Are All Calories The Same? What The Fitness EP 35

[@Deciden0w.]

There should be a show where Layne would debate some of these so called "experts" on TV every day. That would totally make the world alot better

[@bart-kay]

I've invited him to debate me a number of times, he lacks the courage. Because he knows he'll get shown up... like this: kzbin.info/www/bejne/ZojQqYuOgrqEos0

[@IsaacWendt]

Layne, just keep doing this, I know the videos are short and you really don't get the appreciation you deserve but these small nuggets and your massive reference of studies are extremely helpful for someone like myself. Thanks again.

[@peetos-chan2835]

It's so crazy how much effort it takes to find Truth.

[@adrianm.1732]

The calorie is a social construct therefore a calorie can self identify as it pleases!

[@davidpeters7447]

It’s a circle per Dr Greg

[@DiaJasin]

@@davidpeters7447 NOT A DOCTOR!

[@Buddy330]

Self identify HARDER THAN LAST TIME!

[@davidpeters7447]

Dia Jasin buy his cookbook!!!!

[@dang1099]

The calorie is literally from physics and it's an amount of energy...God our education system has failed us.

[@elegantwave3952]

Agree about low/high sugar diet , you can lose weight on both, but i avoid sugar cause of dental health , skin and so ... i consume it , but limit them :)

[@dietgainz7951]

the value of your videos is insane,literally life changing informations all the time!

[@Dezi002]

Layne, stop making so much sense, this is 2020, the year of delusion.

[@BlargeMan]

Someone should write a modern cover of Land of Confusion specifically for 2020

[@cookinthekitchen]

I believe dr Lustig is exactly right about insulin resistance being the dividing factor between having diabetes or not having diabetes. The reason why athletes often do not have diabetes is because exercise leads to insulin sensitivity.

[@lillijstein1321]

I'm so deep into these videos and I've left no comments for the algorithm so here's my comment to say you're 1) making my dear WFH side-job bearable, 2) effectively getting me jazzed about science, and 3) giving me confidence that... I'm doin' ok! :)

[@StevePhillips76]

I enjoy the educational videos, but I really look forward to Friday because of what the fitness videos! Thank you!

[@josephdavey2342]

Hey Layne, I asked a registered nurse about the Liraglutide drug (there must be a TON of different ways to pronounce it, I was worried it might have even been the wrong thing) and she said this (would like to know your thoughts, I agree with you and most importantly, the current data btw): "Liraglutide works because it also blocks the production of glycogon break down in the liver. It has the effect of causing delayed gastric emptying which often causes a reduction in intake for patients. It is likely the reason for increased weight loss in patients. I still see more than enough evidence in my everyday practice as well as plenty of studies and literature to believe insulin is the key factor in weight gain. Prescribe insulin, weight increases. It won't matter what diet exercise or support we give, with enough insulin over time, weight increases. Drugs that lower insulin result in weight loss regardless of their effect on blood glucose." I am willing to bet that "reduction in intake for patients." is the reason it works lmao...

[@doctablademd]

Yeah reduced gastric emptying and reduced appetite play a bigger role than the minor short term stimulation of endogenous insulin with that drug. Insulin is an anabolic compound and if someone is insulin resistant they are pretty much always hyperinsulinemic we just rarely test for it. The quickest way to adjust for that is to reduce their carb intake which wasn’t exactly coming from fruits so arguing against the insulin hypothesis is just laughable when as a doctor we can directly see what happens, when we put people on a reduce carb higher fat and protein diet their diabetes and cravings for sugar reduce, when we give them insulin and let them continue to eat whatever they want they just get sicker fatter and die faster.

[@Ryan_DeWitt]

I like the way you explain things. I have learned a lot about nutrition from you. Keep up the work. I've also used your videos to debunk peoples BS.

[@_nishantk_]

IMO, I agree with Dr. Robert Lustig on the effect of Fructose on body and it’s addictive nature, fructose in the fruits come with added fibre which makes you satiate and prevent overeating, however fructose in the processed food is devoid of any such complementary thing so we tend to eat more, but on the other hand I agree with Layne on calorie in and calorie out as that is basic thermodynamics, you need to be in calorie deficit to lose weight and by extension fat. One other thing Dr. Lustig is saying fructose, which does not mean all carbohydrates, for example wheat, rice, potatoes, sweet potatoes they are carbohydrates too but don’t have fructose. If we look at the east asian cuisine they have rice as staple but they are not overweight, mainly because they consume less calories as a result of fibres in their food and less addictive effect of fructose. We can also look at the example of Mexico, where the introduction of Coca Cola has made the population obese, high amount of sugars, more addictive, more consumption

[@himesjon]

Exactly and Layne doesn’t address that or any other evidence he does site.

