Are Seed Oils Inflammatory?! (The *Evidence* No One Shows)

"Seed oils are inflammatory!" according to every blog and podcast. But what does the science say? The evidence on 9 different seed oils, heated seed oils and genetic variability. A complete look at seed oils & inflammation and all the evidence you were never shown.
Are seed oils inflammatory?
1. seed oil on inflammation
2. Heated seed oil
vegetable oil is inflammatory? Only seed oils are inflammatory? Depends on omega6s, Linoleic acid?
flaxseed oil not inflammatory. omega3 rich, can be anti-inflammatory
canola oil: CRP didn't change
saturated fat vs omega 6s. replaced saturated fat with unsaturated fats (canola and sunflower). no change in inflammatory markers
one trial compared canola to olive oil, found a reduction in CRP on both canola and olive oil
similar to flaxseed oil. anti-inflammatory?
~1tbsp sunflower oil daily. refined oil, treated with chemicals and heated, not cold-pressed. no significant change to CRP
“n-6 PUFA may act as anti-inflammatory”
Connect with me:
Facebook: / drgilcarvalho
Twitter: / nutritionmades3
Animations: Even Topland @toplandmedia
References:
www.mdpi.com/2072-6643/8/3/13...
www.sciencedirect.com/science...
link.springer.com/article/10....
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/27737...
www.ncbi.nlm.nih.gov/pmc/arti...
www.sciencedirect.com/science...
www.sciencedirect.com/science...
www.nature.com/articles/s4143...
academic.oup.com/ajcn/article...
pubs.rsc.org/en/content/artic...
academic.oup.com/eurjpc/artic...
www.ncbi.nlm.nih.gov/labs/pmc...
pubmed.ncbi.nlm.nih.gov/16351...
academic.oup.com/jn/article/1...
reader.elsevier.com/reader/sd...
academic.oup.com/jn/article/1...
pubmed.ncbi.nlm.nih.gov/19234...
lipidworld.biomedcentral.com/...
www.tandfonline.com/doi/abs/1...
pubmed.ncbi.nlm.nih.gov/23506...
www.sciencedirect.com/science...
link.springer.com/article/10....
www.sciencedirect.com/science...
www.ncbi.nlm.nih.gov/pmc/arti...
link.springer.com/article/10....
pubs.rsc.org/en/content/artic...
www.thieme-connect.com/produc...
academic.oup.com/ajcn/article...
www.sciencedirect.com/science...
onlinelibrary.wiley.com/doi/p...
academic.oup.com/ajcn/article...
www.sciencedirect.com/science...
www.sciencedirect.com/science...
pubs.rsc.org/en/content/artic...
www.sciencedirect.com/science...
www.tandfonline.com/doi/abs/1...
www.sciencedirect.com/science...
onlinelibrary.wiley.com/doi/a...
academic.oup.com/advances/art...
www.ahajournals.org/doi/pdf/1...
pubmed.ncbi.nlm.nih.gov/21663...
www.ahajournals.org/doi/pdf/1...
academic.oup.com/ajcn/article...
Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.
#NutritionMadeSimple #GilCarvalho
0:00 Are seed oils inflammatory? Intro
1:36 Schools of thought
2:06 Flaxseed Oil
3:35 Science, Variability & Perception
6:00 Canola Oil
8:02 Sunflower Seed Oil
10:36 Sesame Oil
11:14 Soybean Oil
12:52 Corn Oil
14:00 Hempseed and Grapeseed Oil
14:31 Safflower Oil
15:42 Dose
16:52 Time
18:36 Acute changes in gene expression
19:45 Whole sources of fat
20:33 Heated Seed Oils
24:51 Summary
25:38 Seed Oil vs Junk Food
26:03 Funding
28:01 Biochemical mechanisms
30:42 Genetic variation
31:28 Dietary choices and emotion

[@garyloewenthal]

I would like to see a study on whether comments about seed oils are inflammatory. 😊

[@NutritionMadeSimple]

comment of the day

[@carinaekstrom1]

They can lead to pretty painful inflammation, it seems, but It would be great if the evidence based comments are the most infectious.

[@longlostcoder6322]

​​@@NutritionMadeSimple find this interesting because, my husband eats so healthy, like basically Mediterranean diet with olive oil only. And I don't. Before we were together he was super healthy. I stirfry and deep fry alot with - canola oil and soy bean oil. I smother things in kewpie mayo; I eat Karage and katsu ect. In fact the healthies thing I eat is nato. He's black and I'm Japanese and white. My diet was literally killing him. Is it possible that it's inflammatory for black ppl? His LDL and HDL are so high and mine are all in side of the normal.

[@GIANTWOODS]

😂😂

[@oirampeceda2409]

​@@longlostcoder6322maybe not because he's black, but maybe something unique to him?

[@junktionfet]

Stumbled on this video today and I'm so glad I did. Thank you for keeping the principles of science alive and for doing all of the work compiling these studies. I wish there was more of this out there

[@cloudninetherapeutics7787]

Excellent presentation. I appreciate how thorough your research is on this. Like many who are dealing with inflammation I'm making healthy choices and always learning. Keep on with your work, this is great!

[@alicemonsell1352]

Thanks for filtering thru all this research, very enlightening! Love your "no opinion" attitude. No drama! Refreshing and clear.

