Webinar12-From GWAS to gene:What are the essential analyses and how to bring them together using HSR

Webinar #12 - From GWAS to gene: what are the essential analyses and how do we bring them together using heterogeneous stock rats?
Presented by
Abraham A. Palmer, Ph.D.
Professor & Vice Chair for Basic Research
Department of Psychiatry
University of California San Diego
Goals of this webinar:
Heterogeneous stock (HS) rats are an outbred population that was created in 1984 by intercrossing 8 inbred strains. The Center for GWAS in Outbred Rats (www.ratgenes.org) has developed a suite of analysis tools for analyzing genome-wide association studies (GWAS) in HS rats
Explain the HS rat population and their history
Describe the automated pipeline that performs GWAS in HS rats
Explore the fine mapping of associated regions and explain the various secondary analyses that we use to prioritize genes within associated intervals