Ask Me Anything About Bioinformatics #1

[@anmolaggarwal2651]

I have completed my bachelor's degree in Biotechnology and took admission in Mtech. Computational Biology/Bioinformatics. I was a bit worried about stepping out of my comfort zone since i'm not good when it comes to programming and softwares. I'm so glad i found your channel and this video boosted my interest in what i'm going to pursue. Also, you explain in such a simple and logical way that there's no room for any doubt. Thankyou so much for all your efforts in helping and motivating students like me in field of bioinformatics.

[@tejiyo]

Hey, I am also pursuing Bachelors in Biotechnology from DTU, I also plan to apply for Mtech in Bioinformatics. Can you please share where have you taken admission?

[@anmolaggarwal2651]

So i got admission in Mtech Computational Biology in IIIT Delhi through GAT B exam. And to be honest, the exam is relatively easy and a preparation of 6 months is more than enough to be among top 50. There is no need for letter of recommendation because the selection in IIIT Delhi is purely merit based followed by an interview.

[@DataProfessor]

Glad to hear of your success in MSc entry, great job!

[@khushpatelmd]

Bioinformatics vs Biostatistics: Which one do you recommend for someone focussed on Data Science? Thank you.

[@DataProfessor]

Since I'm into Bioinformatics, I'm a bit bias to say Bioinformatics particularly for me the application of machine learning to discover new drugs is an exciting and fascinating endeavor. In spite of this, Data science can really be applied to both.

[@TinaHuang1]

This is so so awesome!! Your answers are so clear and concise! 😍 I was doing some of what you described for my research project but felt like I didn't have the full context, which you explained!

[@DataProfessor]

You're so welcome! Thanks for your perspective 😊

[@DataProfessor]

🌟Don't forget to check out Episode #2 of the "Ask Me Anything" series: kzbin.info/www/bejne/eIS4aaqhgp55d6c 👉Watch this video next (How to learn data science in 2021) kzbin.info/www/bejne/pYOZaGOKrdybbpo Support this Channel 👇👇👇 🌟 Buy me a coffee www.buymeacoffee.com/dataprofessor 🌟 Download Kite for FREE www.kite.com/get-kite/? 👉 Subscribe to this KZbin channel kzbin.info 👉 Join the Newsletter of Data Professor newsletter.dataprofessor.org

[@sahadiyamandodan2228]

Hi sir i am from biology background and intrested to pursuing phd in bioinformatics or computational biology can you suggest me some ideas to find a research problem

[@yadavdeepak3765]

What are the future of bioinformetics

[@nawinmohamed6611]

what is the graphic view in bio informatics

[@DataProfessor]

It's molecular visualization and molecular modeling

[@ssil5889]

Your slides and videos are awesome! Not sure if you still look at these - but i am hoping you do. Is there a way to extract compounds/drugs from CHEMBL database that have 2 targets. For example, I can create a csv file for drugs that target aromatase and drugs that target estrogen receptors. How can i create a csv file for compounds that target BOTH aromatase and estrogen receptors.

[@nikitatomar1620]

What is the monetary scope of computational biology or bioinformatics ?

[@AntiParallali]

Hello! Thank you for this video, very helpful and insightful! I wanted to ask, what kind of interview questions do bioinformaticians get asked for job interviews? What can we do to practice for these?

[@DataProfessor]

Hi Lali, thanks for the question. Are you coming from a biology or computer background? The typical questions that I would ask during an interview for bioinformaticians would be general questions shown below (usually the applicant comes from a biology background, though occasionally some would have prior programming experience): - Do you have any research experience before? - Can you talk about the research project that you had taken part in? - How can your experience contribute to our research group's work in bioinformatics? - What project would you like to work on if hired?

[@AntiParallali]

@@DataProfessor I'm a biochemist turned into bioinformatician. 4th year PhD, so I definitely know more about biology than programming and I am hoping to learn more prepare myself for any coding question that will come my way. Thanks for your advice!