[@angeljuliedr]

I have been into Immunology, immunotherapy and recent 7 years gerontology and metabolic therapy Research work in Asia. Total of 18 years. We are currently looking at the Japanese diet and the new "Green Zone" of the pool of southern China centenarians. Similarly with rice and grains that have "new" rice or "old" rice, seed oils production and expiry date do contribute to its oxidation and rancidity impact especially in tropical S E Asia. The shelf life after opening the bottle is crucial in terms of using the seed oils for clinical trials. All these trials will start with a fresh new bottle. Individual consumption at home for casual stir-frying or deep frying means the bottle of oil can last for a few months. Rancidity if mild cannot be easily detected by an average person especially so if they are senior or elderly (slightly impaired smell and taste). Dining out has also one risk of having adulterated seed oils that are not fit for consumption. Traditionally, the Japanese 1000 years ago did not use seed oils but mostly boiled their foods using soup based cooking methods. Thank you Gil 👍💓👏for your indepth research and awesome contents. Personally, moderation in consumption and buying and storing small bottles (not large) are my advice to those who stlll want to use seed oils. 🥰

[@rokzane]

That's an argument for storing them properly and not buying more than you can use within 4-6 months. If they are stored in a dark, cool place, the oxidation is much slower. Under refrigeration, you get almost double the shelf life, and some under refrigeration (like nut oils, sesame, and canola) can last 2-3 years.

[@jassy0903]

I'm a nutrition student and you're blowing my mind. Thank you for focusing on inflammation alone in this one. There is a lot of misinformation out there for sure!

[@helderduarte213]

You should check the amount of persons used on those trials. Kind hard to come to conclusions with such a few sample on all of those studies.

[@destro1989]

There are like 20 studies there. What more do you want? If you you use massive samples then youll start whining its epidemiology. ​@@helderduarte213 its embarrassing. Just accept you're biased.

[@clarkeeeee]

I appreciated your careful, balanced approach. You're the first person I've found on the subject who took a fair look at each perspective and came to a fair conclusion without condemning anyone. Thank you! 😊

[@geas989]

Amazing content, produced by hard work. Its a shame you dont get the recognition you deserve, your videos could help a lot of missguided and confused people.

[@MrJoker74]

Very interesting and thorough video. Going through all these articles on the subject must have taken some time :) That someone goes through the actual research without prejudice is nice to see. Looking forward to watching more of your videos!

[@NutritionMadeSimple]

this video was a couple years in the making... :)

[@1996sarvesh]

@@NutritionMadeSimple Unbelievable

[@irfanm5892]

@@NutritionMadeSimple 😮

[@alexl2371]

I always told people that gut issues has been researched decades ago and I knew the root cause is from conflict shocking stress, foods has nothing to do with it...if anything, the most dangerous foods to put in your mouth today is vegetables because of glyphosate, bill gates and his boys buying out the fields to grow more poison for our guts to get sick from this poison so we can than medicate with his prescription drugs..buy organic or preferably from farmers market

[@Kyle906-Q8]

@@NutritionMadeSimple omg!! Your amazing!

[@dubfire77]

Excellent work as always! The only thing it was covered from my perspective was organic vs. conventional oils, in case there are this kind of studies. I hope this video has a follow up regarding the consumption effects of different types of oils on cholesterol levels.

[@deanmorelli783]

I love your honesty. Most of us simply want to manage our health. Getting clear unbiased information not influenced by current food fashion is sometimes hard.

[@debravictoria7452]

IKR. Remember when they told us to switch to margarine from butter?

[@pinkpig8091]

You do like an entire lit review for each video, I’m in awe ❤️

[@maryclarence6429]

Thanks for a great video. I'm always impressed with the quality of research from this channel and the skill in communicating to a general audience. This is the best channel on nutrition hands down. Wish there were more channels with this level of quality for other areas of health.

[@applerunner1184]

I am a recovering “youtube low carb influencer” watcher and your channel is helping me get off the wagon with facts!

[@espenstoro]

Been there. It's very convincing when someone with a doctor title talks nonsense to someone like me who doesn't have this kind of education.

[@JoeARedHawk275]

@@espenstoro I’m pretty educated on biology (not on nutrition though) and even I was fooled by low carb for a while. However I noticed that there were no improvements on it, so I started researching. It’s a shame how many people believe in keto and stuff. I wonder how many total years those influencers have reduced peoples lives by.

[@leetpg]

@@JoeARedHawk275 are there studies to show a low carb diet shortens life expectancy?

[@ChadRD]

@@JoeARedHawk275 many people have great results on low carb diets so I don't know where you are getting that there are no improvements

[@daniellove162]

Low carb or no carb? As a diabetic who wears a constant glucose monitor and doses insulin accordingly I can tell you insulin resistance is real and having a low carb diet keeps my insulin working very well. I’d say a low carb (not no carb) diet after 40 is essential.

[@darkmagiciansorn]

Just wanted to pop in and say thanks for the videos you’ve made and are making. It can sometimes be hard to discern truth from fiction especially when many of us don’t have a background in a medical field. 10/10

[@davidcormier6954]

Thanks again,always great to get the clarification on these widely disputed subjects. Good to have someone doing the homework.

[@timclancy871]

I really appreciate that you read a number of studies then give us a breakdown of the findings and tell us what the preponderance of evidence shows. This really helps to clarify the picture. Thanks Dr Gill!

[@lponced2002]

Love your videos! Being in the healthcare space and with a recent trend in lifestyle interventions, these are the types of topics and summaries that we need! I’d like to see a topic around different oils and their impact on weight gain, and with an interest more in the volume of fried foods that one eats.

[@Fomites]

Great work in this video - congratulations :-) Thanks for all the hard and meticulous work along with references. I wish more videos for the general population on health topics took your approach.

[@JosePerez-pn3ke]

Thanks for your focused view on this hot topic! Every video your team puts out makes my family and me healthier and more science-driven consumers.

[@showardnutrition]

I'm also a nutrition student 3rd year, motivated to study by all of the misinformation out there. I have just discovered your channel, the algorithms are working their magic for sure. I'm so grateful for all of your work. Navigating through the literature is tough going for some, but you present it in such a way that is so easy to understand. I appreciate your graphics too. Honestly, thank you so much. You have gained yet another new subscriber.

[@faikerdogan2802]

Then u better know to be hyper skeptical of any video with a title like (the evidence no one shows). It's in a way saying i know better then everyone else. Strategies consperisy people use.

