You Are Only As Young As Your Immune System with Dr. Greg Fahy

[@Drkarafitzgerald]

📝 Sign up for our newsletter for the latest tips and insights! www.drkarafitzgerald.com/newsletter/ 🧬 Curious about your biological age? Take our Bio Age Quiz now! drkarafitzgerald.outgrow.us/drkarafitzgerald-6

[@vestasharp6861]

00:05 Promotion of the podcast and sponsors 02:37 Integrative Therapeutics and Exclusive Products Backed by Science 07:30 Dr. Greg Fahy and his team demonstrated aging reversal in humans by regenerating the thymus. 09:43 Successful reproduction of aging clock reversals in humans 14:21 DHEA may mitigate negative effects of growth hormone in older individuals. 16:37 Metformin and DHEA combination as an effective treatment for insulin elevating effect 20:37 Metformin at 500mg/day can improve insulin levels. 22:42 Challenges in launching ambitious trials for aging research 26:24 Immune system's impact on aging 28:19 Research validating physiological changes of Aging 32:40 Continuous enhancements to the TRIM trial protocol. 34:38 Dr. Greg Fahy discusses the evolution of the anti-aging protocol. 38:38 Female sex hormones impact growth hormone response and insulin levels 40:31 IGF-1 is a surrogate marker for growth hormone status 44:38 Developing an AI for making medical treatment decisions 46:32 Encouraging clinicians to contact for treatment exploration 50:21 Reprogramming the thymus can eliminate the need for immunosuppression. 52:28 Reprogramming the thymus can help in avoiding transplant rejection and reversing established autoimmunity. 56:16 Immunotherapy is a key part of re-educating the immune system. 58:11 About 30% of all deaths are caused by immune-related failures by the age of 50. 1:02:01 Kind reviews and gratitude towards New Frontiers

[@ortcloud99]

Do yourself a huge favor and skip the intro and start @6:16

[@dr.samierasadoonalhassani2669]

Thanks you save my time very grateful. I hate none sense.

[@nsawatchlistbait289]

Danke

[@mestrecacatal]

Thank you

[@evaocaferrer5850]

Thank you 💞

[@andrewwalker8985]

If you missed it this guy is 74…. Something he is doing is working!!!

[@anonymissed3611]

Hmm.

[@trucid2]

Really. He looks mid 50s.

[@andrewwalker8985]

@@trucid2 exactly. Doing something right

[@mary-janeowen8238]

He’s taken a cocktail of growth hormone, DHEA and growth hormone which delivers anti-aging benefits. Does he colour his hair? Who knows.

[@andrewwalker8985]

@@mary-janeowen8238 he reported hair colour change as a result of the treatment which is pretty cool

[@MillionairesBrainPower-mv9vp]

People give you 10 seconds, few give you 45 seconds to decide to leave. Your introduction is eternity. Mix you sponsors in the middle of your video, you are losing a ton of traffic

[@rmat007]

Tons of great content for those that have patience. Glad I stayed back and listened to the whole. Somebody got to pay the bills

[@taterflaps475]

Agree with this. As a first time listener, it's my last. Too many streams out there to waste it on bla bla bla.

[@bulkypug3811]

You should just get lost then. Goodbye sniveling db >🚪

[@ortcloud99]

I agree, that was incredibly annoying and boring.

[@galimir]

yep.Especially with this sad face on the thumbnail-not exactly looking like the Fontain of Youth 😂😂😂😂😂

[@Snowkatt26]

Work out hard, do short intense cardio and do heavy lifting full body exercise like deadlifts to maximize your growth hormones. I’m 61 and still kicking ass.

[@jamessouza7065]

you mean your 61 & still getting your ass kicked

[@EllieM_Travels]

I have no desire whatsoever to reverse aging completely, as I don’t wish to live forever in this world. I’d just like to not look like a witch hag in my elder years, and I’d prefer not to be in pain.

[@HardHardMaster]

You probably don't need to worry about living forever

[@ActivateMission2ThisTimeline]

Ketogenic diet is worth looking up.

[@jobyyboj]

Why do you think that if you're in pain free good health at 90, you'd want to expire any more than you do today.

[@aubreyvandyne5284]

@@jobyyboj I think people who are sensitive to injustice, who have seen a lot of negatives, who want no more of it won't have the same values anymore, even concerning good health. They likely become nonchalant about life. Then maybe others, who with the years, become callous, unpleasant, corrupted for having seen so much in such a long life. It might not be easy to appreciate or be a decent person with all the years. Some may think it would be best to leave this world and start fresh with just wonders, like an infant starting with a clean slate.

