What Fruit Flies Taught Us About Human Biology

[@Master_Therion]

Thomas Hunt Morgan: Fruit flies. Isaac Newton: No, fruit falls. Stupid apple hit me on the head.

[@nathanberrigan9839]

Time flies like an arrow. Fruit flies like a banana.

[@24emerald]

I ask my stupid son what did he learn in college. He said, "Pie are square" ... stupid boy! ... "how many times I got to tell you, pie are round!" ... "pie are round!"

[@zizo0ditto1989]

@@nathanberrigan9839 ah, I see you are a man of culture as well.

[@Biociety]

Slightly hungry: Eat the apple 🍎🍏

[@OtakuUnitedStudio]

@@milesparker3114 May to drag a joke out into the street, stomp its face into the curb, and shoot it 16 times in the back ganglands style.

[@Sorcerers_Apprentice]

We bred fruit flies in my genetics class to see how traits like eye color were passed down. But the flies they gave us were really inbred to begin with, so when we mated brothers and sisters, we saw all kinds of messed up deformities like flies with curly antenna and wings so crumpled they couldn't fly. One group got a bunch of fruit flies with legs growing out where their eyes should have been.

[@OtakuUnitedStudio]

Holy crap.

[@vinaynagashetti]

Thank you for your service to Evil Science. Hope you make your LegInEyeInator soon. 😆

[@xterramichigan]

Ok that’s interesting af tho I wish our bio class got mutations

[@DoeSwiftandBond]

Poor things.

[@zackpumpkinhead8882]

Real Cronenbirds

[@jehmarxx]

There are flies around my fruit bowl. Me: "Thank you." Me after that: *brings out fly swatter*

[@pierrecurie]

I don't know of any fly swatter with small enough holes to hit fruit flies. Those bugs are small enough to fit in the holes.

[@SilverGreeneye]

Me: “I will express my gratitude by giving you a ten-second head start.” Fruit flies: *not understanding English*

[@kellydalstok8900]

@@pierrecurie Electric fly shatters work best.

[@Biociety]

In Horticultural land, fruit flies considered pest. In Gene Experiment, fruit flies is so beneficial to increase understanding of gene and it's influence to the organism, including human.

[@intergalacticspace6897]

something that seems useless is might be very useful

[@fruityautism]

I use them as compost is that good?

[@patldennis]

Do fruit flies act as pollinators in any capacity? Don't they only attack fruit as it's alreasy well on it's way to decay, thus not a primary pest?

[@Varizen87]

Years ago, I had a professor at Western Kentucky University, Dr. Jeffery Marcus, who studied at Cambridge. And said his Fruit Flies were from the direct original stock of Thomas Hunt Morgan. Dr. Marcus left long ago though and last I heard he went to a school up in Canada. Was an especially depressed and miserable guy. Told us never to ask him how he was doing because his last good day had been 15 years prior.

[@ShanniBananni]

This comment reads like a Morgan Freeman monologue. 😊

[@I-am-stevo]

@@ShanniBananni had another go at reading it with a Morgan freeman voice, it's far more enjoyable. Maybe I should imagine Morgan freeman reads everything to me? 🤔

[@ShanniBananni]

@@I-am-stevo 😁😁😁 great idea.

[@Helveteshit]

Doubt any resemblance to the original stock is null when they've reproduced over 7 decades. Due their quick turn-over rate and reproduction. Their evolutionary traits shift a lot faster too. Which is why, insects sometimes survives better to changes in their environment than other creatures. Because they have such a turn-over rate, they accumulate more changes to their environments faster and the stronger genes that fit better in that environment, quickly solidifies.

[@Varizen87]

@@Helveteshit it’s more about the legacy and prestige of it. Morgan’s didn’t have some of the eye colors like vermillion and emerald that are in the modern stock. Keep in mind those flies are not naturally evolving or changing. They control their breeding carefully. You knock them out with ether which you have to be careful with lest you sterilize one with too much, you use tweezers to look at them under a microscope for sex, and then pop them in test tubes with fetid bananas depending on what you want to breed. These flies are not natural in any way. You can see a lot f the differences between wild ones and lab stock even without a microscope. Dr. Marcus had so many different eye colors in his stalk which was something he used to track genes. Keep in mind this was like 2007 too.