[@TudorIrimescu]

If you start with the disproving "misinformation" card you will be left surprised at the fact that nutritional science does not work in absolutes which you seem to try to find. Keep humble and realize mechanisms have multiple ways of functioning and context matters, otherwise you'll fall under nutritional dogmas which this industry needs less, not more of.

[@grainiac7824]

@@TudorIrimescu I was about to say the same thing. Why not strive to provide accurate information supported with solid peer-reviewed research rather than using an over-politicized term like that about others' inflammation..

[@grainiac7824]

@@faikerdogan2802 To be fair, it's not "what I know" that is being promoted, it's peer-reviewed data as well as multiple studies on each oil and acknowledging possible weaknesses like weight loss affecting the changes in inflammatory levels etc. I think he did a good job overall.

[@micpoc4597]

@@faikerdogan2802 It is not "a way saying i know better" AT ALL.

[@alexanderdeiker9634]

You are literally the best science channel I have found so far on YT! Keep the insane work going!!!

[@jaeryu97]

Your videos are getting better and better Gil. Well-structured and easy to understand. Thank you for making the content.

[@Sarsaparillamann]

Really well done video. Appreciate all your work answering these nutrition questions!

[@bibifitness1968]

Wow Gil, the amount of reading and researching you have done on this topic is very impressive. I wonder how long it took you to put this video together, thanks very much for your hard work!

[@debravictoria7452]

He said two years in a comment reply.

[@Mimulus2717]

Would love a video on the effect on weight gain or loss due to the high energy density of fats (from oils especially) and how it can impact cardiovascular disease (blood pressure, ApoB, etc). Thank you for your cogent and easy to follow lectures.

[@rosevanderreijden3216]

That is the crux of the problem. People don't like to face the reality of calories in/calories out. It's too frustrating and difficult for many people who struggle with weight issues.

[@someguy2135]

Years ago, one of my doctors suggested that I should gain some weight. I heard that olive oil was benficial to health, so I started to pour it on my food like syrup on pancakes. I did gain more weight than ever before, but all around my belly. I knew that wasn't healthy, so I stopped doing that and lost the belly.

[@august4633]

@@someguy2135 You probably already know this, but what areas you gain weight mainly comes down to genetics (assuming your hormone levels are healthy) and not the types of food you eat.

[@debravictoria7452]

@@someguy2135 Did you have your cortisol levels tested when you had the belly fat? Wondering if it went up.

[@contact2001]

@@someguy2135instead you should have started eating more protein rich foods like legumes, nuts and seeds and startet resistance and weight training. Muscles would grow you get the extra weight and maybe even looked better. Just saying

[@jamato8461]

Thank you so much for videos. The work of deciphering all of scientific studies out there on general health topics is very important. The media likes to only interested in feeding people junk science for ratings. Kudos to you for helping people navigate through this!

[@loriegosnell9355]

As usual you wrapped all that information into something making sense with reliable sources. Thanks 😊

[@PClanner]

Gil, many thanks on your research as I have been spooked by the internet "doctors" that claim that this is a area of concern. Please keep on giving this information as it is important to living.

[@joecheffo5942]

There seems to be a strong connection between vegetable oils and macular degeneration. That “spooks” me a lot.

[@debravictoria7452]

@@joecheffo5942 Wow. I wonder if it might be a trigger for certain genes?

[@rokzane]

​@@joecheffo5942 Correlation does not equal causation. Macular degeneration is often genetic and runs in families. Excessive exposure to UV rays can also cause it. Since most people consume seed oils most of their life, and some people develop macular degeneration and some don't, no one can definitely say that seed oils contribute to development. The only thing I've seen is a grant proposal arguing for a study in this area. I haven't seen any published conclusions, just a lot of speculations.

[@bellenesatan]

​@@joecheffo5942and an even stronger connection between Nicolas Cage movies and drownings. Spooky!

[@everstormz]

I've definitely been following the anti-seed oil bandwagon. Thanks for putting this episode together and giving me perspective.

[@alquinn8576]

agreed, this was very well organized, and it's good he mentioned the longer-term studies, since some arguments against seed oils have suggested 8-12 week trials are not sufficient for any effects to measurably manifest. i avoid seed oils as a precautionary method (and also because they have no flavor) because omega-6 was not consumed in high concentrations in our ancestral environments--though the end of the video argues it's plausible our bodies nevertheless have a mechanism to maintain homeostatis with respect to the concentrations of resulting metabolites.

[@AlwaysSeekingTruth13]

Great job, Dr. Carvalho! I'd be interested in learning about the effects of these oils (and other oils/foods in general) on ApoB levels.

[@ginaferraro1967]

I am a university college teacher in Australia and consistently seek out current evidence in a range of health areas to ensure I am relaying the best information I can to students. I found this thoroughly educational and loved how you managed to pre-empt my questions and have them all answered by the end. This definitely threw a few of MY beliefs out the window. Thank you for putting in all this work. I completely understand and appreciate the efforts you went through in order to make this video. You have a new subscriber. 🙂 Update: This is not to say I have thrown all of my own beliefs and knowledge out the window. I just appreciate opposing views and the literature that might back them. There is also evidence out there supporting the risks of vegetable oils, showing we can find papers that support both narratives. I personally will be steering clear of vegetable oils wherever possible.

[@richardteague5563]

Is damage to mitochondria related only to inflamation -- or -- does rape seed relate to mitichondrial damage through means other than inflamation?

[@StillTrustNo1]

You can also find data supporting smoking, that's why we have the heirarchy of evidence. The man made his video from the top of the heirarchy, to reply to that with "well I can cherry pick and reach a different conclusion for myself" ... can you seriously defend that behavior logically?

[@supertuscans9512]

Not if it’s virgin, cold pressed.

