Which Molecule is the Most Cursed? (Cursed Lore)

[@S3RL]

Hell yeah, I love being part of this!

[@rushoffman2364]

#1 crossover I never thought I would see

[@roberttran1114]

banger

[@yeethappymeta]

no fucking way, I never expected this in a million years. nice work!

[@adamantris2]

no way your music is featured one of that chemist's videos. youre probably one of the last people i expected here and im all for it!

[@lilyp4369]

so happy to see one of my favorite musicians ever to get some love in a chemistry channel lmao

[@RamiSlicer]

I like when That Chemist said "It's Chemistrin' Time" and Chemistried all over the place

[@Thekingofgodofwar]

Who you gonna chemicall

[@jackingwads7513]

Boo get off the stage

[@Smelron3317]

Did you turn chemical into a verb

[@Oracle13]

Drink that sweet ( ( ( c h e m t e a ) ) ) 🧬 ☕

[@Jokke13th]

That's one cursed word

[@joshuagoodsell9330]

My non-chemist friends would be embarrassed for me about how excited I was when you said you'd use 3D models of molecules 😂

[@AmethystMoon444]

Whoever you hired as an editor or if you did this yourself...FANTASTIC. SO GOOD. keep it up!!!!!

[@That_Chemist]

David - he is incredible

[@reformlabs1050]

Thanks :D I do appreciate the appreciation XD

[@elitearbor]

@@reformlabs1050 Keep rocking on, man. You're doing a great job, seriously!

[@reformlabs1050]

@@elitearbor Appreciate it, thanks!

[@kitsunefox2023]

@@reformlabs1050 I appreciate that you appreciate our appreciation.

[@ShowMe7.]

the 3d models are so intuitive to people like me who arent huge into chemistry but still wanna watch chemistry videos, i love when theyre added into pretty much any chem videos so thank you!

[@jeffstaples347]

The highlighted area reeeeeeeeeeeeeeeeeally helps me.

[@That_Chemist]

awesome :D

[@GogiRegion]

Even as someone into chemistry, some of them surprise me.

[@bitterlemonboy]

The skeletal formula are actually easier to read

[@ElementalAer]

Easier to read, but the 3D models really show how "cursed" the molecules look irl

[@panqueque445]

My little contribution for the compeelation: I don't know why, but I never noticed any asparagus-like smell in my pee. But I remember this one time I was peeing, looked down and saw the bowl was red. I had a mini heart attack thinking I was peeing blood, until I remembered I'd eaten beetroots for lunch.

[@frtzkng]

IIRC the asparagus thing also has a genetic component. Some can eat asparagus just fine, while others produce compounds that would violate the chemical weapons convention

[@lapisinfernalis9052]

@@frtzkng Isn't that the same with broccoli? I know someone who turns into a weapon when he eats broccoli, but I am completely fine.

[@jailbrekartz]

@@lapisinfernalis9052 Yes, it is! I know I have the genes for both and it absoluteley REEKS. I love asparagus (it is german cuisine after all), but I can't stand the smell afterwards. It's terrible. I have some work stories involving asparagus, involving me almost getting sick from the smell, even though I am pretty resiliant against smells.

[@lapisinfernalis9052]

@@jailbrekartz I am German myself and I never noticed anything after eating asparagus or broccoli. So I may be lucky. But not with my nose. I smell EVERYTHING. You would think that this is great when you are a chemist like me, but it is also a curse. Especially when the fridge you have to take your stuff out reeks of vomit, rotten cabbage, fish and something uncomfortably sweet even when you are standing 2m away from it. And everyone else seems not to smell a thing.....

[@jailbrekartz]

@@lapisinfernalis9052 I have a bad nose and don't smell much at all. It's usually the stuff that reeks that I smell the most, but it's kinda a godsend for my work (nurse). We can swap our genes, wenn du willst!

[@dingusdan9983]

Back in my high school biology class we were talking about genetic traits such as hitchhiker's thumb and attached earlobes. In some groupwork, I started talking to my teacher about some other genetic traits and asparagus pee smell came up. When we got back to the lecture, my teacher brought up asparagus pee and asked the class who can smell it. I proudly raised my hand up high, but as I looked around the classroom, nobody else was raising their hands and were just staring at me.

