Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

[@hubermanlab]

Thank you for watching. If you enjoyed this topic and episode, please click the "like" button and subscribe to our channel here on KZbin. Thank you for your interest in science!

[@Teabonesteak]

S'up player?

[@deleakindele5265]

Thank you 👍 God 🙏❤️ bless Andrew Huberman.You are a positive force to the human race 🎉 With love 💕 and respect from Lagos Nigeria

[@appino210]

Why ads for premium subs? It’s the only podcast I pay for and still am forced to listen to ads. It’s annoying man. Love the content but annoying

[@nounanouna7817]

Thank you for making science so accessible! I just wish if you could read the Quran and make an episode where you discuss the scientific evidence in the book. The very first verse that was revealed is: “ read!”. It’s all about science! Thank you!

[@lauralee8935]

Dr Huberman, your podcasts have taught me so much and also helps affirm the intuitions I have had about healing myself. Thank you! Please keep doing this AMAZING work! I appreciate you so much. Namaste 🙏🏻

[@Car-jy8pw]

I listen while washing dishes, cooking, cleaning… long story short, I have a large family and a full time job. These podcasts make information accessible and simplified to even someone like me. I truly appreciate it. I can make decisions for my family with a little less ignorance and feed my curiosity for things like this.

[@Snacktime_Jason]

Great response 🎉❤

[@vocaldancemusic]

good work ethic and good job supporting families, too many singles in california who are sad once they realize hookup culture is wasting your life. its good to know families exist and broken homes are the reason so many kids are messed up and cant pair bond and are gender confused

[@MsMoniqueLynn]

Maybe have the family help out so you have more time to yourself. Women make up 80% of all autoimmune diseases. Don’t get burned out. You can’t take care of others without taking care of yourself first.

[@studylondon5362]

I even listen to it when doin the deed…endorphins exploding all over her back🫡

[@CrossCultural-c7f]

Diego’s humility in acknowledging his research team is from the gut.

[@mlouw8218]

Dr. Bohórquez may be my favorite guest so far! I hope you have him back!

[@OnekamaProducts]

Lets get a video on the largest organ of the human body: Skin. Some topics to cover: Scar healing, sun burns, sunscreens, acne, winter dry skin, anti aging products, etc… You the man Huberman!

[@SerenityDreaming]

The entire integumentary system in general would be great. I'd love a discussion about healing touch like skin to skin for newborns, massage therapy, etc.

[@eyeofgumbo9610]

Yessir

[@drippy6706]

I've been given vitamin e cream for a bad cut on my face their almost no scar years later

[@treali]

@@drippy6706 I am glad for them but what about your scars?

[@treali]

No, I don't think that makes sense.

[@jodyglaser1]

At age 69, I'm still a curious person and especially like topics about health and understanding the body and how it works. Most times I come away thinking how in awe I am of the human body. What a marvelous creator we have who conceived of all of this. thank you for this tremendous work.

[@jopo7996]

This should be an excellent podcast. That's my gut feeling.

[@HarpaAI]