[@chriscostello117]

I just had a generation spanning war with fruitflies over the summer...what have i done......

[@herewasbob7650]

Why we need sleep? Sleep is the best part of my day.

[@PabloSanchez-qu6ib]

You woke me up to tell me that!?

[@bluesap7318]

Sleep is for the weak

[@PabloSanchez-qu6ib]

@@bluesap7318 That is true. I can sleep a week and it's a good thing because when I wake up in start making puns.

[@FizzySugarStar]

Indeed now I must be off to sleep

[@Some_Guy77]

Lol, what's sleep?

[@thesilentone4024]

Walks into the kitchen sees fruit flys oh thank you so very much then walks over grabs a fly swoter then proceeds to thank them as he is murdering them all

[@JTManuel]

These flies are a mainstay in my genetics courses back in my undergraduate biology days back in college.

[@robinhahnsopran]

We're heading out of the mullet phase of covid hair and into the pre-Fabio, swoop-swoop phase, I see, and I am here for it. All of these are the technical terms.

[@jamesharmer9293]

I saw an old video of Micheal's from about a year ago last night. He was practically unrecognisable! Since I can't grow hair like that any more, I'm getting jealous...

[@Torsee]

I sense attraction...

[@expertexcavatinginc]

HAVE YOU SEEN CONAN'S? YASSSSS

[@randomanimations1621]

@@Torsee hmm

[@combatking0]

DNA is said to be made of "letters". So if I were to rearrange the DNA of fruit flies, I could invent the world's most musical snacks, the fluit fries. I could even win a Nobel flies. I'll buzz off now.

[@joeydr1497]

I’m surprised they didn’t just breed the weirdest fly possible

[@DFloyd84]

Some biologist figured out how the fruit fly's genome codes for legs and altered one to have extra legs growing out of its eyes.

[@WouldntULikeToKnow.]

@@DFloyd84 poor little dude

[@davidmacphee3549]

If you can make one as big as a rat in a box you can use him to scare all the Girls. LOL

[@jakobraahauge7299]

Please do some videos on some of these studies! The sleep studies seem very interesting! Like - why am I binging SciShow instead of sleeping?

[@autumn.redhawke]

Also, I love my fruit flies in the summer. They know who gets the jam out of the fridge for them. Lol

[@davidmacphee3549]

I put some jam on a sticky pad for mice. Bye Bye flies.

[@TheaSvendsen]

Hey, I saw a documentary about exactly this! But I still learned a lot of new things, which is probably because you guys at SciShow somehow always make all topics both entertaining and easy to understand - also never feels like it’s been dumbed down :-)

[@l1ghtd3m0n3]

I mean, if only 1% of our genes differentiate us individually, it makes sense that we’d have more genetically in common with what appears radically different from us.

[@하람배-q5k]

no? it still makes more sense that things that are similar to us are more genetically similar too. edit: unless you just meant knowing that would make it not unlikely.? then I don't get what you mean by "more".

[@DoeSwiftandBond]

These animals are precious, want to have families and fufilling lives. I like to respect them and treat their habitats gently.

[@thomashughes_teh]

In a world where flying cars are obsolete, humans grow wings and wingless insects the size of house cats follow us home to our houses carved from gigantic pumpkins.

[@tammymccaslin4787]

I’d read that trilogy.

[@twocvbloke]

Build my own neural network? Aside from the one already in my head? Nah, too much work, I have computer things to fix... :P

[@kidslearningwithsethuandsa9593]

Very Useful Thank you so much

[@troyclayton]

Cool video. Whenever I think about fruit flies I think eosin eyes. I always though it would be a great song title.

[@coffeepot3123]

I love fruit flies tbh, they represent the actions of my inaction of keeping my place habitable. But now i view them as funny little beings zooming past my face in silence.

[@Smokescale]

This is so cool, all the somewhat (if not outright) accidental discoveries made through breeding fruit flies. Also, rockin' that fabulous Markiplier hairstyle!!

