Will & Grace Most Famous Guest Stars: Part 2 | Will & Grace

The guests just keep on coming!
Fancy another? Look out for Part 3 coming soon.
And revisit Part 1 for appearances by Demi Moore, Jack Black, and Kevin Bacon!
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ABOUT WILL & GRACE
That's right, honey! A decade after their unforgettable eight-season run, comedy's most fabulous foursome is back. Debra Messing, Eric McCormack, Sean Hayes and Megan Mullally reprise their celebrated roles as Will, Grace, Jack and Karen. The 11th and final season of Will & Grace will feature 18 episodes. Behold once again, from the minds of Max Mutchnick and David Kohan, TV's wittiest ensemble ever. The legendary James Burrows, director of every original Will & Grace episode, has returned with a slew of razor-sharp jabs and dirty martinis. Will & Grace stands as NBC's most watched comedy in seven years. Originally debuting in 1998, Will & Grace has been nominated for 91 Emmy Awards, winning 18 of them, including Outstanding Comedy Series. The series has also earned seven SAG Awards and the show is one of the few in TV history where each member of the cast has won an Emmy.
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[@Ciclopea2]

Jack: "Say something Lesbionic!" Bonnie: "Home Depot." 😂

[@lizardwhispererfivehead3552]

😂😂😂 love this show More every time I see Repeats 😂❤❤

[@MarcosIsABaritone]

Damn! You beat me to it!

[@kimmy9737]

Macaulay Culkin was hilarious as lawyer

[@mahoganyjoy3502]

"Getting drunk & popping pills and whatnot." "Throwing hot cofee on me." I swear this show would have me in tears. 😂😂😂

[@Krawfordk78]

You never watched it ever?? 😢😂

[@DraGnFly007]

Will and Grace is one of the BEST shows ever!!

[@nathanaellee8356]

Jeff Goldblum,Gene Wilder,Ellen Degeneres, Patti LaPone,Janet Jackson, and of course, the late Beverly Leslie all made Will And Grace a real treat to watch.

[@gabrielle916]

Don't forget Molly Shannon, Gregory Hines, James Earl Jones, Britney Spears, Matt Damon, Kevin Bacon, Cher, Mira Sorvino, Dylan McDermott, Elton John, Michael Douglas, J Lo, Nick Offerman, Hall & Oates.

[@MarcosIsABaritone]

"Prove it! Say something lesbionic!" "Home Depot." lolololol

[@It_Is_The_Me]

@Ciclopea2 beat you to it

[@matzi1628]

the entire scene with Patti LuPone was absolutely amazing, it's a pity it wasn't shown until the end, brilliant writing 😀

[@JamesIpToronto]

When he actually tries to cut her hair during the credits. lol

[@imalwaysright]

Jack trying to contain himself is hilarious. Him grabbing her head sent me 😂😂😂😂

[@rosalyndnovigrod1076]

“Shut up Patti LuPone!!” 😂😂😂😂

[@antonioernesto7892]

"Shut up Patty Lupone!!... Shut your brassy magnificent trap! I don't wanna hear you sing; I don't wanna cut your hair! And I certainly don't wanna hear you singing while I'm cutting your hair!" Hahahahahahaha

[@appointedvillainy]

I hate when I randomly shout "shut up, Patty LuPone!" people don't get it. It's very disappointing. 😔Where are my people who get it? 😆😆😆

[@ssantelha]

That's the woman from one of the AHS seasons right? The singer at the gay bar?

[@NatzTalk]

"People either love me or they hate me!" 😂😂😂

[@franklynlugo5900]

​@@ssantelhaYes she is!! An Icon!! ❤

[@NatzTalk]

" I'm sorry! My head was practically in your lap! Do I get the part?!"😂😂😂

[@naomiclark3640]

Will And Grace Had Better And Funnier Guest's Than FRIENDS By A Long Mile❤😂😂😂

[@KangwaShula-gz9eq]

Really 🤣

[@TightyWhiteyTrash]

For sure and some of the celebs that made appearances that wanted to be on the show like Culkin, Gene Wilder, Rosie, Janet, George takei, Matt Dameon, Debbie Reynolds, Patrick Dempsey, Joan collins, Glenn close, Mike Douglas, Demi, Neil PH, jack black, Kevin bacon, Woody, Ellen etc are either retired, cost a lot of money, are very exclusive, AAA List celebrities and unfortunately, some that have been on the show are no longer with us 🙁 but they live in our hearts ♥️

[@TightyWhiteyTrash]

And how could I forget Beverly Leslie aka Leslie Jordan. So sad and he was such a gem and will always be an icon to me 🤍

[@pratyushdubey29]

And even more guests

[@jbrow5245]

FRIENDS cast had such great chemistry that were so funny all on their own and really didn't require many guests. They both held their own. And I loved both shows.