🎯 Key Takeaways for quick navigation: 00:00 *🧠 Gut sensing overview* - Gut sensing is not just about the microbiome. - Gut sensing involves receptors in the gut that respond to food components. - The gut communicates with the brain to influence emotions and behavior. 08:10 *🏥 Gut-brain axis explanation* - The gut-brain axis was traditionally thought to involve hormone signaling. - Recent research shows direct neuronal communication from the gut to the brain. - Enteroendocrine cells release hormones and make direct contacts with the nervous system. 17:01 *🧬 Discovery of neuropod cells* - Advances in neural circuitry tools led to the discovery of neuropod cells. - Neuropods are cells that make direct, precise connections to the nervous system. - Neuropods provide a faster, more specific form of communication compared to hormones. 23:39 *🧠 Neuropod Cells in the Body* - Neuropod cells are specialized neuroepithelial cells found throughout the body. 27:13 *🧲 Connectivity of Neuropod Cells to the Brain* - Tools providing resolution allowed the visualization of receptors inside cells. - Isolation of cells showed the formation of an interactive circuit in real-time. 30:38 *🧬 Neuropod Cells Sensing Nutrients* - Enteroendocrine cells in the gut express various receptors for different nutrients. - Sensing of macronutrients along different sections of the gut. 37:34 *🔬 Neuropod Cell Reactions to Nutrients* - Cells sense multiple layers of information from nutrients, including taste, absorption, and metabolism. - Detecting nutrients activates a chain response leading to the release of hormones/neuropeptides. 47:14 *🍽 Connection between gut surgery and weight loss* - Overview of gastric bypass and vertical sleeve gastrectomy surgeries - Reduction of gut surface area impacts hormonal changes and food preferences - Changes in physiology, hormones, and food choices post-surgery. 51:28 *🧠 Optogenetics in gut-brain research* - Explanation of optogenetics and its application to study gut-brain communication - Challenges of using optogenetics in the gut due to movement - Collaborative efforts to adapt technology for studying gut cell function. 57:46 *🍬 Sensory cells in the gut influencing food cravings* - Gut sensory cells play a role in food preference and craving - Neuropod cells affect perception of taste and influence behavior - Gut sensory cells calculate intensity and valence of food stimuli. 01:11:42 *🍔 Relationship Between Food and Gut Sense* - Ingesting highly processed foods can lead to excess calorie intake. - Evolutionary food choices shaped by convenience, taste, and variety. - Gut deconstructs food to shape future food choices. 01:16:02 *🥩 Influence of Protein and Fiber on Food Choices* - Removal of protein from a diet leads to food avoidance. - Animals consume more low-protein diets to compensate for protein deficiency. - Gut microbiome synthesizes essential amino acids in the presence of fiber. 01:19:40 *🥗 Plant-based Diets and Nutrient Combinations* - Agriculture focuses on planting complementary food pairs like fibers, sugars, and amino acids. - Traditional diets aim to balance nutrient deficiencies in plant-based diets naturally. - Nutritional arrangements on a plate reflect a mix of essential macronutrients. 01:34:59 *🧠 Fascination with the nervous system in physiology class* - Enchantment with the nervous system's control over life experiences. - Realization of the body's functioning similar to a machine. - Delving into synaptic terminal processes. 01:36:20 *🌿 Plants in the Amazon and their wisdom* - Plants possess extensive knowledge due to millions of years of experience. - Native people's profound sensory perception of the jungle and its elements. - Importance of plants not only for food but also for medicine and various functions. 01:41:51 *💊 Evolution of food choices and flavor preferences* - Trial and error in consuming different plants and nuts. - Neuropod cells playing a crucial role in discerning nutritious and safe food. - The sensory perception tied to food selection and survival. 01:48:42 *🌱 Plants as a source of medicine and psychedelics* - Many medicines are still derived directly from plants. - Plant-based psychedelics gaining interest in scientific and clinical research. - Incorporating plant wisdom into modern medicine for comprehensive effects. 01:58:35 *🍫 The Science of Chocolate and Guayusa Drink* - Ecuador is producing some of the best chocolate in the world, challenging Swiss and Belgian claims. - Chocolate quality can be enhanced by pairing it with unique drinks like guayusa. - Mixing extreme dark chocolate with guayusa tea creates a unique experience. 02:00:19 *🧠 Pathway from Gut to Brain and Sensory Integration* - Information from the gut is sent to the brain stem, particularly the nucleus tractus solitarius. - Neurons active in the brain affect cravings and food choices. - The gut's connection to brain areas involved in dopamine release contributes to pleasure and reward. 02:06:12 *📊 Electrical Patterns of the Gut and Circadian Rhythms* - The gut generates electrical patterns that change during fasting, feeding, and circadian rhythms. - Neurons like ENT neurons and interstitial cells of Cajal coordinate these electrical patterns. - Synchronization of electrical waves in the gut and brain may impact hunger and alertness. 02:11:14 *🤔 Gut Intuition and Food Synchronization* - Gut intuition involves storing past experiences in the body to influence feelings. - Shared meals can enhance bonding and synchronization of feelings between individuals. - Business decisions and even social connections may be influenced by shared food experiences. 02:22:02 *🧠 Vagus nerve activation and its effects* - Vagus nerve stimulation can induce arousal effects, not just calming effects. - Vagal nerve stimulators are sometimes used to treat depression, leading to alertness. - The vagus nerve acts as a superhighway with various inputs and outputs, influencing different physiological states. 02:24:23 *🎶 Gut-brain axis and sensory systems in the gut* - Specific frequencies and sounds can influence vagal activity and induce calming effects. - Humming has been linked to vasodilation, associated with a calming effect. - Sound plays a significant role in regulating arousal and calming responses. 02:27:08 *📚 Gut memory and the communication between gut and brain* - Memories associated with taste and smell are tightly linked to the gut. - Gut and brain communication influence emotions and overall well-being. - The sensory system in the digestive tract plays a role in memory recall and emotional responses. 02:30:05 *🤸‍♂ Listening to the body and gut sensing* - Paying attention to signals from the body, including the gut, is essential for making better decisions. - Learning to listen to the body's signals can lead to improved health and decision-making. - Self-care involves listening to the body and understanding its needs for overall well-being. Made with HARPA AI

[@Snacktime_Jason]

😂🎉

[@irishguyjg_2ndchancerecovery]

You should of listened to it, it was great 👍

[@adamtomecko6817]

My gut agrees, and informs me it might even turn out to be sublime.