[@wallerwolf6930]

While I can understand your "views" (opinion), scientific knowledge should not be based on opinions ;-))

[@WonderBoy0403]

​@@StillTrustNo1Thank you. People are so lost and straight gullible. Dying for someone to think for them

[@ash9259]

Brilliant video! Learnt everything i needed to. The only reason i do not consume seed oils is because i find it affects my cardiovascular performance negatively and i gain unnecessary weight as well, i become more suscepitable to insulin resistance which does me no good in terms of training. Knowing that the bulk of studies point to seed oils not having an inflammatory effect on the body in human trials is very important information so thank you for doing such a noble service in pointing that out against the controversies.

[@SlurpKing100]

Wow this must have taken alot of time, well done. I'm kind of dissapointed that so few studies specified whether the oil was refined or not, and that there wasnt many comparing seeds to refined seed oils. I think thats where the interesting part lies. I'm worried that most of the positive molecules you would find in these seeds are lost during the refining process, and removing them from their protective shell exposes them to oxidation. Really hope you are going to make all those other videos you mentioned. Oxidation, cancer, and heart disease (that one is definitely contentious). If you're not already knee deep in the research, Martin Grootveldt has some really interesting research on frying with PUFA rich oils.

[@brianzielke1510]

Great job Doctor. You are worth your weight in gold! A godsend for us fact seekers. Keep up the great work. Brian Z.

[@kamilradecki5590]

You're awesome and I really appreciate the work that you do. This is super beneficial in helping me figure out what is best for my family's diet. Thank you!!

[@denofpigs2575]

I appreciate the work that you put out specifically because you present the information in a non judgemental and open minded way. Not many people do that. Too many people treat the spread of misinformation as a product of stupidity but i dont think thats the case most of the time. Seems to me it's a product of mistrust and overcorrection from disillusionment. Thank you very much for the work you do.

[@rokzane]

More likely, it's because people want to believe their own narratives and resist anything that disproves that. It's human nature, really, and a defense mechanism to resist taking responsibility for our own poor choices.

[@wildebeestwright]

Thank you for addressing seed oils and inflammation. It would be great if you’d continue in this vein. I’m particularly interested in the effects of seed oils regarding cholesterol and heart disease, and also their potential effects upon the development of dementia and Alzheimer’s.

[@quisge]

100%. Came here to say this. Thank you.

[@Trazynn]

There's very little research on this. Though some experts speculate that omega 6 fatty acids interact with cholesterol and oxidize it, which is bad.

[@Nobody-Nowhere]

@@Trazynn There is actually massive amounts of rechearch on this, and it all points to the direction that replacing saturated fats with omega 6 LA is always beneficial considering cardiovascular diseases.

[@debravictoria7452]

@@Trazynn Isn't there a connection between oxidation and inflammation?

[@signs80]

@@Nobody-Nowhere I believe that the Sat fats -> PUFA substitution only tends to have a statistically significant positive effect on blood markers for people consuming >10% of their daily calories from saturated fats. If you are already eating them in moderation then replacing them with PUFA sources won't help or hurt you

[@emeraldsky3325]

Great video! As usual. 😊 Please continue to do videos on seed oils and other oils for health effects other than inflammation. It’s one of the few foods almost all of us consume. I am learning a lot about nutrition and I have to say oils are one of the few areas where I am totally confused whether it is good for me or not.

[@terry2346]

Wow! What a comprehensive coverage of the oils! Kudos and very interesting results. Best coverage I have seen on the internet!

[@quinterodpablo]

Thank you very much for the content. Could you please consider uploading a similar video on animal fats like lard, butter, etc.? What happens when someone cooks with these fats and keeps their corresponding calorie intake below the maximum advised level (10%), especially concerning inflammation or other long-term health issues? I have found papers on negative effects of those fats but they show high levels of consumption and, of course, there are other variables that make it confusing for someone without expertise. I would immensely appreciate your insights. Best wishes for you and the rest of the team.

[@chiclett]

You would need a study on long term consumption, which would be hard to do.

[@Ida-Adriana]

@@Marr033No they do not.

[@simpsonak5]

Excellent video. Straight to the point, no BS, and with the right amount of detail to not leave any hanging question. Can you tackle next th relationship between seed oils and the brain / dementia? Thanks

[@mariapereda9006]

Finally a doctor who has really made a profoundly rational study of the subject! I thank and congratulate you for the research, and especially, conclusions.

[@JulienRoigHerr]

Just decided to comment and like every single one of your videos that I watch. The effort you put into them is very much appreciated.

[@Jan-Jan-Jan]

I would be curious for a video on high protein diets on (long term) health. Thanks, I learned so much again.

[@elduderino1329]

I've been waiting for this video for so long. Thank you for your hard work and your willingness to dig deep into the subject without bias.

[@Drewsarchus]

i recently found your channel (within the last few days) and thank the lord i did. there’s so much hype and misinformation on the internet in the diet and nutrition space. unfortunately most of my family is highly susceptible to bad information online and constantly falls for the newest fad or extreme diet. so i’m constantly hearing this stuff. i try to remain metered and reasonable in my approach to these things, but often lack the scientific background to rigorously look into any of this myself, and i’ll be fighting talking points derived from an aggressive influencer who has manipulated the information in a convincing and emotional way, and it’s a losing battle. your videos are helping me a lot!

[@dan-qe1tb]

He's one of the few sane ones on here who: 1. is a real practicing MD, 2 doesn't specialize in opinion pieces over science, 3. doesn't pick fights with people he doesn't agree with. 4. provides references for his work, 5. talks about clinical trials

[@patrickgurley2480]

Pharmacist with a masters in clinical nutrition here, you put out absolutely amazing content!

[@NutritionMadeSimple]

thank you sir!

[@paulwolstencroft4820]

The best video I have seen relative to overall clarity, unbiased openly comprehensive research supported believability. Thank you kindly.

[@sammychem5920]

Thank you so much for reviewing all these studies! As a researcher, I would like to point out that the sample sizes in most of these studies were very small to make generalized recommendations to the entire population.

