Watch SALT destroy BLOOD CELLS under the microscope

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Microbehunter

Microbehunter

Күн бұрын

We'll be using a microscope to explore the effects of osmosis on red blood cells (erythrocytes). You'll see how adding salt water and distilled water to a sample of blood affects the shape of the red blood cells and learn about the role of osmosis in this process. [video 187]
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Пікірлер: 316
@MrSorbias
@MrSorbias 3 жыл бұрын
Next time you do this, you don't need to hit so deep in your finger. As a diabetic, I do holes to my fingers very often, but never that deep. Thanks for the video :D
@caligirlsns
@caligirlsns 3 жыл бұрын
Use the side of finger less nerve action!
@Diksha_Gauns
@Diksha_Gauns 2 жыл бұрын
Yo don't make holes, you prick it.
@Mutantcy1992
@Mutantcy1992 2 жыл бұрын
@@Diksha_Gauns so if I can see through it, I've gone too far?
@Diksha_Gauns
@Diksha_Gauns 2 жыл бұрын
@@Mutantcy1992 hahahaha yes
@Mutantcy1992
@Mutantcy1992 2 жыл бұрын
@@Diksha_Gauns tysm :)
@daytonwhite9507
@daytonwhite9507 3 жыл бұрын
To me, these videos about the different methods and techniques are the most important. The average person that picks up a microscope wouldn't be able to see half of these images if not for this kind of information. Thanks so much oliver!
@chipmonk477
@chipmonk477 2 жыл бұрын
Microbiology is so incredible.
@pandakso3365
@pandakso3365 3 жыл бұрын
So cool to see the blood cells speeding along with moving water when you add the salt water!
@adu6115
@adu6115 3 жыл бұрын
These videos are very helpful, keep it up
@Mpower20188
@Mpower20188 3 жыл бұрын
Beautiful video, watching those blood cells flowing was almost hypnotic.
@DanielHKhalid
@DanielHKhalid 9 ай бұрын
This was a very interesting analysis. Thank you for sharing and for the self sacrifice of course in the process.
@AndreiIvanescuOficial
@AndreiIvanescuOficial 2 жыл бұрын
The most detailed blood cells ever in KZbin
@MarkC1685
@MarkC1685 2 жыл бұрын
It's a great video but i think it would be nice to put down the maginification used somewhere in the corner. This would give an idea what kind of microscope one needs to be able to do that at home if at all.
@motherearth1147
@motherearth1147 2 жыл бұрын
Nice videos, and very informative. What kind of microscope are you using? If possible model and name please.👍👍👍
@easankatir
@easankatir 2 жыл бұрын
Thank you for looking at blood. Hope to see more. Fascinating!
@adu6115
@adu6115 3 жыл бұрын
You should try baker's yeast under microscope
@RawTaste
@RawTaste 2 жыл бұрын
Hell no
@andrub23
@andrub23 3 жыл бұрын
Would you ever consider blood cells or human cells in the presence of fluoride? There are very old videos of this I remember from years ago.
@mariebossard1640
@mariebossard1640 2 жыл бұрын
Thank you so much. I just discovered your channel and this is exactly what I was looking for! Instructive AND fun! What magnification are you using for this, please?
@Microbehunter
@Microbehunter 2 жыл бұрын
the maximum was a 60x objective. And some digital zooming as well.
@danielchen9841
@danielchen9841 Жыл бұрын
one more question what cause the blood flow under microscope?
@perspectivism2006
@perspectivism2006 3 жыл бұрын
Great video, it was cool seeing blood cells coagulating microscopically. Do you think a fluorescence microscope would have made the blood cells more visible in the distilled water test?
@Microbehunter
@Microbehunter 3 жыл бұрын
Fluorescence microscopy would work, but one would have to add fluorescent antibodies (which bind against the red blood cell) to make them visible. So while it would work, I think that the time and effort would be high.
@perspectivism2006
@perspectivism2006 3 жыл бұрын
@@Microbehunter Ahh I see. Thank you!
@apologeticswithvladimir
@apologeticswithvladimir 3 жыл бұрын
very informative, thank you
@vivek7shirke
@vivek7shirke 3 жыл бұрын
Amazing, I'm a microbiology major and we just learned about haemagglutination. So this was very helpful
@jeetadhvaryu5680
@jeetadhvaryu5680 3 жыл бұрын
Same bro what r u doing currently?