[@MISSMOB]

One other main take away from this episode is this - I believe curiosity is essential to live a healthy life. I am someone who is extremely curious about the world around me, but I also have difficulty being around people and interacting. Give me animals and nature and I'll be happy as larry. When I'm invited to something, I always want to bail, last minute, but how I talk myself out is: "you don't know what you might have learned, or who you might have met if you don't go". Dr Bohórquez recalling his Thanksgiving meeting and the lady with the Gastric Band, is a fine example of why it's important to keep interacting, but also listening and taking in your surroundings. Dr Bohórquez absorbing (no pun intended) his conversation, mixed with his curiosity, led him to ask important questions and to apply it to his work.

[@NeuroReview]

Rating: 8.3/10 In Short: Neuropods are Gut Neurons (Yes, this is a thing) Notes: These gut neurons with hands that diego discovered are really cool--called neuropods. But the whole idea here is that we have neurons throghout our gut system that communicate with our brain and body, and I've heard this multiple times in the HLP and each time its fascinating and somewhat mind blowing. Then hearing some of Diego's story and how he got into science was great and made him memorable (south america, poor/humble beginnings). Plus 2x he says 'the words we have to describe this are bad', when talking about some nuanced concepts that are generalized in neuroscience. I get this same feeling listening to physicists or reading technical papers and I love when scientists think/say this. And especially since diego actually named something and wants to make it better means that he isnt just saying this, he's trying to do something about it. Cool also how he has a low key podcast but noone knows about it and huberman didn’t act like it was the best thing every (like he does with some other sci communicators) and just said a quick thing at the end.

[@hannespi2886]

I love your kindness, intelligence and humbleness Dr. Diego Bohórquez and Andrew and everyone involved making this possible, including you: the viewer

[@ebozzy13]

I want to pitch a great idea for this show: What if with each episode there was a simple quiz that would test people on all the knowledge contained in the episode? Created in a way that would activate people’s active recall. I bet it would help the material land much more solidly. Thanks for all y’all do!

[@lesliestucky2806]

This would be SO helpful… I get so turned on by all the info, but have a hard time explaining to someone else the next day

[@ianstratton5173]

Yes!

[@scotchbarrel4429]

I like it 👌😂 A fun game at the end, with Andrews guests acting like Lex and answering the questions in their own idiosyncratic way, id wager Lex in a black suit or a pirate outfit being a clown 😂 Or how he does his supplementary vids on his clips channel, like he did with McGill exercises, although the quizzes would be way more fun at the end of the vid.

[@evareynolds1277]

Oohh! I love this idea!!

[@Br0therHO0dClan]

I think that’s a great idea but with a tweak. Make it optional. You know how he does write up summaries on his website for each episode? Add a link to the end of it to test yourself on the material. Why? Because the ones who take the test are who this material is meant for and will take actionable steps.

[@elizabethmokrzycki7137]

Love this topic thank you ! I overhauled my eating habits! It makes such a difference no more symptoms of IBS. Grass fed meat wild caught salmon vegetables legumes kimchi and raw sauerkraut nuts when I do want something sweet it’s usually sweetened with coconut sugar no alcohol no soda. Olipop once in a while 64oz of water a day!! It took some serious stomach issues and depression to change but I’m very grateful. It started me on a wellness journey of meditation and yoga!! I crave healthy foods does anyone else? Lol😂

[@mineman662]

Huberman, I am 25, currentlyin a career in Software, I have to say, there are no words that can describe how much your content sparks my excitement to learn more about science. I want to pursue a neuroscience degree and I thank you for putting out amazing content. Kudos!

[@ageless1003]

Software to neuroscience...I like the transition. 😜

[@TravelPhotoWriter]

25 years ago Weight Watchers told us, "if you're hungry and craving high-point foods (i.e. Carby fatty), try eating some protein and waiting a little while." IT WORKED. Craving passed. And it's worked ever since. I am shocked at how I've become someone who does NOT crave sweets & starchies.

[@peshokelemeto2256]

Thats right! I don't even have cravings like before ... now i would eat 30g honey and it works + very nutritious foods, like eggs, meat, vegetables etc..

[@stefdiazdiaz7067]

​ Vegetables are toxic, hard to digest, full of antinutrients and with the wrong vitamers...

[@ken11238]

I cannot describe how much gratitude I have towards your quality contents, so please accept this small donation!

[@shannonevangelista]

Last year I was diagnosed with late stage colon cancer (which I sent right back to Hell💪🏻) and had genetic counseling which proved negative. I’ve also suffered from depression for all of my adult life. I’m obsessed w knowing if there is a correlation between the two. Thank you so much for this information.

[@vocaldancemusic]

get a hobby and stop focusing on what doctors tell you, get to a farmers market and grow more of your own food, get off the head meds and meet a strong man to support, most ladies these days dont have strong role models nor do they have hobbies to keep them busy, roominating does nothing for your health, ayurveda has all the answers heck even cannabis should be combined w/ calamus root yet people smoke it by itself and wonder why it has side effects, stop relying on farma and rely on natures cures

[@jeandicarlo-wagner]

Some newer micro biome info indicates that yes, depression comes from the gut. Documentary on Netflix explains. I am a 3c colon cancer survivor. Go plant based. Check your D levels. B 12 usually needed and after chemo our thyroids stop working. Follow the Society of Integrative Oncology.

