Are We Actually Controlled by Mitochondria? Mindblowing New Discoveries

[@blacksmith67]

2 billion year old cell to a bacterium: “Louis, I think this is the beginning of a beautiful friendship.”

[@p0ln]

2 billion years, eventually through a leap of faith, some bacteria(he thinks) became a part of cellular life we don't witness until Cambrian explosion, or just before. it's a bit of a leap, turning bacteria into cellular life with multiple functions across a range of areas. Evolution certainly had nothing to do with it, so what did?

[@blackoak4978]

I was thinking of the fri me who crashes on your couch for a few day, then never moves out

[@raam1666]

Information theory makes evolution impossible

[@StevenWilliams-o7b]

peetah the horse is here

[@Rudol_Zeppili]

Even though paternal mitochondria in most cases are wiped out and their mitochondrial DNA tends to not be passed on, an overwhelming amount of the DNA which encodes the proteome of the mitochondria is actually Nuclear DNA, so both parents contribute significantly to mitochondria, the maternal side just sightly more so. The Mitochondrial DNA only encodes most of the Electron Transport Chain proteins and the mito-ribosomes and mito-tRNA, which couldn’t function without the Citric Acid Cycle proteins which synthesize the NADH and FADH2 required for the ETC to work. This isn’t to downplay the mtDNA as unimportant but rather to just stress the importance of the interconnectedness of the genomes both parents contribute.

[@Zeratul1005]

No way, one of my favourite science youtubers doing a video involving a cult classic video game like Parasite Eve!

[@villeind6159]

facts i was like....wait what lol

[@Garresh1]

That game had an absolutely amazing soundtrack.

[@rocketproductions1441]

One of us

[@OrbitalHUB]

Antone's let's play Parasite Eve

[@ramonpujals1133]

Hi Anton. Regarding mitocondria, there is a new field in psychiatry called metabolic psychiatry. Their main tenet is that mitocondria is the primary cause of mental disorders and those can be fixed if you fix your mitocondria. Proponents of this new approach are (among others) Dr Georgia Ede and Dr Christofer Palmer.

[@apextroll]

I watch a woman who stopped taking schizo-effective disorder medication for a keto diet.

[@mrburns366]

That sounds fascinating. That and the relationship between the gut microbiome and the digestive tract being like a second brain.

[@Voron_Aggrav]

It's certainly something that's quite a bit older than this being brought forward using newer techniques and understanding, I certainly will have to read up on this, as this lines up with my own experience and understanding of psychology which I've been using for over 20 years, where a healthy lifestyle and meditation can do a lot to understand your mental state and steer it, though I never would've thought it was actually influencing positively Mitochondria would be a key to possibly control you problems very interesting and maybe reading up on this might end up being the piece I was missing in my own work

[@soluteemoji]

I’ve done a small amount of mito research. It’s amazing how different they can be between individuals of the same species and how the Oxphos system is regulated at different stages of stress and energy use.

[@LuisAldamiz]

How different when we (humans) all come from mitochondrial Eve, who lived some 200,000 years ago near the Nile? You must be talking of another species altogether.

[@ToneyCrimson]

"And all this time you thought you were in control." -Mitochondria probably

[@Android-dg5ri]

PARASITE EVE O_o

[@LuisAldamiz]

You're also your mitochondria. Nuclear DNA may be a bit overrated.

[@scroopynooperz9051]

​@@LuisAldamizOr so the Mitochondria would have us believe!

[@Willy_Tepes]

Yes, stress can age you quickly. My hair was grey at 45 years old, but my hair color came back when I left my ex. Stress is probably behind many modern health issues.

[@trishayamada807]

I didnt have children with my ex, I got remarried and was told there was no way I would get pregnant without medical interventions. I had a baby a month before I was 40, another at 41, and a big surprise at 45 years old! All complication free pregnancies, natural childbirth and three totally amazing children. It’s amazing when you get rid of such extreme stress how much your body can heal, both physically and mentally. Plus for me I have three of my most favorite people on the planet now! ❤

[@bsherman8236]

My hair is gray since 19, insomnia sucks man 👻😵

[@raynersclips4223]

Yet historically speaking we’re healthier than we ever been. In 1900 a little more than a hundred years ago the average life span was 47 years. Now it’s close to 80

[@WhitefirePL]

@@raynersclips4223 We have better healthcare, better medicine and, as result, longer lifespan. But are we healthier?