[@craigrichards5472]

I'm glad I stayed past all the sponsor talk. It was an excellent discussion. Thanks for your hard work and passion.

[@fourshore502]

but you can just skip that

[@matthew04101]

This is the most important study i've seen so far. I am very excited for this study. I want to get this treatment now.

[@L0U1SE]

Is it though? Why

[@matthew04101]

@@L0U1SE Everybody has thymus involution disease (TID). Everybody will die from TID directly or indirectly. It's the root cause of hundreds of deathly diseases ( cancers, heart diseases, lung diseases, brain diseases, chronic pain diseases Etc..). If you can survive those then TID will finish you off at the end. There are many articles written about TID and what it does to your body. Well it's just called Thymus Involution, but i would like to think of it as a disease hence Thymus Involution Disease.

[@matthew04101]

@@L0U1SE You can't have strong immune system with almost dead thymus. And immune system keeps your body healthy, balanced, and it cleans out trash in your body like zombie cells and your brain like beta-amyloid.

[@ActivateMission2ThisTimeline]

These drugs are dangerous. Be sure to research yourself.

[@drnicholas1]

did anyone hear how much mg of DHEA he was using?

[@jobyyboj]

Each element dosage is tailored to each participant's insulin response. He's working on an expert system to make those dosage adjustments automagically.

[@cm9748]

100-200mg 25 days on 5 off

[@jobyyboj]

This may work for you, but the TRIIM trial adjusts dosages based on blood marker readings.

[@cm9748]

@@jobyyboj Yeah, if youre seriously doing HRT you should probobbly spend 10 000's on tracking your IGF-1 and other markers make sure your hair doesn't fall out with the DHEA and you don't get toxic exposures to metformin and you don't develop diabetes and a super fat nose from the HGH or develop prostate cancer markers Yeah... Most people don't have the money. Obviously the Dr needs to make money somewhere and wants you to use HIS "AI" program and His Labs, because everyone needs to eat, but , What can My and other Broke ass people do to take advantage of the knowledge gleaned from the TRIIM trials ? I don't want to age just because I'm more broke then someone else, lol...

[@cm9748]

Read the Paper... Just google TRIIM-X Study.

[@lorisykes252]

This is not a new concept. Back in 1982, two scientists- Dr. Durk Pearson and Dr. Sandy Shaw talk about the thymus, HGH, and the immune system in their book Life Extension. They actually outline exactly what supplements they were taking. Good read if you can find it.

[@portalminer8813]

Their data for life extension was from short lived laboratory strains. There was no lifespan extension compared to the species. Junk Science.

[@heijin76]

The interview is awesome! Thanks!

[@CharlieChan-l6u]

So honest! So caring! Full of love for humanity

[@robertsmith6906]

Research shows an inverse relationship between longevity and Growth hormone so I would be interested in hearing how Growth hormone in his studies does the opposite. Does he believe that all the negative effects of growth hormone blunted by DHEA and metformin?

[@jobyyboj]

Good question, I'd also love to understand the mechanism explaining why most large animals have shorter lifespans. TRIIIMx is a temporary protocol, just enough to regenerate the Thymus and repopulate the naïve t-cell pool over a year to 18 months. It's repeatable as shown by a low-n TRIIM ->TRIIMx subcohort with a few years in between treatments, but how well that generalizes and how many times repeatable remains to be seen.

[@louiscstrieber5478]

How does berberine work as a replacement for metformin in this experiment?

[@wread1982]

Berberine causes anxiety due to its stimulation of neurotransmitters

[@bulkypug3811]

Actually, Metformin is a synthetic replacement of berberine to generate big $$$.

[@tommcgivern8020]

​@@wread1982Don't preach someone's experience as law.

[@lorisykes252]

Berberine could be a potential replacement for Metformin. However, it would be harder to determine the dosage. Inositol is another possible replacement. I’m a clinical scientist and have been experimenting with growth hormone as well as NMN and other interesting chemical compounds.

[@acs2777]

Do a protocol and link to the ingredients?

[@gmw3083]

In the interview, I believe it was mentioned that information would be in the description about how to enter the trial. But it appears that the current trial will be over soon. Is there another one after that?

[@rev.jonathanwint6038]

Going to say something that sounds completely off the rails. That was an old 1940 horror movie about an evil friend talk to who would steal thymuses from people to extend his life hundreds of years.

[@tubejam3156]

Do you remember the name of the movie?