[@DataProfessor]

@@AntiParallali A pleasure and thanks for sharing! Oh and one more thing that I forgot to mention is that I would also ask the candidate to also share their GitHub profile which is a great way to assess prior projects that they have worked on.

[@abhaykshirsagar1166]

Can you suggest a project for someone who is new to bio informatics. I am a biology major and wanted to get started on bioinformatics. I do have a some knowledge in ML and Neural networks.

[@DataProfessor]

Hi Abhay, thanks for your question, there's actually a lot of potential projects that one can do in bioinformatics. Speaking of projects, I am in the process of finalizing a dataset that I plan to share publicly on the Kaggle platform, more information coming soon in the near future.

[@archardor3392]

@@DataProfessor That would be very interesting to see! Looking forward to it!

[@furens-aru]

KZbin algorithms brings me to your channel. And im glad it did.

[@DataProfessor]

Yay, glad its working, welcome to the channel!

[@kashchandler8028]

Pro tip : you can watch movies on Flixzone. I've been using it for watching a lot of movies lately.

[@ericjoel2425]

@Kash Chandler yea, I've been using Flixzone} for months myself =)

[@franciscobarahona1080]

Thank you, I'm newbie but I would you to ask who do you choose the specific compound ("Fungus compound") to evaluate its possibly utility in some cancer disease?

[@arnobsaha2361]

Can i do Masters in genetic Engineering /biochemistry /microbiology after completing my Ug in Bioinformatics Engineering

[@depressedindonesiangirl939]

Bioinformatics isn’t really a popular major in south asia, do u think if We study bioinformatics, we have to work abroad to find better job prospects? Is it needed?

[@DataProfessor]

Hi, at the very least I am quite sure that bioinformatics is quite prevalent in research universities (one can search for research papers by countries to see which universities are doing bioinformatics research). As for industries using bioinformatics, yes the big companies are mostly in the US, Europe, Japan, etc.

[@ziadshaaban3139]

Please I need a roadmap for bioinformatics with resources ??

[@tehreemkhan912]

Hey i was working in production of pectinase in my lab but due to covid we set back to home.. I was just screening bacillus subtitles in lab n now I have to continue my project with bioinformatics tools can u please suggest what best possible thing I can do for my project using bioinformatics tools..Plz rply asap

[@DataProfessor]

There's a lot of possibilities, depending on the hypothesis you have a wide range of bioinformatics and also cheminformatics tools that you can harness. One possibility is to make a web app (a bioinformatics tool) that others can make predictions with. An example tool we developed is at codes.bio/osfp and an accompanying paper is at jcheminf.biomedcentral.com/articles/10.1186/s13321-016-0185-8

[@koustavbanerjee4763]

I did my bachelor's in Microbiology and applying for msc I was wondering for my PhD if I should go for Bioinformatics and computational biology or Biochemistry and molecular biology or Biomolecular Science

[@huynhthichung9497]

Hi there!! I'm your new subscriber this month. I wanna learn bioinformatics in the university next year. May I ask with the bachelor of bioinformatics, where can we work after graduating from the university?

[@DataProfessor]

If in academia, you can further pursue a Masters or PhD in the life sciences as well as bioinformatics. In industry, you can work in biotech/pharma companies as well as data roles given that you also have also acquired coding and ML skills. The actual path may be quite flexible.

[@29anit]

Hello sir, is there any way to do RNAseq assembly from a big dataset (~300GB) for finding DEG quickly.. I am in hurry. Need help 🙏

[@DataProfessor]

Hi, RNAseq data is outside my domain of expertise, sorry.

[@codelucky]

As a Machine Learning Engineer, can I consume sufficient and usable knowledge on Bioinformatics via self-learning? If yes, how long can it take approx? I'm interested in DNA sequencing, have been reading about articles on CRISPR/Cas-9 since past few years and I wish to use it for building Healthtech projects.

[@aadimnepal6497]

Look into Dr. Eric Lander's Introductory Biology lectures at edX. That will be enough.

