc & the adverse events databases have many instances of those types of reactions occurring with the currently available vaccines. Results from Novavax trials have shown less adverse effects so it looks promising for those with valid health concerns. It may be a while before we have a one size fits all solution like our current arsenal of vaccines. 😉

[@mandym9469]

Do you think it ever will??

[@ianrobertson2282]

@@mandym9469 I hope so, but the pressure to have one of the current less than effective vaccines is growing. There are over 250 covid vaccines being developed at the moment so some of those will be better than the mRNA shots, having been developed using tried and proven techniques.

[@LaDebby1]

I hope Valneva vaccine will be available in Italy ASAP, because I don' t trust mRNA vaccines and Valneva is a traditional one, and I'm less afraid of side effects in a long time.

[@christinekulper7824]

I'm also in Italy. Yes, we need this Valneva quickly so we can work. Have you heard anything more about this vaccine?

[@sanjumhoudi9601]

Each time I gain a bit of understanding of how our bodies work I float in sea of wonder .... so beautiful ... can't describe it

[@friendlyneighborhoodimmuno7192]

I agree. Our immune system is amazing and there’s still more mysteries to solve.

[@langeveldy]

Lucid exposition. Thank you. The vaccines comparison table at the end of the video is helpful.

[@friendlyneighborhoodimmuno7192]

Thanks!

[@kishidabu]

Thanks so much for the detailed explanation of Valneva and its adjuvants. I am in the Valneva clinical trial for the older cohort study in New Zealand and was curious about all of the details.

[@dorinnaforest8937]

From what I read, Valneva does the inactivation by chemical beta-propriolactone BPL. This is a disinfectant. I would like to know how its gets filtered out or neutralized afterwards, since it is a human carcinogen. There must be a way, since it is also used to sterilize blood plasmas

[@Cristina091]

You know that the meaning of neutralizing is to prevent the expected reaction. Exactly, the BPL works as a neutralizer to inactivate the virus, it's necessary the product BPL, which (in low quantities) is responsible for maintaining the antigens of the native virus to preserve protective immunity.

[@vovi547]

I'm in the UK and Novavax seems way off still, so I'm not expecting we will see this new one anytime soon. We should have choice not just this approach of you get what you get on the day.

[@themaskedmaestro4699]

We should definitely have a choice. I was so gutted when the UK cancelled the valneva vaccine. It seems the UK are set on an mRNA only approach. I wouldn't mind hopping on a train to france to get valneva when it comes out there tbh

[@mchobbit2951]

I really hope that we will get Valneva or Novavax in the EU. I'm not taking the mRNA ones no matter what.

[@ashleyadam955]

No mrna for me

[@doncryptonium5160]

Hey There! Thank you for your videos. I love both vaccines Novavax and valneva. But here is where I have some questions. Novavax seems to elict mainly humoral immunity which seems to drop fast after a while. It is quite hard to find reports on the cellural immunity. While Valneva is promising here despite not having such repid humoral immunity we get broad response including cellural with very mild adjuvant. If you'd have to guess which ones would be prefered covid vaccines in following years?

[@friendlyneighborhoodimmuno7192]

I agree it's hard to find published studies comparing how well each vaccines makes cellular versus humoral immunity. It seems like the viral vector vaccines and mRNA vaccines make the most memory T cell responses. Between Valneva and Novavax, it would have to be a guess then. It is likely that Valneva contains more toll-like receptor ligands and therefore will activate more innate immune cells and T cells.

[@thechosen4403]

kzbin.infoM0UKBzM4kXQ?feature=share PLEASE WAKE UP

[@dezafinado]

Just get one of the available vaccines... once your immune system is in full force. Go kiss every person at the supermarket and get yourself infected. That's what I got... the full monty. I glow in the dark now. I breathe on the sick and they get healthy.

[@adamadkins4485]

When are they putting these vaccines out. The novavax and valneva

[@caseysinclair2915]

How does the safety profile of valneva compare to novavax?

[@friendlyneighborhoodimmuno7192]

Great question. I don’t have any side by side. Neither of those vaccines has had a major adverse reaction reported yet, but Novavax has been tested on more people.