[@stevecarter3821]

The girl nailed it on her opening statement.

[@dr.joaquindelcastilloalvar7317]

Can someone please share the name of study Dr. Laynes referring about 100 grams vs 10 grams of sugar daily, with protein and fat equated on a calorie deficit 🙏

[@Torcsen]

I think some foods will elevate insulin over a longer time than other foods. Same amount, but with a longer impact is what I been told.

[@mattimatta]

Whey protein and beef have the same insulin response as eating white bread? at 09:58. That does not make any sense at all. Beef has zero carbs in it... Can you provide a source link for that statement?

[@DrHollyFields]

I loved your comment about exercise and eating more- I am looking at this research for my dissertation specifically related to strength vs cardio and eating choices in middle aged women (relation between the two)

[@donnahalstead531]

Sounds like it’s all about insulin resistance causing disease which can be caused by too much carbs or fat?? We need to lower intake of both but increase protein which is probably what’s missing in most people’s diets

[@shayhubfit]

I tried clicking on the link to your nutrition course and it says the page could not be found.. I’d love to check it out.

[@JonnyVmagic]

Layne, can you cite a source that shows that beef raised insulin as much as white bread? Everything I find shows that beef raises serum glucose and insulin minimally compared to other foods. Also, if what you are saying about saturated fat -> higher LDL -> atherosclerosis, why haven’t any randomized controlled trials shown a difference in atherosclerosis with increases in saturated fat consumption?

[@bradwhitchurch3147]

Appreciate the breakdowns 👍

[@harku123]

I need more biolayne in my feed so here I am boosting the algorithm

[@TheSoyestToEverSoy]

That women with the PhD is like, "I knew this guy was a fucking zealot, but at least I get paid for even sitting here".

[@donaldbangart563]

It's easy to poke holes in the whole sugar raises insulin thus causing insulin resistance theory. I'm sure you have heard of this new(ish) theory of high pufa(linoleic acid) as the main culprit of insulin resistance. I would like to hear your thoughts on this theory. maybe next friday

[@nickferraro7295]

if you go to the account @thenutritionaladvocate on insta, you can find Alan Flanagan, a guy who Layne has collabed with previously and has a whole series of posts dedicated to the PUFA/Omega 6 topics that are very insightful. Idk if or when Layne himself has spoken on this theory

[@shellderp]

I'd like him to talk about it too. My guess is high pufa intake is associated with fast food and it's a correlated increase

[@Sharkyktc001]

How exactly does one measure 'death/years of life lost due to sugar consumption'? I doubt any coroner's report has ever listed '2L of cola per day for 30 years' as a cause of death

[@taylorforester88]

When I say I almost crumbled under weights while squatting because that .5 second clip of the X-Files theme got me laughing at the BOTTOM of my rep 😅😅

[@pelonete5000]

will love to watch a debate between Layne and Robert Lustig.

[@thepurplebox380]

In the world of nutrition the colloquialized word "1 Calorie" (1 Kilocalorie in physics) is defined as: The energy needed to raise the temperature of 1 kilogram of water through 1 °C. The energy required to heat up water doesn't change based on the source of the energy ¯\_(ツ)_/¯ Q for Llayne: When we say that protein has a higher TEF than carbohydrate, why do we say that both give us 4 Calories of energy? Why not just say that protein is 3.8 Calories and carbs are 4.2? Is it just convenience or is it such a negligible difference that we don't care?

[@ww2fitness]

It's actually because when we calculate we've already accounted for the difference, 1g of protein actually has about 5cal but we need about 1cal for the TEF of protein

[@arnoldschwarzenegger3744]

@@ww2fitness if we have already accounted for Protein's TEF then why do we even consider it's TEF ? In a bomb calorimeter Protein gives 5.2ish kcal/g but physiologically Protein gives 4kcal/g (As 1.2ish gets used as TEF) Considering this, If I consume 100kcal from protein (i.e, 25g of protein), I will still get 100kcal right ?

