Will I need Chemotherapy for My Breast Cancer?

We teach you how your tumor receptors, lymph nodes, genomic assays, and breast cancer stage indicates if you would benefit from chemotherapy.
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Questions for your Medical Oncologist and Breast Surgeon:
1. Would I benefit from chemotherapy?
2. What factors suggest I will benefit from chemotherapy?
3. What is the risk to my life if I do not undergo chemotherapy?
4. What are the advantages of “Neoadjuvant Chemo” before surgery?
5. Would a “Genomic Assay” help determine if I need chemotherapy?
6. What is chemotherapy?
Chemotherapy is the use of certain medications to treat cancer systemically, meaning throughout the whole body. If needed, chemotherapy is usually given after surgery for invasive breast cancer. It is a more intense cancer treatment than hormonal therapy (usually pills). Only a minority of breast cancer patients will ever need it. These complex decisions are ones you will make with your medical oncologist. You will make better treatment choices when you are informed about chemotherapy and hormonal therapy before meeting with your medical oncologist.
General indications for chemotherapy
We outline below some of the more common indications for needing chemotherapy. The decision to undergo chemotherapy also involves being healthy enough to tolerate the treatment. Deciding who needs chemotherapy and what type of chemotherapy to administer is one of the most difficult decisions made in medicine. Your medical oncologist will guide you.
Do my “receptors” suggest I need chemotherapy?
Once a breast biopsy is found to be cancerous, the pathologists will automatically run more tests on the same tissue to determine what “receptors” are expressed. Your receptor pattern is a key piece of information that comes early in your breast cancer journey. In about 30% of patients with an invasive breast cancer, the receptor pattern alone can strongly suggest that chemotherapy will be needed regardless of what is found at surgery. The key points regarding receptors are outlined below.
Estrogen Receptor Negative (ER -) tumors (20%) do not respond to anti-estrogen oral medications that are essential in treating estrogen receptor positive (ER +) tumors. Quite simply, patients with ER negative tumors will benefit from chemotherapy if they are healthy enough to tolerate it. ER negative tumors are more aggressive cancers, but respond more favorably to chemotherapy than ER positive breast cancers.
HER2 Receptor Positive (HER2+) tumors (20%) are very responsive to chemotherapy when paired with new breakthrough drugs that target these tumors, such as Herceptin and Perjeta. The same holds true even if a HER2-positive tumor is also Estrogen Receptor positive (ER+). HER2+ tumors are more aggressive cancers, but we now can treat them more effectively with chemotherapy and new drugs that are “targeted” to destroy HER2-positive cancers.
“Triple Negative” (ER-)(PR-)(HER2-) tumors are fast growing tumors that are usually treated with a specific chemotherapy regimen. These tumors are not responsive to hormonal therapy at all, but may be sensitive to chemotherapy.
What if cancer is detected in the lymph nodes?
If you have “lymph node positive” breast cancer, it is likely you will be offered chemotherapy. Premenopausal women and those with multiple “positive” lymph nodes generally benefit from chemotherapy. If your breast surgeon detects cancer in your lymph nodes before surgery, there may be specific advantages to undergoing “neoadjuvant chemotherapy.”
“Inflammatory Breast Cancer” requires chemotherapy
If you have been diagnosed with inflammatory breast cancer, the first step is neoadjuvant chemotherapy before surgery. This type of cancer has a high likelihood of spreading to the lymph nodes and other parts of the body. Starting chemotherapy as soon as possible is essential to treating this aggressive breast cancer. A mastectomy is performed after chemotherapy, followed by radiation to the area of the mastectomy to lessen the chance of cancer growing back in that area.
What are the advantages of “neoadjuvant chemotherapy”?
Neoadjuvant chemotherapy is when chemotherapy is given before surgery, not afterwards. There are specific advantages to neoadjuvant chemotherapy in appropriately selected patients.
How can a genomic “Oncotype DX” test be helpful?
Patients who have a small, estrogen receptor positive, HER2 receptor negative tumor and no evidence of cancer in their lymph nodes may benefit from an Oncotype DX genomic assay. This cutting-edge test looks deeper into breast cancer cells to better identify people who may benefit from chemotherapy with ER+, HER2 - breast cancers.

[@Rampaigee]

I declare healing for every one diagnosed with breast cancer in Jesus name! 🙏🏼

[@hawanatuhawanatu5857]

Can u help me with priscrition for my mother.she have breast cancer

[@katgabrieles358]

🙏 amen god’s grace

[@Aduhh33165]

@@hawanatuhawanatu5857 bro.. I adv u take her to oncologist in hospital.. they were the expert.. chk and investigate her healthy condition any..if possible avoid her eating foods that contain artificial sugar and meat..more broccoli.. cauliflowers. all berries except cherries.. promegranate fruits also good...

