Short-Term Plasticity & Binomial Synapse Explained (Paired-Pulse Facilitation & Depression) | Clip

[@7egoss]

you are saving my whole college gradess, thank you so much and i hope you keep posting these science videos!

[@sciencewithtal]

Thank you for the support! Good luck with your studies!

[@davidklemetz2299]

Thank you!! Looking foreward to other videos on synaptic physiology such as dynamically primed synaptic vesicle states, tonic and phasic release, and loose and tight docked vesicles!:)

[@sciencewithtal]

Thank you, I'll keep those topics in mind!

[@otterb]

great explanation! pretty much on par with quality of my lectures, but appreciated the alternative perspective

[@sciencewithtal]

Thank you, glad it helped!

[@music-only7]

Short term plasticity facilitation and depression ---- Broadly, short term plasticity can be classified as synaptic depression and facilitation. Depression refers to the progressive reduction of the postsynaptic response during repetitive presynaptic activity, while facilitation is an increase synaptic efficacy. The link between neuroplasticity and depression ---- The changes in neural plasticity induced by stress and other negative stimuli play a significant role in the onset and development of depression. Antidepressant treatments have also been found to exert their antidepressant effects through regulatory effects on neural plasticity. What is the difference between short term and long-term synaptic depression? Short-term depression and long-term plasticity together tune ... Synaptic efficacy is subjected to activity-dependent changes on short- and long time scales. While short-term changes decay over minutes, long-term modifications last from hours up to a lifetime and are thought to constitute the basis of learning and memory. What neurons are involved or causes in depression? Stress, which plays a role in depression, may be a key factor here, since experts believe stress can suppress the production of new neurons (nerve cells) in the hippocampus. Researchers are exploring possible links between sluggish production of new neurons in the hippocampus and low moods.