@vivek7shirke
@vivek7shirke 3 жыл бұрын
@@jeetadhvaryu5680 Bsc in Microbiology
@jeetadhvaryu5680
@jeetadhvaryu5680 2 жыл бұрын
@@vivek7shirke best of luck for future
@vivek7shirke
@vivek7shirke 2 жыл бұрын
@@jeetadhvaryu5680 thanks. All the best to you too.
@minidwarfdude9230
@minidwarfdude9230 2 жыл бұрын
I had a lab session today on white blood counts and had to prick our fingers and determine whether we had a normal distribution of the types of white blood cells in our blood, got worried coz a lot of my blood was stacked but this video has eased my worries a bit lol
@tamlynburleigh9267
@tamlynburleigh9267 2 жыл бұрын
By inference, if we eat some very salty food, does that reduce the ability of blood cells to carry oxygen, which in turn can lead to cramp?
@rberdan1
@rberdan1 3 жыл бұрын
It would be nice if you mentioned the microscopy technique you used it looks like either DIC or oblique lighting. What type of lighting or microscope technique was used.
@aseaofbluewaves2510
@aseaofbluewaves2510 2 жыл бұрын
!ABSOLUTELY fascinating!! Favorite video!!
@jyotirani8232
@jyotirani8232 2 жыл бұрын
really interesting.
@atlas_yt5360
@atlas_yt5360 3 жыл бұрын
Finally a new video!!
@marias.5682
@marias.5682 2 жыл бұрын
May I ask you if you are jabbed? Could you please look at unjabbed blood and jabbed blood with one dose, 2 dosis, after 3 dosis. Thank you.
@woodstockxx
@woodstockxx 2 жыл бұрын
Forbidden..you’re banned !! 😂😂
@devd5899
@devd5899 2 жыл бұрын
Show us what Snake Venom does to blood in Microscope
@0Eliza0
@0Eliza0 2 жыл бұрын
snake venom is used in neuroscience (well...technically things like alphabungaro toxin with radio labeling agents that glow) to see the nerve activity... fun nerd fact...lol
@fxvlad
@fxvlad 2 жыл бұрын
Could you pls answer what model of a microscope you're using?
@bhavnigupta4456
@bhavnigupta4456 3 жыл бұрын
Wow. I got alot knowledge by this!!
@ronmartin7253
@ronmartin7253 Жыл бұрын
the variation in the shaping of the cell was profound. it wasn't mentioned but the NaCl spiking the membrane versus the expansion seen with the denatured water just has to be important. and likely still misunderstood or currently misrepresented
@rafiya7686
@rafiya7686 7 ай бұрын
Hello, I’m in 6th grade, I’m eleven, had an osmosis worksheet to submit and this helped a lot, I was absent the day my class was learning about this stuff, thx soooo much
@jburnett8152
@jburnett8152 2 жыл бұрын
Very interesting. Can I ask if you got the vase line ?
@AshVol-wz8rb
@AshVol-wz8rb Жыл бұрын
Every day, a little erudition, thanks microbehunter. Pretty cool.
@danfoster3613
@danfoster3613 2 жыл бұрын
I am learning so much from your videos and I'm seeing amazing things with my microscope!!!... So when I look at blood through my microscope there are many TINY particles buzzing around the red blood cells in the fluid. They look like gnats zipping around, in and out of focus. What are those? Some can be seen in your video here.
@gingerlygirl8415
@gingerlygirl8415 2 жыл бұрын
They look like wings
@csn583
@csn583 9 ай бұрын
Just got my first microscope (JttMicrocosmos) today and of course immediately pricked my finger! Thanks for helping me better understand what I was looking at. I came back after ~4hrs and couldn't find any remnant of my RBCs. Either I was doing something wrong or they all popped and went homogenous. Still learning the very basics, like noticing I can focus on at least 3 planes. (Cover slip top, sample, back of slide?) Anyway, just the beginning, next up creek water, and playing with stains. Lots of slide prep technique to master.
@jeremyd2453
@jeremyd2453 3 ай бұрын
I just got my first microscope today as well and did the same thing, and saw nothing at all. Have you figured out why this happened?