[@rokzane]

They may have been small, but they were also consistently repeated in different demographic groups. That's a more significant point that lends validity to the conclusion that seed oils are at worst benign to the majority of the population but can also be protective. It's only under extreme conditions, like repeated high heat frying which causes damage to the oils that we really have to be careful with use. So if you want some fried food, make it at home!

[@aaaaaaaaaaa5820]

I love how in-depth and as non-bias(as possible) you go. Earned my sub in one video

[@musicmonsterman8395]

Absolutely love all of your videos. I have been learning SO much. Keep it up!!

[@mikemcnally1454]

Well done, and thank you for tackling this topic. Another sensational video, Gil.

[@MasonOfLife]

I tell people that breathing is good for you, even essential for good health, but since I’m saying something positive about anything at all, they assume I’m being paid by big air

[@batira]

But then too much air is bad for you (hyperventillation), according to eg. the Buteyko system.

[@MisterHowzat]

Maybe that's just hot air 😂

[@johndunn3492]

How dare you air your grievances in this way. I’m getting inflamed.

[@michaelmione]

This is terrific content. Thank you for taking the time to put this together. I've been driving my family mad with seed oils before finding this.

[@grainiac7824]

Thanks so much!!! I feel like I"m on my own to try to figure out why my pre-diabetic numbers are not responding to the typical regimen of low carb despite returning to normal BMI and exercising etc. So I"m looking at inflammation and there is so much conflicting info. Your time and attention to peer-reviewed evidence and explanation is GREATLY appreciated. One you tube video called all seed oils "evil".

[@silvialittlewolf]

Thank you for your research and for clearing this up. It annoys me no end that people grab just one finding or even just part of a finding and push it out as "the only truth" just because it suits their own agenda. 🙄

[@themotivator2587]

Thank you so much for this video. I know my biggest interest regarding oils and fats revolves around how they affect cardiovascular health. The current Cordioprev study has been coming out with some promising results. I've been very cautious about using oils in the past and have used olive and sesame oil only sparingly. It would be nice to have evidence that plant oils generally can be used without cardiovascular risk. Though coconut oil might not make the cut on this one. I would love to find out otherwise because I love Thai food and curries made with coconut milk. They just don't taste the same with substitutes.

[@douglasharrington687]

Exceptional summary on these trials-one caveat, one could also hypothesize that the inflammatory markers used are not specific enough to the target organ which is usually the endothelium to identify a response one way or the other. For instance, hsCRP comes predominantly from the liver in response to cytokines secreted by the target process so is an indirect measure (but an acute phase reactant). Inflammatory markers like CTACK, MCP, HGF, Eotaxin, FAS, FAS-Ligand, and IL-16 might be more appropriate as being more direct and sensitive. Still a great overview-thanks.

[@krisjustin3884]

Yes, he’s a great researcher and presenter, but you have also given excellent evidence as to why I am more interested in feedback from practicing clinical doctors and patients. Research tends to limit material to predetermined outcomes as there is too much money at stake.

[@henrikmadsen2176]

Very interesting point! Great!

[@lseh4720]

I’ve been worried about my taking Black Seed Currant Oil because of possible inflammation. But it’s made a HUGE difference in my menopause symptoms. I don’t even have to take e-trace anymore. My OB had even suggested surgery. It blows my mind that women have surgery annually to deal with these issues, but without the BSCOil’s, I was in pain all the time. I feel better now about my taking BSCO. Thanks Dr. Gil!

[@zhilahaghbin4766]

Thanks so much, I have discovered you recently, what a pleasure to listen to you, you are a great communicator and professor, more importantly you know how to read and analyze research papers. you really give the "bird's eye view" of the matter, so talented you are, glad to have discovered your channel and I am getting great education.

[@twkbtw]

What an underrated channel. Gil is solely evidence that ordinary people cannot digest good quality content. :)

[@peterfaber7124]

Question: You said that people replaced the oils they normally consume with the oils the researchers supply. Considering the whole world uses seed oils in their food,... doesn't it make sense that you don't see many differences between before and after? They're replacing seed oils with other seed oils. 🤔 As to the studies that really increase linoleic acid,... they are replacing something with linoleic acid, I assume. Are they replacing carbs with fat?

[@jmarksyers8229]

I like your nutrition videos and how far you go to stick to the facts/research, while avoiding ad hominem attacks, etc. I have to ask if you could, or have perhaps already done any video about the potential benefits of vitamin B1, benfotiamine and alpha-lipoic acid for diabetics. I have seen numerous videos on YT about the benefits of B1 for protecting damage to kidneys and nerves, especially for diabetics, and for possibly remediating tinnitus. Especially videos by the Sugar MDs channel guy, and others. I was thinking of a particular seed/seed oil that is apparently pretty high in B1: sesame seed/ ss oil and tahina/tahina. I've also seen at least one video of the dangers of B1 supplementation for diabetics with Kidney damage. Since this also seems to, at least peripherally, intersect with the subject of this excellent video - that you made, I was wondering if you might consider looking into all of this and consider making a video summing up your conclusions on any research and/or significant anecdotal reporting about the related risks/benefits for B1/benfotiamine and alpha-lipoic acid supplementation. Also, perhaps some discussion about how much of those benefits could be obtained including some tahina, toasted sesame seeds and/or sesame oil in one's diet?

[@SunFellow941]

We need more of these types of videos! Educational and focusing on issues that are "hot button" topics on the interwebs!

[@Futzylogic]

Great explanatory video, as always. The effect of repeatedly deep-frying snack-foods in oil, up to 20 times, would help evaluate the (expectedly, deleterious) effect of street food, like in India, where the same oil is used through several cycles of cooking until it turns a deep, dark colour. Presume there's a lot of carbon precipitated out.

[@jeffh2125]

I'd never eat anything deep fried from a restaurant or food vendor. Oil changes are expensive.