[@ww2fitness]

@@arnoldschwarzenegger3744 personally I don't further account for TEF from there. It's not something most people even need to understand

[@hunter_69_69]

Dr. Ludwig seems to be doing science backwards: Only discussing data that fits his hypothesis, rather than changing his hypothesis to fit the data.

[@Marta1Buck]

layne: enjoy the tasty cherry picking

[@Seda1979]

Agree

[@choboruin]

I first saw you on Joe Rogan and always show you to my friends when I argue that we know nothing about the human body and that everything contradicts itself thank you.

[@FaridEmame]

I've been binging for weeks now om your content. I unfollowed deflauer, berg and some others. When you mentioned Neil D Tyson I already knew where your head was at lol. 5 weeks of listening I've already changed my whole approach to CICO and I've seen more improvement in this time than last 5 months. Truly appreciate you. Looking for a video of Thermogenic effects of food and are there really any foods with a negative thermogenic effect like brocolli? Appreciate you sir you are truly elite in this lifestyle.

[@superdvd5]

Please provide a reference for "liver glutatide" (sp?) at 12:16, can't find this anywhere... Ahh, he's talking about GLP-1 mimetics. Well, weight loss on these is tied to the fact that GLP-1 reduces appetite, so weight loss is achieved *in spite of* increased insulin

[@thegripguy9696]

there is a slight variation is that different calorie types have different thermic effects, fat being 2%, carbs 10%, protein 25% and fiber 50%, which makes it so in a sense, 1g of fat has 8.8 calories, 1g of carb has 3.6 calories, 1g of protein has 3 calories and 1g of fiber has 2 calories. it is also shown that starch&Glucose have better metabolic effects than fructose or lactose. but beyond this there is no difference based on processed vs not. the only other thing worth noting is that most packaged foods state that they have 10-20% fewer calories than they really do since the USDA allows a 20% error which is one of the reasons some people make false conclutions(like thomas delauer) about calories in processed vs not foods.

[@pattybaselines]

We are all aware lol

[@bluntfitnessandhealth]

Calories are just measurements of energy, but not all are processed the same 💪

[@Plankyoutube]

Super Troopers is great, Iv not watched the new one yet!

[@godsgiftto3arth]

i like that i learn so much from these.

[@petrfilinger9205]

Love your stuff despite you not confirming my bias:)))

[@alecazam6931]

Quality content as always! Great video brotha 🤙🏽

[@peetos-chan2835]

Much appreciated 👍👍

[@thomasmurphy6652]

A lot of big words sounds pretty cool though

[@danielapetrova3416]

Do you have any videos how to calculate how many calories will be alright to consume per day?

[@tommycollins5302]

Your question is a little unclear to me, but hope this helps: Do an internet search for "TDEE calculator". This will help give you an estimate as to how many calories you would need to maintain your current weight. Only through trial and error, can you determine a closer approximation(adjust calories as necessary). Note: 3500 calories=1lb of fat=500 calories/day. So, to lose 1lb/wk, one would need to be in a 500 calorie deficit/day. And vice versa, 500 calorie surplus/day to gain 1lb/wk. When losing or gaining weight, it will likely be more sustainable if you lose or gain at most 0.5lb-2lbs/week depending on current body fat level. 'MyFitnessPal' and 'CalorieCounter by FatSecret' are good apps to track calories.

[@chucklandry73]

Agreed. Infinite calorie consumption leads to all sorts of health disasters.

[@KineticSymphony]

I don't see the connection to the plant-based world, the literature itself is aligned with (some) of their claims, very strongly on saturated fat, cholesterol and atherosclerosis progression. But, that's a huge one. And yes, the governments of the world / medical establishment don't set a baseline LDL at a level where Atherosclerosis ceases to progress, because they view it as unattainable for most. Which is sad, because most (baring unfortunate genetics) can indeed attain it. I for one do not want to die of cardiovascular disease when I'm older. One thing is true however, it's not about being plant-based or keto or carnivore, demonizing fats or carbs if we're talking exclusively about weight loss or weight gain. Equate net calories absorbed and weight loss / gain will be identical.

[@artursrikmanis]

Layne, I was wondering, If food is not digested well, does it also mean less of the consumed calories are stored in fat if you're in kcal surplus? Thank you, awesome channel!!!

