Adapalene gel for anti-aging? 🤔 Dermatologist

[@humamumtaz2719]

I always advocate adapalene on your videos. I am 51 and have been using adapalene for decades now. People often comment that I look around 35. I don't have any wrinkles and only a few fine lines.

[@DrDrayzday]

👍🏼👍🏼

[@sayantaniist]

Wow..PL write briefly how you use.the steps pl

[@alexavasquez1992]

Yes, if that's you in the picture, you look absolutely beautiful

[@mamtaarora7174]

@@alexavasquez1992 yeah right Huma doesn't look like in 50's at all.

[@kylieshaye6562]

Can I ask how you use it, and how often? Do you use it over the entire face? I would really like to try this active ingredient!

[@ricorix3439]

So I use adapalene for now. The reasons why I use it are 1) the ease of access (while still knowing it's properly regulated and formulated), and mainly 2) I get the idea from the info available, and experience using it, that it's potentially not as strong as tretinoin. At this point in life (39 yo) I feel it's enough (together with all the other things I do) to keep wrinkles at bay and I don't want to overkill it, especially when considering stem cell depletion etc. I feel I will start with T when I'm about 45-50, or when I start seeing more stubborn lines. I just want to make a small point here in favour of adapalene. We have studies that, although small or not thorough enough, point more in the direction of it working than not (for wrinkles). Now taking that into account and knowing that retinoids work by binding to two different types of receptors in the skin: retinoic acid receptors (RARs) and retinoid X receptors (RXRs). The RARs are primarily involved in the regulation of sebum production and reducing inflammation (helps acne reduction), while the RXRs play a role in regulating collagen synthesis and skin cell differentiation (helps wrinkles). We know that adapalene is effective for acne, that is its label use, so it's enough to bind effectively to one type of receptor (RAR). I think it's is more likely than not that it works also in the other receptors. Again not saying it does since they are independent pathways, just saying that it is more likely to than not if you consider everything. In my case, and I may be biased (plus 1 case means nothing), I saw a considerable difference on my forehead lines several months after I started using it (about 4 years ago).

[@kathysharp7551]

Anecdotally, I've been using SPF 50 and adapalene for 2 or 3 years. My skin is super happy with this combo :) (age 45)

[@kathysharp7551]

And, I can us adapoline on my neck about every other day... Bonus just in case it helps with wrinkles ;)

[@mamtaarora7174]

@@kathysharp7551 what you are 45 , omg according to your profile pic you don't look in your 40's at all.

[@kathysharp7551]

@@mamtaarora7174 Confession, I was only 40 in that pic, but I'll take the complement all the same 😊

[@SharonBurc]

You look under 30 in your photo! Which adapalene and sunscreen do you recommend?

[@kathysharp7551]

@@SharonBurc I use differin gel; I think because it was cheapest when I started. And I use Skin Aqua spf 50+ UV Super Moister Gel (it's in a white bottle with a gold-ish top). it is a Japanese sunscreen that includes alcohol. It dries down without a residue. I do not find it drying on my skin, but my skin is pretty well balanced in terms of not oily and not dry. Also, it's super eye friendly. (For moisterizer, I use Cerave PM)

[@KFIGS-z3f]

I’ve progressed from cosmetic retinol ( one that dr Dray has recommended), to adapoline and experienced marked improvement in signs of aging. I then moved on to prescription tretenoin and saw modest improvement over adapoline. Just my experience, but I would say if you are on a budget, adapoline is the best bang for your buck.

[@mp5249]

That's my plan! 💖

[@cleogirl82]

I got the 0.1 percent. How do i find the 0.3%? Should I switch?

[@Hemmyii]

Same experience but I’ve only been on tret .025% so maybe at a stronger dose it would do better than adapalene. We will see! And I suspect adapalene .3% is prescription only. Never seen a brand sell one over .1%

[@myfuturepuglife]

@@cleogirl82 I recently bought the .1% Adapalene at Kroger and the Kroger facial sunscreen that Dr. Dray did a video on (very cute and funny video informing us about the new Supergoop dupe Kroger facial sunscreen SPF 40) and I'm glad she did because I love the shimmer facial sunscreen. I haven't been using the 0.1% Adapalene long enough to notice any difference ( just one application ) but I'm going to stick with it and use the entire tube before I decide to go up in strength. I may end up staying with the 0.1% We may have to go to a derm for the higher strength as I've only ever seen the lower strength sold otc. I'm ok with that because I've learned from Dr. Dray that a higher percentage doesn't always mean better results. Just be sure to use a good moisturizer and sunscreen on your face always.

[@youareinbarbados2578]

Thank you for sharing. While differin gives me terrible acne, tretinoin gives me clear skin in a few days. I was evaluated by the doctor having acne but being 34 was not covered for retin a. Derm gave me tazorac it didn't work. To buy retin at rx was 200 dollars too expensive. Moved to Europe I buy tretinoin for 20 dollars. TOTALLY UNFAIR OUTRAGEOUS people in US who need tretinoin have to pay such a high price, WHY. I'M DISGUSTED. I'M 47 now still using tretinoin works great, tried adapalene Differin, terrible acne. As soon as I stop tretinoin I get huge pimples. Something is wrong with the system in US, it needs to stop.

[@CAEO416]

I used tretinoin for 6 months. My skin looked slightly red whole time. I always used it over moisturiser and didn’t use any other actives. I also had a pimple most mornings after using it in the evening. I went back to adapalene. Redness is gone. No pimples and my skin is glowing again.

[@CareBeau]

Same

[@kathryngrace9038]

I’ve used both adapalene and tretinoin. When I was younger and acne was my biggest concern I enjoyed using adapalene. It wasn’t overly irritating and it definitely helped reduce my acne. As acne became less of a concern and wrinkles started to appear I switched to tretinoin. I definitely saw an improvement in the look and feel of my skin after switching to tretinoin. My uneducated opinion based solely on personal experience is to go for tretinoin if you have access to it and your primary concern is anti aging. Hope that helps someone out there:)

[@cafercan4267]

Did your wrinkles appear even though you continued to use Adapelen?

