Very helpful explanation. My husband started having unusual episodes a few years ago and fnd has been suggested as a possibility. His biggest symptoms are overwhelming fatigue, extreme sensitivity to light, brain fog, numbness and whole body nausea. The symptoms are significantly worse in the summer. He was found to have a Chiari malformation with restricted CSF flow and cerebellum compression. The neurosurgeon surgeon wants him to work with a psychologist before considering surgery and my husband feels very frustrated about this. He just wants the surgery and isn't really buying into this FND idea. He did have quite a violent childhood and he's had an unstable mood for our entire 35 years of marriage.

Everything I've come to believe my CFS/ME (since the 1980s) is, in one lecture. Extraordinary! Fasting/keto seems to lower inflammation and brain fog which is always a good thing. Now...to recalibrate the brain.... :)

Thank you, Dr. Matt!

Curious to know if you've seen intermittent fasting and a ketogenic diet help FND?

Watching from Fiji 🇫🇯

I would be interested in your metabolic approach, including diet and nutritional advice.

Dr Phillips, what's the best way to reach you?

Hello Dr. Mathew Phillips I wonder if you have studied the Dry fasting ebook of Dr. Sergey Filonov. It is my recommendation for you as a fan of your work. You 'have' to try this, to know if it is of real value for some of your patients. If done correctly 2 days of dry fasting has the samen benefit as 5 to 6 days of water fasting. Dr. S. Filonov is the best source to go to for dry fasting, his Russian books is summarized and translated in English. The book "20 Q&A About Dry Fasting" can be found on: kzbin.info/www/bejne/r5i5fod3pZ59eNU Besides almost two years of strict carnivore diet I implemented a year ago dry fasting to get more out of my healthy lifestyle, as a 68. From the different protocols I chose to go 2 days of no food and no water every month. It enhanced everything I wanted tot get from Carnivoor. Thanks, Michiel Slegten Netherlands

I can’t thank you enough for focusing on diet and exercise.

Are you seeing many PD’s getting good results while using fasting and Keto?

Finally! logical info. I had an operation and a week later pulled infected tooth....couldn't eat for days...made vegetable chicken broth ...after forced "fast" my parkinson symptoms diminished to almost nothing. I don't take l-dopa. unfortunately, I'm gunking up again and overdue for a prolonged week fast, see if I improve once again...that was a surprise and made me realize it is metabolic problem. TY for the presentation.

Thank you! I have been helping a 77 y/o woman with PD who just lost her husband who also had PD. I happen to be carnivore and follow Dr Berry and Dr Chaffee and found you. My dear lady was expressing her frustration at her predicament and said to me, "I'd do anything to fix this !" Of course, I had been waiting for this moment. I have been subtly dropping info I have learned and, along with her PD, she has had cancer and is type 1 diabetic from her 30's. She is a retired RN, and has a great handle on her diabetes with continuous monitor and pump system. I am a retired Respiratory Therapist and have been doing a lot of research on this. Your videos are helping me help her!

Hello Dr Phillips, Thank you so much for the incredible work you have chosen to do with your profession. May I ask whether throughout your clinical studies if changes in CRP levels have been recorded subject to a TRKD intervention. I ask as just recently I was reading a paper (PMC 4066441) on HD. CRP levels in pre-manifest HD were roughly twice those of familial controls and returned to approximately familial control level in manifest HD suggesting, it would seem, the possibility of onset being delayed through the management of CRP levels in the pre-manifest conditions - there maybe supplements which contribute but what of TRKD? Many thanks for your time. Steve (There is a paper PMC 9852883 looking at the effect of Ramadan fasting on CRP levels in HIV patients.)

I enjoy your videos, Matthew. I listened to this one and learned some new information. Thanks for the work that you do. If you are ever looking for new topics--ALS would be useful. I have a friend that is decining with it. I wish i had found your videos on mitohormesis sooner. He could have benefited from it but he is to the point of a feeding tube and has significant weakness. I am not sure if he would be up to the fasting and stress at this point.

On your research, I understand the environmental impact on Parkinson’s. How much do you feel that dietary issues, sugar and carbs that turn to sugar become a toxin to the body and brain?

Great stuff. The blind men could not see light either: kzbin.info/www/bejne/g320on6Afq55jK8si=aFpJ7buuQLHFkfxh

Red and near-infrared light are reported to benefit mitochondrial function. There are some videos on KZbin where light is used as a therapy for Parkinson's. Also, many bodily issues seem to stem from chronic inflammation. Grounding (earthing) is said to lower inflammation. You did mention forest bathing, which is related to both infrared light and grounding. Just more stuff people can try. It does seem like maintaining well functioning mitochondria benefits health in basically every way.