@kimberlykopetseg5154
@kimberlykopetseg5154 11 ай бұрын
It would be great to show a blood sample taken prior to your experiment then test the pH of the water you plan to use, for example; distilled water (does not contain minerals) is supposed to be alkaline but I tested one from the store and to my surprise it was very acidic, then drink a glass of water or so and after 30-45 minutes afterwards check another blood sample for comparison.
@jacobsimpson347
@jacobsimpson347 3 жыл бұрын
Love the videos
@rainfreed4316
@rainfreed4316 11 ай бұрын
Thanks this is really fascinating.
@oblamarise
@oblamarise Жыл бұрын
Please which magnification did you use
@Burrito384
@Burrito384 2 жыл бұрын
What magnification are you using to see this?
@LetsGo-LoveYourself
@LetsGo-LoveYourself Жыл бұрын
Very cool!
@davidcruz5605
@davidcruz5605 2 жыл бұрын
Try now with someone with the doublexhot on it, please!!
@20Days20
@20Days20 2 жыл бұрын
Thank you ❤️
@nikkion2140
@nikkion2140 2 жыл бұрын
What was the concentration of salt water you used?
@NavinF
@NavinF 11 ай бұрын
1:20 oof. You can put that lancet in a spring loaded lancing device and adjust the depth stop so it's more consistent than stabbing manually lol
@nikkion2140
@nikkion2140 2 жыл бұрын
Also, it would be a good idea to see the effect of adding water on blood sample not pre-exposed to salt water?
@rrrimve
@rrrimve 2 жыл бұрын
@5:47 do you know that Saline is salt solution that is a first thing being given to patients at emergency? Doctors leave direct supply of Saline a.k.a. mixture of salt and water, 0.9 percent sodium chloride (salt).
@romascopa8461
@romascopa8461 3 жыл бұрын
They use dark field for Lyme diagnosis now. Kinda crazy to see the spirochetes in the blood
@0Eliza0
@0Eliza0 2 жыл бұрын
OH my goodness...
@winnerbytes5898
@winnerbytes5898 3 жыл бұрын
Those very tiny dots in between the red blood cells at about 2 minutes must be the platelets right?
@fragstja3231
@fragstja3231 3 жыл бұрын
At 2:02 on the bottom right you can see platelets stacked up together which is how healthy platelets should be like.
@jmcd21182
@jmcd21182 6 ай бұрын
What zoom is this?
@oceangreen5322
@oceangreen5322 2 жыл бұрын
Thanks! Yor videos are interesting! But Why you don't recommend to purchase some microscopes for us? Such like slowmoguys do..
@Tschij
@Tschij 2 жыл бұрын
WoooooooooooooooOooooooooooooW, der Hammer! Danke für's Teilen! 👍 👍 👍 👍 👍
@ruhsaan-vevo7951
@ruhsaan-vevo7951 3 жыл бұрын
I love this guy
@asmolbean9300
@asmolbean9300 3 жыл бұрын
You can get autoretracting spring loaded lancets, it's much easier
@rochelledouglassmceathron511
@rochelledouglassmceathron511 3 жыл бұрын
What are those small white dots that are attacking the red blood cells
@pash9956
@pash9956 2 жыл бұрын
You must have an amazing microscope.
@Hoya144
@Hoya144 3 жыл бұрын
Hey, I'm a biology student in Belgium and I am very interested in buying a microscope! I know I'll be using the microscope frequently in the future. I watched a lot of your videos and I am very interested in the white monocular microcope you showed in a few of your older videos, the BMS Breukhoven. I am looking for a monocular microscope with a mechanical stage, light intensity regulator and a condenser. All your monocular recommendations on Amazon don't have all of these things... Can you give me advide on where or how I can get this microscope or where i can find one that is similar? Or should I go with a binocular microscope even though i prefer a monocular?
@Microbehunter
@Microbehunter 3 жыл бұрын
Why do you prefer monocular? Do not confuse binocular microscopes with stereo microscopes. They are different.
@Hoya144
@Hoya144 3 жыл бұрын
@@Microbehunter thank you for answering! I prefer monocular because I find it a little bit easier looking through it, the weight and because it’s cheaper. But like I said, I don’t mind purchasing a binocular if you can’t recommend me a monocular that has the things I want! And am really looking for a compound microscope, not a stereo.