[@kathryngrace9038]

I am middle aged so I do have wrinkles. Nothing completely stops aging. That being said, I think I have less wrinkles than most people my age. I attribute the condition of my skin to tretinoin and I will definitely keep using it!

[@AnaMaria-ri9jg]

Did you break out? How did you start using it?

[@tiba5392]

Thank youuu❤❤❤❤

[@danieltenorio3559]

Can these be mixed

[@rebeccamcgraw6594]

When I use Differin, my face was not only acne free but as smooth as glass. People told me my skin was flawless.

[@camhunts]

I used adapalene for over a year. Switched to tretinoin and have been using for 9 months now. In my opinion, adapalene helped with controlling the severity and duration of acne breakouts. Tretinoin has helped improve the brightness, clarity, oiliness and smoothness of my skin. Tret helps control my acne breakouts as well. They both cause flaking in my experience but tretinoin has made a bigger difference by far imo and in a shorter amount of time. Also with tret I don’t have to use it every night, with adaplene I feel you have to be more consistent with application. Either one will be a game changer! 🎉

[@MrJulienn]

I hope at some point we’ll have studies about adapalene for anti aging because I’ve been using it for over two years and my skin has never been smoother

[@brendawei]

Honestly speaking, retinol wasn’t well known as an anti-aging ingredient among the general consumers until about 2years ago. But I have been using Differin for about 15 years already. I’m 44 now, and nobody thinks I am close to 35. I feel it’s just not enough scientific proof for Differin having anti-aging effects. But I know it does that for me. I am tired of retinols after trying for a year. So much for side affects. I am a minimalist, I won’t stop using Differin.

[@laalaa4303]

Is that you in your photo?! My god you're a walking advertisement for differin, my jaw is on the floor!

[@brendawei]

@@Jess-737 This could very much be a cultural difference situation. For Asians, not a lot of us speaks fluent English. Until about 2 years ago a KZbinr who lives in the US, started telling ppl about retinol, the skincare industry in Asia really just started advertising retinol in these couple years. I knew it, but I didn’t care to make videos to talk about it. The difference is really bazar. Such as ppl in the west are starting to get wild over Japanese skincare products and Korean products. And these products we have been using them for over 20 years. Isn’t that so interesting? I have created a KZbin channel planning to talk about these cultural differences exchanges. But I haven’t really started on how to elaborate this topic yet. It could be interesting.

[@dewisalim3320]

Hello, may I know what strength of Adapalene you have been using: 0.1% or 0.3% ?

[@davidflorez1196]

You use 0.1 or 0.3%?

[@brendawei]

@@davidflorez1196 0.1

[@Giselle_Gi]

I love tretinoin which I can definitely see its excellent anti-aging benefits. But the combination of benzoyl peroxide wash and adapalene is the most effective for my occasional hormonal/menopause acne around my chin area. 😊

[@CherieMonique5]

I’ve used both tret and adapalene individually for over a year and I can say tret gives me a much better “highlighted from within” poreless and even complexion result. I used adapalene for a while simply because I did not have access to tret and found it to be great to use while dealing with an active breakout BUT, with extended use I did not see the same super clear complexion as with tret. I have both now and use tret mainly. But will swap it out for adapalene+benzoyl peroxide when pimples arise.

[@OmegaMacheteStorm]

same

[@MsSonyfan]

What percentage of adapalene ?

[@s.a.6082]

Very helpful, thank you.

[@moni70963]

Adapeline works for me. It just takes longer than Tretinoin to see a difference, if you use it consistently.

[@youareinbarbados2578]

I would like to share my experience as well. Differin give me terrible acne , while tretinoin gives me clear skin in a few days. 47 yrs old

[@lucyi1202]

I used tretinoin for my acne for 3-4 years with no good results. All it caused was dryness and constant peeling. I switched to Differin and saw results in mere days with no purging. I’ve been using it for over a year now and I’m super happy with it. It cured my hormonal acne and post acne hyper pigmentation. I still avoid dairy and sugar but when I do indulge my breakouts are fewer and heal quicker. I also avoid fragrance in skincare and makeup and no chemical sunscreen.

[@727floridagirl]

It took 14 months (average 5 nights a week) but Adapalene gel took all of the sunspots off of my face, including a dark one on my chin that was the size of a nickel. Florida sun has not been kind to my face over the years. I can get Tretinoin for free with my insurance but my skin is pretty happy right now with the Adapalene every other night and 2 layers daily of SPF.

[@faithbelleg7465]

What kind of sunscreen do you use?

[@SunshineMichelle]

I use Cerave

[@Reignebow619]

I use adapalene on the back of my hands for almost a year and the skin there is more supple and smooth. So yeah, it works.

[@-l485]

i'm 43 and been using adapalene 0.1 for around 3 yrs. i would honestly say my skin is better now than when i was in my 20s or 30s. i dont have acne but throughout my adult life since puberty, sun damage from back when i was a teen to my early 20s due to sports causes me to have unbalanced skintone and im also easily prone to hyperpigmentation. i don't even use vitamin c, tried it and find vit c combo with retinoid (not used together obv) was just too much for my skin (so dry and itchy), so i uses only alpha arbutin, niacinamide and adapalene with sunscreen and a bha exfoliant once or twice a week. my uneven skintone and any pigmentation marks, and even the milia i had since god knows when, they have all faded tremendously in the past few years, i've even been commented my skin is glowing and asking what did i do. I'm considering the next step though. i think i'm ready to go for prescription strength retinoid

[@Himashree_333]

Do u use it under the eye

[@-l485]