[@robertdaniel8964]

Interested in receiving some educational infomation on your trials, also on how to reverse your age thanks

[@davidvandeusen3424]

First time listener, and now a subscribed follower

[@LuckyLuchiano-g8o]

He should try Global Crowd Sourcing, alot of people would be interested in this.

[@yvindgundersen6819]

Will red light therapy improve the thymus gland ?

[@in2caffeine]

Good work Greg

[@newhopeforhealing]

Helpful DIY tip: Pregnenolone in place of PM HRT, DHEA, Elk Antler (Igf-1) and Quercetin instead of Metformin. Thick dark hair, wrinkle free at 64.

[@b8dom]

Please could you explain that again but like I’m 10 years old ?

[@HappyCetacean]

@@b8dom Here's where AI really shines; I like Perplexity for questions like this: Pregnenolone and DHEA Pregnenolone is a precursor hormone that can be converted into other hormones like DHEA, progesterone, and cortisol2. Some people use it as a supplement, believing it may help with various aspects of aging. DHEA (Dehydroepiandrosterone) is often referred to as the "mother of all sex hormones" and is thought to have anti-aging properties2. HRT and Hormone Balance The suggestion to use pregnenolone "in place of PM HRT" likely refers to replacing evening hormone replacement therapy with pregnenolone supplementation. This approach aims to support the body's natural hormone production rather than using synthetic hormones2. Elk Antler and IGF-1 Elk antler is sometimes used as a natural source of insulin-like growth factor 1 (IGF-1). IGF-1 is associated with growth and regeneration, but its role in longevity is complex and not fully understood. Quercetin Instead of Metformin Quercetin is a flavonoid with antioxidant properties. The suggestion to use it instead of metformin implies an attempt to mimic some of metformin's potential anti-aging effects through natural means. Metformin, a diabetes drug, has shown promise in longevity research.

[@Walnüsse]

Metformin Berberin glycin milk thistle valine HRT l theroxin fasting Dhea !🏆

[@Walnüsse]

Do you have your perid still ?

[@newhopeforhealing]

@@Walnüsse I stopped having periods 17 years ago. My breasts and vagina still plump also. I use DHEA cream every other day (below navel- important), 1 elk antler and 30mg Pregnenolone daily. I am 5'7" 140lb Caucasian. Everyone is unique so experimentation is key. :)

[@edwhite2255]

Key takeaways? What is actionable here?

[@John-Galt-Misfit]

True, what am I supposed to do?

[@metabolights]

TL,DR: Diet: flavonoids like quercetin & Apigenin, carotenoids such as Astaxanthin, tannins from pomegranate and catechins from green tea conciliate a variety of functions improving immune system. Sleep: diet: exercise + Gut health (eat kefir, fermented foods, Greek yogurt, overnight oats, etc)

[@peteostro]

@@John-Galt-Misfitwait for the study to be completed

[@whitewolf6730]

I have heard this guy talk before, and I will tell you what I know. 1. Take Metformin, minimal, I’d imagine, plus some growth hormone, or generate it by correctly exercising, plus it seems red light therapy is involved and take DHEA. I have been taking DHEA for a couple of years, Glycine, Taurine, plus I do spot body red light therapy plus being in a red light booth for 10 minutes a week.

[@charleyarchuleta4932]

@@whitewolf6730what have you observed??

[@Arugula100]

Too many advertisements. That decreases the value of your podcast.

[@resekai]

An hour long but no timestamp :c

[@anonymissed3611]

I remember some of the chastised alt Covid docs discussing the importance if thymus.

[@matthew04101]

What if thymus involution is The mechanism that keep people from living forever ?

[@LuckyLuchiano-g8o]

🤔 The last days are supposed to be just as the days of Noah which means amazing technology, hybrid gmo animals and plants, and Life Extension.

[@LuckyLuchiano-g8o]

@@matthew04101 How am I doing that?

[@LuckyLuchiano-g8o]

@@matthew04101 Who said I was making decisions for anyone else?

[@matthew04101]

@@LuckyLuchiano-g8o sorry i was misunderstood. so i take it back and deleted my comments. my apology. my bad.

[@LuckyLuchiano-g8o]

@@matthew04101 No problem 👍

[@mrxatwork]

Doesn't growth hormone make your skull double in size? My protocols has turned my brown eyes green so there that.

[@Voidapparate]

Growth hormones changed your eye color?

[@mrxatwork]

@@Voidapparate No, growth hormone gives you a big skull like Joe Rogan. I eat carivore 90% no chemicals some supplements and outside in the sun will clean up your DNA.