[@caseysinclair2915]

@@friendlyneighborhoodimmuno7192 thank you. What do you make of the suggestion that novavax is safer due to the finite amount of spike protein VS the variable amounts produced with the mrna vaccines?

[@friendlyneighborhoodimmuno7192]

@@caseysinclair2915 That is a great question. I think for some people Novavax is a safer and better choice because of the smaller amount of spike proteins. For example, several commenters have mentioned they have allergies and auto-immune diseases and their doctors recommended they wait for Novavax. On the other hand, the mRNA vaccines have higher efficacy against variants. So it depends on what each person needs.

[@caseysinclair2915]

@@friendlyneighborhoodimmuno7192 thank you 👍 safety > efficacy for me.

[@RomanoPRODUCTION]

Do you think Valneva vaccine will remain in the muscle when injected? Or it can drain/leak into the lymphatic system like mRNA shots who are coated with liposomal cholesterol? thank you. Have a nice day.

[@friendlyneighborhoodimmuno7192]

Interesting question. I haven’t seen any distribution data yet. A small percentage probably does circulate and get broken down in the liver.

[@jamest3552]

Can you comment on Novovax and Valneva as they relate to capillary clotting, particularly in the non-regenerative organs? Thank you.

[@friendlyneighborhoodimmuno7192]

I haven't seen any data on clotting for either vaccine. All I can say is that so far there are zero reports of blood clots in either clinical trial.

[@terjeoseberg990]

The mRNA and adenovirus vaccine don’t use an adjuvant, but could using adjuvant improve the performance so they could use a smaller dose?

[@jobegs]

Great question!

[@friendlyneighborhoodimmuno7192]

Fascinating idea. Yes that could potentially work. The spike protein creation in the mRNA vaccines triggers the Toll-like receptors and the adenovirus itself triggers the Toll-like receptors, so in a way those vaccines have adjuvant properties built into them.

[@jasrx947]

Doesn't the moderna vaccine have an adjuvant called Matrix M I believe?

[@jasrx947]

Sorry mrna vaccines do not contain adjuvants. Novavax contains Matrix M

[@denagorilik]

You say "no vero cells in the shots", so this cannot give you tumors, right? Please explain more.

[@konradpovac5424]

I take this if is availbe in germany. .or can I take this in france

[@adamadkins4485]

I would trust those over the other ones sense they are going through proper testing. I will take valneva or novavax.

[@mchobbit2951]

Same. I'm sitting in Germany, forced to test for the privilege of working and not allowed to do much else because I refused to take the mRNA crap. I'm holding out for Valneva or Novavax.

[@montagnesaintegenevieve5177]

Thank you very much. Do you have some thoughts to share about the alum adjuvant? Some groups of doctors say that it might be dangerous, and that alum may induce, between other problems, Creutzfeld-Jacob disease. What is your opinion about this? All my thanks by advance.

[@Nyruami]

As a friendly neighborhood immunologist, you should maybe have pointed out that 4000 persons are way too few for a phase 3 study. Maybe you should also have pointed out that the Valneva phase 3 study didn´t use a placebo control group. The control group got the Astra Zeneca vaccine. By this setup alone, the study is completely useless. In 4000 persons there are no severe outcomes because there are little to no infections. Maybe you should also have pointed out that CpG, the enzyme you seemed so happy about, is completely new, so Valneva is not the well-known vaccine we use for 60 to 80 years. There is only one other vaccine using CpG, and this vaccine has been approved less than 10 months ago. Also, this vaccine is rarely used, so there is little to no knowledge about CpG and its side effects. Most importantly, I really would have liked you to mention that vaccinating against Corona is pretty much stupid in the first place, as mathematically for every person that is protected against medium to severe outcomes there is a multitude of persons going through medium to severe vaccine side effects. And this ratio only worsens with each additional booster jab.

[@dezafinado]

Not so sure about increasing side effect with booster shots. Most of my coworkers who are 55+ yrs old already got the 3rd jab (all mRNA), side effects were much less than the 2nd shot. Just saying this is what I see in real life.