[@KaNutty77]

Amen

[@CandiceBradleyPhD]

Cut it out.

[@alechamid235]

This is a REAL doctor, I love the way he explains things. So easy to understand.

[@ktakea76]

This whole series is extremely helpful. Whoever thought to do this needs multiple awards. I wish similar things were made for more conditions. And I absolutely agree that the doctor is extremely talented and articulate. He does a great job with the videos - he’s credible, personable, and warm. The scripts are well written too. There has to be a team putting this together, though. I’d love to see how the roles break down!

[@clarissllena1501]

I'm newly diagnosed breast cancer. Thanks for the best info I learned Doctor

[@hoopstv9140]

im praying for your fast recovery and healing. My sister will have her CT SCAN tomorrow. Hoping that everyone will be cured.. :)

[@slogenblake4283]

Thank you so much for this video presentation. I am one who is a breast cancer in 2021 and it was stage 2. After 6 cycles of chemo and went in for mastectomy. I am beginning to understand all this presentation you have put. My doctors were never vocal and advisable. I wish I can get the best treatment from your end for the sake of my children. Thank you for all these information 😊

[@TheHighPriestessStudio]

What a lovely bedside manner, thank you for explaining things so much better, I wish other Doctors spoke so kindly. I wish you were my Doctor. Prayers to those going through the same. ~Karen🌹

[@BreastCancerSchoolforPatients]

Thank you High Priestess! Make sure to visit the Breast Cancer School for Patients with all the other information you need to know about breast cancer. This video is just one of 60 at the school. www.breastcancercourse.org

[@TheHighPriestessStudio]

Thank you I'm watching and learning so much, I've just had another biopsy and awaiting those results. Sigh, it never rains but pours, so far I've had a tumour removed from my stomach which ended up I lost 85% of my stomach and my pre-op surgery for the bowel is next week.. I'm keeping positive as much as I can, but felt so ill informed. Thank you Dr John. ~Karen🌹

[@nicolerosenah933]

M recovering from breast cancer surgery stage 3c😥😰😓😓😓

[@nicolerosenah933]

@@TheHighPriestessStudio keep being strong

[@MarnieClarkBreastCancerCoach]

Very well explained. I just wish this information had been available in 2004 when I went through breast cancer. My second wish would be that our doctors be taught more about the role of nutrition in helping us to survive breast cancer.

[@sheebasebastian5874]

You are correct .Nutrition and life style changes will help. Try to live stress free as possible .

[@bomb_shell8406]

I’d love any info or links please on nutrition..

[@evansnyangau9725]

My mother as been diagnosed with breast cancer stage 4 which kind of food should employ, kindly in need urgently.

[@debbiec2663]

I am so thankful for your videos. Your education has helped to get educated, so I can focus more on what my dr is telling me versus focusing on the fear of the unknown. God bless you and thanks a million

[@jamiecalvert9242]

Thank you for making videos like this so people can make informed decisions.

[@yvonnequinones3972]

I cried and hugged my oncologist when my OncotypeDX number was a 9. He told me the mastectomy was my cure. Grateful and blessed.

[@manalabidy5635]

What about lymph node positive or negative ? Are you above 40? I have1 lymph node and my score 5

[@MizzClecle]

They said the same thing for me as well! 5yrs ago had a Double Mastectomy. Now one ☝🏽 lymph node is hot on the Pet CT

[@jannulik]

Why are you calling yourself blessed if you were going to have mastectomy?

[@sashagirl1987]

My onco type was 22, my oncologist said I didnt need chemo. She said had my onco type been 25 or higher I would have needed chemo. This is all so confusing and I pray we did enough for my cancer. I was diagnosed with stage 2 ductal breast cancer my tumor was 6 cm, the size of a golf ball we could literally see it protruding from my breast. I still worry every single day. Prayers for everyone facing this awful disease 🙏🙏🙏

[@sumaya4649]

@@sashagirl1987same as my oncotype but they gave me 4 cycle of chemo they said there is 6.5% Benfit and my tumor was 2 cm

[@ishouldbesleeping1354]

I was offered Chemo and I couldn’t do it. I work a very physical job one on one with people and no else contributes to my support, or would be able to care for me during treatment so I said no. Another lump came up near the lymph node they removed last week, and now I’m under duress. Please pray I make good decisions and can overcome my anxiety and obstacles.

[@BreastCancerSchoolforPatients]

Good luck on all of this. Make sure to visit the formal Breast Cancer School for Patients at www.breastcancercourse.org to learn more.