@Microbehunter
@Microbehunter 3 жыл бұрын
Many microscopes these days are sold binocular, but especially for schools monocular are preferred (cheaper, lighter to carry). There are not many quality monocular compound microscopes available. Those that are, usually do not have a mechanical stage, no condenser etc. But I can give you a recommendation. Contact the company Euromex in the Netherlands. They have a microscope called BioBlue, which is monocular. We bought it for school. Watch the review video here: kzbin.info/www/bejne/qJyVnIx9rchshtk There is a second Dutch company (www.breukhoven.nl/) they used to make the BMS microscope that your referred to. They too have a range of good educational microscopes. I would contact either Breukhoven or Euromex (Email) especially because you live in Belgium (ideally you could visit them to have a look at the microscopes, but this might be difficult these days).
@Hoya144
@Hoya144 3 жыл бұрын
@@Microbehunter Thank you so much!! This really helped me a lot. Have a lovely day, thanks!
@anweshamandal957
@anweshamandal957 3 жыл бұрын
Can you isolate some blood from patients of sickle cell anemia, really anticipating to see the rbc
@asmolbean9300
@asmolbean9300 3 жыл бұрын
That would be very interesting, I imagine you can buy pre prepared slide specimens
@sandysandy967
@sandysandy967 2 жыл бұрын
I want to see the changes in the blood samples when any poison or any snake poison is added. How the blood thickeking will takes place and how it will stop to fflow.
@msisabelgomez
@msisabelgomez Жыл бұрын
Great idea.
@sandysandy967
@sandysandy967 Жыл бұрын
@@msisabelgomez its not idea as its truth.
@msisabelgomez
@msisabelgomez Жыл бұрын
@sandysandy967 I meant that I would like to see it too. This is because it's being introduced into many unknowingly.
@sandysandy967
@sandysandy967 Жыл бұрын
@@msisabelgomez I will attach some link plz watch those videos. It takes few min to tranfer from liquid blood to thik cloth of blood. This happen same in the human body and the flow of oxygen through blood stops. Victim can die by heartattack or by breathing deficiency.
@sandysandy967
@sandysandy967 Жыл бұрын
@@msisabelgomez kzbin.info/www/bejne/mX-7dWRmYtdph6c
@GamingWithZeap
@GamingWithZeap Жыл бұрын
i could look at bloodcells all day so amazing
@garsox
@garsox Жыл бұрын
Hi .. i might of missed it, but do we know the concentration of salt? and is it just saline or does it contain things like calcium or other constituents other than salt...asking for a friend
@jolexiajoestar
@jolexiajoestar 9 ай бұрын
bro does some pretty hardcore stuff in the name of science
@kikoface9984
@kikoface9984 2 жыл бұрын
Fascinating
@Dexters.LaBOREatory
@Dexters.LaBOREatory 2 жыл бұрын
What would happen if you mix my rh negative blood cells with an rh positive blood cells on a slide?
@matteodekrinis1222
@matteodekrinis1222 2 жыл бұрын
Nice
@lraewintercorn1516
@lraewintercorn1516 8 ай бұрын
what are the stationary things the cells are going around, hydrogels
@s888r
@s888r 2 жыл бұрын
Him: (pokes his finger with needle) Me: Closes one eye, clench my teeth, making weird faces 😉+😬+🥴 = My face
@jayanthjv
@jayanthjv 2 жыл бұрын
yess
@luismario4767
@luismario4767 2 жыл бұрын
What magnifications is it?
@copisetic1104
@copisetic1104 2 жыл бұрын
Take a blood sample and look at it then photograph the slide. Then take your shoes off and walk around on the grass or dirt and take another sample and photograph that slide. Most people will have clumping of the red blood cells, after 30-40 minutes walking or sitting with your feet connected to the earth without shoes on. You will notice the blood cells are no longer clumping but are separate.
@KoushikDas-zl1od
@KoushikDas-zl1od 2 жыл бұрын
I think so it's very pain full and taking out blood is difficult as I tried 5 times my skin wrinkled and came out in small pieces but blood didn't came
@newdimension2012
@newdimension2012 2 жыл бұрын
Can you do a video of this with Hydrogen Peroxide? Maybe 3% and 35%. Liked&Subed!
@sf3486
@sf3486 2 жыл бұрын
Can you view the blood of people that have had the V and explain what you see versus un-jabbed?