[@FirstLast-oe2jm]

Oh I actually have a piss chemistry story! So dog piss, according to my vets report, should have ~4 times the nitrogen as human piss. So I tried to refine dog urea into nitric acid. My neighborhood still doesn't know "the month of 'That Smell'" was me. the nitric acid was shitty and barely worked. I do not make nitrogen from piss any more.

[@That_Chemist]

Oh no!

[@dragonridertechnologies]

I really hope this one gets featured. It's amazingly cursed for such a short story. Hopefully none of your neighbors watch this, or recognize you, though!

[@pedrovargas2181]

This deserves a spot on That Chemist's "Chempilations". 🤣🤣

[@Youtuber69428]

Hey uh bro, how did you get the piss? Just wait behind your dog?

[@TheMightyOmega-NotTheAlpha]

Not an asparagus pee story, but a lab pee story: Lo these many years ago, when I was the most junior chemistry faculty member at my institution, I was assigned to teach a pre-med general chemistry lab section. We had a weekly meeting about that week’s experiment with the program director. When we got up to pH and buffers, we did (and still do) a pretty standard pH meter titration and buffer stuff. And then she says “the urinalysis strips and specimen cups are in the big storage cabinet in the back of the lab.” Well, the last activity in the lab was that the students collected a urine specimen and did a urinalysis using clinical dip sticks and then did some calculations based on their own results. The director had them bring the damned specimen cups back to the lab to do the analysis, and the bathroom was on the other end of the building, so they were walking down this long hallway past the Dean’s Office with cups full of pee. As I got more seniority, I changed it to extra credit and put the urinalysis strips and chart into the bathroom, and when our case of strips ran out, I discontinued it the whole thing. Bonus: I saw some pretty nasty pee over the years. Some guy comes up to me and asks “what does it mean when the urinalysis chart shows ‘erythrocytes high’?” My answer: “you should probably go see an MD sooner rather than later.” His pee was red.

[@revenevan11]

I really love the highlighting of the parts of the molecules you're talking about! Very helpful for those of us who don't know all the vocab!

[@TCOphox]

I've known about 3M Novec in the server/PC cooling space. But I didn't know they were such cursed looking PFAs... It's like a christmas tree but the decor is just flourine atoms.

[@Matthew-cx9gj]

Fluornaments

[@dietrootbeer]

I never thought I would have a story worth a chempilation, but here is my asparagus piss story: During covid I moved to live with my aunt and uncle to take online classes while working on their farm. For about three months during this period, I ate asparagus for dinner EVERY SINGLE NIGHT. They were in season and came from a farm nearby so they were fantastic, however, I got so used to having asparagus piss that I stopped being able to smell it while urinating. Eventually, I moved back home and went out to a bar with my friends. This was about two weeks after I last ate asparagus and I went to the bathroom in this bar to pee, when the guy at the urinal next to me turned to me and said, "Damn dude, you got a bad case of asparagus piss." I didn't even know what to tell the guy. How could my pee still smell?! Anyway, I went out to tell my friends and now they still call me asparagus piss guy.

[@science_and_anonymous]

Short but funny story with pee, I remember working a lot with aromatic thiols in the lab, and one of the most notable side effects I noticed, even with the small amount of exposure I got, was that my urine smelled horribly of asparagus. It was pretty consistent, but still took me a long time to finally come to the conclusion to the source of the smell.

[@toyocolla]

The only thing I found cursed about Diminazene was how so closely symmetrical it is.. _IT WAS SO CLOSE!_

[@victordonchenko4837]

It'd likely tautomerize between the two arrangements -- so it is symmetric on some time scale, and its deprotonated form is symmetric!

[@toyocolla]

@@victordonchenko4837 Oh, nice!