@@Himashree_333 the differin? no, it will cause my eyes discomfort... i have been trying several vitamin a eyecream and currently am quite happy with the one from Beauty of Joseon, its affordable, cost effective and i even use it on my neck after i see another youtuber shows clinical test (albeit her own) sorta effective for the lines on her neck, i tried it, and do notice a slight difference on my own neck after 6 weeks use myself

[@haroldobrien9852]

I've used avene retinal for 10 years people think I'm in my 50s but I'm 74. I'd been considering switching to adapaline but was hesitant due to sensative skin. Think I'll stick with avene for now until more studies come out. Thanks again for all the good info you provide in your videos. You are my #1 trusted online skincare dr. 😅 Donna

[@SueRosalie]

what you want is tretinoin

[@hopeless_wanderer502]

I love the avene retrinal. My skin is very sensitive, too. My kiddo uses adapalene, and I've tried it a few times. It is a little more drying, so make sure to use that avene cicalfate. I also use the adapalene on the top of my hands (I apply it on my hands and then to my teenagers face) and have noticed the adapalene works way better at fading the dark spots on my hands vs the avene. Also, the retrinal I can use around my eyes and eyelids without issues.

[@ioanastoicovici5301]

I use adapalene daily and it was irritating just fist 2 weeks after that never got dry , I apply at night without any moisturizer… retinol was 1000 times more irritating

[@joannkodama2096]

At 76 I started alternating Differin gel and Paula's Choice 1% retinol, which I've been using for years. I think Differin just made my skin even better with no irritation issues.

[@AllyKit]

I used adapalene for one year before switching to .025% tretinoin. It evened out my skin tone and gave me a glow. But as a wiser person with dry skin who started late in the game, my deeper wrinkles respond better to Tret versus adapalene. It could be due to the cream vehicle of the generic tret versus the somewhat drying gel of the adapalene. Having experience with both, I do feel that adapalene would better suit a younger person with acne for prevention. In both cases, I applied every other day with moisturizer underneath, to compare apples to apples. Before those two, I started slowly with CeraVe retinol. My sensitive skin is so happy with the low dose tret that I don't feel the need to increase to .1%. This is all thanks to Dr. Dray of course!

[@sharonl2787]

What product did you use that your skin responded to the best?

[@AllyKit]

@@sharonl2787 Sorry I didn’t see this until now. That question is hard to answer. Do you mean which is the strongest? Honestly I’d have to say I saw the biggest difference using the CeraVe first, only because I wasn’t using any anti-aging products at all, prior to that. They each work extremely well in their own ways. It depends where you are at in your skin journey, your age, etc. If you can be more specific with what you mean by “respond” I can answer you better.

[@nabilatasfiharahman4585]

Hey, did you switch to adapelene after cerave retinol?

[@someonerandom256]

I've been using Adapalene for three years now. It's affordable and works well. I started using it for acne but it really helps my skin stay young looking. I'll be 40 in June.

[@sursitsigxkhzgiaits]

Happy very late bday!

[@catboxcleaner3532]

Dr. Dray, you are glowing! Wish I could be surrounded by your wisdom in real life. Thanks for being here.

[@RPBSpeaks]

I swtiched from retinol to adapalene/Differin almost 8 weeks ago and I have seen noticeable changes in my skin. It is brighter, clearer and smoother. I kept the rest of my routine the same, so I know the adapalene made the difference. My skin was already in good condition and I have a solid routine. But adapalene made a big improvement to my skin. I'm almost 48 years old and was considering moving up to retinal or even tretinoin. But I'm sticking with adapalene :)

[@alonaampuan6834]

How long you used d retinol before switching

[@RPBSpeaks]

@@alonaampuan6834 I’ve used retinol for years … probably at least 8-10 years. I never had a reaction from retinol and haven’t had any issues with sensitivity or redness from adapalene. I’m loving the results 🥳

[@RPBSpeaks]

@@alonaampuan6834 Hi! I’ve been using retinol for at least 15 years (Serious Skincare A Force XR serum )

[@brynnking5184]

I was so excited to see this video topic. Started using adapalene 0.3% at age 19 originally for cystic acne. It worked big time and I have been using it ever since. What I didn't realize for so many years is that it could potentially have an anti-aging side effect. I am almost 37 now and have zero wrinkles. I didn't even start wearing daily sunscreen until I was 33. In my experience the higher strength adapalene works. I know my experience isn't scientific research, but it is insane that this hasn't been studied in more depth yet.

[@ag5495]

Agreed

[@Jessica-re3ke]

so i am curious, you mentioned you didnt use sunscreen for so many years and still applied adapalene, did you ever get bad sunburns? just started differin for acne and every video/forum scares you about the dangers of sun burns if you are using retinols with no sunscreen 🙈 i would really like to tan from time to time this summer( just like sun kissed glow, not burn) but now im scared of how bad i might burn even if i wear sunscreen

[@brynnking5184]

​@@Jessica-re3ke I only applied it at night and washed my face every morning. I did use a benzoyl peroxide based prescription in the AM though which is bad for sun exposure too. My dermatologists over the years were not helpful in educating me (I've since learned most of my skin info from KZbin etc). I'm not sure if any of them told me I should wear sunscreen even though they were writing me these prescriptions. I was just happy I didn't get boils on my face anymore! And I did apply sunscreen on days when I would be in the sun a lot (pool, beach, etc.) because I have auburn hair and super pale skin so my skin burns very very easily.

[@brynnking5184]

​@@Jessica-re3ke actually I just remembered a terrible sunburn I got on my face at a football game in my 20s. I had NO idea it would be so sunny and I was stuck there for hours. It was a bad sunburn. But I had a few other bad sunburns before using a retinoid too, so who knows whether those prescriptions made my sunburn worse than they would've been otherwise.

