T cell activation and differentiation | T cell development 1

[@samuelmarandi2644]

Thankyou sir !Tomorrow I have my immunology exam and your my last option !Im glad you’ve explained it well🔥🥲

[@shomusbiologyofficial]

You're welcome

[@ajinkya3780]

referring ur videos for study since 2 years & i must say you have improved a lot in terms of video quality and ur looks as well ..great work keep it up :)

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😂😂 are you serious at all😂😂

[@ricasaluria8821]

Hahahah bro code

[@shefnan8794]

🤣🤣🙌

[@JackSpear1000]

Respect 🙏, your videos and lectures are miles ahead of our Faculties.

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@snehabasak4113]

Thank you for supporting us unconditionally and teaching us...... Happy teacher's day sir😊😊

[@shomusbiologyofficial]

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[@minnaadil5657]

I’m a second year and I just found this channel and I want to let you know that it’s been so useful!thank you so much! looks like you’re going to save me my immunology course this semester.

[@vidhisahu9671]

thank u so much sir .....tomorrow is my exam and i was very tensed about this topic bt your video helps me a lot thank u so much sir for making such valuable videos 💞💕🙏

[@shilpabhattacharya3567]

Same even i have my immunology exam tomorrow.

[@samikshasapkota1315]

thank u sir

[@missioncsir-jrf8656]

I have been watching ur videos for the past few months and i have improved my grasp for understanding this subkect by leaps and bounds. Thank you

[@shomusbiologyofficial]

That's good to know

[@haddadmj96]

Hi. My exam is tomorrow and I have you'll answer my question soon. How is Nucleocytoplasmic transport involved in the T cell activation?

[@ayanasudheer2934]

I was so worried about my immunology exams.These videos helped me to get over it.Thank you so much sir.

[@josshy11]

you are an amazing teacher! thanks you for everything! on tuesday is my final exam and i know you will help me :) great work! take care yourself.

[@roshaninale716]

Can't thank you enough! Very very helpful😃

[@gopikagdev1116]

sir, your classes are very simple and understanding. u take classes ina a simple and lucid style .very very helpful.thank you sir

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

[@sabitasinku9548]

Tomorrow is my Immunology paper, Thank you very very Much sir , you are my Lifesaver 🥰🥰🥰love from odisha sir , jay Jagannath , meri ug , pg apke vdo dekh kar hinn complete hogi 🥰🥰🥰🥰😁😁😁clg m kithne hin ache se hinn padhaye but apke jaise koi bhi nhi 🥰🥰

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@beingkrsnaaconscious]

I searched everywhere and your explanation is as good as Najeeb Sir .

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@sarahtorres8640]

This is extremely well taught. Thank you!

[@shomusbiologyofficial]

+Sarah Torres glad I can help. Stay tuned and keep watching

[@lavanyasalian6629]

Can someone help me with sequence of videos.Rn I just completed MHC complexes it's very confusing

[@fathimahumtha1129]

excellent teaching bro!!!!! very useful! thank you soooooo much :)

[@ratnadas5882]

very helpful for microbiology bsc course..thank u sir'

[@shomusbiologyofficial]

You're welcome

[@oceanwaves657]

Thanks for nice lecture. One question is that, which event take place first ; T cell maturation in the thymus or T cell activation ?

[@indradventure]

Very well articulated and presented with perfection. Thank you Sayan.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@gursimran3025]

Sir , What is CD 80 , CD 86 and also CD3

[@sameerapinky2995]

This is a valuable video,,,,,,,complicated topic is simplified within minutes...😃

[@shomusbiologyofficial]

Thank you

[@25zaidparkar84]

thank you Sir, Very well explained and now the concept is very much clear. KEEP IT UP SIR

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@mayukhroy5393]

Sir, thank you so much for this explanation.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@ayaantade5708]

Well done!! Very nicely and precisely explained.

[@shomusbiologyofficial]

You're welcome

[@ayanasudheer2934]

I was so worried about my immunology exams.These videos helped me to get over it.Thank you so much sir.

[@Dirtmazzz]

That is one of the most comprehensive videos explaining T cell differentiation.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@alokmonispkm4016]

Apnar videos deke ami Biology ta aro easy bhujechi jeta ami School and college time e bhujte parini. Thank you Dada

[@shomusbiologyofficial]

Dhonyobaad.

[@renukamaharjan3483]

sir can u provide some clear info about positive and negative selection of double positive tcells

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@supreeti_banerjee10.9]

Thankyou sir....this video helped me lot

[@shomusbiologyofficial]

You're welcome

[@dipasvilla2087]

Sir yr videos are sooooooooo helpful for understanding each n every topic without confusing them..really so helpful plz make more n more videos on microbiology topics..