[@Nyruami]

@@dezafinado Just google Ontario study, numbers don´t lie

[@dezafinado]

Well .. Ontario Study gave links to exchange study. Btw, the best way to lie is by numbers, by statistics.

[@Nyruami]

@@dezafinado Well, sure, the public health service in Ontario is lying. You know the problem with you brainwashed propaganda victims is, that you don´t even accept facts as facts anymore. You are already at the status of religion, you just believe no matter what reality has say.

[@dezafinado]

@@Nyruami you're a bit smarty. Show me the links. When I said to lie by statistics, that's the first thing they teach you in Statistics 101. Ontario study doesn't lie but CDC does. You see there... they all use data.

[@tiagofaria8064]

Hello, first of all thank you for your video. I would like to ask you, with what we know now what vaccine: 1 Gives the best protection for the long term; 2 What can be the safer vaccine from all those available.

[@fadyadel8062]

the novavax has 5 mcg spike protein ,how many mcg of spike proteins produced by pfizer 30 mcg of mRNA ? is it 30 mcg and how this can differ from one individual to another ? is the ability of cells to produce protein from mrna vary depending to age groups ?is that why teenagers get more myocarditis ?are their cells produce more spike proteins than 70 year old patient ?any reason why side effects from second shot of pfizer is always worse while astrazenica behave in the opposite way

[@stevenlyhne1]

Thanks for your video. Are the spike proteins of Valneva less cytotoxic than the spike proteins of mRNA and adenovirus vaccines?

[@tonyg4058]

The dodgiest thing about the mRNA vaccine is that your own cells are instructed to produce the spike protein. Whereas with Valneva I believe the spike protein is in the vaccine itself and your body mounts a response. I may be wrong on this, someone correct me if I am wrong? But if I am right, that is enough for me to opt for Valneva and Novavax instead.

[@jdoe5873]

@@tonyg4058 Can’t answer but just wanna flag that Valneva has the whole virus. Novavax, on the other hand, only has the spike protein part of the virus.

[@sofascialistadankulamegado1781]

@@tonyg4058 cytotoxicity from a vaccine is miniscule compared to the cytotoxicity of a sars-cov2 infection. When your own cells produce the spike protein or whether you get it directly, it makes absolutely no difference. Both are very temporary vaccination effects but do the same thing in the end.

[@adohko]

So, I have an excellent immune system. The last time I was sick was in December 2019, and it lasted for two days only. Before that it was in 2017. The trick is to catch symptoms as early as possible, stay home and do what works for you. Anyhow, I am WAY more concerned about potential adverse effects of the vaccines, than their efficacy. If it’s above 60% it’s good enough for me. So my question here is, what do we know about the potential adverse effects of Valneva? I’m not talking about typical side effects like sore arm, headache, etc. I’m talking about things like blood clots, heart issues, Guillen-barre syndrome, and the like. Thank you!

[@friendlyneighborhoodimmuno7192]

Good question. Valneva just published their phase III clinical trial results. So far no serious adverse side effects have been reported. valneva.com/press-release/valneva-reports-positive-phase-3-results-for-inactivated-adjuvanted-covid-19-vaccine-candidate-vla2001/

[@adohko]

@@friendlyneighborhoodimmuno7192 Ah, good to know - Thank you for the link!

[@arymhansie]

Doc , you say that the Valneva is similar to the Polio vaccine-can you explain the similarity? The Polio is really trialed for many years, what may be the long term effects??

[@friendlyneighborhoodimmuno7192]

Yes, the similarity is that they are both whole inactivated virus vaccines which are made in immortalized monkey cells. Whole inactivated virus vaccines have been tested for decades and are very safe.

[@arymhansie]

@@friendlyneighborhoodimmuno7192 Thank you for answering, do you think that it will be suitable for someone with allergies? Somehow this appears to be a better vaccine than even the Novavax. Since the inactivated virus vaccines are so safe why didn't others (Moderna, AZ, Pfizer) think of formulating their vaccines based on such a tried and tested formula? Sorry for so many questions.

