Wegovy and The Pancreas

[@Aviation_Professional]

I monitor 5 patients on semaglutide and all have top of the range or elevated Lipase (3 or 4 being elevated). We are titrating the dose to use the least effecetive dose as infrequently as possible. Pancreas possibly inflammed from the GLP-1 drug

[@AlejandroSanchez-tq9qx]

Took wegovy for 3 month and started having sharp pain under my rib on my left side ask tge doc to check my pancreas I did have inflammation 5 months later still get the pain

[@pamhlaing2662]

Probably the best explanation on this... I have been looking around the net for a while... Thank you

[@theofficialdrdan]

Glad it was helpful!

[@SM-ml6hs]

Hi doctor thank you for the video. I have had pancreatitis related to high triglycerides over 7 years ago and have been on fenofibrate to lower my levels. Can i go on wegovy safely?

[@ibewlopezlopez9341]

Please help with this question...I had acute pancreatitis 5yrs ago can I use ozempic now for weight loss...I've had no problems with my pancreas sence..

[@thomaslavoie1]

Great video! 10/10!

[@alp6244]

How does a GLP-1 med help with insulin resistance?

[@Brian.8272]

will the price of these medications start to go down in price at some point? id like to try tirzapitide

[@HelloMalaka]

I have two boxes of wegovy, have gallstones and terrified of starting it due to the possibility of developing more gallstones leading to pancreatitis. 😩😭😭😭😭

[@theofficialdrdan]

Continue to follow up with your doctor. The risk is exceedingly low.

[@lilygarcia5668]

I got on Depo Provera and gained a bunch of weight,so now Im on a semiglutide and am having bad stomach pain. No fever or anything just stomach pain.Is stomach pain a side effect?

[@theofficialdrdan]

Can be. Follow up with your doc

[@cs1487]

Can semaglutide help PEI? 9:40

[@RichAnderson114]

I'm a 43 year old power lifter who discovered that I have diabetes when I had a stroke in October. I think I would be a good candidate because I do resistance training like it is my religion but my doctor is shy to prescribe this to me becuase I had a pancreatic attack that hospitalized me five years ago. Ive since had one severe attack but didn't go to the hospital. If I lose 30lbs that will put me at 270lbs and 20% body fat.

[@theofficialdrdan]

That is a tough call. Really depends what caused the attack initially. I'd ask to maybe see a specialist for review!

[@RichAnderson114]

@theofficialdrdan Thank you for the response. The hospital really didn't give me any answers unfortunately. They just told me to eat less fat and sugar. As I wrote, my dietitian and GP are reluctant to put me on this... I booked my first available appointment with my endocrinologist January 2025.

[@Brian.8272]

my doctor took me off semaglutide for a few months because my liver and pancreatic enzymes were slightly elevated, he wants to see if they go down before putting me back on, i originally lost 40 pounds from semaglutide and i have gained back about 15 pounds, i would like to try tirzapetide but its expensive

[@begevt]

How long to lose the 40 pounds?

[@margaretcalafut5092]

Do you mean Saxenda?

[@Brian.8272]

@@margaretcalafut5092 no, semaglutide

[@Brian.8272]

@@begevt dont remember exactly, i think about 6 months maybe a little less

[@Dragonfly_vbz]

Same issue

[@christelpecoraro2915]

I have been on semaglutide for about 10 months and lost 40 pounds and wanted to lose more but my lipase levels were 394. Can this be reversed and i could go back on?

[@theofficialdrdan]

It is possible with lower doses or a break. But it also poses the question whether you are symptomatic or not. It's know these drugs can raise lipase levels but that doesn't necessarily translate to pancreatitis

[@Honey-Bee-25]

​​​@@theofficialdrdan have they found out why it raises lipase levels? Is it making you burn glucose more effectively & keeping insulin low, thereby increasing lipase levels in the blood or something? Kind of like when someone is losing or burning fat rapidly through fasting or a large calorie restriction and has elevated cholesterol because fats are mobilizing & being released in the bloodstream to burn? So cholesterol normally reads higher until it balances out. For example, my cholesterol is always elevated when I get labs if Im regularly intermittent fasting more than 16hours, even if I'm eating healthy, because I assume I'm burning fats. So, I'm assuming it's kind of the same thing happening with the lipase levels since the medicine helps you burn glucose more effectively & keeps insulin low. Just wondering if that's what's going on, and of you are not symptomatic, it's not a cause for concern with the lipase levels, and is just something to keep an eye on? Or should someone actually take a break from the medication if levels are elevated?

[@retrobitestvrbtv1852]

If you have had pancreatitis does that mean the wegovy injections are a no go ?

[@theofficialdrdan]

Depends on the cause and other factors.