[@ClarissaReneXOXO]

“He was so big!” 🤣

[@NatzTalk]

😂😂😂

[@peterswift5703]

“Prove it, Say something lesbionic”😂

[@andrewbui8295]

"Home Depot"

[@peterswift5703]

<a href="#" class="seekto" data-time="145">2:25</a> How five can be the number of people in a ménage à trois? 😂

[@juicymiss87]

😂😂😂

[@kevinchambers1101]

For Jack it can be any number.

[@imalwaysright]

Grace’s reaction 😂😂😂😂😂 <a href="#" class="seekto" data-time="468">7:48</a> Not only is the writing top-tier, but the acting is too All of these were good!!! ❤❤❤

[@NatzTalk]

Her reactions like those are my fave because they're so spot on! 😂

[@toramenor]

There were so many great guest stars

[@Monogenixx]

Didn’t know Kevin McAllister (Macallay Culkin) became a lawyer after being home alone by accident 2 years in a row 😳

[@DeanMoxley87]

this was just before he turned in to Jigsaw.

[@ginao6810]

So he can sue his parents for negligence

[@glenmcclatchey7443]

Did he take care of all the Filthy animals

[@RAch711baby]

He needed to defend all the other kids who were left home alone 😂

[@vedaanderson7009]

Love This ❤️❣️💜

[@donnalichvarcik9358]

Rip to our beloved celebrities that are no longer with us they will never be forgotten

[@NatzTalk]

Rosie😍

[@Marchant2]

I love it when a video makes me laugh loudly.

[@NickButler83]

By the time it got to Patti Lupone I was done 😂😂😂

[@rhondacurtis9643]

Janet Jackson is gorgeous!!!

[@errolpletcher9186]

Mira Sorvino might not be the "most famous" celeb to guest on W&G, but she sure was the best imo. Her performance as One-Night-Stand Diane should have won her a guest comedy Emmy! The whole episode (Last Ex to Brooklyn) is one of the best. 👌

[@NatzTalk]

I totally agree! She had to put up with Karen! 😂😂😂😂

[@imalwaysright]

“Kd Lang you are a lesbian” 😂😂😂😂😂 The writing on this show always takes me out!!! 😂😂😂😂

[@NatzTalk]

It was the best..the shade, the subtle digs and the innuendos!💛

[@evilhag420]

The fact that WAG had some of the biggest pop stars in history is absolutely WILD!! Madonna, Cher, Janet Jackson, Elton John, Britney Spears, JLo just WILD!! 😭😭😵‍💫😵‍💫✨✨✨

[@maus0liam]

i mean, these are all gay icons, on an gay iconic show.

[@sidewickx]

J-Lo said she couldn't stop laughing the whole time she was on the set... that they had to do so many takes for her scene 😂

[@Dani-ICU-RN]

<a href="#" class="seekto" data-time="395">6:35</a> HOME DEPOT😅😂

[@ajvourakis]

“Honey no one’s ever offered to dismember a dwarf and make jewelry out of him…”

[@donnalichvarcik9358]

Rip gene Leslie Susan and other family members of will and grace that are no longer with us ❤️🙏

[@irltefferson]

Jack and Patty scene is my favorite scene.

[@di-jt6jp]

It is a testament of how great a show this was that so many iconic celebrities did cameos… Too numerous to mention!

[@reginafromrio]

I love how Will Arnett outshines Janet Jackson because let's face it...

[@hariseldon2450]

Wanda Sykes and Ellen DeGeneres, my favorite comedians.

[@hanginthere1101]

Leslie Jordan’s name deserves to be mentioned ❤ great clips

[@sights3255kamobrin]

It was only a half eaten muffin in a dirty freezer bag, "! Just wanna make sure that you got it"!!! 😅🤭

[@Garcelle1987]

Why did I not know Ms Janet Jackson was in this? What a lovely surprise!!