[@themaskedmaestro4699]

@@arymhansie If you're still after an answer, it's because according to pfizer's results, the effectiveness of an mRNA vaccine is higher than the effectiveness of an inactivated whole virus. The whole virus may be a lot safer than mRNA but the regulators have judged mRNA to be "safe enough". I am personally waiting for a whole virus vaccine because I'm not comfortable with mRNA. I would rather have something with decades of long term safety data.

[@hundertprozent100]

Wich vaccine would u choose. And why Im from germany. And not vaccinenated yet.

[@wadestewart5504]

Will this be available in Canada/north America? And when? Same for Covaxin and Sinovax

[@friendlyneighborhoodimmuno7192]

It will probably be available in Canada before the US. I don't know why Covaxin and Sinovac are not approved for use in the US.

[@wadestewart5504]

@@friendlyneighborhoodimmuno7192 ok thank you

[@jaybeaton9301]

Valneva already has a presence in Quebec and politics being what they are here there's a good chance we will get it because it's Quebec.

[@leenababiker2078]

Thank you so much for your nice explanation, really appreciate it. What exactly Alim and CPG are? And they are harm the body cells? Thank you

[@friendlyneighborhoodimmuno7192]

Thanks Leena! Alum is aluminum or some version of it. Aluminum hydroxide or an aluminum salt are commonly used. They are in very small quantities in the shot. If you use anti-perspirant than you already regularly use Aluminum. CpG is a small part of a bacteria's DNA. It activates the immune system to help you form a memory T and B cell response and make antibodies.

[@leenababiker2078]

@@friendlyneighborhoodimmuno7192 Thank you so much for your reply and great information. So is this the same Aluminum they have been added to most of kids vaccines? I have heard the small aluminum particles would stay in some organs beside the brain and it might be the cause for some diseases like Autism for example.

[@friendlyneighborhoodimmuno7192]

@@leenababiker2078 yes it’s the same Aluminum that’s in kids vaccines. The person who put forward the aluminum causes Autism was found to have faked his research, and I haven’t seen any other research linking Aluminum and Autism.

[@leenababiker2078]

@@friendlyneighborhoodimmuno7192 Thank you. Appreciate your quick response and your kind patience to answer all my questions in details☺.

[@durschfalltv7505]

@@friendlyneighborhoodimmuno7192 This was such a great Video! I learned alot. I mean i learned most of it in school but i forgot about it and i didnt knew about the alum and CpG. I am a very skeptical person. Thats i why i don't trust the mRNA vaccines. I only like to use things that are very important to me if i can understand them. For example i am a big privacy advocat and try to only use software that is FOSS and follows unix philosophie. The thing about Whole incativated Virus vaccines is that i can understand it. I could recreate it. I could get the eqiupment and the materieals to make that vaccines. Which makes it Free and Opensource. And it follows the unix philosophie because it can be done decentralized. Allthough it's not done like that which is sad. It put's it in a spot like systemd. However i am very interested in this. Would you be able to make a totourial on how to (theoretically) make this vaccine? Like a touturial that if you had the time and money you would be able to use that toutourial to make a working Whole inactivated virus vaccine. And could you explain every step in detail. So that we understand what we would be doing? Or if you cannot do that maybe you can link me just resources in the comments so i can easily learn. I would really like to get vaccinated i just have a problem with trust and i need knowledge. Thank you alot for this Video.

[@teama224]

Does getting 2 shots is a standardized way which gave the maximum efficacy on trials based on numbers, but really for some people 1 shot might be enough? Also people that recovered and tested positive for antibodies why is there no option that they prove antibodies for a immunity certificate? Last question even if antibodies are gone, wasn’t it true that memory cell could quickly mount an immune response for reinfection? Thanks, great video I wish I had a bio teacher like you!

[@durschfalltv7505]

yeah. i learned that too in biology. That even if the antibodies are gone that still b-memory cells would activate in a new infection and produce new antibodies after 3-4 Days. It would make you infectious. But still it would protect you from the worse.

[@ricknofzinger]

Your videos are the most understandable and educational that I have seen. I am in a quandary. I have not been vaccinated because I am terrified that the vaccines will negatively affect my immune system. I have Autoimmune Encephalitis (Thanks, again for the amazing video you presented on this topic). I am presently taking Ivermectin as a preventative against Covid-19. Do you have information on Ivermectin (pros and cons)? This Delta variant has made me second guess myself. Thank you.