@woodstockxx
@woodstockxx 2 жыл бұрын
Forbidden..you’re banned !! 😂😂
@Jojo-in1wx
@Jojo-in1wx Жыл бұрын
@Kod so sorry…hope he’s better now and has some ivermectin or mms to help
@Jojo-in1wx
@Jojo-in1wx Жыл бұрын
@Kod that’s great news….I don’t know what it’s going to take to have the majority of others understand what just happened.
@abdulkadirabdirasak3644
@abdulkadirabdirasak3644 3 жыл бұрын
Blurry dots that not move are watery?
@14xx07
@14xx07 2 жыл бұрын
Wait.. why are they stacked? 🙈 Btw, am gonna head over to the channel on the hardwares!! :D sound super interesting!
@0Eliza0
@0Eliza0 2 жыл бұрын
Interestingly, EMF in even the slightest doses for an hour at a computer causes stacking...I watched an old video from the 80s when people were warning about it and then bought "Invisible Rainbow" - I think perhaps we are either shortening our life span or (hopefully) we are just hunky dory with all this stacked blood from various external, uncontrolled things such as medicine and our cell phones.
@UniverseOfDrama
@UniverseOfDrama 3 жыл бұрын
Plz make a video on how one can see white blood cells(WBCs) and platelets
@Microbehunter
@Microbehunter 3 жыл бұрын
The video on white blood cells is finished and will be published in the next few days!
@lorirode-off763
@lorirode-off763 2 жыл бұрын
Ooo, can hardly wait!
@RolfLunheim
@RolfLunheim 3 жыл бұрын
Maybe it would be an idea to add some sodium citrate (or EDTA) to prevent coagulation?
@abdulkadirabdirasak3644
@abdulkadirabdirasak3644 3 жыл бұрын
Sir, I'm from Somali i watched much more about your KZbin on microscopic suggestions, and learned many topics how setting up the microscopic, by the way, i wanna buy a new microscopic so, which one will you recommend me to buy. Though i dont want microscopic with camer, but i wanna microscopic with out camera. Pls help me with issue.
@TheoPantazi
@TheoPantazi Жыл бұрын
2:29 can someone tell me what the other things around the blood cells are please. They're much smaller than the cells of course, and they appear to be twitching, almost like they have a head and tail structure in some cases.
@seandmaccormack.8528
@seandmaccormack.8528 2 жыл бұрын
If we were all taught this in school we wouldn’t be sick be able to read our destination.
@UC-Love
@UC-Love 2 жыл бұрын
What a beauty.
@orbitalheaven8368
@orbitalheaven8368 3 жыл бұрын
Hey so I was wondering where was the white blood cells
@kimberlykopetseg5154
@kimberlykopetseg5154 11 ай бұрын
You could do another test drinking salt water and try different salts at different times (table salt, sea salt, etc.). Another day using tap water, another day ground your feet on grass/dirt after walking around in the house, sidewalks etc. not connected to earth and do comparison slides.
@thatsdaniellelol
@thatsdaniellelol 3 жыл бұрын
This is just amazing!
@tomaskns
@tomaskns Жыл бұрын
Next time please examine Nematomorpha!!
@edlesivertsen3375
@edlesivertsen3375 3 жыл бұрын
Check blood with and without wifi on.....or before and after standing two minutts in front of your smart meter........would be interesting...
@rohanofelvenpower5566
@rohanofelvenpower5566 2 жыл бұрын
that's dead blood though since its outside. It doesn't have chi circulating through it anymore.
@jhbrown53
@jhbrown53 2 жыл бұрын
Will you do vaxed blood vs unvaxed blood?
@godhateseveryonewhodoesntr5977
@godhateseveryonewhodoesntr5977 2 жыл бұрын
What do you expect to discover? This comment section is full with this request.
@rickkey4226
@rickkey4226 2 жыл бұрын
Wow! You’ve discovered osmosis!
@kiddoquit
@kiddoquit 3 жыл бұрын
Is a microscope with a magnification range between x40 and x900 usable or is it just a toy? Thanks!
@Microbehunter
@Microbehunter 3 жыл бұрын
The magnification does not say anything about if it is a toy or not. The magnification is the same, but toy microscopes will give you a blurry image even though the magnification is the same.
@kiddoquit
@kiddoquit 3 жыл бұрын
@@Microbehunter Understood, thank you very much!