[@Khemystriy]

Pee story: I once read somewhere that the body isn’t able to break down all citric acid when consumed in an “overdose”, in theory this would make your pee acidic. At an evening after some alcoholic beverages I decided to dissolve 6.0gr of citric acid in water and downed it. The day after I felt horrible with random bursts of pain high up my back which slowly spread to my bladder. Once I finally needed to pee, it was deep dark brown. Don’t be as stupid as me

[@jakethomas5016]

Bro why? What did you gain?

[@jackwastakenx2]

@@jakethomas5016 the forbidden knowledge

[@LucasBitcoinnaisseur]

Thank you for including 3M Novec 7700 in your video :D I noticed and commented on your video about PFAS that this molecule is one of the most cursed molecules ever. Made my day :)

[@That_Chemist]

Oh yeah, I remember! See I do read all the comments :P

[@ToadJimmy]

I love these molecule visuals! the 3d plus highlighting different molecule parts is super cool to see

[@bluestonecreeper720]

Now that I've completed chemistry 1, I understand half of what you're saying instead of none!

[@That_Chemist]

hooray :) keep up the good work!

[@chemdelic]

Absolute insane editing. Videos are getting better and better!

[@Tony-zi9qg]

i can't believe none of your cursed videos have featured Calicheamicin γ1 yet. it's got so many functional groups that i've never seen anywhere else before it's amazing. Esperamicin too.

[@julian4868]

I just looked those up and good lord I’ve never seen a molecule so massive. that is insane

[@milesmccollough5507]

actually, one of his other "cursed molecule" videos had calicheamicin in it. he said it was, quote, "GILDED in weird functional groups, there's something cursed everywhere you look," naming in particular the carbamate sidechain and the insane hanging trisulfide as well as the weird interrupted glycosidic chain with the aromatic iodine-subsituted ring.

[@Tony-zi9qg]

@@milesmccollough5507 really? Can you share the link? Im on mobile with little data 😅

[@cellina.starfire]

@@Tony-zi9qg kzbin.info/www/bejne/ooG5nYCVppx_ebs this is the one!

[@That_Chemist]

kzbin.info/www/bejne/ooG5nYCVppx_ebs

[@ZackFreedman]

Your videos are the only ones I click on sight. I'm digging the new pizzazz!

[@That_Chemist]

Thank you! Your recent 3D printed board game video was really cool - it makes me want to get a 3D printer eventually

[@workingsmile3836]

Now we need the opposite. The prettiest 3d molecules

[@lapisinfernalis9052]

Cursed molecule here: When I was doing my bachelor thesis in crystallography, I faced something quite cursed, at least for something in crystallography. 1. I thought that my brownish crystal had a tetragonal spacegroup. (Hint: it wasn't) 2. The data was meh, but still manageable. 3. It was heavily disordered. Imagine a Ag-atom, surrounded by 4 Ga (in tetrahedral formation) wich are connected to a Cp+++ ligand (Cp with 3 t-Bu groups at positions 1,2,4), where all the t-Bu groups are twisted differently. And the cherry on the ice: the counterion was a Ga-atom, with a Cp+++ ligand and 3 O3SCF3 groups. ALL WERE DISORDERED in MULTIPLE ways. It took ages and a bit of help from more experienced colleagues, to get to the conclusion that the crystal was a bad boy and it had actually a monoclinic spacegroup which by chance had the needed measurements for a tetragonal group (a=b=/=c, all angles 90°), but not the right symmetry elements. The thing was still horribly disordered. Fun fact: The crystal wasn't even the reaction product I had to analyse. It happened through an accident, because the guy who made it did assure us, that no radicals were involved. You guessed it. There were radicals inside the flask and when I opened it to take out a crytal, the whole thing intantly reacted as I touched it with a spatula.

[@_themonocle_]

Came for the chemistry, stayed for the desk

[@spanishSpaniard]

As a biochemistry student bisfosfoglycerate isn't remotely the most cursed chemistry biology can make. If you dislike your eyes look up what GTP cyclohydrolase I does. It opens two 5 membered rings, selectively oxidezes one carbon until it leaves in the form of formic acid and then it catalyzes the formation of a new membered ring with an amine and a ketone. Just look up the reaction.