[@davejordan5848]

Good Q...I'm sure the good doc will get to it soon. May I just say in your circumstances the idea of prophylaxis & building the strongest immunity are both key. The doc is bound to explain better than I, but the Ivermectin is able to act as a kind of delivery system for zinc (& Vit D3 is also key). So I trust you're taking the whole cocktail. It may even be a good idea to test your levels, so that you have an idea where your levels are now. For more detailed immune building cocktails, including elements our friendly immunologist has mentioned (e.g quercetin ) see also Peak Prosperity Dr Chris Martenson. Sounds like they have much understanding of this bug in common. Keep well 🙏🙏🙏

[@ricknofzinger]

@@davejordan5848 I have watched Chris since the beginning of this nightmare. I was unaware that quercetin was mentioned on this site. Did she speak of other immune builders. We take Ivermectin, Quercetin, Zinc, Vit C, VitD3, Melatonin and Magnesium. Still, every once in a while, I am tempted to get the vaccine.

[@friendlyneighborhoodimmuno7192]

Ah yes a video on Ivermectin is on the list, but there's a of controversy around it and I would need to do a lot of research and tread carefully. You are in a more complicated situation than most people, and I understand your concern.

[@lesseirgpapers9245]

In India I used HQC also aginst Roto Virus infections

[@ricknofzinger]

@@lesseirgpapers9245 I have used HQC also.

[@davejordan5848]

Thanks again doc...clear as always. May I add another topic for your consideration? How about your take on PCR tests (being discontinued Dec), their shortcomings & their replacement (multiplex?)? Please :-)

[@friendlyneighborhoodimmuno7192]

Thanks! I'll look into it. Might be a few weeks though. My video to do list is getting longer!

[@davejordan5848]

@@friendlyneighborhoodimmuno7192 Seems quite topical now... with the right headline it could draw a lot of eyes. You'll have to figure out carefully how to keep it succinct by preparing some of the visual aids, just like you did very smartly in this one. Keep up the good work 👏👏👏

[@friendlyneighborhoodimmuno7192]

@@davejordan5848 Thanks for the support.

[@tollylocana9746]

Can you do a video on the astra and Pfizer shots please because you explain things very thoroughly and I am confused about what goes on in those ones

[@friendlyneighborhoodimmuno7192]

Thank you! My very first video is on how the mRNA vaccines work. kzbin.info/www/bejne/m6Wak3qLac2Vj6c

[@ktolwal]

can u please tell me , if this is better than Novavax?

[@friendlyneighborhoodimmuno7192]

Sorry it's too difficult to compare, and not enough data is available. They both have minimal side effect profiles, but Valneva doesn't have efficacy data yet.

[@ktolwal]

@@friendlyneighborhoodimmuno7192 I do understand your point, however purely in terms of functionality which one do you think is effective, safe. I just want the coolest one in terms of r&d.

[@ChristiansPrayingTogether]

A very informative and beautiful talk ! Thank you soooo much ! This is fabulous. I wish Valneva was here in the USA.

[@friendlyneighborhoodimmuno7192]

I also wish people had a whole inactivated vaccine option.

[@DrKCarlucci]

Thank you for the lecture. It seems the whole killed makes most sense and would give more “well rounded” immunity vs. just a piece of the virus. Does the alhydroxyquim- II have known side effects?

[@TheTeamdom]

Does Valneva work against Omikron? Thanks.

[@dimitrios0072]

Is this the most natural vaccine? More natural than novavax?

[@friendlyneighborhoodimmuno7192]

Yes it is.

[@dimitrios0072]

@@friendlyneighborhoodimmuno7192 thanks so much. This the most safest vaccine then ;)

[@smartengineering8934]

If the Valneva shot gets antibodies produced against more proteins than just the spike protein, wouldn't it stand to reason that it would be more effective against variants than mRNA shots, which only get antibodies against the spike protein produced?