[@danielnaberhaus5337]

Water fasting is what you need.

[@charlesb2895]

Water fast for 3 days and try a carnivore diet of only grass fed red meat. Cancer cells thrive on sugar. I know it sounds crazy but please search for anecdotal stories from other people in your situation and consider trying it.

[@endgamefond]

I am so sorry i am too having depression basically since i was in college. I hope you are getting better.

[@AmandaTorres-vr3mf]

I enjoyed this conversation so much! I felt as if I was eavesdropping on a conversation between two people who are on the same wavelength and have a shared passion. Dr. Diego Bohorquez exudes intelligence in a most humble way. Bravo amigos!

[@JenniferMyers]

Thanks for making your podcast easy to digest!

[@rebeccadand7720]

👏👏👏

[@duarteestelita8938]

this was ..hands down ..one of the best episodes, i’ve ever seen of yours. it’s unbelievable..the amount of knowledge that is beyond our current comprehension..just waiting to be revealed..studied..and shared . thank you so much ;) what a gift.. you have ..and what a privilege ..this service you and your team provide. kudos from Portugal

[@Algerhythm]

I have UC and anxiety and just as I’m getting over a horrible week-long rolling panic attack, this podcast couldn’t have come out at a more PERFECT time! Thank you 🙏

[@dr.samierasadoonalhassani2669]

I was 4 years old started primary school,Enter Baghdad Medical School at15 , Qualified as medical doctor at 21 years. First in medical school, 1 one year internship Baghdad then my dad smuggle me to Lebanon to fly to London, got a job within 3 Weeks , get post graduate degree in General surgery as the only girl with men . At 23 I was with surgeons from all over the world in Royal College of surgeons of Edinburgh, Scotland, specialised in Gynaecology and Obstetrics in addition to general surgery then did membership in gynaecology and obstetrics passed part one and two in one sitting in first trial . Rest is history. It was hard work but it is my decision to do it to help poor women in my country and UK and Qatar. Time and energy is limited so for me my life was only medicine, work and it is the only way to be the best . All traditional cultures value hard work no spoiling and waste of time in dally dally .

[@jojofreelancer1210]

As a person struggling with mental health and addiction at the moment I needed that last sentence

[@rebeccadand7720]

Amazing story. Loved it , congratulations on all the barriers you overcame ❤

[@dr.samierasadoonalhassani2669]

@@rebeccadand7720 thanks for your nice polite comment.

[@alwayshappy9943]

Stop this life now !! And do something different if you have enough time left . There’s more in this world than just being a medical professional . I had a similar path like you … I wish I had enjoyed the 20ies more

[@elainelennon4371]

Fantastic podcast very informative, what a humble amazing person Dr Diego Bohorquez is opened minded to all spiritual cultures, and a fountain of knowledge. Thank you to both of you. I have had bowel cancer and have always believed our gut is closely related to the brain.

[@lubaerlikh7170]

I will graduate from acupuncture and herbal medicine school next year and I am planning to go into the research because I understand the power of plant medicine ( like think about mushrooms being 4 billion years old!!! with all their DNA/ memory package). We need a more comprehensive approach to a plant medicine, it is time for it to be out of just folk medicine and become our "go to" medicine. Let's bring the medicine of the Earth back to people. Great podcast and guest, thank you!

[@Metta004]

Loved this episode! I need some clarification, though. When Dr. Bohorquez spoke about needing protein in the diet, he discussed plant and animal forms (if you remove protein, the gut evaluates no protein, and it stops eating that meal) . I didn't hear him say animal protein specifically was necessary. When you picked up on the discussion, you said animal protein. He then goes on to talk about how if vegetarians/vegans have a high fiber diet, the microbes can turn on the ability to synthesize essential amino acids, etc. My specific question--does the protein HAVE to be from animals? Or can you get the same results from protein regardless if it's animal vs. plant? The conversation starts at time stamp 1:15:30. He says protein, you say animal protein. Thank you for all you're doing for science. I use your podcasts as teaching points in my class all the time!

[@Evolutionofagoddess144]

Excellent question!

[@jenniferbalogh4090]

That is very interesting. If I understood it well, gut feeling is that your body gives you a signal first, before your brain could process what is really going on. So basically your body notices (you feel that unsettling feeling in your stomach) first the "red flags", and much later on, your brain also process it, and finally, after some time you came to an understanding about what was going on. First you feel subconsciously something is not right, and later that thought will become conscious, and from that point you will gonna become more aware. This is how I see it in a nutshell.