[@alinasayyed9593]

Do you also have lectures for basic bioinformatics tools and softwares learning ?

[@DataProfessor]

Yes, I have made several lecture and tutorial videos on Bioinformatics in this playlist: bit.ly/dataprofessor-bioinformatics

[@alinasayyed9593]

@@DataProfessor ok thanks!! 👍🏻

[@ammanhabib4770]

I recently took an Advanced analytics course in which we learned Bayesian networks to identify which genes influence cancer patients the most. Is the Bayesian network used in researching these types of research problems?

[@DataProfessor]

Yes, it has been used for network biology for deducing which genes contribute to observed phenotypic outcomes, which is useful for drug discovery and disease understanding.

[@KoliHarshad007]

How do I get into bioinformatics while I don't know biology but I know data science

[@DataProfessor]

Hi, that's a great question for a future video. In the meantime, please check out the playlist of videos that I made on bioinformatics some are step-by-step tutorial where I show you how to use Python to build a bioinformatics project from scratch, bit.ly/dataprofessor-bioinformatics Hope this helps 😊

[@shawn1868]

@@DataProfessor on the contrary, how do I get into bioinfo if coming from a pure wet bench molecular bio background? Thanks!

[@tejiyo]

@harshadkoli7 did you find the answer to your question? I am looking to do the same, but I dont know how

[@kapilkumar-jn4il]

Dear sir, please make video on machine learning energy gap representation

[@kenwong237]

Just wondering can bioinformatics be used to study the immune system?

[@DataProfessor]

Yes, it can definitely be. Immune system is comprised of biological macromolecules such as proteins and peptides and they can be quantitated and can be used by machine learning

[@mandarvaidya7947]

thanks for this I will be doing my masters in data science with bioinformatics specialization and ur channel is awesome

[@DataProfessor]

Hi Mandar, good luck in your masters study, glad you're finding the contents helpful 😊

[@mdtokitahmid2970]

The video was awesome. Would you please provide 1/2 papers using the concepts you discussed in drug discovery. My primary concern is about doing a publishable project in this sector, maybe not directly for market use. Thanks a lot!

[@shubhangisakarkar9532]

Thank u soo much for the directions. Surely I will follow the path.

[@DataProfessor]

A pleasure, and thanks for the question! 😊

[@anushkasrivastava2129]

Hey Shubhangi are you doing Bioinformatics in India?

[@anushkasrivastava2129]

If you are please guide me.. I want your help..

[@shubhangisakarkar9532]

@@anushkasrivastava2129 I am data scientist and want to explore this domain

[@anushkasrivastava2129]

Oh OK so I'm doing BSc Hons in Bioinformatics and it's my first year which means that my classes have just started, could you please guide me related to this field..

[@sushantadeb2469]

What should be the ideal configuration of workstation for microbial genome and metagenome analysis. Most importantly about core and ram.

[@DataProfessor]

Recent advancements in GPU computing has shifted the paradigm towards the use of GPU for such big data analysis. NVIDIA and its cuda cores will be instrumental in such big biology data analysis. I would recommend to look into GPU computing and find a GPU card that fits the budget.

[@saltanatkhalyk3397]

Thank you for such interesting video

[@DataProfessor]

My pleasure

[@oneman6472]

Should I learn data science firstly? Or I should learn bioinformatics immediately?

[@DataProfessor]

You can do both at the same time, apply data science to biology data. I have created a Bioinformatics from Scratch series in the following playlist (a 2 hour long lecture is also in there), bit.ly/dataprofessor-bioinformatics

[@DataProfessor]

In addition, I’ve also written about 10 beginner friendly articles on breaking into data science on Medium, bit.ly/chanin-medium

[@febinfawaz746]

Excellent classes! If I have only a few known (experimentally validated) compounds for a particular target, how do I build a machine learning model from it? Can similar compounds having interactions ( as seen in docking studies) with the target be used to increase the size of the data?