[@friendlyneighborhoodimmuno7192]

Good question! The logic of many varied antibodies over one type of antibody does make sense. There is no head to head data between Valneva and Pfizer or Moderna. If you look at the other whole inactivated vaccines like Sinovac or Covaxin their efficacy is a little lower than the mRNA vaccines. This could be due to many variables that we can't account for. It may be that the mRNA vaccines cause more antibody production or that the antibodies last longer, but in the real world comparing data across countries is very difficult. All of the vaccines are keeping people out of the hospital, so that's something they have in common. Also the spike protein can't mutate too much or the coronavirus won't be able to use it to get into our cells, since the spike protein must conserve the key region which binds to ACE2.

[@ashleyadam955]

I like the valneva

[@brankabogdansr8823]

I am in Slovenia. How can I GET it?

[@harbingerofevil]

Awesome, TYVM!

[@whatstrue8936]

How likely is an ADE reaction with those vaccines?

[@friendlyneighborhoodimmuno7192]

I have a video on ADE and vaccination. It's not likely with Valneva or any of the other whole inactivated vaccines. Right now there is not evidence for ADE, but researchers and doctors are keeping a close eye on it.

[@whatstrue8936]

@@friendlyneighborhoodimmuno7192 I missed that one then. I'm going to look for it. Thank you very much 🙏

[@Kueytwo]

Mitochondria is in each cell and is like a Bacteria that is symbiotic. Is it totally guaranteed that no stem cells are in the vaccine, and it can not attack the mitochondria to make cancer cells? Is the inactivated whole coronavirus being made and provided by France, or made and provided for by the USA? The standards are very different, like what is acceptable in food items for human consumption (Nestle).

[@durschfalltv7505]

I always wondered why nobody makes a covid-19 variant that is extremly contangious but has almost no symptoms that only produces viruses with tissue that is easily regrowing and doesn't cause permanent harm. Just release and bam everyone gets immunized. Or is this the reason why we are in this pandemic afterall? Because covid-19 was supposed to be that. I think gain of function isnt that bad. If safety Standarts are fullfilled strictly. Is anyone working on a solution for corona like that currently?

[@clementepinos6848]

There's someone working on.this solution right now: nature itself. The virus is evolving to be more contagious, but less deadly. Deadly viruses kill their host, and they die with their host. Non-lethal viruses don't kill their host, and this allows the host to spread it; this has been the tendency with SARS-cov2. This is natural selection. Everyone gets infected with a non-lethal coronavirus, gets inmunized, people stop dying, and a balance is reached. So nature itself (or god) is ending this pandemic.

[@adohko]

Is it better to have a longer time period between the two shots?

[@friendlyneighborhoodimmuno7192]

That's a great question which has not been tested. In the clinical trials, only 3 or 4 week spaces between shot have been tested. If this wasn't a pandemic, the spacing would likely be more like a regular vaccine schedule with months in between.

[@adohko]

@@friendlyneighborhoodimmuno7192 - Right! I’m no expert, but if the data says waning is on the order of about 6 months, getting your second dose after say 4 months should be better in the long run as it would extend your immune defenses for a longer period of time, which is a good thing given variants and such.

[@friendlyneighborhoodimmuno7192]

@@adohko I can see the logic in that. However initially to hit the high levels of antibodies needed for protection most data shows two shot are needed. Maybe the booster shot data will give us some info on how to space things in the future.

[@adohko]

@@friendlyneighborhoodimmuno7192 - Thanks! I’ve been looking on Quora and it appears there may be data to support the notion of delaying the second dose longer than just a few weeks, for longer lasting immunity. It varies depending on which vaccine though. A deeper dive into the topic would be interesting :)

[@partypoodlemama]

Hello, where did Valneva acquire the SARS-COV2 virus? Thought it was identified through insilico modeling- has it ever been isolated intact in infected individuals?

[@friendlyneighborhoodimmuno7192]

Good question. It has been isolated from multiple people in dozens of countries. You can search Pubmed where there are lots of peer reviewed science papers.

[@BigMamaDaveX]

😎 I came, I saw, I liked, and SUBBED.

[@ezzovonachalm7534]

Is there any GRAPHEN in the Valneva vaccine? Please answer with NO or UNFORTUNATELY YES !