[@AnotherFancyUser]

I would imagine you poop it, still needs to see the video, for example fiber (if im not mistaken) cannot be consumed, you poop it.

[@ScienceUnbiased]

@12:14 I think you mean liraglutide - it DECREASES food intake (it alters hunger queues in the brain) and it also partially inhibits secretion of glucagon, decreasing hepatic glucose production - both which would favor a loss of weight. Sad to see a higher dose version marketed strictly as a weight loss drug (Saxenda) which has a retail price of over $1500 per prescription and safety issues such as thyroid & pancreatic cancer... taking it WITH a prescribed calorie restricted diet the average weight loss is 18 lbs/year vs 6 lbs on diet restriction only. Boggles the mind that anyone would pay that much & increase cancer risks just for the possibility of losing an additional 12 lbs in a year.

[@ScienceUnbiased]

@Christine Connell I think it has a much better safety profile, oddly can provide significantly more weight loss over the course of a year & is available as a generic for less than $15 per prescription. Suppresses appetite though effect usually wains over time & shouldn't be taken more than 90 consecutive days without a break. Personal observation, can cause slight jitters followed by a loss of energy as the the effect wears off later in the day and cotton mouth is pretty common. Drinking a gallon of water daily divided throughout the day (you don't want to drink much too close to bedtime) can help with the dry mouth. If you between meal snack, if you can think of a low carb whey protein shake a snack, drinking approx 25gms by content shake will not only help stave off hunger, it will help protect muscle so more of your losses are coming from fat. (there ARE good tasting whey proteins out there, so you can enjoy them as snacks) Good luck.

[@JohanFitFoodie]

Totally love these 😁

[@URFIT]

Nice outro. Keep informing

[@kxs7267]

Late to this but thought I might also mention: the list of "most obese" countries is a bit unexpected (certainly was to me), so I'm not sure how valid his obesity v. diabetes comparisons are. I was shocked how high India is on the obesity list - which actually tallies with it having a high diabetes rate. Plus, it's quite well recognised that Indian populations wherever they live tend to suffer diabetes at lower BMIs than other genetic populations. Would definitely want to check the numbers before accepting his comments in that part of the video...

[@nolimitsfitnesscoaching1223]

I love it when you help to stop these idiots from spreading false info. From all the REAL trainers out there, I thank You!

[@tylermccollum5540]

I just love how you cut thru the bullshit. It makes my day just a little bit better and it makes me wanna believe in humanity just a little more...if only slightly.

[@narendrasonkar2388]

Isn't low lean/ muscle mass due to less total overall body mass one of the reasons why people in those countries still can have diabetes irrespective of obesity ?!

[@dannydettwiller9894]

Layne, you gotta debate this guy (Lustig) one on one, bro. Please.

[@theswingmechanic]

I fn love you, layne!

[@weejonan]

Layne, please never stop being you. Its literally the best thing to watch is you loosing you shit. Plus love learning from yi bud.

[@bmansour19]

Layne, I’m still confused why CICO applies when different sources of calories (protein, fat, carbs) have different effects on the body. So if I eat 100 calories of sugar it takes less energy for my body to metabolize than protein, so I’ll have more calories “left over” to store as fat, or burn or whatever. Is it just that the thermic effect is minimal and doesn’t affect weight loss significantly? Sorry if I’m oversimplifying

[@davidpeters7447]

Protein 100 calories in, 20 calories out for the body to digest it. Still CICO.

[@fech]

@@davidpeters7447 Then, calories are not the same because if you eat protein, the usable calories is only 80. If you eat fat, the usable calories is 95.

[@mickdungeon602]

I wonder what the caloreis in a litre of coke are. Asking for Farva

[@ssalomass]

Please, post the reference of the papers you mentioned.

[@mariannahuth7502]

Layne:white f****** bread Greg: regular ass bread

[@skateata1]

I do think I would be in better health if I didn't eat high sugar foods simply because they are usually high in calories and fat.

