Vitamin D Receptor Resistance with Dr. Sanja Tamburic ND

Dr. Rade interviews Dr. Sanja Tamburic, an expert in the field of vitamin D receptor resistance, autoimmune disease and complex chronic illness. They discuss all of these topics in depth, and more!
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[@museitup4741]

great convo, i learned a lot

[@Dobrusska]

Great topic. I have few questions on this. So increased PTH levels with normal vit d levels are the way to diagnose vid D resistance. What about scenarios where PTH is elevated for diferent reasons while vit is normal? In the presence of autoimmune, why not suplement high dose vit D anyway? Also woukd genetic VLDR mutations predispose to issue. Lastly why would vit D cause flare in chronic patients? Could it be possible vit D lowering blood calcium increases circ oxylates thus symptoms?

[@halifaxnaturopathicdoctor6227]

Great questions, as always - video reply is forthcoming :)

[@yumounana]

Hi there! Around 4:30, you mention parathyroid hormone being at a "good ratio" with vitmain d level - what would you suggest might be an ideal PTH to vitamin d level? for example, I am well over 150 ng/ml (max number my test goes to), yet my PTH is 33. I would personally have expected PTH to be lower for such a high vitamin d level, so my thinking is this indicates vit d resistance. Would love to hear your thoughts.

[@halifaxnaturopathicdoctor6227]

video reply is on the way!

[@yumounana]

@@halifaxnaturopathicdoctor6227 Can't wait, thank you so much!!

[@viktorandre8545]

Hi, could high dose of vitamin D3 work for mast cell activation as well?

[@suzanneshort72]

Wondering as well if supplementing with K2 helps to counter potential increases in calcium levels?

[@halifaxnaturopathicdoctor6227]

Dr. T has told me it doesn't really matter. I had the same thought as you...but she's the expert!

[@1966MrAlex]

Could it be NAFLD (non-alcoholic fatty liver disease) which make the vit D resistance?

[@halifaxnaturopathicdoctor6227]

good question. I haven't heard of this link. What mechanism of action do you think might link the two?

[@denisesales619]

I have Mast Cell Activation and Ive been taking 10.000 UI vitamin D dose daily for a year and my PTH level increased and calcium decreased, maybe a higher dose would be better.

[@halifaxnaturopathicdoctor6227]

Interesting. I'm posting a video regarding this later today or tomorrow.

[@suzanneshort72]

Wondering if a genetic variant like I have might contribute to this issue / be an indicator for trialing the protocol despite having a 'normal' lab level? Quoting from Dr Rhonda Patrick's analysis of my 23andMe data - "The variant form (T) of the rs7041 polymorphism is thought to result in a protein that binds less efficiently to vitamin D. The (G;T) genotype may increase the risk of Vit D deficiency."

[@earthlastdaybiblechannel]

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