[@ronniechacon3909]

Greeting Dr. Bohorquez and esteemed Zamo colleague (I’m class of ‘17). I remember you giving a talk during a conference that took place on campus in Zamo where you showed the experiment about essentially controlling mice by stimulating their gut. That talk was so fascinating it left a great impression on me. It’s exciting to see you continue to be a trailblazer in this area of research! Saludos con la Z en el corazon!

[@KellyFisher-je7cm]

The whole time I was listening to this podcast I couldn’t help but think about my son who is almost 3. He is nonverbal and on the spectrum. He has a lot of food aversions which have gotten a little better through food therapy but we had bloodwork done on him and a Gut Zoomer and he has really bad gut inflammation and leaky gut. He was not born with these food aversions, they started at about 15 months old. I pray through research we can figure out how to help kids like my son with food aversions and sensory issues. I truly in my heart believe this is all connection from the gut to the brain.

[@shelly7017]

Have you tried the GAPS protocol?

[@in2097]

Every person I know on spectrum has seriuos gut issues from babyhood. I've remember from research somewhere that the two are connected.

[@KellyFisher-je7cm]

@@shelly7017 not yet. I feel like it would mentally be very difficult for me because of his food aversions I don’t think he will eat

[@roseymoloney9662]

I was interested also in how research might give us more information on this. I was sitting opposite a student who eats only beige food and has done for years. They had great skin, bright clear eyes, thick hair. Could we find out more also about hypermobility and gut brain links. It has been such an interesting pod cast and I failed Chemistry GCSE!

[@corilynchmueffelmann5889]

Wonderful company in the garden today - heartfelt thank you to both!

[@RevistaInstinto]

Thanks for this conversation! It was a pretty interesting topic since I see this process in my patients when they change their habits and diet. I experienced them myself when I changed my lifestyle 19 years ago and I was able to heal from IBS and many other diseases. There's lot of evidence of how the gut bacteria is able to control our cravings and drive us to the choice of healthy or unhealthy foods but the good news is that if you start to eat healthier foods your gut bacteria will also take you through that path. It's also very noticeable how the body guide you to the right choice of food, those that are more adapted to your system when you stop consuming processed food and stimulants (refined foods, processed foods, coffee, additives, etc). The knowledge of our need has been always carried by the instinct but the stimulants interfere in this language of the body and it's very difficult to perceive its signals while consuming them. It was nice to see someone coming from the Amazon doing research in this topic since there's lot to learn from the people who haven't been exposed to "modern life" and the lack of sensitivity that come along with it. Greetings from Chile and thanks for sharing this!

[@Chris-vj2hs]

Dr Huberman, I've learned alot from your r podcast and you're sharing something very valuable and educational to everyone to help them build a healthy lifestyle. I would really appreciate and be grateful if you could do an episode regarding emergency workers/first responders hectic lifestyle, how to cope with sleep food, exercise, managing stress, building strength and resilience and if it's still possible to maintain a healthy lifestyle despite the unpredictable working pattern. Looking forward to this episode. Thank you🙏🙏🙏

[@missrwlshorts3826]

I think only disciplined people can get along with andrew huberman's podcasts 😊 Really so helping without any kind of charges, all for free . Thank you sir 🙏

[@m00nbastic]

Dr. Bohorquez's science is so advanced that it has to be translated into regular scientific language. :D Amazing podcast! Thanks a lot!!

[@mariazamora4595]

Listen to your body, in my experience is to be able to understand the language of your body, understand the messages the body gives you, understand body, mind and soul. The nervous systems is the biggest antenna we have, and we have to understand, learn and listen to our body. Music and sounds for me has the power to heal. Sounds, vibrations, rhythms has the power to change a negative feeling or negative energy into positive. When I’m tired of thinking and need to empty my mind, classical and instrumental music helps me to relax and empty my mind. Our senses are a powerful source of our sensitivity and we have to learn to listen and understand our body. Our nature is to feel we are able to understand our body.

[@sulimangulzaree21]

Thank you so much my dear lovely brother for everything that you presented. I appreciated my brother ❤❤❤

[@jamielynne-magney2574]

As a somatic trained psychotherapist I appreciate the (too) brief discussion on intereoception. Learning to up or down regulate is a primary focus in working with adults with C-PTSD. Hope you can have Stephen Porges as a guest following Peter Levine and what is being discussed here.

[@everyonesalama4447]

If you didn't know already, he talks a lot more about interoception on another show, I can't remember which one but maybe meditation/mindfulness. Edit....I checked it is this one 'How Meditation Works & Science-Based Effective Meditations', the whole episode is pretty much based around it.

[@user-vi6ro8bd4l]

And VanderKolk (Body Keeps the Score).

[@BrainiousPodcast]

The episode I've been WAITING for! I have IBS which affects my life poorly. Thank you very much for sharing this content. You inspired me and my wife to start our own Podcast channel, you learn the best by sharing.😊😊

[@vocaldancemusic]

get to a farmers market and stop eating stabilizers and gums. its simple really.

