01. What is sequence alignment?

[@AF-hv4yy]

You explained more in 11 minutes than my professor in 4 weeks, thank you

[@KevinBioinformatics]

Thanks for watching!

[@AqleemAbbas]

@@KevinBioinformatics Your lectures are awesome, If any post doc position in your lab let me know

[@mukailarashid5428]

Sir, you did a really good job in this video. It's been a year since i started learning bioinformatics but I was never sure of what was going on until I came across this video. I decided to comment before even finishing the video because I already got 90 percent of the concept. Thanks a lot.

[@KevinBioinformatics]

That's great. Hope you also like the other videos in this channel!

[@kidslove9248]

great explanation !seriously i have my exam in few hours and you made it just so clear..thanks a miillion!!!

[@KevinBioinformatics]

Thank you. Hope the video was useful for you.

[@babangapu8189]

Honestly, this is the best and simplest explanation

[@KevinBioinformatics]

Thanks for watching. Hope it was useful for you.

[@vikaanissimova6058]

Thank you so much! I'm reading a publication about MSA and your videos helped me understand sequence alignment! Very wonderful explanations - by far the best video about sequence alignment on KZbin.

[@KevinBioinformatics]

Thanks for watching!

[@tayyabsheikh4021]

Precise and well articulated. Perfect!

[@KevinBioinformatics]

Thank you for watching!

[@chitranshsinghchauhan6338]

Wow nice explanation 🙏

[@KevinBioinformatics]

Hope it was useful for you!

[@rajaramansoundararajan8246]

Well presented .... So Smooth !

[@mohamedkafafy6832]

great and simple

[@KevinBioinformatics]

Glad you liked it!

[@AshishSingh-sy3gn]

Thanks a lot for adding new videos, your videos are and very well explained.

[@KevinBioinformatics]

Thanks. Hope you enjoy the videos!

[@knowledgehunter6539]

Wow!! My name is Kevin too. So happy to subscribe to your channel🤗🤗 I really need in depth knowledge in Bioinformatics for my masters thesis.

[@KevinBioinformatics]

Hope the videos are useful for you! Comments are welcome.

[@sagek7949]

This was very helpful. Subscribed! I look forward to watching more videos. Thank you so much.

[@KevinBioinformatics]

Thanks for watching. Hope it was useful for you.

[@sbdranjani]

Well explained Sir.. Thanks for this video

[@KevinBioinformatics]

Thank you for watching!

[@Nokoli_]

thanks a lot. that was super helpful

[@ama-tu-an-ki]

How is this calculated in bayesian terms? What are the assumed priors? This must be an infuriating probabilistic problem, if we can't even assume the distribution of mutation frequency?

[@Angelica-dx2sr]

Thank you so much!

[@ehihihe]

Great explanation. Thank you

[@alexlee3511]

You explain it so well! But i wanna know if there is any reliable software recommend for sequence alignment since i found so many different software online

[@anuzis2]

This is so great. THANK YOU

[@oldPrince22]

哇 講的真的好好

[@KevinBioinformatics]

Thanks! Hope you enjoy the videos.

[@ramanobaid6249]

Amazing!

[@inshaishrat4371]

really helpful and easy explanation. thanks :)

[@KevinBioinformatics]

Thanks for watching. Hope it was useful for you.

[@Dr_Ali.Aljboury]

Why you not used word from the sentence I think it's better until we get the idea clearly I feel like dizzy from these alphabet. Please keep it like examples words am really need that way to understanding Tq so much

[@asayimusa]

this is great! Thank you so much

[@KevinBioinformatics]

Thanks for watching!

[@haleemabibi4123]

This was super helpful!

[@KevinBioinformatics]

Thanks for watching!

[@arielleariella3487]

Why is it important to generate alignment sequences using protein sequences and not DNA sequences?

[@KevinBioinformatics]

Usually there is a higher level of conservation at the protein level, and thus protein sequences can be better aligned than DNA sequences.

[@arielleariella3487]

@@KevinBioinformatics thanks 😊. I have exams in two days and I really needed to understand that concept.

[@waliullah7051]

didnt understand the 2nd rule can anyone explain plz or does it mean that at a single position in both the resultant sequences must not have a gap ATT-GC SOMETHING LIKE THIS? GCT-AC

[@KevinBioinformatics]

That's right!

[@irvingrondon3718]

Very interesting explanation, Do you have the implementation in Python?

[@KevinBioinformatics]

Glad that you like the explanation. I don't have an implementation in Python. I did ask students who took my course to implement the algorithm, and they have done it using different programming languages.

[@jacquelinelabovitz4613]

gd bless. thank you!

[@sirwesaeedi4159]

graet