[@jessicaiwanowski8946]

A little something for the chempeelation. My high school best friend told me that she always ate asparagus when on an ocean fishing trip with her dad. The asparagus pee attracts fish.

[@That_Chemist]

:(

[@crossg4434]

I don't have asparagus pee and when I do I have to eat a lot and it's not very strong at all like it used to be for me

[@jnelson4765]

Honestly most proteins look cursed to me but I never got beyond polymers in understanding organic chem.

[@Grateful.For.Everything]

The effort that goes into these videos does not go unnoticed, hell of a lot of work editing all this together for us 🙏🏼 we appreciate it!

[@That_Chemist]

thank you :)

[@lexinwonderland5741]

Okay dude, i have been dead inside lately, and that NileRed clip made me laugh audibly for the first time in probably a day or two. Great fuckin work as always Joey

[@Zadrakos]

Very late to the party but holy crap. I'm not a chemist at all, a good majority of your videos are gibberish to me, but I'm super interested in it, and I'm picking up things as I continue to watch your videos. I'm someone who does a good chunk of work in Blender and watching the end of the video, showing what you did in Blender honestly surprised me... a ton of work for a relatively small video / channel compared to others who have a similar quality in editing and such. Honestly, awesome work!

[@mpioman9885]

Thumbs up for S3RL at the end! But seriously those 3D molecules and the spinning tier list animation at the end are SICK! thanks for the amazing content.

[@neosynh8338]

biggest revelation of this video, that chemist likes happy hardcore and s3rl, so based.

[@That_Chemist]

I made a whole playlist for S3RL open.spotify.com/playlist/4CoX5Xj1WnPfbtXUJNqSHL?si=abe1d405d0014d2e

[@knightoftime8948]

one of the bathrooms in my high school smelled so much like piss, i could smell the ammonia. as for how i can discern the smell of ammonia from piss, i might've caught a whiff of very very concentrated ammonia gas from leaving it in a jar overnight for an indicator experiment. two fun facts! its hard to use red cabbage as an indicator for oxyclean, as the oxyclean will go clear after a few minutes. leaving red cabbage in ammonia makes it go from green to yellow, which means that when it turns yellow it's probably a good sign to open it in a well-ventilated area. do not smell concentrated ammonia gas, it will burn your nose(you will, however, be able to discern that oh so ungodly smell from just about anything, including bathrooms that smell like piss)

[@janronschke7525]

Have a nice asparagus story went to the factory toilet and just asked my kolleg wo was just finished, iv the asparagus soup was good and his bewildered"Where do you know that from" had me laughiung my ass off. Apperently not everyone can smell the vile...

[@tim-tim-timmy6571]

I was at university when I made the link between asparagus and my pee smelling funny. I was studying biochemistry. Apparently I am not always the sharpest tool in the shed.

[@GogiRegion]

If you do a pee themed compilation for some weird reason, do beets. It makes your pee and poop both bright red starting almost immediately after consumption. I’ve definitely had a few times where I thought I was bleeding because of that.

[@noyoucantsaythat]

From now on, I will require every single lady of the night I hire the services of to consume a plentiful plate of asparagus before our usual activity of mario kart and disappointment.

[@Karupin-and-chill]

Loving the new style and the smooth animations

[@27.minhquangvo76]

A while ago I posted a somewhat cursed homework assignment on your DIscord. The compound involved in the assignment was similar to that in 10:56, but what's even more cursed is that it involved a reduction of a diyne bonded to two carbinol groups to a tetraene.

[@lonewizardtv7225]

Love the visuals, I usually leave these on in the background but now they're FULLSCREEN 😎

[@That_Chemist]

Very based

[@Blakearmin]

Holy shit! You're up over 100k, now!? I remember when you had less than 10k and I said that I loved coming across great channels before that they blow up, and look at you now! Congratulations, man! This is awesome!

[@That_Chemist]

thank you :)!

[@everythingexplained3226]

12:40 I can just see it. The researchers looking at the structure. -Yo dat molecule look cursed AF. -You should put it in your eyes.