[@romazone101]

@@raynersclips4223 The increase of life span is mainly attributed to reduction of infant mortality. Losing one in four children before the age of 5 really lowers the average. My favorite nonna was born in 1928 and as fit as a fiddle.

[@itzybitzyspyder]

As someone who has beaten Parasite Eve 1 & 2, I'm a bit of a mitochondrial expert.

[@giovanniprovost]

Dr. Klamp?!

[@michaelteegarden4116]

Are you something of a mitochondrial expert yourself? :D

[@Just_A_Simple_Time_Traveller]

Saw this comment before realizing that's a game and thought you'd beaten some rare disease or smth lol

[@beau9297]

You're awarded a degree if you beat the game? Do you do mitochondria research now? Sometimes I get extra sleepy...ahhh...doctor. You think I've got bum mito?

[@NecroRevenant]

read the video’s title and scrolled down to the comment section looking for the Parasite Eve reference. Even if part of me felt it was inevitable to find one, I’m glad to have done it nonetheless (and so up!).

[@joeblownogodontinvademypri2618]

Dr Lynn Margolis, "in her formative paper, "On the Origin of Mitosing Cells", appeared in 1967 after being rejected by about fifteen journals.[3] Still a junior faculty member at Boston University at the time, her theory that cell organelles such as mitochondria and chloroplasts were once independent bacteria was largely ignored for another decade, becoming widely accepted only after it was powerfully substantiated through genetic evidence."

[@kelleyrc5671]

Fun fact - She was Carl Sagan’s ex-wife

[@mechez774]

Hopefully the man who was smart enough to discover her work will win the Nobel

[@winterclimber7520]

sagan too? at some point its the medium not the message sister

[@grugnotice7746]

Aton is a man of taste. Parasite Eve is great. Love the gun upgrade system.

[@giovanniprovost]

I instantly thought of PE when I saw this thumbnail

[@C_In_Outlaw3817]

It’s a good song by BMTH too

[@PerfectHandProductions]

Came here to say it.

[@silicon1138]

Absolutely mind blowing. Thank you once again Anton. Your videos are one of the highlights of my day.

[@TheGiggleMasterP]

Wait so we're actually 10 Trillion Mitochondria in a trenchcoat??? Awesome. 🎉

[@Atok595]

Some people have the trans mitochondria.

[@jasonlow6943]

Wonderful.

[@Rudol_Zeppili]

Apparently like 100 trillion Mitochondria, but I can’t find a source for that so it could be less.

[@TheKrispyfort]

We are a colonial mecha suit

[@Receipt]

​@@TheKrispyfortI smoke weed, I'm an Orbital Frame 😎.

[@joeblownogodontinvademypri2618]

"Midi-chlorians in The Phantom Menace are part of a recurring theme throughout the movie, that of symbiotic relationships.[21] They were loosely based on mitochondria, organelles that provide energy for cells; like midi-chlorians, mitochondria are believed to have once been separate organisms that inhabited living cells and have since become part of them; even now, mitochondria act in some ways as independent lifeforms, with DNA all their own. Lucas established this relation with mitochondria, in particular the necessity of midi-chlorians for life to exist, as a metaphor for society; namely, he says all parts of society must get along in much the way the midi-chlorians and their symbiont do.[26]" [source Wookipedia]

[@nattydred2593]

I like the analogy of humans being ships, and biota being crew, together exploring the world. We even send out colony ships roughly once a day, though now a days, it gets flushed.

[@Puzzlesocks]

I don't really like that analogy because it seems to separate humans as something different from the world. If we were to use something close to that analogy, we are ships full of ships full of ships full of ships, and it's likely that we are on ships that are on ships that are on ships and so on in both directions.

[@Voron_Aggrav]

​@@Puzzlesocksit entirely depends on if the rest of the world hasn't gone the same way, if it's a commonality for everything on this planet to be structured like this, as currently seems to be the case it wouldn't separate us

[@Joe-sg9ll]

eww gooner

[@auriel8300]

*"Without the Mitochondria, life could not exist, and we would have no knowledge of the Force. They continually speak to us, telling us the will of the Force. When you learn to quiet your mind, you'll hear them speaking to you."* -- Qui-Gon Anton

[@skepticallypissed2074]

Perfectly placed movie quote.... nicely done

[@napoleonfeanor]

Mitochochlorians

[@TheKrispyfort]

Immediately thought this, too

[@Sucellusification]

Not far from reality

[@skepticallypissed2074]

@@auriel8300MMMM... look into this more , I must.