[@danielnaberhaus5337]

Eat pickled veggies twice a day according to a different huberman podcast about the gut.

[@BrainiousPodcast]

@@danielnaberhaus5337 we do indeed eat pickles especially when I can convince him to do so! :)

[@1984FarmDreams]

This is one of the most fascinating topics to me. I live for this stuff. The gut, brain, microbiome . ❤️Fed my soul and my gut.

[@jessicalaughter7754]

This isn’t about this most recent podcast. But more so just an opportunity to say I love your knowledge and desire to extend yourself beyond your mind. Keep growing. Your knowledge can scale and touch so many people. There are others. Nicole LePera for example (I just learned of her yesterday) that understand the connection between biology, spirit, and mind. You could do some wonderful things with her. The brain body connection and helping humans bridge that gap is your calling. Keep growing. Thank you 🙏🏻

[@johnnyrayh5858]

From the information here and my own personal experience, I’m beginning to hypothesize that if you want to change your diet a serious fast might help with your desire to eat foods you previously weren’t interested in. My parents put me in a wilderness program at 17 and I lost a lot of weight, probably ended up somewhere around 30lbs under a normal body weight. My desire for fat became very strong. I remember picking fat of my moms pot roast as kid, but when I first had a roast after that experience I remember looking specifically for very fatty peices to eat. In short I think getting really, truly hungry might be a way to convince your body that whatever it can get is special.

[@deluciani]

Amazing conversation as usual but hearing about how gut can help us to take right decisions is something that was on my mind for so long ❤

[@HumbleBee123]

Hubez, can you do a video on how certain chemicals in carpet, sofas, mattresses, plastics, candles, cleaning products etc etc. (Synthetic hidden household poisons), effect the neurological, endocrine and other systems in the body. And what longterm conditions they can cause, eg. Thyroid issues, cancers, neurological issues etc. Thanks

[@endgamefond]

Carnivore MD i think he has been talking about thism

[@HumbleBee123]

Was that on hubermans channel. I dont trust anyone who classes their selves as carnivores because they aren't as knowledgeable about basic human diets etc and so would only trust people that Hubez trusts. And huberman goes so indepth too.

[@gb8518]

Dr Diego Bojórquez is fascinating to listenThree time I heard with so many details information storiesI learned & enjoyed so muchProbably will be back to the podcast for more infoThank you

[@jjuniper274]

You and Dr. Attia make it so hard for me to choose which episode is first?! :) This choice is such a fantastic one to have!

[@AngelRPuente]

Thank you Dr. Huberman, for the excellent information you provide on your podcasts. This one in particular holds my interest because of the relation it has with Hara breathing ( the spot approximately three inches below the belly button). Ancient theories have always held that from this point there was communication with the heart and brain. Now we know that there are neurons in the three sites. Having practiced Hara breathing for 60 years I have experienced phenomena that only now can be talked about with certainty. The main one being that by placing the sense of space in this area, what Dr. Les Fehmi has called an “imagless image”, it is communicated to the heart area and lungs, and to the mind. The effect is of deepened breathing, general relaxation, and clear empty awareness. In essence, the better fruits of meditation.

[@ЖеняБойко-з5у]

Signalling from the gut makes me careful with what I eat, cause it affects almost instantaneously both the mood and the ability to think. It also made me watch this episode. Though it seems not many people have such a feature. Anyway, thank you Dr. Huberman!

[@Naonicat]

My gut sense is leading me to this podcast 🙌

[@olgazavilohhina6854]

¡Hola Profe! I am so grateful to You and Your Guest for reminding us to listen to our bodies and all the signals they send us.Thank You for Your hard work and care for all of us.

[@sandykrieger5392]

Thank you! Dr. Diego is so humble.

[@amannaithani]

This will be very interesting. Due to the kind of world (which so much of stimulus everywhere and all the time) that we are creating we are loosing the ability to listen to ourselves, listen to our gut feelings. Looking forward to a deep dive in this episode. Thanks Dr Huberman for the sheer amount of work you put into creating such important content which is freely accessible to so many people and changing their lives. I am included in those people. Wish to meet you good health always and hope to meet you someday and gift you a pack of organic blue berries. 🙂🙂

[@karimahmad6674]

Suggestion: could you make a podcast about Schizophrenics? I am a huge fan and I love watching your podcast. Thanks❤

[@taralilarose1]

Read The Gut & Psychology Syndrome

[@oli7120]

stay away from drugs, even that really popular one you think is "safer than alcohol" LOL.

[@pricklycatsss]

@@oli7120How could you say something that dumb after watching this channel? lol there’s thousands of drugs in the world and you expect nobody to use any of them for any reason?