[@Jessica-re3ke]

@@brynnking5184 Thats how i am using it too, just at night and wash face in morning. I agree that i also learned more from youtube about skin care than dermatologists 😆 i am only on week one, and nervously anticipating the big acne “purge” everyone talks about. I feel like differin will either work really well, or like some cases ive seen, cause a horrible breakout that never goes away and just makes my face worse than when i started 🙈 my acne is not horrendous, but just very consistent, never seems to go away and the scars also never fade…so maybe differin will help 🤷🏻‍♀️ thanks for your personal experience

[@crimbleland]

Differin was my first venture into the retinoid world, and gave me amazing results for acne and skin texture… I got that “glow from within” and even faded acne scars within 2 years. Now I have a prescription for 0.025% tretinoin and the transition went well, but I’ll always be grateful to Differin for being a more accessible option and it helped my skin so much!

[@ang3956]

That's where I'm at I want to transition from Differin to Tretinoin 0.025 did you purge starting tretinoin after Adapelene?

[@brookekasprzyk4850]

I switched from adapalene after 8 years of use to 0.025 tret and had no purging.

[@AllyKit]

@@ang3956 I switched from adapalene use for one year to tret .025 and no purging for me either. In fact I’m wondering if it’s milder? My dry skin loves the cream vs the gel!

[@ang3956]

@@AllyKit Thanks for replying

[@AJ_AJ.]

I started using adapalene because of cystic acne. Still haven’t solved that issue, but something I did not expect was my small little forehead wrinkles I’ve been developing (I’m 30) are quite reduced. It was a pleasant surprise.

[@pimiralii]

I used differin gel for about a year then I started using tretinoin and yes there is a HUGE difference. Tretinoin is way better and doesn’t really compare in my opinion

[@mleekahh]

FOR YOU. Look at the comments. Many people have preferred Adapalene over Tret. Some ppl have even left Tret to go to Adapalene

[@NadaAlawadhi]

Definitely needed this video! I just switched from tretinoin to Adapalene because of the long lasting irritation. I’ve been using tretinoin for 3 years and my skin didn’t get used to it. But suddenly the redness and peeling are gone. I love it!

[@1kelbrat1]

Same here. I've used every acid known to man, ceramides, and my skin has never fully gotten used to tretinoin no matter the strength. Consistent use of differin gel every night really helps with my texture, post-inflammatory when I get occasional breakouts and makes my skin happy and calm. That's good enough for me!

[@s.a.6082]

I just started tret, and I’m going to take it slow but be very consistent. I’m trying to not get my hopes too high because I’m in the category of people who it can end up not working for (fair, sensitive skin, I get flushed really easy when I’m embarrassed or upset) so I’m cautious and hesitant. I’m glad to know there are other options if it doesn’t end up working out for me!

[@balenciagahardcoreslave]

Update?

[@aleksandram7611]

The instability of tretinoin made me switch to adapalene. I refrigerated tretinoin and it still started to get weaker and lose effectiveness a month or two after opening. Adapalene is much more stable, doesn't have to be refrigerated and I noticed similar results with my fine lines, considering I'm in my early 30s, adapalene beats tretinoin and cosmetical retinols so far.

[@jeanettestalmack2183]

I love using adapalene for anti-aging. I switched from tret to Differin when it went over the counter in ‘17 (I believe). I didn’t notice any difference in effectiveness vs tret - and I actually liked the experience/feel of it better. Plus I love how easy it is to obtain; and it’s so affordable.

[@catacombss]

Can you please explain how you use it for anti-aging? I’m only used to using it as a spot treatment for acne lol 😅

[@taylorjenkins4517]

This was my experience as well. My skin peeling also completely disappeared when I discontinued tret and started Differin. My skin never stopped peeling with tret, even after the retinization period.

[@someonerandom256]

@@catacombss It's not meant to be used as a spot treatment like BP, although I suspect it would be effective. I wash my face at night, moisturize, and then apply it to my face being careful not to get it too close to my eyes. Some people say to moisturize after, or to moisturize before and after, but this has worked well for me.

[@PsiChotic]

​@Taylor Jenkins same. Almost 2 years on tret 0.05, use it 3-4 times a week and still plenty of irritation, redness and peeling. My skin only improved when I added azelaic acid, but the tret side effects still go on and I'm tired of it. I just ordered Adapalene and will start using it tomorrow night. Can I use it every night from the beginning or do I have to start slowly like with tret?

[@taylorjenkins4517]

@@PsiChotic I would try it once every third night for a week or two and then evaluate how your skin feels.

[@nathaliacarrera7848]

Ive been using use both Adapalene 0.1 and Retinal 0.1 (Avene) interchangeably for about 2 months and find that Adapalene causes less sensitivity and less dryness than Retinal. It works wonders for minor breakouts (almost gone overnight) and my skin texture is so much better - redness is better, pores are less congested and the lines around my forehead are less noticeable. I agree with others that on a limited budget, Adapalene works as well (if not better) than Retinal.

[@hopeless_wanderer502]

I've been using the same products! Avene never made my skin peel around my smile lines like adapalene, but it's sooooo expensive!

[@freshlimejuice]

I love Dr.Dray! She's so knowledgeable and cares if her subscribers get accurate information. Her vlogs are my favorite on the weekends though!💕

[@susanmcf1]

I used adapalene for 9 months for aging problems. It just dried my skin out without an aging benefit. Tretinoin has worked well for me.

[@fiftyshadesofpam9470]

Where can you purchase Tretinoin?

[@susanmcf1]

@@fiftyshadesofpam9470 I get it from Agency. Prior to that, I got it from Curology.

[@fiftyshadesofpam9470]

@@susanmcf1 Ok, thanks!! I need to try something different. Been using Lancome advanced Genifique along with there eye cream but not getting much results!! Ive been seeing a lot of women are talking about sun screens and how much they have in them that's good for wrinkles.