[@michaelharned8741]

Burned fat is the worst fat you can eat

[@supercal333]

Instead of inflammatory markers, I'd like to see studies that test effects of these oils on cardio-vascular health.

[@NutritionMadeSimple]

hi, we covered that here: kzbin.info/www/bejne/lYfadY2Ml8ulgdE

[@dvdmon]

Thanks so much for this excellent breakdown on the literature re seed oils and inflammation. Now that you've cleared that up, I wonder if there are other markers that you could analyze that could contribute to chronic disease - blood lipids most notably, but also maybe BP, BS, IGF1, etc.? I believe you've discussed outcome data in regards to larger dietary patterns, and I get that singling out a specific food is usually not the way to go, but are there meta analyses that try to resolve larger issues of health benefits risk when it comes to oil in general or different types of oil in particular? I know some of the Mediterranean diet studies indicate that olive and canola can decrease some risk factors... Personally I avoid all oils at home, but when I do eat out, which isn't very often (maybe once every couple of weeks?), I will sometimes opt for a dish which I'm fairly certain has some oil in it, simply because most do (that are not just pieces of meat that is, which I don't consume). I do this mostly because oil is so caloric that consuming it daily would add a lot of calories and make it harder for me to maintain my desired weight...

[@se56]

This is the best nutrition channel I have found yet. Good job!

[@MsSturbuck]

Could you make a video on inflammation in general? How much influence do we really have and how can people with inflammatory conditions lower their inflammation as effectivly as possible (in addition to drugs) ? There is so much confusion- bone broth /greens/ fish oil etc....

[@VirgoVibe]

I was just about to comment this.

[@jicalzad]

Yes, excellent comment.

[@JamieR]

Second this. There definitely 'seems' to be a lot of evidence for yoga, meditation etc having an inflammatory lowering effect. Though it would be great to get a properly vetted breakdown of what's actually effective and what's not. If you've taught us anything; it can be quite complex to get the real truth without the proper understand.

[@JamieR]

@@Engrave.Danger Did you use a lot of cold pressed seed oils prior to cutting it?

[@RobertWadlow292]

There isn't really "so much confusion" regarding inflammation. There's a ton of studies showing different nutraceuticals and food components can lower inflammation

[@SlightysBack]

The amount of meticulous research you put into these videos is really incredible! As far as I know the most valuable channel on nutrition at the moment. Also love that you always take time to explain scientific processes, and how they should be interpreted. Your work is much appreciated! :-)

[@linusb1938]

I read malicious instead of meticious and i was about tho write a trantrum hahahaha

[@fionaewen6231]

Im not convinced tests for inflammation are to be trusted. I was told by a doctor l had no inflammation markers,but my knees were burning with pain. Somethings amiss .

[@GermanTaffer]

I agree. I invested in Biotech companies and had to read a lot of papers very fast and to evaluate it. But Gil really does a big effort to present the scientific data from different perspectives. So before anybody start to criticize Gil, he/she should ask him/herself, if he/she did the 1/10 of the work done here. I hadn't, so I a happy with the results. I wish that there would be so many studies out there about infectious transmission. I fear, in the next pandemia we don't know what to do exactly and what not like in the past 3 years.

[@peterodonnell4404]

I have just encountered your channel. It is wonderful to see that some people still look at the science. Bravo!

[@shinola228]

Great video. Thanks for taking the time to make it. Definitely answers a lot of questions.

[@elsagrace3893]

This is crazy. I’ve been avoiding soybean and canola oils for several years now. I do t even know where I heard the myth that they are inflammatory. Really frustrating but it has helped me to stop buying processed junk which is full of soybean and canola oil 🙂

[@bigdogblackie]

Just cutting down the processed food is a good step in the right direction for overall health, since there's way more nonfood, unsafe garbage there, even if seed oil for harmless. Skittles are illegal in some countries due to the 2 yellow food colorings.

[@yolkthosenuts]

Joe Rogan was a big perpetuator

[@jbarber1016]

Well they aren’t going to be as good in junk food and they are probally GMO heavy pesticide if they are not non GMO or organic. Especially corn and soy in the US.

[@orthotron]

​@@jbarber1016"GMO" is another topic like seed oils. GMOs are not by default harmful.

[@adamcorfman573]

Understandable. I hate how much I understand from having an associates degree in Exercise Science and Nutrition. This is essential! People shouldn't have to get a degree's worth of understanding to accurately sift through and avoid the bullshit that companies sell in the grocery store! I see many arguments that try to link or show a correlation with the Obesity Epidemic with the rise in the use of vegetable and seed oils. I immediately counter that argument with the fact of the rise in snack foods and the culture around moving less and eating more. Just so happens many snack foods are made with seed oils. It's cheap for companies to mass produce these "foods" (I emphasis the quotes around "food" since they're energy dense and lack many vitamins and minerals and other nutrients) using oils, instead of animal fats, so yeah, of course there's a correlation with seed oil usage and increasing obesity. It's not the oils themselves though.

[@mariaespiritu9512]

This makes me happy. My mom’s cardiologist placed her on an oil free plant based diet and it’s increased blood flow to her leg and it’s given her both her and I very great benefits. But our family loves cruising and it would be difficult to eat oil free on a cruise. They can accommodate plant based, but not oil free plant based. So, your review has given me a great sense of peace. Also, thank you for providing your method of research. I’ll apply it myself when researching topics that I’m interested in. Thank you!

[@jussilahteenmaki3475]

Probably your mom benefits the oil free period currently to gain overall health balance, but a period with oils if good oils, does not probably make any harm. Not to forget the daily exercise!

