I have narcolepsy and never understood how it's caused and why I can't just be awake like everyone else. I need more orexin lol

Useful

just a question, what determines which channel is neurotransmitter gonna open and if it opens K+ channel how is the action potential gonna travel on?

6:07 let me make a correction here Membrane potential is by convention calculated as the intracellular potential minus the extracellular potential. This fact is because the membrane potential indicates the potential of the cell interior in regard to the cell exterior which is typically negative so in neurons the membrane potential is typically equal to -70 mv. Finally Thanks for your clear explanation on this topic.

Thank you so much for this!

This should be more views :) Thumbs up for the excellent video!

This is the best instruction all over the Internet!

Thank you for making this.

AMAZING PERFECT VIDEO! Thank you so much, the vesicle cycle is very important for my understanding about action potentials. One thing I really love was how you visualized EVERYTHING, especially the proteins, so it's beautiful because you can keep track of everything, unlike just straight up showing non-moving images, thank you soooo much!

Thanks for the great explanation

please provide link to the poster above w/all details, Thanks, great work.

Nervous system!

Nervous system!!

Nervous system

Neuron's!!!

how you want it

Good

I really can't thank you enough 😭😭😭❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️

At 1:09:30 the labels for Lower and Higher lambda are interchanged ;)

Well then, anyone knows how ketamine increase blood pressure?

Wow, Thank You. Could you please share illustrations of the completed model?

Fantastic videos - looking forward to continue watching you

Would be great, if you could change the font style, and make the text easier to read and more prominent.

A great concept to cover would be cre dependent viruses in neuroscience!

3:00

Thank you Tal!

What an amazing video. WOW I love the depth you went into, much more useful for med students than the excessively simplistic videos elsewhere.

Thank you so much

Hi where did you disappear to ❤❤❤

Thank you so much, Jarur, Murshidabad,WB, India🇮🇳.

Thank w

👌

Hi could you help me on a problem similar to this one but with 2 “batteries” Na and K, 2 resistors and a capacitor ?

I was following so carefully until 5:53, when he said '''we're not gonna use it all", and then left with only 3 equations, with 2 are completely different with the last 5 minutes explanation he gave. Capacitance, for example. How come previously you said : cm = Ct / length (3:15) then suddenly at 5:53 it becomes cm = 2pi.a*Cm ??? Isn't Cm needed to be computed first using cm according to your own explanation at 3:25 ? Then how come suddenly cm = 2pi.a*Cm , if we need cm to compute Cm, but now we already know Cm and looking for cm (again) ? the same goes with the resistance equation, suddenly changed with zero explanation on how it's aligned with the previous equation on resistance. I felt like I slowly understood, only to be left in confusion again by the inconsistencies of equations

Great video, thanks Tal! I have one question: for the Gq pathway, does G beta-gamma involve in signaling like G alpha?

great explanation. I understood every part of it 100%. Thank you so much

What would the supplement agmatine due to glutamate I know it works NDMA receptor

How would one go about slowing down glutamate or getting rid of it for benzodiazepine withdrawal? If a doctor abruptly stop the medication? Patient has acathisia severe terror anxiety mood disturbance no medications are working looking for natural way to slow down glutamate or to gabba.

OMG YOU ARE SO GOOD LOL

fire bro. thanks

Thanks !

Great job!

Super good explanation

What really good lectures! May I ask you if there is any possibility to get your notes/scripts ?

Hi, thanks for all of your videos🙏🏻 I think you annotation at 12:51 is not quite right…? Shouldn’t it be “inhibition calcium channels” instead of “inhibition chloride channels”? Or maybe I’m wrong😓

Very good epxlanation

liked your video i like that you put the sources as well cause i dont want to listen without any sources liked plus subbed < 3

excellent animation and explaination, and it's very helpful for medical students like me. Thank you so much Tal!

Nice video, also I don’t understand Trial 1. Vm = -60 and Vc = -70, so we want a negative current to come-in (a.k.a positive current OUT of the cell, making Vm more negative). But you mentioned in Trial 1 that it’s an "inward current" (movement of positive ions INTO the cell) ? Isn't this contradictory to what you explained earlier? I see someone else asked exactly the same question, meaning this part is indeed unclear. I read your answer explanation in the comments, but it’s still confusing. How does that even make sense? Your explanation of inward/outward currents is based on positive ion movement, so it should naturally refer to the capacitive current (Ic), but suddenly you mention it’s due to the leak current (Il). Leak current isn't even in the the previous equation. Please help us to understand !

Great explanation! I finally understood shunting inhibition after watching this video😆😆😆😆