[@susanmcf1]

@@fiftyshadesofpam9470 Looking at the ingredients, it doesn’t seem Advanced Génifique would be helpful.

[@mamtaarora7174]

Unfortunately tretinion wasn't for my skin It gave me cystic acne I prefer differin more❤😊

[@DaliSalvador-Mel]

What an amazing work this doctor is doing !!!

[@MyLoVeLyMaN]

Adapalene 0.1 has transformed my skin and so glad I tried it! It took my long time to get use to it and being able to use it regularly - I have sensitive skin - however significantly improved my acne ( I still break out a lot - but spots are less, smaller, less cystic, and they don't stick around too long), smoothed my skin texture, brightened up the complexion giving me a very nice glow. Even if my skin isn't spot free and even in tone by any means, I can see and feel a massive difference in its quality. I still use it over moisturisers and has to be a tiny amount - otherwise I feel it messes up my skin barrier a bit. Epiduo worked great for a bit but too drying for long term use. I have tried tret and couldn't adjust to it. Now trying some retinal thinking it would be easier given my experience with adapalene, but still finding it a bit drying.

[@StonedSammieSue]

I've used .01% tret for years and recently hit some financial struggles that make it hard to spend 60+ on it right now. I tried adapaline by lrp in lieu of it, and I really like it! Honestly it makes my skin look a little better glow wise and pore wise than the tret, but I will say I have a few more pimples still where as I know they wouldn't be there if I was still on tret.

[@samk2377]

It's always so shocking to me when I hear about drugs being so expensive abroad. Where I live you can get a tube of tretinoin for the equivalent of 5-10 dollars usually.

[@mukesh3912]

Well in india it's less than 3 dollars.

[@werq180]

Hi. Idk if you still struggle with finding tret at an affordable pricepoint, but skinorac sells it for $10. it's an online pharmacy, no prescription needed

[@ignaciomenesesa6054]

I used adapalene 0.1% and 0.3% for two years, and I dare say, at least for me, it was much more effective and less irritating than tretinoin. After two years of using 0.05% tretinoin, I am seriously considering switching back to adapalene.

[@Gigi-ni1cf]

I started using Adapalene after watching your videos for anti-aging purposes. I’ve never had acne in my life and 3 months into using Adapalene my skin is breaking out like crazy I’m really close to just giving it up

[@mattbhagify]

What a great video as usual. I was literally pondering this question. You are the best mentor and teacher. Thank you Dr. Dray.

[@fernan7055]

The amount of things i learn from your channel its amazing

[@SunriseTango]

Discovered your channel 3 years ago, during the pandemic, and since then have been religiously hooked on adapalene, tretinoin, fragrance free sunscreen, simple fragrance free moisturizer and double cleansing. My skin looks incredible. People assume I spend a ton of money on treatments and crazy expensive skin care but I actually don't spend much (especially, comparing to before) since I no longer chase gimmicks. At 35, my skin looks better than it did at 21. Tight pores, zero breakouts, no dry patches/no crazy oil production (I have combination skin) and no fine lines. Absolutely life changing. Thanks Dr Dray!!

[@annette-in-vegas]

Do you use both adapalene and tretinoin? If so, how (both at the same time, or do you stagger when you use each one) and when (nighttime or morning)?

[@SunriseTango]

@@annette-in-vegas I initially started with adapalene to get my skin used to retinoids. I then moved to tretinoin 0.05 and now am at 0.1. I still use adapalene when taking breaks from tretinoin. If I am taking a break from tretinoin, I can use adapalene either in the evening or in the morning (followed by sunscreen). When I am using tretinoin, it's only at night. I layer it lightly on top of moisturizer and then follow up with Cerave Healing Balm (or Vaseline) - this helps keep any redness/sensitivity to a minimum.

[@SilverGirl-925]

I noticed a huge improvement in my skin when I started using a 50 spf sunscreen four years ago.

[@Duan2046]

what spf do you use ?

[@SilverGirl-925]

@@Duan2046 I use Skin AQUA spf 50+

[@evgeniaharel9323]

I have been using adapalene for 2.5 years. Gradually I have managed to adapt my under-eye area to this topical. The results are amazing: not only do I not have acne any more, my skin became so much brighter, radiant and uniform. I never use foundation or concealer. I get comments that I look around 25, and I am really really not…To your point, Dr. Dray, I do apply sunscreen diligently (two layers in the morning and another layer if I run outside). You mentioned on numerous occasions it will not hurt with long term use. So, with trerinoin so expensive, likely not covered by insurance and requiring prescription, that miracle topical, adapalene, seems to be a great alternative. Thank you for this clarification video on the subject!

[@RelaxWithReena]

I know this isn’t advised but I slug over adapalene (with aquaphor) haha and it def smoothes out my forehead and any creases. It’s never irritated my skin even tho I have super sensitive skin! I also think because the formula is so minimal in ingredients, my skin likes it more. Retinols I have tried just irritated my skin when applied over moisturizer, which gave my cheeks a saggy look. I don’t know why. I do want to try tretinoin in the future but for now, adapalene does the job really well for me.

[@crumbs22]

I’ve been thinking about switching to tret *because* of my forehead lines so I’m def gonna try that slugging thing before making the leap. Never thought to try it, thanks for sharing! ❤

[@Lvm4it]

Why is slugging not advised over adapalene?

[@kimlarsen8515]

I have been using Adapalene .1% on my forearms for actinic keratosis and been quite pleased with the results. Especially on the right arm which got less exposure when driving. Thank you for this! I’m taking that study to my dermatologist!

[@jesalinas00]

I or

[@angelamelum4304]

I started using adapalene a couple years after starting to use sunscreen. It made a huge difference in the transdermal water loss and the appearance in my skin overall.

[@Progr3ssNotPerfection]

I’m in awe. Thank you, Dr Dray!