[@dvdmon]

Not to burst your bubble, but inflammation is just one aspect of heart health. Something could increase plaque but not be imflammatory. Also, most of these studies are done on people who don't have diagnosed disease, so it's a bit less clear for those who do. I am not suggesting consuming oil is unhealthy, just that we don't have the data to really compare no oil diets with diets that do have oil (specifically healthier ones with predminantly polyunsaturated/monounsaturated fats vs. saturated). I personally follow a diet that is plant based and I don't consume oil in the house, but occasionally do when I eat out. I also have heart disease. So I don't think consuming oil at least occasionally is going to be a significant issue, but I also know that vacations and cruises in particular are rife with temptations and excuses, so I'd be careful. Just because you enjoy going on these doesn't mean you can't do them without oil, or without a minimal amount of oil if that's what has been prescribed. I've heard that cruises can be incredibly accommodating to almost any diet out there, and I've heard of people who don't eat oil asking for this on their cruise and being accommodated by lots of steamed veggies, cooked grains, beans, etc. As you probably know, there's no NEED to cook with oil, so a cruise chef should be able to do it just as easily as you (or your mom). I'm not saying this is necessary, and ultimately it's your or your mom's choice as to what to eat on a cruise, of course, but just know that it is possible and I would really ask them about this first just because you may be surprised at how accommodating they can be. Good luck!

[@mariaespiritu9512]

@@dvdmon agree with you 100%. At home I cook with zero oil, I don’t even buy it. After her stroke, my mom developed ulcers around her foot, while in inpatient rehab, because they didn’t mover her leg enough. When she was discharged to home, I was told by wound care that they would never heal, because of low blood flow to her legs. I had purchased Caldwell Esselstyn’s book, reversing and arresting head disease and after a few months, they completely closed and healed. According to wound care, who is also part of the vascular team, she has an increase in blood flow to the leg. They were amazed because she had no surgery. Also, a year post stroke, she keeps getting better. She’s talking more and moving more, where she was completely paralyzed before. She had atherosclerosis in some arteries in the brain, maybe they’re opening up a little more too. I’ll continue to play it safe. We won’t be cruising till next year anyways and when we do, I’ll ask for oil free, maybe they can accommodate.

[@mariaespiritu9512]

@@dvdmon also it’s so easy to gain weight with oil, just a couple of spoons is 240 Calories. I’m not Interested in using it, at all.

[@mariaespiritu9512]

@@dvdmon and yes cruise lines are very accommodating. I might bring Esselstyn’s and McDoougall’s cooking books and hand it to the chef. There are always people requesting a vegan diet, to the hostess/host. The chef could use the book for them too.

[@glen7695]

This guy presents the most thorough and scientifically based nutrition advice I've seen. Thanks Dr. Carvalho!

[@greenmedic88]

Really appreciate the time taken to review the studies that respond to so many of the questions over diet and nutrition in current circulation. So what is going on specifically with highly processed foods using refined ingredients (refined vegetable oils, refined grain flours, refined sugars) that appears to be correlated with declining health and markers, almost in direct proportion with increased consumption levels over the decades? If it's not the refined carbs (sugar, grain flour), and it's not the refined oils, whether used for cooking or consumed directly, what is the cause? Is it a simple issue of consumption levels in terms of overall caloric intake and subsequent weight gain over time, as it is easier to over consume processed foods made with refined ingredients?

[@tinyjungle_]

32 minutes and I was craving more. I could have watched this for hours. Love how you deliver information and teach. I've learned a lot about nutrition and nutrition science since going plant-based almost 10 years ago but the level of understanding I get from your videos is second to none. You are invaluable my friend. Thank you for what you do.

[@albrackets8446]

FUTURE REQUEST: Please review the research on the effects of glyphosate ( RoundUp ) on our food supply and the prevalence of trace elements found in food products purchased.

[@NoirHammer]

Thank you Dr. This is what I was most concerned with when it comes to seed oils. Now, all I have to do is keep track of my Omega 6:3 ratio and enjoy life.

[@13AS89]

I'm wondering how these oils are being consumed.. with high heat or just put onto foods? Also what is their sugar and refined carb intake during those trails? I think nutrition is so complex and there are so many factors to look at

[@bhargavimurali2621]

Hello Dr. Gill, Congratualtions on another brilliant video! Is it possible to look at coconut milk, dessicated coconut, and tender coconut impact on health? I know you have explained the spike in Apob lipids from coconut oil. However, culturally in India, particularly the Southern states ex. Kerala has one of the highest consumption of coconut and its subsidiaries yet they have the highest life expectancy in the entire country compared those states that don't grow or eat coconut. I am simply unable to understand how? If you could explore this aspect it would be great. Thank you once again. 😊 🙏

[@TheBoydTV]

Genetics and evolution probably explain a lot

[@lenguyenngoc479]

Life expectancy is around 75 in kerala, it's just average We don't care about 75s we need 90s even 100 duh

[@carinaekstrom1]

There are many factors that influence life expectancy. Affluence, social status and health care being some of the most important. Also, there are time lags to consider. How long have people been eating this way, or that way, before they die. And for how long are they sick before they die? Health expectancy can be more important than life expectancy.

[@chrissafe3342]

World life expectancy rates based on diet are all bullshit. I'll bet most of India has not got access to vaccines and a+e healthcare

[@aureliaglenn2220]

Do the people of Kerala tend to eat lots of coconut as coconut--in other words, lots of coconut "meat" (the pulp), and not just coconut oil? It's possible that the high fiber content of the coconut counteracts the effects of the saturated fat content of its oil when consumed together (whole).

[@stepheninczech]

I stopped eating anything that could possibly have seed oil in it for 2 weeks and the really bad bloody ankle eczema I've had my whole life actually started getting much much better. Then I slipped up and ate a big bowl of chips and cookies, etc. and it came back in a couple days. Trying again now, and my ankle is getting much better after a couple weeks.