@robertbolding4182
@robertbolding4182 2 жыл бұрын
they dont stack during clotting they stack because of zwitter ion charge ,
@shreyasss9047
@shreyasss9047 3 жыл бұрын
Try to add some acetone. It causes hemolysis
@janami-dharmam
@janami-dharmam 2 жыл бұрын
Plain water can do it; it will swell up and break - the membrane will not be visible. Salt water will cause the cell to shrink; center will depress first and it will look more like a donut.
@shreyasss9047
@shreyasss9047 2 жыл бұрын
@@janami-dharmam Normal Red cells are not osmotically fragile. They swell up but they will not break easily. Acetone directly dissloves the membrane and cause hemolysis
@siccmade_3604
@siccmade_3604 2 жыл бұрын
Pause the video at 00:42, look at it from a good distance like 3 feet. Wait 30 seconds then press play.
@inifin8
@inifin8 Жыл бұрын
What happens when you introduce iv fluid in the blood
@rutujasonawane4002
@rutujasonawane4002 2 жыл бұрын
Can we observe this under 100x or 40x microscope.
@danielchen9841
@danielchen9841 Жыл бұрын
hello dear i like u chanel a lot, if u can show\test whats happen to white blood cells as well red blood cell under diffrent type of test like: 1.whats when happen we\u drink 2-3 glasses of distiled water? 2.whats when happen after we\u drink 2-3 glasses of spring water? 3.whats happen after we\u drink 2-3 glasses distilled water mixed with 5 drop hydrogen peroxide ? i drank net distiled water i produced myself for 2 years and mixed it with hp with a protocol i seen at big groop at fce book but i couldnt never test how it influence the blood cells as well as other cell if u can figure out any clever test ill aprichiate that very much. thanks in addvance.
@VANOXmicroscopy
@VANOXmicroscopy 3 жыл бұрын
Great video :) I will have to take a closer look at white blood cells. They move like amoebas :O
@originsdecoded3508
@originsdecoded3508 Жыл бұрын
Would using any other water like bottled or tap water would have had any difference in the results of the blood cells? I think not, I think regardless of what water you use, as long as you are introducing large amount of water they will always do this to the cells. Thats how people die in real life from over water consumption in where they get puffy, the organs fail, and then drown internally basically.
@midnightxuser6447
@midnightxuser6447 2 жыл бұрын
Sir prick the side and then you won’t have sore finger later. Can you do another vid &show what is a reticulocyte & how do they affect the blood &how do they tell information about different types of anemia and organ damage from anemia. Love yer show !🔬🩸
@BrainNbeautyMalaysia
@BrainNbeautyMalaysia 2 жыл бұрын
Hi.. what the cases if all the blood cells sticking together? Regards.. HANI
@Microbehunter
@Microbehunter 2 жыл бұрын
They stick together when the blood dries up under the microscope
@kattakaraca3894
@kattakaraca3894 3 жыл бұрын
Why do we get salt water injection in hospitals in stress situation s, it is dangerous than would cause thrombosis, the opposite of what they tell us? Or am I wrong?
@Agatheos
@Agatheos 2 жыл бұрын
What is the formation called, when the blood cells stock up? I can't understand it
@Microbehunter
@Microbehunter 2 жыл бұрын
It is called Rouleaux formation. It is a normal process that occurs because the larger surface area of the flat red blood cells allows them to stick together.
@Agatheos
@Agatheos 2 жыл бұрын
@@Microbehunter Thank you very much!
@dragonspaw.blogspot4461
@dragonspaw.blogspot4461 Жыл бұрын
How long does it take for blood to start stacking, if anyone knows. TY!
@Microbehunter
@Microbehunter Жыл бұрын
depends on the amount of blood that you put on the slide and how fast it dries. Sometimes stacking starts first at the edge, where evaporation is faster. I could see stacking several minutes after making the slide.
@kamalakrsna
@kamalakrsna 3 жыл бұрын
diatomatious earth amazing geometric sight
@jamdigital9530
@jamdigital9530 2 жыл бұрын
At 2:36 there are some small things wiggling around.. what are these?
@godhateseveryonewhodoesntr5977
@godhateseveryonewhodoesntr5977 2 жыл бұрын
It's probably some platelets.
I bumped my head and put the blood under the microscope
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