[@veronicacarmody115]

I’m 63, I’ve used adapalene in the .01% due to adult acne since it became available. I have very few wrinkles and fine lines. People often think that I’m at least 10 years younger than I am. I’m also an avid sunscreen wearer, due to being a fair redhead. So, I’m not sure if it’s the Adapalene or the sunscreen or the effects of both.

[@SueRosalie]

most likely the sunscreen effect. If you use sunscreen daily it allows your skin to repair past sun damage

[@MDev617]

I started using adapalene for milia on my forehead. Besides working for that, my horizontal and 11 lines are definitely diminished without irritation.

[@Monicalala]

11 runs vertically.

[@ISAYHAYASE]

@@Monicalala she said horizontal AND 11 lines. aka horizontal AND vertical

[@MDev617]

@@Monicalala Yes, my horizontal and 11 lines are both diminished.

[@brookekasprzyk4850]

I used adapalene for at least 8 years for acne.. during that time I was discouraged by volume loss in my round face throughout my 20s. My skin looked great, no acne, and didn’t have wrinkles. I switched to 0.025% tret around 8 months ago and my pores are almost none existent and I think I am starting to see some collagen come back in my face. My goal is to build tolerance to the 0.1% tretinoin. I think adapalene is great for 30 and younger, sensitive skin or skin that can’t tolerate atleast 0.025% tret, or those who can’t afford the process of getting tretinoin. If you aren’t in those categories, go with tretinoin. Goodrx makes generic tretinoin affordable.

[@marimel89]

Do you think adapalene causes volume loss?

[@buntyjoy1800]

I have no negative side effects from Differin unlike the redness and peeling I had with Tretinoin

[@cenoviss]

Differing is awesome. In few weeks only,iv seen huge changes in my forehead lines.

[@jeffrendered3564]

used adapalene for a year, thought it worked well. cheap and over the counter. then i started tretinoin...there is no comparison for me. Tretinoin is the king!

[@SueRosalie]

after just a few months tretinoin gave me the smooth glowing skin I should have had years ago. I just wish I'd known about it sooner

[@meggieprice]

Being wiser these topics are always of interest to me! Happy Friday everyone! 💜💜💜

[@DrDrayzday]

Happy Friday 💙

[@lynndupree1205]

Boomer here, we didn't know how much the sun damages skin when I was young. I was very active outdoors- boating, golf, fishing, all while living at the coast and purposely seeking a suntan! Now in my later years I am spend many thousands of dollars to treat the signs of aging. Facelift, botox, fillers, and laser resurfacing. All are painful, expensive, and requiring downtime. Listen to this woman! It doesn't matter how many cosmetic products you put on your face, if you skip the sunscreen, you will lose the war!

[@jolina298]

Thank you! But many people think that sun screen is linked to cancer. And now they are making their own sun screen.🤦‍♀️

[@bigpoppa3020]

A sun burn is pretty indicative than ultra violet light damages skin.

[@ShoppingEmail-dr1fs]

so true, Aussie here, and I use vitamin C and retinol to clean sun damage and heal. but they're not expensive.

[@thereadaloudlady]

My boomer parents told me to get a dark suntan as soon as spring comes so I wouldn't have to wear sunscreen all summer 😆 I'm 35 and just now starting to get my act together when it comes to skincare

[@jenshahhater]

it has helped with wrinkles on my face and sun damage on my chest

[@normakeith4472]

I needed this video. I have been using Adapalene and my dermatologist approves!

[@WJYN7435]

For nuance, perhaps could we say that adapalene is a "pseudo exfoliant". Pseudo because its cellular mechanism is different than "true" exfoliant such as acids (AHA BHA etc.), but still sort of promote healthy new skin cells so to speak, thus giving a improved visual appearance of skin compared to nothing. So perhaps, we could say that at the very least, adapalene would work as a "pseudo exfoliant" giving more even skin tone and smother skin? What i try to say is that could we say that adding adapalene at least improves VISUALLY overall skin appearance (even though specific anti aging properties (wrinkles, fine line, collagen ) are not proven yet by studies?) (translation: Is using adapalene better than using nothing?).

[@paigehammond6752]

I quit using Differin gel to give retinols a try. It wrecked my skin. I’m not saying it’s bad! Just that for me personally I saw much better results with Differin. I even saw an improvement in skin tone (I normally get very red in the face that shows through concealer & foundation). I finally have gone back to my Differin and am beyond excited to get my skin back lol

[@dianamcmillan3285]

I use adaplene for my Milia that I get on my cheeks . It helps keep them at bay

[@bloop945]

Tretinoin really works for me, makes my skin glow and look younger. Adapalene/ Differin causes my skin to break out in dry flaky patches.

[@lindsayweathering]

Differin gel was around $9 at my local Walmart last tube I bought. Running low so just went to buy another - it’s now $32.

[@natasharoddy]

The 15g tube is about $15 and the 45g tube is $34. The price hasn’t changed since I started using it in 2019. Maybe you got it on sale last time?

[@JaimeMesChiens]

Lindsay, have you shopped Amazon for generic Differin? I use a low percentage Tretinoin. My Rx also has Tranexanic acid and Niacinamide. I also think that, because I began wearing SPF30 every-single day, that may be helping my skin very much. I enjoy Dr Dray’s channel very much.

[@Sovnarkom]

Buy the Curist ... $18 to $20 for 45g (3 month supply)

[@jesusmywholehaschanged]

​​@@SovnarkomCurrently, Amazon has Curist 90g (6 months) for $29.99.

[@sugarfree_2023]

It was quite hard to get used to differin and took about 6 months of hot flashes, burning and red skin 😂 but i never gave up and now i can tell you it is better than any other retinoid i tried (and i tried LOT of including Paula's choice, Medik8, allies of skin and etc etc). Skin is smooth, pores reduced significantly, and wrinkles simply erased. Love love love.