[@shinsplintandre]

It seems like these are two different levels of the same point... Layne is at the 40kft level and Dr Lustig is at the ground level. I think without a doubt the idea of "energy in" greater than the "energy out" theory holds true, but that's the totality of the issue. It's not examining the cause of why the energy in is so much higher than energy out. It doesn't examine sugar's effect on satiety, metabolism, adipose tissue regulation, etc. It would be similar to saying that the problem with abject poverty is that there is an money imbalance; if you want to get wealthy you must make sure that your "money in" is greater than your "money out". It's true, but an overly simplistic and non value added view that ultimately doesn't address any root causes of the poverty.

[@biolayne1]

That is NOT what he’s saying. He’s saying on a biochemical level that these calories cause more fat gain than other calories.

[@shinsplintandre]

@@biolayne1 Interesting. So as a non PHD non-biochemist with a simplistic engineering background, I would pose the following question: Could the macronutrient content of the calories consumed be a mitigating factor in the relative difficulty or ease of the reduction of fatty tissue mass? I feel like this is the real heart of the matter, and would certainly fit with my classical thermodynamics training.

[@dartfather]

@@biolayne1 That is also true. If you drink 2000 calories of oil, it will cause you to get fatter than if you drink 2000 calories of alcohol. Remember, you are drinking exactly the same amount of calories.

[@johnsmiff8328]

Hey Layne, what do you think of the handful of studies that indicate that muscle mass is protective against insulin resistance? Even if their model were accurate, shouldn't the low carb crowd just be lifting?

[@noahbatz6006]

Thanks buddy

[@Jannas84]

The guy Layne is critiquing was just on Andrew Huberman's podcast making the same claims. I know Huberman has had Layne on before. I think it's time for a moderated debate between the two. I'd pay to see it.

[@pattybaselines]

Please do a video on John Jaquish...someone has to :(

[@otega9571]

I think you misunderstood, and have thereby slightly misrepresented his argument, a calorie of complex carb contains complex glucose chains, simply carbs on the other hand, contain just a bonded glucose and fructose molecule, the fructose has to be converted to glucose in the liver, a process that isn’t required for a complex carb which is without fructose. That is one difference btw a calorie of complex carbs, and a calorie of simple carb/sugar. As you mentioned, the varying characteristics of the source of the calorie, varies the effect of the calorie, e.g satiety characteristics, hence the saying that calories differ. Please correct my opinion with facts, I am eager to learn. His argument is that, excessive consumption of simple carbs (not complex carbs), could increase chances of some cancers and dementia.

[@nekkon1989]

What about different sources calories and the Results on body composition. That would be an interesting topic

[@atim99100]

People in India and China have lesser muscle mass and mostly come under skinny fat category , even with normal weight their body fat percentage is very high and hence more type 2 diabetes.

[@graeme5060]

I used to believe this was due to insulin resistance. Induced mainly from a diet high in simple carbs. Now I'm thinking it's perhaps just genetics in combination with a less than ideal diet. What do you think?

[@lootensstieven]

Hey layne , anaother video suggestion. What the hell is the upcoming bullshit with the "magic " chicken stock /bone brath. Another bullshit hype just to add extra calories?

[@mgreenester]

What are hyperpalatable foods? Would you please please clarify what you mean by this term. Should we only eat bland foods?

[@ScottishAtheist]

Junk foods designed to be as tasty as possible to the taste buds. Crap from a nutritional point of view. There’s plenty of foods that are both tasty and healthy.

[@xperimental9860]

Sir Hope these clips are on Twitter and Instagram also

[@rogere5585]

So...glycemic index?

[@eranstrauchler2831]

Thank you Layne for falsifying these carbohydrate conspiracy theories!

[@reidcox4542]

Yes

[@sunkthebirdie7082]

Beef has half the insulin index of white bread. Totally objectively false to claim otherwise.

[@pvpmartins]

Calorie is not a calorie. Aristotle screams real hard now.

[@HerrFinsternis]

Nice rebuttal :)

[@Marta1Buck]

I can hear "is he, in fact, breaking the law of thermodynamics? NOOOOOOOOO!!!" inside my head. help.

[@RocnRed9]

He’s a MOOOORRROOOONNNN!!!

[@candied.crabapples]

And “ARE YOU FREAKIN KIDDING ME??!!!”