[@bravadita]

"If i destroy you, what business of it is yours?" - my mitochondria probably.

[@osmosisjones4912]

Why is all the selection on paternal side if all factor especially factors males are selected for are on the maternal side

[@Receipt]

"My body my choice"- Mitochondria

[@landonl958]

I was the only kid in Sophomore Biology to get perfect scores on the Mitochondria chapter. I was usually the kid who got no scores on all chapters. The teacher thought I cheated, but I told her video games carried me through, because they offered a far more interesting science lesson than she could ever muster. Huge thanks to my PS1 and my copy of Parasite Eve.

[@BasaBoi]

Damn. I literally experienced the same thing with my middle school biology teacher. I knew everything about the cytology organelle chapter. He was like, how? I told him a video game. I explained parasite eve. We had an awesome conversation and he was floored that a videogame went into such theoretical territory on the subject.

[@landonl958]

@@BasaBoi The extra reading material attached to the museum labyrinth and other similar things, like articles and books scattered throughout the game, was done similarly to how Assassin's Creed 2 would later map out Italy's historical references. I think SquareSoft did the best job giving the most accurate information on mitochondria in an order that is much easier to understand than any textbook. I'm so excited on this update from Anton, because I've been hard on mitochondria lately, but more on the relations with acids and alkaloids. It kind of led me onto a path about reading on alkaloids and the use of cancer medicines since 2013. I never did watch the live-action movie from Japan, nor did I read the book. But I did play the 2nd game, and The Third Birthday. There was still some good information in the 2nd game, but the original has recently been hitting my happy place, and ironically, I got obsessed again about two weeks back.

[@landonl958]

@@BasaBoi SquareEnix might still own the property. I wonder if bringing that one back as the original "Cinematic RPG" could bring them a much-needed massive win? I'll have to read the book soon.

[@bsherman8236]

Classic game, probably the first rpg/horror survival that i've seen, i still listen to the soundtrack

[@im415again]

My mitochondria are control freaks

[@Atok595]

I’m sorry for you.

[@historynerd6630]

mine are too

[@alb9]

My mitochondria are Jesus Christ

[@Bakarost]

​@@alb9yours have mental illnesses Dont worry mine too

[@pliktl]

Mine want to stay home and watch videos about itself

[@joeblownogodontinvademypri2618]

Also, note the similarity to Star Wars "midi-chlorians" without which "life could not exist, and we would have no knowledge of the Force. They continually speak to us, telling us the will of the Force. When you learn to quiet your mind, you'll hear them speaking to you."

[@Skiskiski]

2025 first mitochondria defense used successfully in the US court.

[@ossuseryoutube]

You obviously meant midi-chlorians.

[@derrickrr5516]

I’m late. You beat me to it. 😂

[@deal2live]

Lol

[@anearthian894]

"Mitochondria is the powerhouse" ❌ "Mitochondria is all there is"✅

[@youfoundityoufoundit6675]

Another wrong one : Planet Earth created life

[@Auroral_Anomaly]

@@youfoundityoufoundit6675No shit Sherlock.

[@wewillworld522]

Alien are into all of US

[@TailstheWizard]

"buuut it also involves a lot of murder, and a lot of violence, which basically made this, an amazing video game." lmao had me rolling, i too had a fun time playing this as a small child

[@seanbrazell7095]

My mitochondria are pissed that you blew their cover!

[@jabezcreed]

They would want to be found! They want to be fed!

[@seanbrazell7095]

@jabezcreed How DARE you put words Into their cell membranes! 🧫 ☝️😉

[@susanm9124]

Cool. Thank you! As always this is a great upload for us to enjoy.

[@ThisDique]

My God, hell must have frozen over. One of my favorite videogames has basically turned into a research paper. Videogames like this taught me how to read and take even more interest in the sciences. The possession and biological hacking of another being through mitochondria doesn't seem so far fetched of a concept now. They're a processor basically taking instructions and can even influence mental states.