[@donnawolfe8682]

Gloria Newton happen to see your question. I’m having lumpectomy on 7/25. I have DCIS early stage. Pretty sure will have radiation. But doc already mention chemo. I feel I must draw line at chemo and say no. I’ll be 73 in Oct. Right now I am sad, depressed, basically a wreck. But wanted to say good luck to you.

[@akmalibrahim4587]

Good luck... my mother also dont want to do chemo..my world is upside down right now

[@ferminmonica2670]

donna wolfe weird for that you don’t need chemo

[@yenski2012]

@@donnawolfe8682 how are you now? Did u go thru chemo? I was also dx with dcis i am only 47 now

[@vibes811]

Such a peaceful being he seems❤, very comforting for the eye&ear👌

[@Talal1602]

Thank you so much for all your ' lesons'. It helps me a great deal in this proces.

[@BreastCancerSchoolforPatients]

Thank you for the feedback!

[@elizabethstephens3007]

Quick recovery . We shall conquer

[@elizabethstephens3007]

We are going to get through it kzbin.info/www/bejne/bqSYYY2eash7ga8

[@elizabethstephens3007]

We are going to get through it kzbin.info/www/bejne/bqSYYY2eash7ga8

[@SwrPwr]

God bless this Dr Williams for his knowledge and his great personality.

[@CariSalgado]

My mom just got diagnosed with stage 2 . We have a Dr appointment soon for the first time after she found out. I’m getting prepare for her Dr visit and thank to all this good information, now I have a good understanding of this and what to ask. THANK YOU!

[@habibi7791]

Cari Salgado How is your mom now ?

[@kaleidoscope1173]

How is your mom doing now? Any update?

[@do9138]

She's lucky to have you. I was just DXed with stage 2, and I have no one to help me with anything.

[@2studiosinc62]

@@do9138 , I will pray and ask God to send legions of people to help you. 🙏🏽😊

[@JoeJoe-pp8rv]

@@do9138 hows it going tell me

[@janbers8025]

thank you for this information Doctor. its a great help!

[@jeansperbeck1672]

This is wonderful information, thank you

[@barbaragay8109]

This is excellent information to understand the concept breast cancer. Thank you

[@georgieprice3640]

I have just got my results today my the lump was cancer's but non on my limp bones dose this definitely mean the cancer hasn't spread good luck to all who's reading this x

[@patriciaransome623]

Thank you for the clarification.

[@KTen-cm6wx]

Dr.Williams what a gift from God. I am 71 n just had a lumpectomy. I was positive for Estrogen n Progesterone. Went back to my surgeon to have stitches out n only saw her nurse. I have so many questions I wanted answered n wasn’t able to see her. I’m mad, upset n feel this was wrong of her to be done with me. What should I do?

[@sashagirl1987]

This seems so negligent. I’d call and make another appt with the DOCTOR and tell him/her you NEED info and guidance. I’m so sorry you were treated that way. Unacceptable. Praying for you. 🙏 I was diagnosed with stage 2 ductal BC on July 23, 2020 and had a double mastectomy on sept 2,2020. I did not require chemo but am on hormone blockers for 5 years. But I worry every day IF my Doctor did enough for my type of cancer. It’s all SO confusing and I think a lot of Doctors forget we don’t know what they know. I so hope you get more answers. 🙏

[@KTen-cm6wx]

10 months later I still have some pain n lymphdema. The left breast has a small lump but mammogram said it was ok.

[@SCLana]

Thank you, I am going to talk my doctor today because I am thinking I don’t need a chemotherapy. I had surgery already.

[@sp6726]

Thank God for you, Dr. This video explained my situation exactly and is helping me decide whether or not chemo is right for me. Genomic assay portion was very helpful.

[@elaineyaz6451]

Thank you. You are very reassuring.

[@gumbasiz]

Could you also mention Ki67 antigen proliferation or compared it with genomic assay ?

[@a_z9174]

what are the usually used cytotoxic chemotherapy for breast lumpectomy ? is it superior to radiotherapy ? if a patient took her first course of Adriamycin + cyclophosphamide and developed severe gastric pain on the second day not responding to proton - pump inhibitors , antiemetics as ondansetron + metoclopramide and antispasmodics , then on 3rd day admitted to hospital as a case of gastric bleeding and managed conservatively , now what should be done for the second course ?

[@drkhinswe2]

Thank you

[@do9138]

According to videos by women who are having treatments, the side effects of chemo can be debilitating, including headaches so bad they have to wrap their hairless heads in ice. Hormonal therapy is even worse. Women say their joints hurt so much they can't walk, and that lasts for 10 years. I am ER+, PR+, HER2+. But I am 66. I doubt I will get chemo if I can't do it orally, and I'm pretty sure I won't do hormonal therapy. It's about quality of life at my age.