[@NutritionMadeSimple]

great example. problem could be any number of components of junky foods, from preservatives to coloring to flavorings. good reason to go easy on junk food. may have nothing to do with seed oil per se

[@stepheninczech]

@@NutritionMadeSimple True, but I've tried cutting out junk food, wheat, dairy, and other things in the past for weeks at a time with no benefit. However, this time, I targeted any kind of oil product other than tallow I rendered myself. I continued to eat popsicles and pancakes I made myself etc. It's obviously not a perfect experiment, but I am astonished at the results. I suppose I should wait until it completely heals up, then introduce in seed oil into my cooking to see if it causes it to return. But honestly, after decades of dealing with this, I don't know that I'd want to bring it back for science.

[@NutritionMadeSimple]

@@stepheninczech yeah no need, oil not necessary in one's diet, totally fine to leave out as personal preference

[@lucasgroves137]

@@stepheninczech Lol, thanks for the brutal honesty. No doubt there's a limit for most of us as to what we'll do for science. 😂

[@stepheninczech]

@@lucasgroves137 I tried adding seed oils back into my diet for 2 weeks to see if my eczema would come back. No effect after 2 weeks. I then tried eating dashida soup base which gave some effect. Then I started eating doritos and my eczema got significantly worse. Still not sure exactly what is causing it.

[@walawala147]

At 24:16, you laugh at the risk the volunteers take when eating oil that is repeatedly heated, but just buy french fries at any fast food restaurant and you're getting the same stuff. Some go 2 weeks between oil changes.

[@taylorstoltrd]

The first canola oil study you reference was not looking at adding 1 Tbsp canola oil to the diet.... It was looking at 200 mg tocotrienols added to canola oil vs canola oil alone. They were seeing is the tocotrienols had an effect on inflammation, not canola oil itself.

[@NutritionMadeSimple]

that was the main goal of the study but you can see the effect of before vs after canola oil (I think it's table 2 or 3?). there was no increase in inflammatory markers

[@joeycmore]

Thank the gods for your science first approach. I'm fed up of hearing self-proclaimed gurus of health pontificate about subjects they make up or repeat from other gurus. Your presentation is refreshing. Thank you.

[@jacobdebernardi4385]

It's interesting that most of the trials investigated are on subjects who already have metabolic disfunction. I suppose this applies to healthy people too I can't see why not. I have cognitive dissonance about welcoming a product as industrial as seed oils into my life I will admit, though the evidence is obviously compelling. Thanks for your hard work

[@tofu-munchingCoalition.ofChaos]

You don't have to include it. I would even say there is better food you can eat instead (whole seeds). But if you have problems getting enough calories or it's in a (healthy) convenience product, you don't have to avoid it and it's a good option.

[@krisfarrugia6490]

Hey, could you please provide a numbered list of the sources in the description? That would be really helpful to find the sources that you are speaking about. Thanks Dr. Gil for the video.

[@louster35]

Wow that just cleared up a ton of confusion for me. Thank you so much Gil!

[@skeeterskater5884]

Surgeon here- well done video! Would like a same review of "oils" relative to impact on triglycerides, esp LDL. Dr Greger has vilified all oils for their high saturated fat content. A broad unbiased evaluation of this subject would be very welcomed

[@unicornguy9676]

To be fair Greger doesn't vilify oil. He just prefers that u consume the whole food equivalent to get more fiber, vitamins and minerals but he acknowledges that oils are far better than butter and trans fat containing margarine.

[@user-ed9dk5mw8w]

Fabulous episode. I wish there was some good information on cancer in relationship to seed oils . I have always heard that seed oils , especially when over cooked, are carcinogenic. In general, are there any other ways in which seed oils might be harmful?

[@davidkymdell452]

Anything "overcooked"....read burned.... can be carvinogenic

[@Lambda_Ovine]

thank you! omg! thank you very much for going over this and setting the scientific results straight into the conversation! I've been stressing these past months over trying to avoid anything that listed seed oils (like some roasted nuts and stuff). I'm glad I can basically not worry about it anymore

[@gro16]

You are second to none in the world of doctos and scientist on social media. And believe me i follow all of them. From George Church to David Sinclair to Mercola and Dave Asprey. You go in to the research you read you dissect and you bring us the unbiased findings. No prejudice one way or another. Thank you for that. It is always a pleasure to witness the best of the best.

[@Spyrit2011]

I am curious how many of these studies were done with heated oils, for up to at least 5 hours of heating, think in terms of a fryer that is on all day long, and even reused? Canola oil, blended oil, and peanut oil are the top oils used in restaurants. Restaurants will reuse oils until the oil is black.

[@Zren89]

If you had watched the entire video you would know that. I don't understand commenting on a video that you haven't fully watched.

[@chrisbowles5135]

Thanks Gil, although this makes me feel less perinoid about consuming something with seed oils given the conflicting information out there, I would prefer to eat my food in the most whole form, and it seems that most processed stuff contains seed oil, so its process by elimination. Kinda like chips may be unhealthy not necessarily due to seed oil but other stuff, vs vegetables

[@paigemccormick6519]

I appreciate this careful survey! It's changing my mind.

[@StevenBrener]

Absolutely incredible video - I didn't expect this going in. Great info, thank you so much!

[@FLpas4774]

Yea I mean it’s the best ever educational video

[@FLpas4774]

Absolutely!

[@dekkerlundquist5938]

Truly excellent summary, easy to understand and based on sensible and logical interpretation of the evidence. If only we had more channels and videos like this and less of the half-baked rubbish that infests our media these days! Please keep making this great content.

[@markaguilera493]

Are there other inflammation markers apart from crp? Could there still be inflammation with no elevated crp?.

[@MisterHowzat]

Hey Doc, I'm so glad to have found your channel. You look at the question at every possible angle and apply critical thinking. Your hard work is much appreciated 👍

[@judyg2889]

I truly appreciate all the work and dedication you use to share such great information.; solely to help other make a conscious decision on what to believe. Allowing us to make educated decisions for good health! You tell it how it is and merely share the facts ( evidence from All the many study sources) and break it down so the average person can understand it. Thank You ,Thank You !!!!!👍😊