The myopathic form of CPT2 deficiency causes milder symptoms. It does not cause heart or liver problems. Symptoms may begin any time up to age 60. Symptoms can appear with skipping meals, a lot of exercise, or illness. Symptoms may include: Symptoms of low blood sugar (hypoglycemia) Temporary muscle pain Muscle breakdown Muscle weakness Muscle weakness (in the severe infantile hepatocardiomuscular form) How is carnitine palmitoyltransferase deficiency diagnosed? The condition may be diagnosed by a neurologist or geneticist. An infant may be diagnosed through standard newborn screening tests. The process to diagnose CPT deficiency starts with a medical history and a physical exam. Your healthcare provider will ask about your symptoms and past medical conditions. They may also ask about your family’s medical history. The physical exam may include a neurological exam. Tests may also be done, including: Blood tests. These are done to check the levels of acylcarnitine in the blood. And they check for enzymes in the blood that can show liver disease. Urine test. This test looks for a protein called ketones. It also looks for myoglobin in the urine to check for muscle breakdown. Exercise tests. These help identify the type of metabolic problem. Genetic test. This kind of test can confirm CPT deficiency. Heart tests. Tests such as echo cardiography can show if the heart is affected. How is carnitine palmitoyltransferase deficiency treated? A change in diet is the main treatment for CPT deficiency. This diet must avoid relying on fats for energy. It should provide a high amount of carbohydrates. It should contain a low amount of fats and protein. It’s also important to eat often. This can prevent low blood sugar. It can also prevent the body using fats for energy. And you should stay away from things that may trigger symptoms. These may include skipping meals, exposure to cold, stress, and a lot of exercise. The medicine bezafibrate may help to reduce muscle pain and weakness for people with the myopathic form of CPT2. What are possible complications of carnitine palmitoyltransferase deficiency? The adult myopathic form of CPT2 deficiency can sometimes cause kidney failure. This happens when muscle breaks down during exercise. This creates a chemical that can damage the kidneys. You might need extra IV fluids or dialysis to prevent or treat this. Heart weakness (cardiomyopathy) is a serious possible complication of some forms of CPT deficiency. A weakened heart may not be able to pump blood as well. This can lead to symptoms such as swelling and shortness of breath. Untreated heart weakness may lead to death early in life. Liver problems are another serious possible complication. Liver problems can lead to episodes of low blood sugar (hypoglycemia), often triggered by an infection. Untreated hypoglycemia can cause brain damage, leading to coma and death. What can I do to prevent carnitine palmitoyltransferase deficiency? If the condition runs in your family, you may want to see a genetic specialist before you have a baby. Genetic testing can be done to find out your risk of passing the disease to your child. If you do have the abnormal gene for the condition, you have choices. If you use in vitro fertilization, the embryos can be tested for the disease. Amniocentesis can also be used to test for the condition in early pregnancy. When should I call my healthcare provider? Call your healthcare provider right away if you think you are having an episode of symptoms. This includes weakness or muscle pain following exercise. Key points about carnitine palmitoyltransferase deficiency CPT deficiency is a condition that causes muscle weakness and other symptoms. It happens because of a problem with one of two enzymes, CPT1 or CPT2. The condition is caused by an abnormal gene. Symptoms can include muscle pain and weakness. If the condition runs in your family, you may want to see a genetic specialist before you have a baby. A low-fat diet is the main treatment for CPT deficiency. You may need to avoid activities that can trigger symptoms, like skipping meals or exercising a lot

It just occurred to me: Bickerstaff encephalitis and Wernickes encephalopathy can have exactly the same symptoms: encephalopathy, ataxia and opthalmoplegia.

Thanks!

How can Filipinos consult you? Do you provide online consultation?

Please have a research on young students and effects of ketones in memory, learning and cognitive function? How can keto help improve intelligence of students?

Any research on photo modulation with ketogenic diet?

Hi thanks for lecture. I think Romberg test is not normal in cerebellar ataxia. actually it is positive even with eyes open. the sensory ataxia only causes Romberg test to be positive when patient eyes are closed

I have been dealing with an undiagnosed debility for decades at one point I was getting tremors, they stopped after I did an exercise I thought up of deliberately jerking my hands and arms. But fatigue weakness and pain has been getting worse despite a careful diet and attempts to exercise which is difficult because of pain.

Thank you Dr Phillips. I have been following your work for some time now. I have a good friend who has Parkinson's and I was surprised to hear that his wife says that when he sleeps he does not have the tremors. What is the mechanism?