[@Usbluthooth]

Anita they say willie Wonka die 😂😂😂

[@chrissiebawn9357]

LOVE LOVE LOVE. Totally miss the show 😀🤣❤🙏🇨🇦😀🖖🤣

[@Gitchagoat420]

Thank you 😂

[@peopledaddy]

Shut up Patti LuPone 😂

[@hekate1971]

Mr Stein from the office in London ❤

[@blakemrolfsensanchez547]

Patti Lupone was great too bad it was short

[@apokryltaros]

You'd think a haircut would be longer.

[@It_Is_The_Me]

This is the first time I've seen young adult Macaulay Culkin

[@PaulM-ge7gk]

Graces reactions always kill me 😂😂😂😂 and she isn't even my favorite

[@Usbluthooth]

Con Mac hallen anita lol manicomio record 😂😂😂

[@peterdunlop2092]

Love Wanda Sykes. She's hilarious. And Ellen is funny as a nun.

[@GypsyRock]

<a href="#" class="seekto" data-time="201">3:21</a> ish: it sounded like will called him Mr decay.

[@harper7509]

FLUSH ALL

[@Usbluthooth]

Lol😂😂😂

[@alme7748]

What about Madonna, and Cher? 🧐

[@Usbluthooth]

Jaja😂😂😂

[@user-dj3bp5iu1r]

This is random but I miss that laugh tracks would feature the actors' laughs from earlier takes. You can hear Debra, Megan, Sean, and Eric all respectively cackle after certain scenes.

[@SailorGreenTea]

<a href="#" class="seekto" data-time="392">6:32</a>, 😆

[@AmbivertsBeLike]

Why not give double mention of the special guests in some of the episodes?

[@timsimms412]

@<a href="#" class="seekto" data-time="97">1:37</a> he totally got Deborah Harry WHAT settlement??

[@bretalleman9352]

need a video for queen madonna

[@peteradaniel]

For some of these I have no idea which one is the celebrity because they’re often joined by another guest celebrity.

[@romane1008]

"You are a lesbian!" transitions to Ellen Degeneres 😂

[@juicymiss87]

😂😂

[@robinhallett-yc3hw]

@romane1008- that was a stupid comment!! Not funny or clever!!

[@plasticbag4137]

I thought we are done with Ellen

[@tomwotton9]

<a href="#" class="seekto" data-time="56">0:56</a> He has a kid!

[@m0t0b33]

2 actually... if we're talking about Macaulay.. and so does little Fuller from Home alone.. aka Kieran.

[@timsimms412]

Ellen is so not an actress.

[@rocoent]

Janet is of course amazing but she had the worst script. That Jackson 5 joke made no sense, she was playing HERSELF

[@TightyWhiteyTrash]

I also loved *Nadine* . I know she’s in *Sex In The City* but *Will And Grace* is more relatable to me. That Nicole Kidman eyebrow joke was the best.

[@sidewickx]

She is annoying just like in sex and city

[@gregorbaby4269]

For me was the chicken with a swiss chard vest joke 😂... How the showrunners came up with the joke to sum up Will's character is beyond me

[@TightyWhiteyTrash]

@@gregorbaby4269haha yea. And then the one dark comment she made when she met up with Grace in the cafe and Grace was telling her that she will never be able to be with Vince cuz he likes men. Then Nadine just says something to the effect of like, “now I don’t have to [hurt] myself anymore.” But she said something else but I don’t wanna get in trouble on here lol

[@amyreynolds3619]

whiteytightytrash ,you're name fits you like well tailored suit. 😊

[@TightyWhiteyTrash]

@@amyreynolds3619why thank you! There’s zero shame in my game 😉😜

[@TightyWhiteyTrash]

*Gene Wilder* (RIP🤍), *Macaulay Culkin* and *Jeff Goldblum* were my favs. I used to love *Ellen’s* appearance as well, but she’s not a nice person.

[@bretalleman9352]

she used to be sad

[@TightyWhiteyTrash]

@@bretalleman9352I really thought highly of her for years until the stories came out and I saw the Dakota Johnson interview. I’ve worked in toxic work environment before and I’m sure many people have so it’s personal to me…

[@m0t0b33]

I still find her funny on the show... not every actor whose work you like, is a nice person in real life, so... unless you know them personally, try and take it with a grain of salt.

[@amyreynolds3619]

😮 Hope you all get paid for lying about Ellen Degeneres. You would make a lot of money.