[@Mnnvint]

One of the fascinating things about That Chemist is that you can hear his smile.

[@That_Chemist]

on no *you can tell* 😳

[@adamgasth]

Cyclohexatriene should definitely be on the list. It’s just like benzene, but messed up

[@boltez6507]

what I leart early on is tha chemical molecules can't just be predicted,you just have to remember them

[@pharmboy9484]

I used to think asparagus pee was a myth. Asparagus was a fairly common vegetable as a child, and one of the few I'd eat regularly, just had to season it right. It wasn't until I was in my early 20s finishing my undergrad that I was given one of those genetic history kits as a birthday present. Apparently there's a genetic component to it, and nobody in my family had that issue, which may explain why none of us had a problem with asparagus.

[@That_Chemist]

Interesting

[@bigjay875]

Love the 3D models 👍

[@That_Chemist]

Thanks :)

[@frtzkng]

If you're wondering what a _bad therapeutic index_ is: the therapeutic index sets the doses needed for a pharmacological effect in relation to the toxic or lethal dose. Drugs with bad therapeutic index characteristics have the toxic dose threshold very near the pharmacologically active doses, or display a wide variation within individuals, e.g. a pharmaceutical dose for one may be toxic for someone else.

[@pr0hobo]

I love the style tho I just didn't feel that many of these where really all that cursed from a 3d point of view. maybe one or 2 where kinda cursed due to their 3d nature but the rest only got the higher ranks because of what functionally groups they had which isn't very interesting when we're debuting a 3d molecule tier list. now I know you've already done a bunch of cursed 3d structures before like cubane, helicene, propelane, and adamantane but I'm sure there are countless other structures and such that could benefit greatly from the 3d experience and would have made for a better first impression of this style. perhaps a rotaxane or knot molecule or an endofullerene, maybe even a hyperbolic [7]circulene or [8]circulene. Even if you've touched on some of these types before maybe you could still make a video in the future better demonstrating some of their 3d cursed geometry with this new style.

[@That_Chemist]

Yeah that’s a fair point

[@ComputingCactus]

asparagus pee to me smells like burning/boiling agar. When I was doing my bachelor's in bio labs if we were growing something on agar we used an inoculation loop (a little rod with a tiny wire loop on it), and to sterilize the loop after we'd heat it over a bunsen burner flame. To cool it we'd just shove the loop into another agar plate; it smelled rank and always reminded me of asparagus pee.

[@That_Chemist]

It does indeed smell bad when a hot loop hits agar

[@Thekingofgodofwar]

Is Grimace a 3D molecule?

[@Saltssaumure]

The outro music fills me with S3RLtonin :)

[@morgan0]

5:30 it would be cool to see a video on common metabolites that end up in urine which have a noticeable smell which aren’t a result of an infection or disease. mine occasionally smells like butter, which i’m guessing is butyric acid, but also rarely like celery seed and anise, which i’m guessing could be anethole but maybe is something else.

[@That_Chemist]

Urine has a spectrum, most certainly

[@koukouzee2923]

Its 3 am and iam glad i didnt go to bed

[@warlokyx]

I feel like there are two distinct groups of ppl that are into s3rl. Hardstyle ravers with a meth habit and chem majors 🤷‍♂️

[@Xnoob545]

I am neither I am the physics and math nerd that is also into linguistics and stuff and is a gamer who doesn't go outside and also secretly a weeb except i barely watch anime

[@DeathMetalDerf]

Wow!! The tier list software has really come a long way! The way you can point out specific bonds and display things in different colors is awesome!

[@That_Chemist]

We also are working on a more advanced model with accurate bond lengths and stuff, but that likely won’t be applied until we do a phys chem video

[@DeathMetalDerf]

@@That_Chemist I'm very much looking forward to seeing it!🤯

[@DJHLX3]

Peeing asparagus smell is one thing. Sometimes when I smoke cigarettes my urine smells like ciggarettees. I don't think that's a good thing.