[@akumaking1]

Can you cover the mad genetics of Bdelloids?

[@ekstrajohn]

Still rockin' the Covid hairstyle eh?

[@jessicaevans7847]

Hey, the mullet took like a decade to die.

[@jeffreym68]

They helped me learn how to sequence DNA.

[@mr.k7457]

My buddy's mom works with fruit fly neurology

[@mrwaldoful]

another great episode

[@gaurisreenidhi]

they're called Cinderella of the genetic world, and yes, I always thank them when I see them :)

[@Rastitute97]

Awesome video😊 could you do a video like this on the zebrafish? They're the animal model for my PhD thesis and people (in my country anyways) downplay their legitimacy as an animal model

[@nicoleonfeels]

I immediately wanted to grab my apple cider vinegar after reading the title 🤭

[@arielanonymous7270]

Exactly whose killing fruit flies with a swatter

[@TheDoctorAndALobster]

Michael lookin good ! hair looks dope !

[@kimbratton9620]

I absolutely love scishow!!

[@anirbanmaitra6051]

Very helpful

[@omnigeddon]

My fruit flies have evolved to me lol.. and eventually either evolved or mixed with houseflys.. now I see them staring at me all day as a super long winged fruit flies... and when I walk sometimes they come up to me saying "hi" lol... one of them even lived since october of last year by hibernating.. I'm like "no way that fly is still alive.. it's been since October.. this was last month. "April 2022".. it would wake up.. look around and went back to hibernation..

[@firulamry]

Is it me or his voice sound really similar to Jake from vsauce3

[@RustyTube]

3:25 - Fruit flies have notches in their wings. But lots of other animals have it, including mammals like us. We have wings? Why have I not been told this earlier?! I have trouble walking so wings might prove helpful to me. 😃😃😃😃😃😃😃

[@minnymouse4753]

Did you know DNA test from the main star child skull has 200 coherent base pares with significant matches to any know genome not even fruit flies .and the DNA test that debunks the skull comes from a peace of bone that happened to be found next to it. And didn't fit in the first place

[@garethferguson4434]

“DNA testing in 1999 at BOLD (Bureau of Legal Dentistry), a forensic DNA lab in Vancouver, British Columbia, found standard X and Y chromosomes in two samples taken from the skull. Novella considers this "conclusive evidence" that the child was both male and human, and that both of his parents must have been human in order for each to have contributed one of the human sex chromosomes.”

[@garethferguson4434]

“Further DNA testing in 2003 at Trace Genetics, which specializes in extracting DNA from ancient samples, isolated mitochondrial DNA from both recovered skulls. The child belongs to haplogroup C. Since mitochondrial DNA is inherited exclusively from the mother, it makes it possible to trace the offspring's maternal lineage. The DNA test therefore confirmed that the child's mother was a Haplogroup C human female. However, the adult female found with the child belonged to haplogroup A. Both haplotypes are characteristic Native American haplogroups, but the different haplogroup for each skull indicates that the adult female was not the child's mother.”

[@minnymouse4753]

@@garethferguson4434 i said the debunking comes a piece of bone that happened to found next to

[@FilthyGaijin]

Thomas Morgan really do be looking like a Chad meme IRL

[@redeye118]

First time I've heard "the 2010s". Makes you think

[@FelipeKana1]

"Usually" men. That's kinda of an understatement, no? Like, how often they aren't?

[@pierreabbat6157]

There's a mutation called AIS, itself on the X chromosome, which results in an XY person being phenotypically female.

[@xKumei]

Time flies like an arrow. Fruit flies like...a banana.

[@rosepetals8181]

😂👍🤭

[@OrnisApiens]

Those fruit flies have gone on to be part of something amazing, while the ones I've got try to swim for the Olympics in my coffeepot. /lh

[@autumn.redhawke]

Sometimes listen to scishow while im working and don't see who is talking but I can still tell who it is.

[@massimookissed1023]

I can tell which of my six cats is meowing at me just by their voice.

[@autumn.redhawke]

@@massimookissed1023 Helps if I hit the right button to like your comment.