[@konradpovac5424]

Why I Need nanoder particles in my Body ?

[@friendlyneighborhoodimmuno7192]

No graphene in Valneva.

[@konradpovac5424]

@@friendlyneighborhoodimmuno7192 and no nano particles?

[@rct999]

What will happen if you take all vaccine types at once?

[@TheCrayonMan529]

you become immortal

[@larrywong7834]

Will Novavax prevent majority hospitalizations upon Delta Variant infections??????

[@friendlyneighborhoodimmuno7192]

Great question. There’s no direct data on Novavax and Delta. However if you look at the other vaccines available, yes it will most likely keep most vaccinated people out of the hospital. Several of my friends in health care are reporting that 95-95% of people on ventilators are not vaccinated.

[@larrywong7834]

@@friendlyneighborhoodimmuno7192 Thank you. Our niece just started Virginia Commonwealth Univ Med School Honors guaranteed entry program. About 50 Top Grades graduating high school students qualify out of 800 applicants. You. Ms. MD, Phd Nice Nice Nice Lady is her role model.

[@johncavallini6929]

Does it contain graphene oxide or nano-particles?

[@friendlyneighborhoodimmuno7192]

No. It does not contain either.

[@mchobbit2951]

@@friendlyneighborhoodimmuno7192 Which is why it's my favourite choice so far. If it came down to it, I'd take Novavax, but the nanos do make me a bit nervous.

[@melvynbraithwaite8563]

Valneva is ok as it replaces the two VV that was killed in the Virus.It is replacewith VV green in Valneva!! UV light would have done the same replacement MBraithwaite Yorkshire Viking

[@danield.1707]

I learned about CpG, that this adjuvant also includes nanoparticles❗️

[@_a.z]

Good video!

[@friendlyneighborhoodimmuno7192]

Thanks!

[@celestialfix]

Super interesting!

[@petehuda7457]

Is it safer than mrna?

[@friendlyneighborhoodimmuno7192]

The mRNA vaccines only have adverse reactions in 0.01% of people, and there isn't exactly comparable data for Valneva. But your cells will not make the spike protein with Valneva, so it's likely there would be less side effects.

[@jaybeaton9301]

Thanks for doing this.

[@systemdeadlock]

Just awesome

[@friendlyneighborhoodimmuno7192]

Thank you kindly!

[@tadore5046]

Wonderfully explained. Thank you! I'm happy to like and subscribe. Looking forward to more data on Valneva!

[@friendlyneighborhoodimmuno7192]

Thank you!

[@yoursony]

It important to improve immunity by taking vaccine or health supplants. Vaccinated persons will take time to boost their immunity against virus.

[@patriciatremblay2058]

Is this tested on fetal cells? I was holding out hope for Novavax, but discovered that it WAS tested on fetal cells. 😔Thank you.

[@friendlyneighborhoodimmuno7192]

I have not seen this at all. Can you send me a link. I know KZbin sometimes removes links.

[@misterk3223]

Is the valneva vaccine tested on fetal cells?

[@ChristiansPrayingTogether]

I did a lot of research on Novavax because I'm with you on fetal cells. Their own site says no fetal cells ever used. I hope this is true. Keep researching it.

[@erikdog2430]

The dna....is that the way it actually looks like ....2 spirals joined?.....and whats inside them?....we are only beginning

[@estania]

Is this vaccine supposed to come to the USA?

[@friendlyneighborhoodimmuno7192]

As far as I know, there aren't any plans for Valneva to come to the USA.

[@ChristiansPrayingTogether]

Yet half of the shot is produced in California but we can't get it here ... Just crazy !

[@adohko]

Ok, one more question :) Let’s assume the WHO eventually approves Valneva, Novavax, and Covaxin, but it’s not available in the United States. Can I go to Europe or wherever they provide the vaccine, get it there, and be considered fully vaccinated in the United States? What’s the official deal on this? Does it vary per state? Thank you for being so responsive by the way. Subscribing! 😊

[@mchobbit2951]

For Novavax, the CDC granted "vaccinated status" to people who were vaccinated with it during the clinical trials. But generally speaking, nobody can tell you until they roll out the abovementioned vaccines. It can't be soon enough for me.