[@whattmang]

Next month, they're going to discover Lavos is real

[@justyalicea2602]

DUDE! Long time viewer. When I saw the thumbnail, I was totally thinking about "Parasite Eve"! When you mentioned it I started cheering out loud. I also think it was one of the coolest plots of any video game. As a paleontologist that grew up really into biology and science, it really struck a chord w me. I later worked at the American Museum (Im a New Yorker) which was also in the game. Anton, I've always loved your work, but you are even cooler to me after this one. Cheers!

[@Captain.AmericaV1]

Picard: "Number one, plot heading to planet Mitochondrion, warp 6......... Engage!!"

[@jennifersaar1611]

Wow. Consciousness could be a mere byproduct of an organelle with an appetite.

[@TheJunky228]

I think it's some sort of emergent phonemonea once enough faculties are connected

[@rezadaneshi]

The ultimate evolution of mitochondria was consciousness. If the ultimate evolution of consciousness is connected collective consciousness, then finding out what physiological changes have to occur for us to evolve, perhaps will trigger its evolution with less trial and error. Mind blowing

[@Moxiumous]

what does this mean? collective conciseness is an interesting idea until you realize aliens are probably real and also have one. are we (aliens with consciousness included) all experiencing through consciousness? we probably do and will experience again after death in a new brain. obviously you wouldn’t remember anything before you were born and i’m not saying you’d be the same person “reborn” this isn’t reincarnation. you’d be someone else entirely with an entirely different life and brain. this repeats until there are no more capable brains in the universe to experience consciousness

[@rezadaneshi]

These are new mind blowing thoughts to me thanks to you and Anton. I can speculate only that a soul is not perpetual till it's capable of residing physically in a nourishing new Symbiosis and the only way is a depository of collective consciousness, like Aiwa in Avatar; and since I'm being ridiculous, Aiwa can be used as a hive mind. Most our studies find chemical (pheromone) like methods of communication in hive mind ants. So maybe our vocal nature is preventing us from developing additional chemical sensors into our physiology for more advance type of communications that can bring mitochondria to its reason for being from the getgo.

[@davedavidson8208]

​@@Moxiumousit's kind of wild how we are now at a point where what is essentially the philosophy behind "the force" in star wars, is now a serious discussion.

[@Trazel_Apeally]

@@davedavidson8208 The midichlorian is the powerhouse of the cell

[@johnwatters6922]

@@rezadaneshi "our vocal nature is preventing hive mind", try yelling FIRE in a crowded theatre

[@mundanestuff]

That's wild news. Especially the part about paternal mitochondria

[@kelleyrc5671]

This surprised me because I thought the paternal mitochondria were only in the sperm tail which was lost when entering the egg

[@roybatty2030]

It wasn’t me, it was my mitochondria

[@johnyharris]

I love Mitochondria, hence my avatar. It was Nick Lane who switched me onto the importance on these little beasts. It's obvious we haven't truly grasped how important they truly are. But it would not surprise me if they were responsible the the very nature of feeling and by extension consciousness.

[@DemonicAkumi]

I have a feeling my mitochondrias talk to each other with the interveins and not face to face. They have to be as antisocial/introverted as me to make me like this.

[@rezadaneshi]

So, mitochondria is a processor with an incalculable algorithm

[@edwardteach3080]

I come here just to hear that I’m wonderful. Thanks Anton

[@Atok595]

He said it to me first.

[@Rascal77s]

You both are!🍻

[@convolutedconcepts]

Parasite eve, there's a great game I haven't heard of in a long while.

[@fearlessjoebanzai]

Midochlorians! The "scientists" are spelling it incorrectly for some reason.

[@eldermorph6414]

We are a multicultural life form. We are a collaboration of multitudes of microscopic life forms working together symbiotically to form an individual human being. So to put it simply we are an intelligent microbial community learning and living as one.

[@john-draftanimal]

Mitochondria are important in the immune system, particularly in neutrophil cells. They are important in pyroptosis to fight cellular invasion, netosis to 'net' bacteria and parasites in the blood using expelled DNA, production of reactive Nitris oxides also for anti-bacterial effects and vasodialation. By the same methods however, they are also key players when inflammation and immune system goes heywire and very self destructive as in lupus kidney damage, lung damage etc.

[@SSGLGamesVlogs]

Thank you so much for not saying "Fun Fact" at the beginning of that.

[@SSGLGamesVlogs]

Hey!

[@banzaibill4290]

Far Far Away.. the Jedi call them Midiclorins..