[@mikiristic9297]

for a next what the fitness do this.... OCCLUSION TRAINING. video link below, idk where to submit these links besides yt comments.. kzbin.info/www/bejne/sGa8oaxjl7iWpLM

[@soaringgrasslands3148]

uhh. layne. hes talking about sugar. Youre conflating it to just carbs in general. Lustig has stated he is not a low-carb guy. And even did an experiment at his University in which they fed people a processed carb diet with no sugar. Compared that to a diet that was high in sugar (calories equated). Metabolic markers improved just from having no sugar, once again, calories are equated.

[@xxdrowssapxx1]

i have watched a lot of his stuff. He is actually a low carb guy. He went to a low carb conference recently. He has on occasion also conflated sugar with carbs although not on purpose. At this point, lustig is no longer neutral. He has built the last 10 years on a anti sugar and in some cases, anti carb tirade. He has done good work, but he is now getting a bit out there. He is trying to absolve saturated fat and blame fruit for some problems. To the point people are scared of fruit. In the minds of many, the logic has become, fruit has fructose, therefore fruit = coca cola. The consequence? Those who don't give two shits about health finally have an excuse to eat like crap. The other agenda that he has stated time and again is with refined carbohydrates. The consequence? People are now scared of rice, bread, pasta and potato. That has in part paved way to the intuitive eating movement, which is so terrible that most healthcare professional have a heart attack. Having said that, no healthcare professional in their right mind thinks sugar is in anyway good. However, as free living individuals, we should not be made to feel morally inferior for eating for reasons other than physiological ones. It is one thing to eat carbohydrate and be informed about it's effect. It's another to treat it like a toxic substance. Sure, cut down if you can. But avoiding it at all quantities at all costs is quite insane. He should have promoted the eating of whole food as his main message, instead of going down this stupid rabbit hole. Because you know what this ultimately leads to if we take his suggestions to their logical conclusion? We are going to basically dump 75% of our food supply.

[@pattybaselines]

Layne cited studies on the effects of sugar as well.

[@Reppintimefitness]

Facts bro 💯

[@jthuff5102]

the most well understood principle of the universe is the conservation of energy therefore calories in and out is the most well understood principle of fitness. anybody who says otherwise is a liar. however having said that highly processed sugars causes lethergy which effects your calories out A LOT cuz a bro don't wanna work.

[@NickD25]

If it's not calories in/calories out, why do weight loss surgeons lose their time doing gastric bypass to.... wait for it.... reduce caloric intake?

[@chucklandry73]

Think of it this way, If you take the tires off your car and drive to work, will you still get there? Yes, you will but with tons of damage to your vehicle and also the road. What's more you will have a lower quality ride on the way bumpin and grinding all the way. But you will still get there correct? It's not just the destination of fat reduction but also how you got their that can make a difference in your overall health.

[@NickD25]

@@chucklandry73 I'm in no way arguing the point that what you eat has an impact on your health and on what your body composition will look like. What I'm saying is that no one would be overweight or obese if they were following their caloric intake. And the fact that the number one surgery to reduce body weight in obese patient is gastric bypass tells the whole physical story of why a person is to that point. IMHO and by experience, I know losing weight is way more psychological than physical and that's something not often discuss.

[@chucklandry73]

Agreed...people eat waaaaay too much! But consider all these lame anabolic cookbooks even if they are at reduced calories or calorie deficits for each individual... They are probably way too carby for your standard individual who isn't athletic. I believe it can be harmful to those folks and that's another pet peeve of mine.

[@ericgraham3506]

After I watched this guys video as well I don’t think he is just talking about carbs but more the type of carb. In this video he was speaking at a no carb event where he didn’t necessarily attack carbs or vegetables but more actual sugar consumption. I think the study they did on kids was pretty good. The video is kind of long but the stud on kids was pretty interesting. Please do a response on this video attached Layne. kzbin.info/www/bejne/oKGxhmpomdOsaNU

[@Barbie_All_The_Way]

Without have the genes for it, Can you get type to diabetes when your malnourished? Without the genes. I REALLY want to know this TOO. Someone please comment AS SOON AS YOU SEE THIS POST PLEASE PLEASE PLEASE 🙏🙏🙏🙏🙏

[@greg_levine]

5:08 Layne is so smart that his opinions are facts.

[@VillainMcKillin]

So according to this other doctor we’re basically all going to die. Oh wait.

[@BeztFitness]

It’s not a new super troopers it’s a new Reno 911 lol 😂 I thought the same thing

[@snakethejake9474]

That's a weird question to ask. Feels like a clickbait. It's like saying, are all pounds the same? Are all kilograms the same. A calorie is a measurement of a unit.