[@rakeshindukuri6095]

Thanks for lot of info. I was specifically looking for tools(If any existing) for big data management of these various types of data you explained in the video. It is so confusing handling lots of data.

[@DataProfessor]

For most of the life science data, a commonly used platform for handling data is platforms such as Galaxy, usegalaxy.org/ It might be worth a look, hope this helps 😊

[@sametgumus1281]

Thanks Professor, in one word Great Expression

[@DataProfessor]

Thank you! 😃

[@monroebayer783]

Hello Professor, I am doing the MOa Challenge on kaggle, I will be glad to get some insights from your point of view and experience, regarding, preprocessing, data enrichment, reduce data dimensions etc... thanks

[@jameshizon4861]

How do I prepare for Biology Data Specialist interview?

[@DataProfessor]

A suggestion is to study the context of the interviewing company to see how they are making use of the biology data and based on that, see how you can contribute to the company. Aside from that, depending on the company, you may also want to refresh on the basics of either biology or informatics.

[@jameshizon4861]

@@DataProfessor Thanks! I had an initial phone screen and will have another interview next week. I needed some confirmation :)

[@DataProfessor]

@@jameshizon4861 Awesome!

[@arrowhernanda7361]

Can someone with math bachelor take a master degree of bioinformatics ?

[@DataProfessor]

Math is one of the pillars in data science since you're well versed with this then the other two major components is coding and biology. To succeed in biology, you'll need good problem solving skills and you'll only need a basic understanding of biology in order to understand the data problem. You got this!

[@arrowhernanda7361]

@@DataProfessor I'm actually enrolled on concentration of data science in my math major. Thanks for the information.

[@DataProfessor]

@@arrowhernanda7361 Nice!

[@taseersuleman7343]

Very nice step initiated by you. I want to know the most authentic databases from where we can get Post Transcriptional modification sites data for RNA?

[@sebastiancastro4126]

I wanted to ask about how to apply ML to a selectivity problem in drug discovery. Thanks!

[@hamidkhurshid8161]

You need to look at the toxicity data of the given chemicals in order to apply ML for drug discovery

[@navzali142]

I have recently done my BS in Biotechnology, will it be okay for me to do my masters in Bioinformatics?? As I don't know about computing much...but I am very interested in Bioinformatics,❤️

[@DataProfessor]

Yes, definitely. There's a lot of interesting data to explore in biology and bioinformatics is a great way to apply computing to make sense of the data. It can definitely be picked up during the course of your studies. Persistence is key 😊

[@navzali142]

Hmmmm Thankyou,💕💕💕

[@shaluchand1166]

I want to know about DDBJ sir .....

[@WhyofAI]

Great AMA and really informative Chanin!

[@DataProfessor]

Thanks Alex, this means a lot coming from you 😊

[@elvisnnaemeka6722]

Can someone become a bioinformatician by going through online MOOC courses?

[@yusufbagc6425]

Next time can u answer the importance of spatial data

[@DataProfessor]

Thanks for the suggestion 😊

[@Dazelsea]

I am in india can i be data scientist i have biology

[@DataProfessor]

Yes, absolutely!

[@Dazelsea]

@@DataProfessor yes but i am confused in road map Like what should i do after bioinformatics

[@SurajKumar-on5in]

I wanna learn bioinformatics sir

[@sd-damavandi]

Thanks.

[@DataProfessor]

Thanks for watching

[@sd-damavandi]

@@DataProfessor hi, l love working on the drug design.

[@sd-damavandi]

@@DataProfessor now. I study PCM model.

[@sd-damavandi]

@@DataProfessor do you accept PhD student in Bioinformatics?

[@blahblah4670]

this is super cool !!!

[@DataProfessor]

Glad you're finding it helpful 😊

[@blahblah4670]

@@DataProfessor I'm glad that I have a teacher like you :)

[@purplenirple]

This was a talk on drug discovery and design not bioinformatics.

[@kapilkumar-jn4il]

I have discussed with you