[@That_Chemist]

💀

[@tachalorah]

A TC and Nigel collaboration would be legendary

[@That_Chemist]

Your ideas are welcome - I talk with Nigel on discord

[@muffinman3052]

@@That_Chemist gotta be something piss related. it would be funny or something

[@jerryguebard4518]

Lol the Hamilton Morris and Nile snippets are hilarious!

[@ManuDunno]

The production budget went up a bit, huh?

[@okboomer6201]

It's 10 pm, and I just climbed into bed.

[@hydrogenbond7303]

Mention of murexid reminded me of story with rhodamin B. It was during our organics seminar. Right before the end, we heard a loud bang. As we walked through the hallway a man with completely pink face and coat passed by. At the end of the hallway the lab door was open wide and also pink. As we peeked from distance, the whole lab was pink. Later we found out that the guy had the dye in separating funnel and of course didn't releave the pressure. As he continued shaking, the funnel got so pressurized It just blew and painted the whole lab pink. And other time someone else managed to get water in large can of LiAlH4...

[@jmowreader9555]

Everyone wants to see a "Things I Won't Work With" collaboration with Derek Lowe.

[@kaboom4679]

Unfortunately , he doesn't really seem to do a lot of these types of stories these days , or , the How Not To Do It ones . They are pure gold and the comments are pure platinum .

[@klikkolee]

I really appreciate the 3d models! There's often a lot about the shape of a molecule which isn't obvious from the 2d drawing

[@joeylawn36111]

Another Cursed molecule involving the urinary tract: Calcium Oxalate. 😮😟🤢

[@AmberLam.]

Wow the quality just jumped into S tier for this video. Nice improvements and clearly a ton of work went into this. 💪

[@That_Chemist]

Thanks Am :)

[@morefurless]

My addition to the pee video, I was skating a stair set and I went for a board slide on the rail my board slipped forwards and I sacked it completely, later that day I peed blood and omg it was the most painful injury in my life

[@pedroff_1]

Notvomly does "vir" atand for it being an antiviral, "buvir" means it works on that B Unit of the Hepatitis B viral replication

[@pedrovargas2181]

Rotating 3D models, highlighting specific groups in the 3D and 2D models... Damn, this is One. Step. Above. previous material. Congratulations. The final two minutes, even with mute I can barely read the screen.

[@jermainerace4156]

"...asparagus transforms my chamber-pot into a flask of perfume.” ~Marcel Proust Strangely enough I don't really mind the smell of asparagus pee. I love asparagus, and the smell of it's powerful pee it just reminds me that I should get more.

[@julian4868]

hey That Chemist, I know you’re not a biologist so I’ll forgive you this time, but for scientific names you only capitalize the first Latin word, like “Homo sapiens”. the first word is the genus and the second is the species. I don’t know exactly why it’s like this but it is

[@hempwick8203]

Dude you could do 7 videos a week, even 14 or 21 through multiple channels and I'd watch most of them all. Highlighting the carbon, as embarrassed as I am to admit it, taught me what carbon based lifeforms means.

[@Frieren_a_freira_defeituosa]

The most cursed is the orthocarbonic acid🌚

[@That_Chemist]

💀

[@elnombre91]

Azoxy compounds are known intermediates in nitro hydrogenations. As expected, they're bad and are one of the compounds to keep an eye out for (along with nitroso, hydroxylamine and azo compounds, all mutagens). You have to wonder why we use nitro hydrogenations in api synthesis.

[@ebony61899]

One time my doctor detected elevated levels of calcium in my urine so she ordered me to take home these two medium-sized jugs and fill them up with piss over the course of 48 hours and then deliver them to a lab so that they can be examined further. The kicker is that one of them had to be refrigerated and the other had to stay at room temperature, so I kept one jug of piss in the fridge that my entire family used, and then the other was safely stored in my bathroom. Never knew how bad pee could stink until it’s just been sitting in your bathroom for a day or two. The lady at the lab also didn’t seem thrilled to be handed two heavy jugs of pee either but then again who would be. Good news though, the pee came out with normal levels of everything except for a tiny bit of blood.