[@newday2637]

Such a great interview .. his story is so great . The gut brain information and function through the foods we eat , are so interesting . Thank you

[@angelinejolie.c]

As a Clinical Psychology Ph.D student interested in specializing in Nutrition and Behavioral Change this episode was so interesting! Such a great interview. Thank you! 🧠

[@DimitriCourant]

Are you considering an episode on the science of affirmations? What is BS? What are the best science supported evidence-based practices? It was touched on briefly with Dr. Suzuki but it deserves more

[@gracegracy2715]

My favorite podcast for health, Thank you for making these knowledge east to understand and available.

[@ToshaReece-CedarSlices]

For me, Both did a fine job breaking down the technical terms and concepts into a digestable form

[@nanbobbett4608]

I am extraordinarily grateful and blessed by your podcasts. Please continue sharing such excellent content.

[@AYDAN-eo5bqAY]

I always put your podcasts in the background while I bike, helps me get through long cycling sessions

[@lesleynorris3484]

Had to listen to this again and might do another repeat. Just so much of the more “technical” information to absorb.

[@jackm.1628]

Dr. Huberman, could you make a video on the most effective learning strategies?

[@mynosycats]

Thank you for your fantastic podcast! I just finished my finals and want to study psychology, I'm sure the knowledge I gather through your podcast will help! :) Not only that, but it's very informative and entertaining!

[@russell.r9580]

This episode was awesome , what a great guy. And you are the Best. I’m so proud of you and all you’re doing to cross and weave together all the intricate facets of our own human intelligence that so many rarely connect for us -while we innately feel their roles of importance…You provide me w faith that our scientists and professors are going to persevere from the outdated, restrictive guidelines and limitations that keep our own expansion and exploration contained and untapped on. You provide fascinating perspectives and help to shed light on the pockets that remain dormant, underfunded, and sometimes irresponsibly dismissed. Thanks Dr. Hubberman, appreciate you 💛

[@jeanne8264]

We need more talks about microbiom thou ! Thank you 🙏 ❤

[@littlesigh]

Another home run! So much valuable information! Yes come back!

[@melodym5993]

Thank you both. Amazing podcast. ❤

[@DueBaci]

What a great podcast! Thanks to you both ! I do believe our “gut” neurons make food decisions for us. Example: My gut does not like MSG. Naturally occurring glutamates ? Those are fine but, if a restaurant/kitchen sprinkles that MSG from a container on my food - even if I am not aware of it, within 20 - 90 minutes it (my intestinal tract) will expel the contents of my intestinal tract without my having any control over either the expulsion or the timing. Usually explosive. Can be very embarrassing 😢 My gastrointestinal tract also does not like A1 protein in dairy. I previously thought I was lactose intolerant. No so. I can drink A2 milk and eat A2 yogurt. I tried to eat Lactaid cottage cheese the other day. Nope. Discomfort. Love your podcast. This was the first one I listened to. I am now subscribed.

[@mariajosehidalgozambrano3868]

Thank you for so much love ❤

[@simonphuket7782]

Appreciate you bringing this knowledge to the world! I am grateful for Dr. Natasha Campbell McBride's and her GAPS nutritional protocol for giving me the excellent health I enjoy today. So grateful to the early pioneers such as herself and your guest who grasped the unparalleled significance of gut health to overall health and the powerful impact of the right nutrition needed to achieve it.

[@cherylnathanodette]

Although I fell asleep before the end, not due to the content. What I heard was good, thanks for keeping us informed, and so true always trust your gut.

[@mlouw8218]

This was wide ranging and interesting on so many levels! I loved the discussion of plants and traditional cultures… and the learning about the gut was particularly interesting to me since I’ve suffered from both digestive issues and bulimia for many years. My cells must be so confused and stressed out.

[@mariana_kyiv]

Our bodies are just amazing. This episode was soooo interesting, and it shed light onto some things I'd been wondering about. Now my friends are going to hear all about it! )))) Thank you so much!

[@paolaskeen6527]

What a wonderful discussion!. I enjoyed it like no other before, admirable guest. Thank you.

[@lisinbondi1240]

Listening to this makes the unscientific part of my brain go eeeewwwww!!!! There is way too much going on in my body right now ! Love it ! Thank you for informing my interest in science

[@gaurav007jadhav]

Thanks you ! Need more educators like you sir.

[@addeban]

I'd love to hear a podcast discussing the neurophysiological basis of clumsiness. It's sometimes hard to understand how people are capable of showing excellent fine motor skills and bumping into half of the interior or dropping everything at the same time. While it seems to occur when they're on 'autopilot' most of the time, it doesn't with other people!

[@SmartWatches-xu6ri]

Me too

[@dr.samierasadoonalhassani2669]

I mix my black tea with cacao and bean coffee at 5 am brewed in tea pot with one litter filtered water by reverse osmosis and black tea 2 tablespoons for all day drinking. The coffee and cocoa added at the top to get all polyphenols for my microbiome. Black Ceylon dark tea leaves are used and another pot for green tea leaves which is used also in the mix for EGCGin green tea.

