Weekly Research Update for April 20, 2024

00:00 Introduction and the usual bad Dad Joke
01:17 Adult ADHD and Risk for Lewy Body Disease and Dimension
05:50 Association of ASD and ADHD with Cerebral Palsy in Children
08:22 Randomized trial of chiropractic treatment for children with ADHD
Research Discussed in the Video
Adult Attention Deficit-Hyperactivity Disorder is associated with Lewy body disease and cognitive impairment. A prospective cohort study with 15-year follow-up.
Á Golimstok, MJG Basalo, M Majul, W Berrios… - The American Journal of …, 2024
doi.org/10.1016/j.jagp.2024.0...
Association of cerebral palsy with autism spectrum disorder and attention-deficit/hyperactivity disorder in children: a large-scale nationwide population-based study
Q Chen, M Chen, W Bao, L Strathearn, X Zang, L Meng… - BMJ Paediatrics Open, 2024
bmjpaedsopen.bmj.com/content/...
The effects of chiropractic adjustment on inattention, hyperactivity, and impulsivity in children with attention deficit hyperactivity disorder: A pilot RCT
I AMJAD, IK Niazi, N Kumari, J Duehr, G Shahzad… - Frontiers in Psychology
www.frontiersin.org/journals/...
Research Not Discussed in the Video
Intervention with comorbidities encompassing Attention Deficit Hyperactivity Disorder (ADHD), Bipolar Disorder and Borderline Personality Disorder (BPD): A Case …
SR Barve, G Kadam - Journal of the Indian Academy of Applied Psychology, 2024
Enhanced ADHD detection: Frequency information embedded in a visual-language framework
R Hu, K Zhu, Z Hou, R Wang, F Liu - Displays, 2024
Understanding the Heterogeneity of Neurodevelopmental Disorders and Its Implications: An Exploration of Repetitive Behaviors
DQ Beversdorf - Biological Psychiatry: Cognitive Neuroscience and …, 2024
Current Complexities in Establishing Risk Factors for Attention-Deficit/Hyperactivity Disorder in Longitudinal Research
KN Thompson - Biological Psychiatry, 2024
The socioeconomic burden of adult attention-deficit/hyperactivity disorder in Spain
M Merino, P Maravilla-Herrera, TM Lorenzo, JA Arance… - Global and Regional Health …, 2024
Revisiting the Relative Contribution of Common and Rare Genetic Variants to Attention-Deficit/Hyperactivity Disorder Among Diverse Populations
Y Dai, BS Fernandes, Z Zhao - Biological Psychiatry, 2024
[HTML] Telephone-Assisted Self-Help for Caregivers of Adolescents with Attention-Deficit/Hyperactivity Disorder: An Observational Proof-of-Concept Study
C Dose, T Roschmann, C Kinnen, C Rademacher… - Journal of Child and Family …, 2024
The Comparison of Mind wandering and Cognitive distortions in Attention-deficit hyperactivity disorder Adults with and without Pornography
S Nasrollahi Valojerdi, A Abolghasemi, R Soltani Shal - Journal of Applied …, 2024
… and Commitment Therapy on Emotion Regulation, Behavioral Symptoms, and Academic Performance of Children with Attention Deficit/Hyperactivity Disorder
SK Hosseini, RJ Fard, MT Shoushtari - Journal of Clinical Research in Paramedical …, 2024
Attention-deficit hyperactivity disorder symptoms and brain morphology: Addressing potential selection bias with inverse probability weighting
A Dijkzeul, H Tiemeier, RL Muetzel, JA Labrecque - Human brain mapping, 2024
Effects of an online mindfulness-based program for parents of children with Attention Deficit/Hyperactivity Disorder: A pilot, mixed methods study
HH Lo, J Lam, ZJ Zhang, M Cheung, SKC Chan… - Frontiers in Psychiatry
Coping strategies in mothers of children with autism and attention deficit hyperactivity disorder: latent profile analysis
C Berenguer, A Pardo, E Rosa, S Gómez… - International Journal of …, 2024
People with Epilepsy (PWE) and Attention Deficit Hyperactive Disorder (ADHD)/Attention Deficit Disorder (ADD)(P4-1.001)
SM Owais, F Asghar, H Pervez, S Saleem, S Naz… - Neurology, 2024
Costs associated with adverse events during treatment episodes for adult attention-deficit/hyperactivity disorder
J Schein, M Cloutier, R Bungay, M Gauthier-Loiselle… - Journal of Medical …, 2024
The Correlation between Novice Psychopaths, Time Management, and False Feelings in Metacognition: The Mediating Role of Impulsive Behaviors
M Hosseinimotlagh, H Rashidi, F Abolfazli, A Akbari - International Journal of …, 2024

[@Indiekid-1976]

Please please make a video about the current worldwide medication shortages!

[@supermum2kids233]

I understand that 'Lewy Body disease' was what Robin Williams suffering with at the time of his passing!

[@nobody8328]

It wouldn't surprise me at all to learn that bouncy brain of his was ADHD!

[@Chimpy_Mc_Gibbon]

I can't understand why chiropractors are legal. They are blatantly lying at best and irresponsible and dangerous at their worst. A lot of my patients visit them for a variety of reasons and they are all under the impression that they are medically trained. It's awful.

[@anxiousArtisan]

Not all of them are liars, but it does have a weird aura around it where some chiropractors are really out there claiming they can cure anything and everything, it's really ridiculous. On the other hand, if you go to a chiropractor for chiropractor stuff, they can be incredibly helpful - a single treatment from one took my sciatica pain from "crying while putting on my pants" to almost nothing. A couple of treatments and changing my desk ergonomics at work wiped it out entirely.