[@h34lth01]

woah, could you expand more on that? how yours eyes colour changed

[@LuckyLuchiano-g8o]

You turning into the Hulk brother.

[@Walnüsse]

How?

[@whitewolf6730]

Thank you Dr. Interesting and motivational.

[@baelimajeed5299]

Thank you very much

[@americanfreedom1777]

Hmm, Try removing metformin and add C15 B3 keep everything the same ?

[@ginaprzyborowski4573]

Could I use bernerine instead?

[@walterski8377]

Have to pay her high hourly for specifics

[@BK-dy8jk]

I will do whatever it takes to live a super healthy extended long life because I am a caregiver and I have so many people that count on me that I must help with their lives who are struggling so this is what I need to do. There is a lot of suffering when you get older and it’s bad enough you have to die, but don’t need to suffer before you do. Number one complaint I hear is exhaustion, and then throbbing aches and pains in bones and joints, then it’s brain severe brain fog and weakness that causes a fall. I am here to serve, but I can’t do it if I am frail and sickly. I want to be like President Carter and help and give, but I want to live longer and work harder than he did. I only want good people to live for long life not the evil ones. Forgive me Lord for being greedy.

[@ShareefusMaximus]

This is my first video of yours... You can't do that at the start of your video. In addition to all of your other interests, you should recognize that you are a KZbinr and begin to study effective KZbin methods. That's what your sponsors would also like, eyes on you videos.

[@portalminer8813]

I'm curious why an extension of the maximum lifespan for the species is no longer the gold standard when claiming a slowing of ageing.

[@virgilkirschner5717]

Thymus regeneration. Look into Firma Vita bio regulators. Is our peptides. Some work some don't. No, not affiliated with the company in any way. Shop at your own risk. Thank you for your videos doc. Some thought-provoking information.

[@b12345bb]

Video starts at 3:50

[@ValiantFerguson]

Ive known Greg since I was 12.He was my big brothers good friend. He was over at our house a lot. My name is Heather Ferguson. Trying to get in touch. 😊😊😊

[@WILLIAMMALO-kv5gz]

How to regenerate the Thymus? I am wondering about this. Thanks for this informative video.

[@fourshore502]

look into thymaline peptide

[@TheNowRealm]

Best info

[@petererker2000]

This podcast starts at 3.55min

[@rizzobitz]

How might you help the hundreds of thousands of infants who's thymuses are taken during heart surgery every year, like my son's was, when he was a newborn? These infants organs are taken without parent's knowledge or consent. They study these infants as they grow and their health decays. Will anyone help these infants, children and adults, who's organs have been taken for 5 decades now, sold to pharmaceutical companies to make drugs like Rethymic, 27 million per dose and cell therapies using these babies organs.

[@eugeneflanagan1354]

I am 65 built 1000th of thousand of blocks in my time does that count

[@betzib8021]

Does this guy look like he has discovered the fountain of youth

[@izgl]

Depends...if he is for example 100 years old...he does. But i doubt that.

[@zer0thzero428]

74 - draw your own conclusions.

[@betzib8021]

@@izgl good one.

[@LuckyLuchiano-g8o]

A white guy at 74 with no wrinkles or grey hair? 😆 He's doing something right

[@betzib8021]

@Belikewaterb it's called clairol...or...good genes. My white grandma died at 95...no grey...auburn hair...almost zero wrinkles...she had not discovered the fountain of youth...unless you think alzheimers is a youthful elixir.

[@dennyoviedo4102]

She is an awesome speaker 😅lovely

[@plejaren1]

Thank GOD--- a KZbinr that TALKS and doesn't YELL when talking. SO rare.

[@MopedWheelieMachine-uw1zw]

Give us some great interest catching info right off. Give us a taste of what we actually came for!! Make it so we can’t leave. Once you get us hooked than pause to give your shoutouts to your sponsors.

[@MyBodyHarmony]

Fantastic information and something to stay up to date on! Thank you 😊

[@user-kc1ci8jg2d]

Very big issue hes not bringing up is iodine for thyroid most gh usage etc lowers thyroid. Any real bodybuilder will give u good info as many are experts in this stuff an what works. I knw people say crap but they dont get that big just taking juice its a science

[@katiekat4457]

I need this therapy really, really badly. Why can’t any of these trials be in Florida. And It certainly sounds like men will be outliving us for a long time. The reason for not focusing on women are already being stated. Lastly, I hope he extended his life already because he’s already 74 yrs old and he still has a lot of work to be done so I really hope he doesn’t die. Sounds like he is kick starting a revolution. Let’s just hope the FDA doesn’t get cranky or paid off to slow this down.