[@viktorfilipovic6955]

Its a french-austrian company.

[@erikakat1812]

Virus, cells are comprised of atoms (maybe). Are the vrus really inactive, or do they interact with cells in a way that we cannot see yet?? ....hypothectic

[@friendlyneighborhoodimmuno7192]

Inactivated and dead virus particles if they are in a certain shape (conformation) can interact with immune cells and activate internal and external receptors, but the virus cannot make copies of itself or kill your cells. So yes!

[@durschfalltv7505]

Come on guys get her to 5k!!

[@viktorfilipovic6955]

Biontech developed the vaccine, not pfizer, pfizer did logistics. I mean you don't credit your delivery man for cooking food that you bought right? Im just saying credit due where credit is deserved.

[@cocosilkworm]

and yet another one: "EnGeneIC has developed its EDV nanocell for oncology applications. EDVs have proven to behave as a therapeutic vaccine against COVID 19"

[@ezzovonachalm7534]

Unfortunately a confusing presentation only to conclude that we do not know the efficacy of this BUNGLE. Abis MD 26.11.21

[@bbseal6174]

I wish valneva was approved in usa the air force is gunna make me take the vaxx to join so ill have to go with novavax beause they wont approve valneva :(

[@marcbordeau1702]

Can you clarify the figures used for the two at the top of the chart are RRR FIGURES and not ARR FIGURES. THIS IS ONLY BECAUSE THE ARR FIGURES ARE 1.2% EFFICACY. COMPARED TO the RRR FIGURES OF 95% AS SOLD TO THE PUBLIC AS A LIE.

[@MK-ih6wp]

This is what initially made me realize we were being deceived about the jabs. Even the FDA guidelines tell manufacturers to use ARR (absolute risk reduction) instead of RRR (relative risk reduction), since RRR can be misleading. If they wanted consumers to be truly informed prior to giving consent, they should provide both ARR & RRR, since they each tells a different side of the story.

[@bosanpisan]

Will cause blood clot like J&J and AstraZeneca ? 😁

[@lubo8051]

do not forget to take zinc, D3 vitamin, beware of sick people around and do some sport outside

[@friendlyneighborhoodimmuno7192]

Yes exercise and vitamin D are great for the immune system.

[@aknahal]

this is unfortunately "chinese" for me, so i chose hot toddy inhalation instead

[@artpandemic4535]

This is OK at least

[@gardenvariety-]

Shouldnt an immunologist be talking about natural methods to boost the immune system more than vaccines?

[@friendlyneighborhoodimmuno7192]

In a regular year, but not right now. There is published scientific data that eating healthy and working out boosts your immune cell numbers and performance. However, hospital beds are full right now, so natural immunity has met it's match. People who are unvaccinated are 88-94% of the people who are in the hospital. Vaccines have worked to rid the world of Polio and Smallpox. Our immune systems are amazing but many people have reasons why their immune systems don't work well and they are at increased risk of lung damage and death from COVID. Natural immunity makes sure we can fight off almost any of the 800 cold viruses, but it doesn't fight off HIV or cancer without help. It's been a hundred years since humanity has been challenged by a global pandemic like this, so our immune systems do not have antibodies to help fight COVID unless you get vaccinated. Take care

[@gardenvariety-]

@@friendlyneighborhoodimmuno7192 but we cannot keep getting the vaccine after being vaccinated. You should add to that. Even vaccinated are getting admitted. Check Israel. Take care

[@MarbledPaladin]

@@gardenvariety- Booster shots = constant cash flow for the manufacturers... Vaccines alone are not the solution, we need medications for the people who get infected. Even if everyone in the world was vaccinated (which will not happen) people will still get covid (but hopefully with fewer symptoms) as the CURRENT vaccines do not protect vaccinated people against catching covid and transmitting it to others...

[@BS-ge4ne]

@@friendlyneighborhoodimmuno7192 but our immune system does if we contract covid and recover, which the vast majority will/have done.

[@arymhansie]

@@gardenvariety- Very true-a client's friend died two days ago,double vaccinated with the Pfizer and died in the hospital.