[@massimookissed1023]

@@autumn.redhawke , I swear KZbin shrank the area you have to hit to do a thumbs-up. Sometimes i start and have to cancel a comment 4 times before I finally get that magic thumb location.

[@johnnystir9796]

I could listen to Michael Aranda read the phone book.

[@beretperson]

How can they only have 4 chromosome pairs but share 60% of our genome?

[@alfredsutton7233]

Don’t ask stupid questions! Nothing to see here. Move along quietly.

[@harrysher9468]

im foing research!

[@fadiashush7286]

I love your videos, if only you could make them a little, just a little longer, so you could speak a little slower. I'm not a native speaker which makes it harder for me to follow😅

[@earlofdoncaster5018]

Yeah, click on the cog button to select playback speed. Also captions are available.

[@AryadiSubagio]

The first time I heard his name, I thought Michael was telling a story about a guy named Thomas who hunt another guy called Morgan

[@darkangelprincess101]

if you pause it at 1:27 he looks like he is in the middle of a violent sneeze. I didn't pause it here on purpose

[@deepsy2k]

Suddenly the movie "The Fly" makes more sense

[@MrRickyw01]

To think that I helped with my brother's experiment using fruit fly eye color for sex determination 50 years ago... who would have thought how useful they can be?

[@boulderbash19700209]

For me personally, reading about fruit flies in highschool was finally made me understood Darwin theory of evolution. Before that, I could not grasp the difference with Lamarck theory of evolution and why Darwin was right instead of Lamarck.

[@ash7324]

My boi getting thicc

[@chickenman7032]

That they are annoying in your house in the summer lol

[@OdinMagnus]

I like how vegans go crazy when you tell them about how animal testing is important and then you tell them that fruit flies are part of the testing. =D

[@culwin]

I like how people are so upset that some people are vegans. Easily triggered by what other people do :D

[@bmsg1]

@@culwin I like how people are so upset that some people hate vegans. Easily triggered by what other people do.

[@qwaqwa1960]

Take THAT, Sarah effin' Palin.

[@DonFaro]

Plot twist: We are the fruit flies to Aliens

[@Jade-g6p]

I also think people would be angry if we used primates for things that hadn’t been tested in any other organism yet.

[@Jop_pop]

I always knew Minecraft could only have been developed by fruit flies

[@edenschwenk4649]

2:17 as a trans person, thank you so much for acknowledging us!

[@yanlopez674]

What? Howwww

[@MadMorgie6318]

@@yanlopez674 it described XY folk as 'usually men', which says not all XY folk are men, just most. A nice acknowledgement, is all.

[@yanlopez674]

@@MadMorgie6318 Oh, I thought it was something else oks

[@MadMorgie6318]

@@yanlopez674 For all I know, Eden might have been referring to something else, but that is what I, myself, noticed.

[@edenschwenk4649]

@@MadMorgie6318 yeah that's it!

[@Rubrickety]

You forgot to mention that Notch is also responsible for creating Minecraft.

[@kamiboy]

TLDW: did they teach us that fruits make a delicious treat?

[@raizo-ftw]

Reading that makes you wanna watch instead lol

[@gijbuis]

I would be interested to know how a demented Fruit Flie behaves

[@hdezn26]

If it's demented it maybe is planning world domination... But problem with that is cat is already doing that plan...

[@MagicalToothpaste]

All this and we don't know why we sleep

[@bartoluszek7111]

I’m surprised that there aren’t already some vegans screaming FRIUT FLIES LIVES MATTER

[@jimlovesgina]

The meat industry causes about as much green-house-gas emissions as automobiles. Maybe you think global warming is a myth? Why would any vegan give a rat's ass about fruit flies?

[@davidmacphee3549]

Results of fruit fly testing in zero gravity may reveal if we can breed safely on the moon or Mars.

[@gab.lab.martins]

2:17 colour-blind people won't be able to understand the graphics about them.

[@jondoe4807]

Michael looking Sleezy and greasy with that hair 🤣

[@poksnee]

Time flies like an arrow; fruit flies like a banana.

[@aarusty51]

They should put them near a 5g transmitter to see what would happen. It would be simple to see and record.