[@meghann84]

I've been using adapalene 0.1% for about a month now and omg my skin feels horrible. Everything I put on my face burns and stings 😢😭🥵🥵 what cleanser, serums, and moisturizers did you use? How long did your face burn and sting for? Oh, and I use it 3 times a week...Monday, Wednesday and Friday.

[@sarahayman449]

​@@meghann84 how's your skin doing now?

[@sable7114]

Oh hi, so I've learned something new. Adapalene for warts! Excellent!😊

[@robpar5282]

For years, I have been learning from Dr. Dray. Appreciate her way of explaining and her approach to evidence based information. I use tret (for over 20 yrs) and still have issues with discoloration, so it sounds like I should try differn for that.

[@rinskeverberg]

I used Differin every other night for six months but sadly, saw zero effect. Noteably, I do already have pretty okay skin with few fine lines for 41. I've found that I have a bigger challenge keeping my skin moisturized and the skin barrier intact, and that makes a bigger difference in the appearance of my fine lines. Just my experience:)

[@Sam-lp7vj]

I use epiduo (adapalene and BP) for acne. 1. Good anti acne 2. Good exfoliant 3. Good brightening PIH 4. No deep scar improvement 5. No anti aging results for me

[@monicahayes7921]

I had used tretinoin for a few years and didn't see much results ! So I switched to Aadapaline and my skin improved so much 😊 I can afford it too.

[@Alice-oe4kd]

Great video. It doesn't make choosing between products any easier but sure does provide a lot of information to work with.

[@donnamartinez5326]

I've used it for a couple years in my nightly routine and it has helped a lot! I have acne caused post inflammatory hyperpigmentation, and wretched sunspots! After about 3 mths? I asked my husband if he could see a change in the look of my skin and he said that my skin looked smoother. He doesn't usually pay attention to things like this, usually he would say, Oh, did you do something to your face, your hair, etc. This product works slowly but it has worked for me. My hyperpigmentation has faded DRAMATICALLY. But it took quite a bit of time. Wrinkles that really look like wrinkles, not so much. But, my expectations about them was low so I haven't been bent out of shape about that. I am 62 and I have a realistic attitude about my skin.

[@alvirarahman2690]

Okay so, I started using Retinol 0.2% with Squalane from the Ordinary. It was irritating slightly, and my skin slightly broke out at the beginning. But my skin started to tolerate it after 2 months. Now I am confident enough to move to 0.5% strength. Fingers crossed. Once I can tolerate the 1% Retinol for one whole year, I will move to RetinAl like Dr Dray suggested. Now I am just 26, my goal is to be promoted to RetinAl by the time I am 32/33. Hope that’s a good plan.

[@fearless6947]

well done for doing skin care at such a young age!!! Remember sunscreen, sunscreen and sunscreen!!!

[@alvirarahman2690]

@@fearless6947 I do use sunscreen! But like a dummy I started that at the age of 24/25 😭 spent YEARS in my college campus basking in the sun without sunscreen lol. Anyways I am really hoping retinol can reverse some of the sun damage.

[@meganwalker27]

Amazing forethought, wish I would have thought like you in my youth!

[@fearless6947]

@@alvirarahman2690 I started around 38. You are way ahead. Imagine how I feel, starting so late. I have at least 10 years more damage than you hahaha. We all live and learn ;)

[@shaunamoulton8764]

@@alvirarahman2690 i started sunscreen & skin care when I was 37

[@haveaniceday23]

Adapalene definitely improves my skin. Do I see noticeable wrinkle or age spots difference? No.

[@malonaudho207]

Hi Dr Dray! Thank you for your knowledge and kindness! Sending lots of love from South Africa ❤

[@stevedorecharley2849]

I have used Adapalene for anti aging, and it definitely worked. I switched back to Neutrogena rapid wrinkle repair, though, because the price per month was about the same, and I like the feel of it better. The Neutrogena also has a good moisturizer in it, so I don’t have to moisturize separately. I like having fewer steps in my routine.

[@lizzapaolia959]

You're a very intelligent lady. Happy Easter too you. God bless 🙏

[@sheila6797]

Tried it for two weeks skin much smother when I apply my blush looks so much better. Pimples and black heads drying up so much improvement.

[@kelseyomg5495]

Anecdotally- I’ve been using differin for about 2 years. I’m 32 currently. About a year ago I saw my first fine on my forehead, didn’t go away after a shower when my skin was hydrated. I noticed about 3 months ago that it’s gone.

[@RedElegance]

Informative and answers a lot of questions I've had for adapalene for wrinkles.

[@SnartNik]

Thank you. You are so articulate.

[@barbowens8626]

I’ve only been using the Gold Bond Retinol for about !0 days but the texture of the skin on my arms has noticeably improved! 🎉 Thanks for the heads up on this product! ☮️💚

[@kmon56]

Love the Gold Bond retinol and Gold Bond Pure Moisturizer. The retinol I use at might and the pure I use in the morning. I also have been using Differin Adapalene for many years after moisturizing at night. My skin at 66 is beautiful. No one ever guesses my age correctly. All this is thanks to Dr Dray. She's more informative than my dermatologist and no co-payment! LOL! She's the best!!!

[@AllyKit]

@@kmon56 I agree, I have learned SO much more from listening to Dr. Dray every day for three years versus seeing my derm who wants to refer me to her PA whenever I ask a skin care question and is in and out so fast she keeps missing my skin cancers.

[@rebeccamcgraw6594]

Me too, I have thin skin and have noticed no more scratches that bleed.

[@kayrabey1344]

Thank you I was thinking about trying that.