[@jillchenok110]

Fascinating as always! The part about tastes changing after gastric bypass surgery-perhaps the neurons in the stomach are different than in the colon. My family member had their colon removed because of decades of inflammation from ulcerative colitis and early cancer. However, their tastes have not really changed at all even though they now have only a small intestine. Interesting!

[@arsalanniroomandi3109]

Thanks Andrew for your hard work and support of community. That would be great if you could make a video on Psoriasis.

[@mamasue7376]

So this is so fascinating to me this is why people really don’t feel well when the bow is backed up even more so than just general constipation there’s a malady that comes when the bowel doesn’t move regularly I’ve seen in my clinical practice over the years and this is just so fascinating to me. It’s a reality.

[@moorching]

Fantastic conversations!!

[@marcohannamusic]

Amazing podcast! Thank you guys ❤

[@Max-go4oc]

Hi Dr. Huberman, I'm Max, a 30-year-old engineer. Over the last decade, I've dedicated myself to health improvement, drawing inspiration from your work and others. I am looking forward to pursue this now with more dedication. Should I pursue medical school and get into functional medicine to deepen my impact, or use my entrepreneurial skills to assist others living a healthier and happier life? Your advice would be invaluable!

[@denisemenzel5530]

Thank you for these podcasts. It is helpful as I try to find ways to combat long covid. I know there are so many different ways long covid affects people, however, would it be possible to do a podcast on what is known of the neurological issues and where the research is focused. Thank you

[@lipingkang9630]

Wonderful talk, thank you to bring this interesting discussion!

[@Smeryrosu]

Great episode! Very interesting and informative! Thank you both!❤

[@mairavp]

What an amazing conversation!

[@fionabell1744]

Very interesting. Food is so much more than nutrition its information and how our beautifully designed bodies respond .. Facilitating how virus can change our behaviour too. Makes me wonder even more about what time will reveal around the whole covid debacle x

[@BijayaK.Shrestha]

A fascinating interview and a useful one

[@Vronihetherly]

Much gratitude for giving me a seat at the forefront of discovery❤

[@annamarsch6091]

loved this talk very much. especially the excursion to the plants. thank you.

[@jslull]

You can tell the educator in huberman coming out. The points he chooses to highlight and elucidate along the way really maximize the value of the message

[@MarRodriguezAguilar]

Absolutely awesome episode, besides mixing mate and guayusa, I also like to add coca leafs too to work for long hours or for working out. ❤ it is so good.

[@dr.samierasadoonalhassani2669]

Autonomic nervous system is still taught as two parts sympathetic nervous system and parasympathetic nervous system but third part of autonomic nervous system is nervous system of the gut( hence gut is first or second brain) and gut feeling. This third part is discovered by Cahall physiologist.

[@bertalippert]

1:22:05 Interesting to see the protein leverage hypothesis flushed out here and how fiber intake may influence the production of amino acids.

[@chazlon5061]

Right? There's one thing I got confused on though. Huberman said if I limit meat intake I'll have increased hunger. But what if I add more fiber at the same time? I think huberman might have gotten confused when he said that

[@cassiasouza6698]

Dr. Andrew, thank you for this conversation. Is it possible to bring up some professional to discuss Coeliac diseases and the connection with autoimmune disorders? Many thanks!

[@NursesLifestyleCenter]

Thank you so much for another wonderful episode, is it possible to have the citations about the gut microbiota's ability to synthesize essential amino-acids? That just blow my mind!!!

[@dr.samierasadoonalhassani2669]

Did very nice grass fed 5 percent minced meat with one cup cooked buckwheat and one onion and herbs. Now replaced meat with 2 cups orange lentils with buckwheat and one red onion in face put organic tomato paste. As sweet same cooked lentils with 3 tablespoon organic cacao ,1 tablespoon coffee beans powder, 2 organic bananas with its peel to make 3 tablespoons flax seeds and1 tablespoon Hibiscus to reduce my systolic blood pressure. In air fryer 180 Celsius for 15 minutes. Amazing browning cake with black tea.

[@PrincessThuya]

@hubermanlab thank you for this enlightening episode! It filled me with greater awe regarding the intelligence and amazing technology of our bodies! I am seeking some more tools 🧰 and guidance for my loved ones suffering from IBS, Crohn’s, etc. We now understand it’s a malfunction of the “gut-brain axis”, yet what can be done to correct? Thank you 🙏🏼🤓

[@susanjones5592]

A wonderful episode. Thanh you.

[@mattrichmond8399]

I was driving between Quito and another small town in Ecuador while listening to this, funny surprise to hear the origin story in El Chaco while the Andes are literally out my window. I live in Quito but am from North Carolina, we went opposite directions 😂

[@seon-gyoungadams2257]

Oh my , this is a fascinating discovery!!

[@SerenityDreaming]

So excited for this topic! Awesome!