[@gtd9536]

I've been fascinated by mitochondria ever since I first learned about them by reading biology books. So weird to me that people learn this stuff through video games, but whatever gets you educated. Reminds me of a book I read long ago which argued that tv (in this case games) were making people smarter.

[@JudgeAssessNotifyAcknowledge]

thank you for the video Anton. This subject has been on my mind lately so I was surprised to see a video on it in my feed tonight

[@Jacobk-g7r]

6:11 they share a relative to stabilize and share. The relative is the bridge kinda like how my arm is relative to me so i have potentials connected. Awesome stuff here.

[@antibrevity]

Thanks to the people doing the actual science as I've done none of that, but I have been suggesting that mitochondria were more than dumb generators for decades. Just as some scientists are now asking who serves who in regards to our microbiome, we can also ask whether plants serve our needs or vice-versa. These are all symbiotic relationships where our insecurities convince us that "we" exist as separate entities from other living things or are at least masters over them; somehow a desirable, and thus survival-enhancing, concept to the human mind. Sentience allows us to sustain comfortable beliefs that, in turn, make us better servants to the microbes and plants that partner with us. "We" is something that most humans are too insecure to imagine and that bias is itself an adaptation; ignorance is literally bliss.

[@byronedwards8157]

Ever since AP biology I realized the human ego is offended by our mitochondrial symbiosis or we would refer to our individual selves as “we.” That’s why we need our ego so we can think critically as individuals. But with too much ego we would forget we are part of the same living macroorganism, bound by a vast biome of microorganisms.

[@milanpintar]

omg that's how I learnt about mitacondria, through parasite eve, that was the best game!

[@jimcurtis9052]

Wonderful as always Anton. Thank you. ☺️😁

[@ikenosis8160]

Amazing video, Anton. Thank you. Liked and shared. Godspeed

[@rosskirkwood8411]

Anton you are mitochodridically energized.

[@Jacobk-g7r]

9:59 well what I’ve always imagined is that the mother is the incubator so the father brings differences so if the mom is the stable then she might hold certain foundations like an egg instead of the difference every time. It’s like sharing the current with potential. A house is a solid foundation to maintain stability and the fathers seed brings difference to help shape difference into a relative foundation. Sounds weird but just my thoughts. 11:48 yeah they might compete or cause mutations. It’s like fitting a puzzle piece into a slot, if the puzzles got an extra thing, it can cause interferences. Destabilization and relative collapse. It causes mutations or deformities probably or causes full collapse.

[@johnneat3381]

Whoa! That was incredible! Ty Anton, truly mindblowing stuff

[@p.alhadeffromrio]

1) Humility comes from surrendering to Mitochondria control 2) Mother's vindication comes from own Mitochondria being passed down regardless of offspring wishes.... Conclusuon: The Creator (aka God) has the best sense of humor 😅😅😅 👏👏👏 🙏

[@MoteofVolition]

This is fascinating! Thank you wonderful person!

[@darrenjurme7231]

You are awesome Anton. Thanks tremendously for this! ☀️

[@SJ-um2ym]

This was an amazing episode. Thank you for sharing your knowledge with us. You are an exceptional man and I hope someone hugs you every single day. You deserve it.

[@HermitCrone]

I love your videos, Anton! I love learning deeper about our mitochondria. I need a colorful mitochondria T-shirt, sweatshirt, or hoodie!

[@rb26sr]

That is truly fascinating! The rabbit hole of who we actually are goes even deeper!

[@konidk]

Parasite Eve 1 and 2 got me interested in this topic. Liked both games and wondered how much was true.

[@FredPilcher]

Fascinating stuff! Thanks Anton. 🙂

[@bdg77]

Good stuff! Thanks Anton! 🎉

[@endermanofficial]

you're in great physical shape ant. hard work pays off. good for you buddy.

[@derrickrr5516]

But Qui-Gon Jinn said they are called Midichlorians! 🧐

[@protoword10]

Excellent topic! Thank you for learning and information!

[@tcf70tyrannosapiensbonsai]

So we are under control of tiny legless ratmoles? 😊

[@Atok595]

🎉 ooooo

[@luish.delreal5229]

So that's what they mean when you feel something from inside telling you to do something

[@rafsandomierz5313]

Could it be that the brain of schizo person is actually just brain picking up mitochondria signals?