[@gdtoob]

Huh? I don't think you're familiar with the research. The first trial only had men, but the second trial, TRIIM-X, has women.

[@visnaidoogvn]

Interesting ✅

[@DutchUltra]

Lol those intro sponsorships were so CRINGE. IM OUT LOL 😂

[@cherryb6105]

Very interesting thank you.

[@Meeeeeeeeeeeeeeeeeow]

omg the intro leave it as outro next time

[@TrevorGopaul-jo1om]

This woman love to talk. Talk talk talk.

[@ortcloud99]

agreed, its way too much

[@jamessouza7065]

All woman talk alot ? All of them

[@robmcguckin7605]

@@jamessouza7065 21,000 words per day vs 7,000 for men. Look it up!

[@donnysingh6389]

No Actionable Advice 👎🏼 !

[@KasKade7]

Increase your HGH,DHEA,Vit.D and Zinc. Thymus regeneration. How? Ask ChatGPT. Seriously, the usual suspects. Fasting, exercise, sleep, sun, clean diet and low stress.

[@LTPottenger]

fasting also increases GH

[@borisnikas8248]

@@LTPottengerand saunabaths

[@peteostro]

The study is being done to get quality actionable advice

[@donnysingh6389]

@@LTPottenger thank you... I tried fasting but it backfired because I have mold exposure and mycotoxins were released from my fat cells when I started to use them for energy... causing a Herxheimer Response with negative symptoms... so I am trying to increase eating fiber such as lentils and beans to bind up the toxins and release them through the bile... any thoughts or recommendations ?

[@DavidRose-m8s]

Doctor Fahy talks very well, but his posture indicates he's ageing at least as fast as normal. Yes Metformin is linked to longer life ( Clock), but also to dementia. Not a good combination at least without the DHEA.

[@ortcloud99]

what are you talking about? He is the most youthful 74 year old I have ever seen.

[@robertcanastra2288]

@@ortcloud99 I think I understand where our user friend was coming from - his posture did not look great in this interview. Otherwise, however, he definitely looks and acts young for his age and I've seen him in other interviews where his posture looked fine.

[@greggbambu411]

The studies sugest that there is a small risk of dementia in those who stop taking metformin. Its the stopping that seems to cause the risk.

[@anonymissed3611]

He may have had whatever posture you're seeing since he was a kid. No idea what you're noticing,

[@jamiami3804]

@@ortcloud99haha my uncle is 75 and climes coconut trees like he's 18. I can't climb those trees anymore, too much American food i guess. He just run up in those trees like he was power walking on the ground.

[@dr.samierasadoonalhassani2669]

Playing with mouth head neck movement does not make good content too many wasted on liking one sound thinking people will love it . People are short of time want to learn .

[@gutante]

29:43 he crossed his arms immediately 😅 49:48 was her ✌🏿

[@PianoPatterns123]

Good Bye

[@Snowkatt26]

I don’t think this guy knows much of anything...

[@mangocat7255]

In Taiwan island we call her "chicken backside".

[@set3777]

2 conditions for longevity set by bible 1. Honor your father and mother Exo_20:12 Honour thy father and thy mother: that thy days may be long upon the land which the LORD thy God giveth thee. 2. Love God Psa 91:14 Because he hath set his love upon me, therefore will I deliver him: I will set him on high, because he hath known my name. Psa 91:15 He shall call upon me, and I will answer him: I will be with him in trouble; I will deliver him, and honour him. Psa 91:16 With long life will I satisfy him, and shew him my salvation.rom

[@srenbro916]

nonsense.

[@set3777]

@@srenbro916 But there are evidences! Go to Sardinia, Italy, and Okinawa, Japan where people have exceptional longevity and you will find that they honor their fathers and mothers. In USA, 2 different Christian people love God (so keep God’s commandments to the letter) 1. Amish people have longer life and much lower rates of cancer, cardiovascular disease, diabetes than other Americans. 2. Seventh-day Adventists, live an average of 10 years longer than the American life expectancy It is NOT even based on what THEY EAT..

[@baldsealion]

It's a myth. Try again.

[@set3777]

@@baldsealion Why do the Amish and the Seventh Day Aventists live longer than other Americans?

[@set3777]

@@baldsealion Based on what God promised, I believe Princess Catherine will live a longer life than Duchess Megan BECAUSE Princess Catherine honors her father and mother but Megan does not. It can be proven decades later.