[@Isaiah41_10]

@@kmon56 so do you use the GB Retinol then the adapalene after nighttime cleansing? Do you use a moisturizer at night or just the GB moisturizer in the morning? Trying to make sure I do this correctly 😊

[@SueRosalie]

Thank you for this - people keep asking this question over and over on youtube and facebook groups

[@miguelpaul1164]

Rx .03 and using SPF since teens keeps me looking a decade younger than I am. Before that tazorac and retin a micro. When I had no access 0.1 adapalene did not and does not work the same as 0.3 and the stronger completely cleared me and has improved my skin with consistent use. 0.1 seemed to get me half way there but it was not enough. Tazorac the strongest is great too but not photostable and cant use with BP and harsh even when get used to it.

[@emersonpicks]

I've seen more benefits with adapalene gel after switching compared to tretinoin despite being on tretinoin for 2 years. I also noticed that my lines on my forehead started to look less noticeable.

[@mariaburger8774]

Thanks for the update! Have a beautiful weekend!

[@youlovejane1]

At the 9:35 mark, you mentioned they saw an improvement of wrinkles near the eyes. How is that possible if we are supposed to avoid the eye area with adapalene/tret?

[@Ash-oh6nh]

This video popped up as I was typing this into the search bar. THANK YOU

[@athenachloewoodrow6356]

I use tretinoin on my face and a little adapting on the rest of my body including my neck after I have moisturized. You can find good deals on generic adapalene and use just a tiny bit so I haven't found it super expensive. And I only do it once or twice a week.

[@CynthiaRodriguz]

For me, tretinoin wins. It has completely transformed my skin. 2 years in I still peel a little but it’s nothing I can’t handle 😌

[@tresjolieme81]

Vitamin C is a strong enough acid to build up my skin. It's brightening too

[@corismsyn]

Awesome presentation! Love the thorough discussion showing studies involved.

[@marieJennell]

I switch , I use tretinoin one night then adapline the next night... I use both around my eye lid skin upper n lower n zero fine lines even after I smile there's no fine crows feet left behind...

[@ghecho]

I’ve stuck to tretinoin because of its long and proven benefit.

[@DrDrayzday]

Tretinoin definitely has the most research

[@chinskichrupek]

Tretinoin is not available in the Europe …😢 I am using adaplene instead.

[@connordrake5713]

@@chinskichrupek don't be sad, adapalene is more ok than Tretinoin because the later had a great risk of irritation and peeling of the skin. It's a great test if your skin can handle Tretinoin or you can lower it on Retinol.

[@LuxLisbon32]

I live in Italy and can buy tretinoin over the counter. It’s called Tretinoina SAME and costs under €10. I believe this is the case in Spain and Portugal too? I actually don’t like this product, I found it too harsh. I like the French pomade A313, much more gentle and effective.

[@kam0406]

​@@chinskichrupeki wonder why it isn't available. It is long been proven to be very safe and effective.

[@ellenchristine5473]

I literally reached for my sunscreen after you talked about the limitations of the adapaline study regarding the sunscreen being used in the adapaline study 😅

[@ellenchristine5473]

I love your channel btw

[@pacha7977]

Dear Dr. Dray, your advice are far reaching. I was able to use adaptalene to refine pores on oily mature skin. I don't recommend it for use during the day, and one got to use sunscreen to protect the skin on the next following days. I use it once a week, max. Than you so much 💖

[@sameerkhan6234]

my suggestion would be to start with a low dose of tretinoin and then build up till 0.05 strenght, it is just like working out, your skin tolerates it. I have even used 0.1 % tretinoin, the one with the microgel

[@hbhb_31]

Yes I have been using adapalene gel 0.1% for acne, since last year and yes it showed me positive results. And Ofc SPF along with it. (No treatment done before, age- 23)

[@debdd7]

Always fantastic information. Thank you! I love Tretinoin. I use 0.01% currently. It has improved the appearance of my skin and faded sun spots.

[@horrorbyjuma4570]

I just wanna say thank u for anyone who recommended me to start accutane journey it was so hard tho but in two months I have no acne few scars and my skin is so soft like a glass lol

[@IIGeminiGemII]

Firstly: I think I'm I'm love with you. (For the record- I'm straight.) So, there's that.😆 Seriously tbough: With regard to the sunscreen study you mentioned- I assume the condition of participants' skin, at minimum, remained unchanged & experienced no FURTHER degradation bc they added sun-protection to their daily routines, but I'm wondering- Were there marked IMPROVEMENTS in skin condition that could be attributed to various/other ingredients within that sunscreen...ingredients that, as stand-alone products outside of "sunscreen", might not be proven effective against UV/UVB rays, but might possess anti-aging properties themselves, (ie: zinc)? Did the scientists detail that info? And do you have any tboughts on this being a possibility (or a proven definite)? Lastly (this question is re: totally different product): You may have talked about this in the past & I apologize if you've already covered it. I'm a newbie here: Do you have an opinion about using SULFUR-BASED products for their anti-aging, antimicrobial (acne), antiinflammatory, etc. effects? Do you personally have any sulfur-based product suggestions/go-tos? I've ONLY been able to find ONE reliable product (marketed for ppl w/Rosacea) and it's TINY & EXPENSIVE. 🙏🏼💜💜💜🙏🏼

[@nicksmith2975]

Me watching, realizing I've been using adapalene + benzoyl peroxide (prescribed for cystic acne, which was a holy grail by the way) religiously since 7th grade not knowing it was possibly anti-aging too😳

[@gregh2003]

How do u even get the discipline to stick to it for many years. Any irritation when first started?

[@21972012145525]

If you don’t have acne anymore, I would try just adapalene without the bpo. Not a derm

[@nicksmith2975]

@@gregh2003 i had terrible cystic acne and if i go off of the adapalene it comes back, so it’s easier for me to just stick to it constantly

[@leonab545]

I had no idea there was a solution to my acne and suffered well into my 20s

[@laceysmith6477]

Also, i think if tret is too irritating and u can only use 2-3 times a week compared to using adapalene 7 days a week, that could make a difference