[@RoSa-kr8hy]

In the dementia study, “Patients who had been previously treated with medications for their ADHD for more than 6 months or were taking such medications at the time of baseline examination were not included.” In the earlier study we saw that increased risk of dementia was not seen when adults with ADHD were treated with stimulant medication. This makes me think that untreated ADHD is the more concerning risk factor. It reminds me of how untreated hearing loss increases risk of dementia. Treating conditions like hearing loss and ADHD seems to mitigate their potential risks.

[@publius9350]

I noticed the same thing. Plus was unsure if unmedicated prior due to late diagnosis or prior diagnosis, but without medication pursued. Generally, the Israeli study from earlier makes me wonder about stimulants as preventatives - in that study people with ADHD were threefold likely to get dementia, but if they had been treated with stimulants for the ADHD that increase of risk was negated. Seems like this study did not look into that specifically, but man, I am hoping someone is currently. Different countries have a lot of different protocols for treatment or lack of in cases of ADHD, with variations in medications available as well.

[@plantemor]

Glad you had a good time, and that dad joke was adorable! Also, dementia terrifies me haha.

[@executivelifehacks6747]

I suspect ADHD-related lack of sleep is a causal factor for dementia risk. Certainly I struggle with getting sufficient sleep, and that seems to relate to brain fog etc. One needs sleep to maintain the brain in good health.

[@mifasof]

live it up dr. barkley

[@publius9350]

The Israeli study that showed ADHD patients having threefold risk of dementia showed the increased risk being negated if they had been taking methylphenidate. From what you are saying, it sounds like the first study you mentioned (LBD) did not address what treatment plans were pursued prior to development of LBD and/or dementia, but I certainly would be interested in knowing. Hoping these potential benefits of medications are being investigated and not just the risks.

[@jonr6680]

I never took DrB for a beer guy, but authentic Bavarian beer must be pretty special, especially at the cultural source. Envious! Did the 10 crates clear customs? Next episode !

[@denisehiggins9966]

Thank you for keeping us current with the research. Are there reliable developments in neuroscience for electronic or pharmacological solutions for Lewy Body Disease or dementia?

[@DTXResearch]

While not surprised they didn’t find a between groups effect - they seem underpowered, so had no chance of finding one unless it was very large (quite unlikely). So we can’t conclude much from an underpowered study.

[@kasia199213]

Awww Moosey had something important to add for sure

[@andymellor9056]

The pasta Dad joke was utter Farfolly. 😉

[@erickmendieta6857]

Dr. Barkley thank you so much for your videos!. All my family have ADHD and we struggle a lot with histamines and allergies. I wonder if allergies can cause neuroinflammation or problems with the vague nerve, and these increase ADHD symptoms. Thank you so much in advance for your answer. Here are some research that can explain some of the symptoms I mentioned: Cholinergic Urticaria: Subtype Classification and Clinical Approach Transcutaneous vagus nerve stimulation in patients with attention-deficit/hyperactivity disorder: A viable option?

[@jennyportelli]

I would love to hear a video on object impermanence and theory of mind relating to adhd.

[@drrodopszin]

With these "possibilities" does any type of treatment help against the development of these, or we just sit back after the diagnosis and wait to see which axe would fall?

[@chrispasson1940]

My friend's mum was diagnosed with Lewy Body Disease at the age of 99 when she first entered a live-in facility when my friend needed oncology surgery.

[@Deviliza]

"Lets not her to excited.." 😆 Don't worry, I'm not sure excitement is the feeling I get thinking that my risk for Lewy Body is perhaps very much higher than others.

[@cjsun7871]

All I'm saying is that I have always loved to have scalp massages. I feel like they just hit me differently than other people. Tonight, ironically, I was doing that to my daughter because she's had a rough week, well months at school. (Struggling with what I'm thinking is ADHD. Me, my sister, my parents, her dad possibly, her dad's brother all have ADHD.) I'm going to see how her day was tomorrow when she comes home from school. She loves scalp massages.

[@Patricia-vd9xh]

Bavarian Beer ! Fabulous. love Germany. 😀

[@nancysdsk]

👏👏 I am looking forward to your next presentation.

[@arcanethievery]

The flickering mirror image of the loft ventilator on that black surface between you good professor and the sculpture made it hard to watch the video and listen to you at the same time. Was it intentional? :D

[@greadion4]

Could the higher rate of diagnosis of ADHD among people with cerebral palsy be related to less opportunity to engage in cognitively demanding tasks?

[@Herfinnur]

I had to take a break after that dad joke

[@42MOL42]

Your activities are approved, jealus 😂 well deserved though.......we appreciate you

[@martawieczorek5862]

I've never heard of chiropratic before so I googled it. The founder D. D. Palmer said he "received chiropractic from the other world" from a deceased medical physician named Dr. Jim Atkinson 😂😂😂 Also fantastic dad joke!

[@annabackman3028]

If you play with a bunch of Russell's Viper (Daboia russelii) I don't think your first name matters. Poisonous. Very poisonous. Never trust a snake. Swedish proverb: Let wolf savage wolf, and the lambs will go in peace.

[@nymphecho777]

Hello, what are your thoughts on dyslexia?

[@flor.7797]

Obviously

[@flower-jp1om]

As a foreigner of English, what does An impasta means?

[@BXLrules]

it's imposter, written out as in speech.

[@kowe76]

😂😂😂😂 dad joke

[@A_Lex]

Looks like first comment

[@42MOL42]

I really wonder how the Germans cope or German people with ADHD cope, I love my German friends, but they 100% don't cope if something isn't on time to the second 😂