[@shomusbiologyofficial]

+Dipali Ambe thank you. Glad you liked my lectures

[@amanita8481]

you have been incredibly helpful in summarizing this without sacrificing important detail. thank you :)

[@manisharauthan3142]

sir i like your all videos... but pls i requested you make a new video drug eruption (fixed drug eruption)... thanks

[@thedentilancer01]

Sir.... A doubt. The book sembulingam says that the macrophage releases interleukin 1 and not 12.... In fact helper t cells don't release interleukin 1 as u said.... So pls clear it, which one to go with.

[@aparnajangamgari8347]

Tqq so much Sir for explanation

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@lukasphiri7529]

thank you munthu wanga

[@wycliffenyandika9017]

hello sir! thank you for viseo. i have a quick question ,am a little lost around 5:42 min,if they ID as foreign,will not engage in the activation process and if they recognize them self material-will never activate immnure system,if immune system is not activated agaisnt self why is it a BAD thing and how does that Relate to autoimmune,thought for auto immune to occur the immune system has to be overly reactive to self?? this concept of positive and negative selection keeps confusing me every time i think i undertand it

[@nahumnahum4779]

You are awesome. Thanks a lot for the explanation

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@meenuvip974]

Your explanation is so simple and easy even a person with no science background can understand.

[@shomusbiologyofficial]

Thank you

[@drssherpa]

IL-1 is not produced by helper T cell brother, plz correct it. Its always produced by macrophage

[@bedatrayeebarman674]

Sir Is APC - T cell interaction and t cell activation same???

[@juhibohra341]

Those who dislike the video they are haters and don't want knowledge .I want to say that for making a video much more hardwork is required .🤔🤔🤔😇😇😇

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@fiddleleaf9336]

This video was really helpful. Thankyou so much!

[@shomusbiologyofficial]

You're welcome

[@toknowhim9498]

Am following you anna for my gaining knowledge I thank y To you and ur team thank u so much Bro.

[@dreamlike5659]

Bro you are AWESOME!!!! Thanks a lot, and keep up the good work! Love you man really! (not gay, just saying :D )

[@leelavattikuti8247]

Sir plz tell me how to body .immune system attack and killed poliovirus

[@subhashree4869]

Sir ur video get all basic things ur video is very important undoubtedly ur somewhat my inspiration 🙏

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

[@niranjannayak6149]

Thank you so much sir♥️♥️

[@shomusbiologyofficial]

You're welcome

[@muhammadalaparsalan5001]

Love you sir 💕💕💕❤️❤️❤️😘😘😘😘😘

[@shomusbiologyofficial]

Thank you

[@TheMusicalDoc]

Very helpful! thank you :)

[@wonderingmerchant]

Mr.Shomus help me understand immunology in a broad but simple way. Very helpful for my undergraduate program

[@shomusbiologyofficial]

Glad it helped

[@sobster123]

wow Shomu. n I thought I knew the process. But nowhere near enough as detailed as this, it makes so much sense now, thank you.. you're the best!!!!!

[@shomusbiologyofficial]

+sobster123 glad to hear that. Please subscribe and share

[@eishamaryam2775]

Finalllly i got the concept 🥺

[@shomusbiologyofficial]

You're welcome

[@Farhab]

great..... but, better if you donot (decreases) cover the screen by your face, and show white board....

[@shomusbiologyofficial]

Okay

[@maryjoe6918]

Superb presentation. Congrats Shomu and thanks

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@bharatnagesh9859]

I think , Interleukin 1 not produce by TH cell

[@nahar6928]

You are a great savior for the graduation students sir 😭,really appreciate your hard work.

[@shomusbiologyofficial]

Thank you

[@abel4148]

For how long u r going to save my life 🤔🤣

[@shomusbiologyofficial]

Years and years to come

[@Lovefornature555]

You are superb sir.. Thank you once again

[@shomusbiologyofficial]

You're welcome

[@405shruti7]

Where is T cell differentiation Video ?

[@saloni2496]

Thank you sir your videos are great!!!💐

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@pritamdas3066]

Thank you sir,you are really good teacher..♥️♥️♥️

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@mathumitha6340]

Which video is after this topic... Pls tel me sir

[@bhartiwagh2189]

Very helpful... Amazing👍👍👍👍 Can you share te vedio of role of macrophages in periodontal inflammation and periodontal disease please....

[@drjavaidiqbalmir767]

Sir thank you very much for this lecture..I have a confusion..Actually that is a receptor on macrophage not MHC on which you have shown antigen..MHC checks whether antigen is attached correctly or not and also is a sensor for CD4 molecules..