[@penteractgaming]

propellane, sea urchin borane clusters, boron centered nucleophiles, Zn2(C5(CH3)5)2, helicenes, mobius aromatic systems etc. cursed af molecules

[@JappeChristian]

After watching this video, I am going to stop calling myself "diabetic" and instead calling myself "Alloxan-immune".

[@Astella_GL]

Don't have a pee related story, but if you do end up doing a urine special, you should definitely call either a "Chem-piss-lation" or "Chem-pee-lation"

[@klikkolee]

I noticed that there were several times where a part of the molecule was highlighted, but the molecule wasn't in an orientation that made it very clear which part was highlighted. Often, you moved on to a different part of the molecule before the molecule rotated enough to get a clear view of what you were originally talking about.

[@ogonbio8145]

when i was about 8 years old I was standing in my backyard holding a cup. I suddenly felt the urge to pee, the stars aligned and i peed in the cup. It was surprisingly warm... and salty

[@berylman]

I thought Falcarindiol was especially interesting. A didn't think a di-ynes in a natural product much less a carrot would even be possible

[@GerinoMorn]

I always forget that I ate asparagus, and it goes through my body in under 20 minutes. It's always a mild shock in the bathroom xD

[@1marcelfilms]

Probably said it before but tetraethyllead has a really funny windmill shape

[@partlycloudy7707]

Could you do a tier list on antibiotics? Some of the structures are kinda cursed, and some of the antibiotics straddle the line between toxin and life saver, and some are straight toxic.

[@Aut0mati0n]

If you want to dip into eye drops again, Brimonidine and Dorzolamide (both glaucoma medications) are pretty cursed.

[@defenestrated23]

You are missing my favorite cursed 3d molecule: ascaridole. A plant-produced organic peroxide, like wat

[@BryanLu0]

The new format is very cool though I think slotting the chemicals into the list could use some work

[@reformlabs1050]

Hi, David here (guy who did the visuals), could you please elaborate a bit? I'm open to suggestions :)

[@BryanLu0]

@@reformlabs1050 I think it looks very stiff, maybe more easing?

[@reformlabs1050]

@@BryanLu0 Ohhh yeah, I get what you mean.. the interpolation was set to linear so it's a uniform velocity... It didn't slowly build up to speed and decelerate at the end

[@WickedPhase]

10:07 Not sure why just simply saying it kills people made me laugh but it did!

[@me0101001000]

A part of me wants to run some DFT calculations on these bad (very bad) bois. That could make them less, or even more cursed.

[@warlokyx]

Yeah a 1,2,3 oxadiazolidine with a an internal quaternary nitrogen is super not S-tier. Not cursed at all! 😑

[@bugabateinc971]

Interesting the epibatadine is a biological chlorinated hydrocarbon. I don’t recall seeing many natural organochloride

[@fantasticjames9451]

Zetekitoxin AB. Na channel blocker from Atelopus zeteki

[@kolbasz3584]

Love the new format, its really easy to understand and intuitive, great editing!

[@That_Chemist]

Thank you!

[@defeatSpace]

Pee stories, very short one, when I drink black tea I have blue pee.

[@Kualinar]

Pretty sure that the chemical properties of some of those will drastically change if they are folded in another way.

[@CAAStudios]

It would be really neat if you could explain in a more normie friendly way to make the content more digestible to a wider audience. Your cubane video was incredibly approachable For example: "This carbon group shouldn't exist. In similar compounds such as B and C, the carbon gets bound to a hydrogen like the well behaved children they are. However, due to the presence of Fluorine and literally nothing else, this is the type of bond we get. Absolutely cursed, and Absolutely does not appear in nature. This serves no purpose." (I know very little of chemistry so this example likely is wrong, but I hope the message come across)

[@That_Chemist]

Yeah I try to have a range of depth across the videos

[@GerinoMorn]

are you trying to tell me that someone could poison someone with a drug that gives them permanent(?) diabetes?

[@KanonXBlaque]

Wait are you a s3rl fan? Good look mate.

[@That_Chemist]

I love S3RL, and I was so stoked when he offered to let us use his music!

[@jsalsman]

Animations of space-filling balls and sticks are beautiful!