[@terrynewberg5732]

Thank you, this is fascinating material.

[@pierpaoloambrosi4740]

I KNEW IT! i knew there was something off about them... like, how can you just be the powerhouse of the cell? It was so obvious that was just a disguise

[@SapienSpace]

Fascinating! Thank you for sharing 👍

[@ericstromquist9458]

Extremely interesting video.

[@milanpintar]

this video is mind blowing, thanks Anton.

[@quantum7145]

good stuff, This has to do with the levels of Universal Conscious within us.

[@untouchable360x]

The force does really exist.

[@michaelteegarden4116]

Midiclorians for the win!

[@G0nxsf]

This is the way....!

[@paulschuckman6604]

May the Four Forces be with you.

[@SaraNeal-k9z]

As someone who’s got Mito dysfunction associated with autoimmune disease and neuromuscular dystrophy, as well as having 2 kids with the same (late onset for me) all of this is extremely interesting!

[@danielthemangrande]

Mitochondria - Look at me, look at me! I'm the Captain now.

[@stephenaltman5054]

Thanks again for the excellent post

[@iphonedoc]

Damn, this is great stuff. Thank you! Now I have to watch it again.

[@Kelly-m6l4h]

I love♥this topic! Co-existing and the microscopic world is like learning more about inner space which we know very little about but more than I realized has been learned.

[@tcluchito]

Wow mind blown, I have always being fascinated by mitochondria in biology class and I loved those games when I found them when I was younger.

[@ludlowworthington697]

I’m feeling less like an individual and more like a coral reef, a convenient place for a bunch of different life forms to hang out, find shelter, and eat.

[@tcreate.s]

Nice biology video. We owe our mothers endless love and gratitude 🙏

[@osmosisjones4912]

Emotions are simply energy releases energy flows

[@opiesmith9270]

My mitochondria liked this video. They were pleased.

[@wes_the_scifi_guy]

As long as your covering it I believe the content should be viewed

[@crossmission]

love hearing a reference to one of my all time favorite games, gotta replay it soon :)

[@internetmachine]

My mitochondria don't want none unless you got fun, hun.

[@zupurfeg89]

this is incredibly fascinating - and useful

[@phostings]

Holy crud! Parasite Eve was a gift by my mother for Christmas when the game first released! I learned about the Mitochondria through the mini-game in the museum! This one game got me so interested in Biology. And I still have the game in my collection.

[@larsgottlieb]

That smile at the end gets me every time

[@thomasferris3750]

Dmt attaches to the mitochondria, that particular action is already used by stoke ambulance units cause it greatly prevents post stroke symptoms as well as they are experimenting with long term treatment to reverse damage

[@igodreamer7096]

Parasite Eve is a Christmas game! 🎅 Great video, Anton man! ⭐⭐⭐⭐

[@khinmaungthein2624]

Amazing discovery, thank you so much Anton.

[@marcpigeon7796]

What a great vid, thanks Anton.🏍️🇨🇦

[@vaakdemandante8772]

Many Sci-Fi books, movies, games are not only inspired but actually informed about things that most people don't know to be true. The authors sometimes know more than the general public. Seems like this numt-thingy is a way for evolution to kick into higher gear when things start to look bad and a better adapted organism is required.

[@chrisose4585]

I’m pretty sure every microscopic life in me just argues with each other “I’m right” “No! I’m right!”

[@pjaworek6793]

Yes!!! I'm so deep in this rabbit hole right now, perfect timing!!!! Mitochodria are said to be the reason we have deep sleep, and REM.

[@billfrehe6620]

Very interesting subject matter, I hope to hear more soon.

[@jeremyschissler337]

thank you wonderful person !

[@mephistro]

I LOVED Parasite Eve on PS1 and I also own a 1st edition hardcover of the book! I have an obsession with mitochondria and really enjoyed your video! Thanks!

[@betanick14]

I did not expect to get a parasite Eve reference even though it was the first thing I thought of when I saw the thumbnail 😮 I didn't realize Anton was like. My apologies, I didn't know your game

[@EQ_EnchantX]

I played that game back in the day and it was so long ago it had the world trade centers as background buildings. Was a cool game, learned about Mitochondria and what it actual is. That is how Mitochondria Eve was able to cause people to burst into flames, it would make the Mitochondria overload and over heat. Was a very cool game, kinda creepy as a kid, but lot of fun.