[@abhapratim4740]

Thank you so much sir.

[@shomusbiologyofficial]

You're welcome

[@foziafayaz2555]

❤

[@loveyahshayah8855]

Easy learning 🤓🏄🙏

[@shomusbiologyofficial]

Thank you

[@SuPRiyAsInGh-mS]

Thank you very much sir your this lecture also helped me again as always it do..

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@manuelalmendarez2232]

I like that you give the most important information,unlike others but noone including you gives the important details.

[@deepanjalisharma1266]

Your video is very helpful to understand the concept

[@shomusbiologyofficial]

You're welcome

[@basharhamoudeh1563]

They should clone you and distribute your clones to the worldwide

[@shomusbiologyofficial]

+Bashar Hamoudeh why?!!

[@basharhamoudeh1563]

Dude you're epic ! you really explained it better than my prof. !

[@omnarasimhaprasad4213]

Osm teaching sir

[@shomusbiologyofficial]

Thank you

[@bestofluck2754]

Good But Hindi miduum m Lacture

[@sawsanelgohary3188]

i have a question please does it goes the same if it is B cell instead of macrophage? , does B cell have also B7 ???

[@alaawessam7931]

are macrophages,dentritic and b cells the only antigen presenting cells from white blood cells

[@shomusbiologyofficial]

Yes

[@gursimran3025]

What is zeta chain

[@gursimran3025]

Sir I can't understand please help

[@NazmulHasan-oj5ow]

You best sir🔥

[@shomusbiologyofficial]

Thank you

[@sanjoyrudrapal2344]

Excellent video

[@shomusbiologyofficial]

Thank you

[@nareshdaokala2760]

thank you sir

[@shomusbiologyofficial]

You're welcome

[@saminurr5793]

Sir what are the gene involved in T cell activation?

[@sanathpremathilaka2504]

Thanku sir😭🙏love u❤️

[@shomusbiologyofficial]

You're welcome

[@payalrawat4119]

lacking of T cells which diseases a pesons suffering from

[@shehrinshaikh3926]

Excellent 👏

[@shomusbiologyofficial]

Thank you

[@emanothman9665]

Thanks alot so helpful but i would like to understand biochemical pathways of t cell activation ... i know it could be easy if you give lecture about it

[@fahimalamnobel4789]

When pathogen entered into the body, the macrophages, engulf it and represents the fragment part outside. If this same process will be done by dendritic cells? I mean T-cell becomes activated by the presentation of antigen by the macrophage. A dendritic cell is also an APC cell. So is it possible to continue the whole process by the dendritic cell? The same signalling molecule act on it?

[@shomusbiologyofficial]

Both acn do. Dendritic cell Co tacts the adaptive immunity

[@fahimalamnobel4789]

@@shomusbiologyofficial Sorry sir i am not understand the answer properly. Can you plz elaborate it?

[@sayantansaha53]

Very easily explained

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@sayantansaha53]

Welcome sir

[@pranjalimahamuni-badiger2873]

Excellent

[@shomusbiologyofficial]

Thank you

[@ricasaluria8821]

What does IL 1 FUNCTION AGAIN SIR

[@vinaykamal9049]

Well done

[@shomusbiologyofficial]

Thank you

[@faisalahmedshariff6109]

Kabhi Kabhi lagta hai ki Suman-ich bhagwan hai xP

[@shomusbiologyofficial]

Ha ha

[@leelavattikuti8247]

Sir after maturation naive cd4+ t cell leave the thymus and enter the secondary lymphoid organ, need to activation for( own self antigen presenting cell) or pathogen

[@shomusbiologyofficial]

Yes

[@leelavattikuti8247]

@@shomusbiologyofficial sir it's virus pathogen or own self antigen presenting cell?

[@mohammedkamel8988]

Nic I am from Afghanistan ples I wan. Mor like this

[@manimaran-ov2fb]

It is not IL 12 it is IL 1

[@nuhusati5901]

I so much enjoyed infact benefit on your video lectures. Tom up👍👍👍

[@cristina90324]

thank you!! amazing video

[@shomusbiologyofficial]

You're welcome

[@kwagaladorcus1198]

Well explained, thank you

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@priyankasatapathy4146]

Tutorial on Regulations of B and T cell... Plz

[@pamelaijeoma8199]

Thank you. This was so helpful.

[@shomusbiologyofficial]

Glad it helped

[@amisharastogi9109]

👌👌extremely good

[@vgt185]

Hi sir, How I can explain that question?"It is vital to understand that both Th1 and responses are important in the task of protecting the host against infection. responses are antagonistic"?