[@massimookissed1023]

Some 5G wavelengths may be short enough to have an effect, maybe just a bit of heating. Cody'sLab had *_had_* a video of house flies in a microwave oven being totally unharmed as that wavelength was much longer than the flies. KZbin thinks microwaving flies is a suspendable offence, but killing hundreds of mice with weird antique mousetraps is just fine(!)

[@Connerhasamassivethang23]

My friend mutated a big noise fly and what the fly did was drink water that his inhaler sprayed onto and now the fly might be able to live 5 years and it looks like a kid on 100mg of caffeine

[@joshuaadams8240]

Hey what did you do? Discovered the double helix. Hey what did you do? Studied fruit flies. And the Novel Prize goes to......

[@ouiVEVO]

They use zebra fish for the same reason!

[@pierreabbat6157]

Nonsensical unit combination: morgan per sturt. Alfred Sturtevant, for whom the sturt is named, was Morgan's student.

[@patldennis]

Calvin Brideges is my favorite Morgan protégé. Apparently he really enjoyed (cue Bill Burr voice) the LaDeees!

[@boogerrag6437]

am i part fly?

[@kanadezosGT]

You fly AF bro

[@hdezn26]

Everybody is a fly . . . . Untill they hit the ground.

[@hdezn26]

@Eastern fence Lizard I remember that movie somewhat . . but forgot the name of it . . .

[@hdezn26]

@Eastern fence Lizard Sounds about right , Been years since I've seen that movie though.

[@stax6092]

I actually don't kill fruit flies. Usually by the time they show up, the fruit isn't good enough to eat anyways. That or they show up 'cause the banana peels in the green cart. House flies though, I hunt 'em every single time.

[@huldu]

Once we get rid of sleep we'll be so much more productive and can finally work 18 hour shifts. Not sure what anyone would do during those remaining 6 hours so we might instead just have 23 hour work shifts and one hour breaks.

[@stvie3]

i droso-feel-ya buddy

[@ber2996]

Want a nobel prize? Get up and start studying fruit flies!

[@contrarianduude3463]

Being named after your food source doesn't sound right.

[@Bildgesmythe]

Fry guy, burger boy, wonton woman. ..doesn't work for humans.

[@therealstewyward]

I thought Inside Out showed us why sleep was needed though... 🤔

[@killmimes]

Easy to genetically modify! Did we learn nothing from the movie SPECIES?

[@OtakuUnitedStudio]

I learned how to make a "horror" movie not very scary, and how to rip off H.R. Giger's style.

[@G1Main]

Taught me about apple cider vinegar!! Ahaha. All my real ones know..

[@Soniboy84]

So the moral of the story is that we're fruit flies.

[@LostMekkaSoft]

"This one is called Notch, because researchers found it while playing Minecraft."

[@TheodoreManthovani]

Well, dorsophila having 60%ish genes similar to humans aren't shocking. Saying they be having 5% genes similar to humans, now that would be shocking.

[@hoangtrunganh]

What Fruit Flies Taught Us? Hestagon is bestagon

[@K9TheFirst1]

"People with XY Chromosomes" "People with two X Chromosomes." Sooo.... Men and Women?

[@simonebebe4621]

Who likes chicken nuggets with sweet and sour source

[@boogerrag6437]

are we all part fruit fly?

[@chesh1rek1tten]

We have a lot in common with bananas, too. So if you take your hand and an equal weight of banana, mush them both into a paste, the paste has more DNA in common with a banana than it does with a human

[@CzarRobberFly]

Fun fact: what he is calling fruit are actually vinegar flies

[@alexgewecke9576]

Why swat them? They are harmless. Just get them outside somewhere.

[@GumOnTheWall]

michaels hair @_@

[@allertonoff4]

Hypercool !

[@DanielSantanaBjj]

I was told by a college professor that there’s no such thing as male and female so the eye color thing is not true 😂

[@justsomepersononyoutube9271]

I went to jail almost fuckin died

[@jonrau5988]

I still don't like them but at least now I know they've useful.

[@Saujas]

Fruit flies are best orgaism for study of genetics. 🤘✌️

[@del-chicken2641]

The diabetic fly...