Chromosome structure | Chromatin organization | 3D chromatin | levels of organization in chromosomes

[@juanpabloprieto4929]

This is amazing, I had trouble finding videos that explained chromosome territories and the topologically associated domains. Very good graphic!

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[@mgc000]

One of the best explanatory videos on a much confusing topic!!! Thankgod I found this😊

[@animatedbiologywitharpan]

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Sure!😇

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Heartfelt thanks for highly informative and student friendly videos.

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Your lectures really teach me a lot. Thank you

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This video helped me a lot

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[@fatmabetul5985]

my favorite channel :)

[@animatedbiologywitharpan]

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[@varshameena9742]

H3 and H4 forms tetramers , H2A and H2B forms dimers

[@animatedbiologywitharpan]

Ya i think in the video its mislabeled as tetramer while the image shows its dimer. Thanks for pointing out this detail. We should have been bit more careful and accurate.

[@varshameena9742]

😊 your welcome.... But I love the way u present biology in animated video... It helps in imaginating use more and help in learning

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@@varshameena9742 thanks please share them with friends and juniors

[@student9616]

What is dimer

[@nibrasulhaque2887]

very simple and informative, great job

[@animatedbiologywitharpan]

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[@urvashianand9399]

Very nice lecture sir, simplified the topic very well..

[@animatedbiologywitharpan]

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[@aj-uo3uh]

I suspect this inter chromosoom interacton is why certain translocations like t(8,14) are happening. The myc gene appears on chromosome 8 and the heavy chain on chomosome 14. Both are important and they maybe have a certain central position in the nucleus such that their rna can be easily made and transported out o fthe nucleus.

[@MichaelSmith-jt9qd]

Does the chromosome cycle between being fully condensed/packed/raveled and unraveled? It is amazing to imagine how the chromosome can “respool” itself without getting tangled. Thank you and nice video. 17:49

[@animatedbiologywitharpan]

Yes chromosome is really dynamic it can take up all kind of conformation based on cell cycle stage

[@suhagenetics]

This soo good!! Thanks a lot!

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[@wastman9762]

I just want know about continuity of chromatin. Is dna or chromatin a continuous throughout nucleus or they are separated into sections or fibres?

[@animatedbiologywitharpan]

Good question my friend. Chromatin is not continuous throughout the nucleus but organized into discrete regions. It exists in distinct chromosome territories, with further divisions into topologically associating domains (TADs). Chromatin dynamically shifts between euchromatin (transcriptionally active) and heterochromatin ( transcriptionally inactive) while being packaged into nucleosomes and compacted into higher-order structures.

[@jacktravers5049]

Yes they are seperated, you have different chromosomes (a combination of dna, rna and proteins (histones)), a pair of each autsomal chromosome 22x2, and two sex chromosomes, X +X(women), or X +Y (men). There is a continuous strand of dna envoloping one sister chromatid ( the picture you usually see of the classic 'X' chromosome are two "sister" chromatids(one from each parent)side by side, anchored at the center. The position of dna within the jucleus has an effect. The silenced X chromosome or "barr body" is a trancriptionally inactive X chromosome belonging to women. It resides on the periphery of the nucleus. If you have ever precipitated dna, which isnt hard to do, you can see it consists of strands.

[@anshikasingh8423]

Well explained 👍

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[@anshikasingh8423]

@@animatedbiologywitharpan yes ofcourse 👍

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Thanks a lot!! It is really helpful.

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❤❤❤ very helpful

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@@animatedbiologywitharpan yes why not your video is very nice I will shere your video kip it

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Super awesome ❤

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khub valo

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Where can you find these slides as these are not availabel on insta

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its not anymore avilable for free. you can buy @5$

[@dr.rajnarayanyadav5761]

Good video

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From Bangladesh ❤

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Which test book

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How can i get this notes ?

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@@aestheticfooty we are making these notes it would be available soon. but these videos are like notes. watch it several times.

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@@animatedbiologywitharpan 👍 upload soon, btw thankyou

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thanks sir

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Is this video useful for net exam ?

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Of course......its just not tagged as csir net prep video. But these kind of detailed video is important for deeper understanding.

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Sir are you from dubai

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nope

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Total english bol rhe h thoda hindi hona chahiye na 🥺

[@animatedbiologywitharpan]

I am a Bengali, don't speak Hindi well.