Thank you, Dr. Phillips, your lectures encourage me to keep trying to follow your protocols and reading Brad Maybury’s experience really gives me hope that I will be able to help myself cope with my Parkinsons. Do you know if following the Keto diet and intermittent fasting can address the constant lightheadedness that is one of the symptoms that I experience with PD?

As an IBM person, I am following your ketogenic diet therapy strictly. But I am perplexed as to your mention of oscillation - switching between stressor and recovery. Does this mean it would be better to follow e.g. two weeks of ketogenic with a few days with more carbs and fruit? Kath

Thank you once again Dr. Phillips for sharing info that helps me and others feel better. I'm following your protocols pretty closely with good results. I did the suggested keto diet, intermittent fasting, and exercise for five months last year, took two months off while moving, and have resumed everything for six months now. I track 12 key areas of symptoms and rate each on a 1-10 scale monthly then score each area to get a total. This gives me a view of how I'm doing over time. I've seen consistent gradual improvement in all areas. Interestingly, but maybe not surprisingly, during the two months off I maintained level scores for the first month and began to see a decline in scores the second month (an increase in symptoms). I mainly share this so that you have another person reporting positive results and so that others might be encouraged to try this. I also share your information at meetings for my local PD support group. Thank you!

PCD: progressive cerebellar degeneration LE limbic encephalitis SPS stiff person syndrome LEMS: Lambert Eaton myasthénie syndrome PERM progressive encephalopathy with rigidity and myoclonus

Thanks for another great explanation of this topic!

Another great presentation; Thanks! I'm surprised I didn't find your channel until just now.

Thanks for an excellent presentation Matthew, it's inspired me as a young-onset PwP just over two years in. I've adopted an 18:6 protocol. I've also been taking a lot of coconut oil (for its MCT content) along with ketone esthers. You mention in your video that both these strategies stimulate ketone levels, but don't bring about the broader metabolic benefits that fasting/ketone diet generate. I wondered how well researched this area is and how confident we can be that MCTs/ketone esthers do, or don't deliver the wider metabolic benefits. Coconut oil is pretty cheap, although ketone esthers have been costing me around £1,500 (~3,000 NZD) each year. Any additional research or guidance you could share would be very much appreciated. Thanks again for all your research and the work you are doing with sharing this important information. Mark

What were the proportions of fat by type in the diets? Polyunsaturated, Monosaturated and Saturated. And do you have view on what the effect is on the metabolism of linoleic acid at the mitochondria level?

Excellent presentation. It sounds like the Ketogenic diet actually had the most benefit in studies done so far. Have you done a video on that for Alzheimer's patients? I hope you will be able to do some long term studies. Dietary change usually has cumulative benefits from my experience.

Thanks

Thanks

What’s your protocol for Parkinson’s patients? My husband was diagnosed about 7 months ago. Do you recommend long fasts or only intermittent fasting along with a keto diet. I wish you were here in the US. If you need a PD patient for a trial, please reach out to me.

Thanks

I have been on many different drugs for epilepsy. Was on tegretol and lamotrogine before. Now on levetiracecam, frisium/clobozam, and vimpat/lacosamide. I'm 53 now. I occasionally have lorazapam. Been on many different drugs and still get seizures. I try my best to be keto.

I'm epileptic. Was diagnosed with it since I was about 12 years.

Parkinson disease is a very terrible illness, my Dad suffered from it for 19 years until we finally got a help and a medicine that truly works that helped treat, cure and reversed all his symptoms••My Dad is completely okay and healthy now

I was diagnosed officially with FND 2 days ago after it being suspected for 18 months by my specialist and having symptoms for 5 years. I hope with correct helps and supports I can have a reasonably normal life, however with my history of ongoing C-PTSD and trauma who knows…

Dr. Phillips, could you make a video about schizophrenia? 🛡🔰⚕

Helpful video , thank you

Lo felicito dr mathew por visualizar diferente y así exponerlo saludos y bendiciones

Amazing presentation Dr. Phillips, thanks very much for the incredible information. These findings are very promising, we just need to keep this keto and fasting life style for more years to be able to gather more information and find the truth. Personally, I was suffering from recurring bronchitis and irritable bowel syndrome, been fasting and keto for the last 3 years and now I could almost completely healed from the bronchitis (2 years and a half without it) and from the irritable bowel syndrome. I'm completely sure this is the beginning of a new era for the healthcare systems. Regards from Colombia!

My son was diagnosed with this two weeks ago, although he awaits a brain MRI to rule out MS.

Beyond fascinating. I’m a bit disappointed that such a potentially revolutionary approach to medicine isn’t garnering more views!

Excellent Presentation!!