[@ryanfollweiler691]

Great, a medical doctor telling people it's okay to be obese. How do we fix this shit?

[@Leoparavivir]

Layne: any chance you can talk about a whey protein named immunocal? In my country they are selling it like a health exilir. Thank you.

[@VernCrisler]

Lots of obese people who don't have T2 diabetes. Now they're almost wishing for T2D so they can get the GLP / GIP medications.

[@NotMyRealName1]

Lol “he’s setting up a strawman” whilst you set up the biggest strawman

[@rodiusmaximus]

Yes all calories are the same. But a calories is not the same as a Calorie.

[@deadastronaut2440]

Icelanders also have a mutation that shelters the population from type 2 diabetes.

[@Mezog001]

I would love to hear you talk about body composition and weight and the type of desieses people get.

[@bryceaxelrad3467]

Dude explain your logic for me here. Is 100 calories of polyunsaturated fat the same as 100 calories of saturated? Or 100 calories of sugar without fiber? Your logic here makes no sense at all.

[@SirAlexanderdeLarge]

The truth is out there... Food is killing you!! Quit all food altogether and lead an ethernal, disease-free, illuminated life! 🤦🏻‍♂️🤦🏻‍♂️🤦🏻‍♂️

[@SirAlexanderdeLarge]

@Chokwe unbelievable that's even "a thing"... What have we come to! Human race never fails to disappoint.

[@shellderp]

I mean it's pretty deceiving to say calories are the same when it changes how you burn energy. How do you explain this study for example in mice, where mice ate the same number of calories but those with more linoleic acid gained more weight? www.ncbi.nlm.nih.gov/pmc/articles/PMC6700518/ >1%LAG and 8%LAG‐fed mice consumed similar numbers of calories, but yet 8%LAG fed mice were heavier (Figure 1B). Interestingly, 1%LAG‐fed mice consumed significantly more total calories than 8%LA‐fed mice (p ≤ 0.01) yet had similar body weights

[@TheFallibleWarrior]

Seriously...mice? You can find studies in actual humans that would be more representative. When you equate total calories and exercise...bw/fat loss is similar. Pretty easy stuff to find.

[@dartfather]

@@TheFallibleWarrior what would make you fat...2000 calories of oil or 2000 calories of alcohol?

[@lakshyasingh3006]

Excellent video. Dr. lustig can come off as a conspiracy theorist but i don't find your criticism completely justified. 1.Protein raises insulin but it also raises glucagon simultaneously (unlike refined carbohydrates) . 2.The increase in GLP-1 does help improve biomarkers because it helps shove the excess serum nutrients into cells or other tissues (insulin isn't the problem, insulin resistance is). 3. The carbohydrate insulin model of obesity isn't the ultimate explanation for diseases of civilization but one of the major contributing factors to modern chronic disease. 4. When he says "a calorie isn't a calorie", he obviously knows calories are just a unit of heat but wants to address it to CICO zealots for oversimplification of the really complicated science of metabolism. Just my two cents.

[@chadrandazzo2305]

That can be the problem with discussing mechanisms - they don't always have this slippery slope effect like Lustig is trying to explain. The outcomes are what is more important. There are no tightly controlled studies in scientific literature that prove that when calories and protein are equated, insulin and carbs directly cause those things. If that was the case, all ultra marathon athletes who carb load up to 10-12g carbs p/kg of body weight 24hrs before a race would have type 2 diabetes (for me at 88kg, I would consume >900g carbs the day before a race, but I've never had diabetic blood markers or metabolic syndrome. It is the opposite as they aren't gaining weight, they are topping up their glycogen stores for glycolytic energy fuel. Just look at Lustig's other claims and all the anti sugar propaganda films he's appeared in. He tried to cite his own study with confidence done on children with metabolic syndrome after they consumed high sugar meals. It wasn't controlled and didn't even watch them consume meals - he gave it to them to take home! He's a total quack.

[@lakshyasingh3006]

@@chadrandazzo2305 Agreed. he didn't have a control group for that study. A new hypothesis for obesity has emerged with excess PUFAs as well. I think it's the combination of refined carbs with PUFAs driving metabolic mayhem and not the CICO model.