[@khaliddurrani6432]

As a student of surgical oncology I am intrigued by the colossal amount of money pumped into the research for more and more toxic and expensive systemic therapy as well as its publication & promotion by the big Pharma whereas so little if any endeavor is made on the prevention of this malady.

[@monicag6715]

That’s why I refused it. I’m taking vitamin C IV. F the cancer and pharmaceutical industry

[@jyienger]

You are correct. It's an industry first, science second....

[@ktakea76]

Well, not everything can be prevented. I don’t have any problem investing in research for treatments. Quite the opposite. I do have a problem investing in ineffective - or only marginally effective (and yes, very often highly toxic) - treatments that are usually SIGNIFICANTLY more expensive than drugs that have been on the market for decades.

[@BubbleBurster-nv1vl]

@@ktakea76 Take BCG for bladder cancer. It's been around for at least 40 years. It's really TB to awaken your IMMUNE system instead of destroying it with chemo. I am in remission for over two years thanks to BCG immunology treatment. It sure beats robotic surgery every three months!

[@juaquiene7726]

Your comment sure rang a bell for me. I cringe when they call it Chemo Therapy. Or a medication. Get real. Quit patronizing patients call it what it is. Chemo toxin. Crap works by being poisonous.. Like holy 💩 your hair falls out. You look 10 yrs older. Exhausted, diarrhea, nausea can't finish a thought or sentence. Wonderful stuff. 😢

[@IndeEyeLavanya]

I didn't have to go through chemotherapy. I sent my tumor blocks for Oncotype DX test and results said chemotherapy will least be beneficial to me.

[@JeffreyWillis800]

So one thing I am wondering here is, when is it not a good idea to do chemotherapy. I seemed to have not understood in this video, but it seems very basic and good and I love the way you have explained it. And is this info still good for 2021? Wife has stage 4 breast cancer and treating with Virginia Cancer Specialists, put on letrazole and ibrance and an estrogen blocking injection to push her into menopause. But having very difficult side effects for her, and wants to quit after a short time.

[@JeffreyWillis800]

Her cancer is estrogen dependent, not HER2, and genomic assay shows letrozole works.

[@christineanderson487]

@breast cancer school i have IDC and i want to know if i can just get a mastectomy and radiation???. i have only heard horror stories from people who did chemo.they were so beat down the chemo killed them or they became suicidal and died

[@jayzkatinapi562]

new to breast cancer, do the chemo helps or natural herbs help

[@mikedeegan9342]

Thanks

[@M.Saud786]

If a female At age 74 have breast cancer stage 3 & after removal of breast what is beneficial treatment next? If cancer not affect bone or any other part of body.

[@TheBubbleBia]

Hi Dr, do you offer online consultations?

[@JackyHapy]

Thank you for this so easily digestible explanation. You have a wonderful way of delivering even the "hard to hear" information. Appreciate. 🙏🏾

[@debbieroberts600]

I was Diagnosed with Invasive Ductal Carcinoma Breast Cancer, ithe Tumor was under My Armpit, had Surgery to remove Tumor, they took out 13 Lymph Nodes! Then had 7 Weeks of Radation! Should I have been given Chemotherapy also? The Radation Man was Suprised that my Cancer Dr. didn’t Prescribe Chemotherapy Also!

[@JeffreyWillis800]

So if my wife's oncologist at Virginia Cancer Specialists has not ID'd her for chemo, but has given her estrogen blockers and Ibrance, can I rely on them to have made a good decision on that? Or do I need to ask more questions. Sorry to be so direct, but I have a 5 year old son that loves his mom, and I can't explain if I screw this up and lose her.

[@Rebecca23434]

Praying for healing, strength and mental peace for your family 🙏🏾

[@sadanandrapolu8836]

I have tnbc with pregnancy 21 weeks taking chemotherapy is good for baby? Will survive with chemotherapy please advise me

[@shantybryant4452]

My aunt has stage II cancer after a lumpectomy it still is in the lymph nodes..she doesn't want chemo..will Hormone therapy be easier for her since she still wants to keep her job and be active in life ..your videos are the best info was explained in simple terms

[@user-mq8oo2zv1f]

How about ER+1 , PR - and Her2 > is chemo needed? Currently doing 21 cycle radiation therapy

[@1979hellcat]

I was diagnosed w stage 2 HER2 triple positive breast cancer- estrogen, progesterone, n HER2 positive receptors. I’m doing chemo b4 surgery n it’s not yet in lymph nodes, but has grown since biopsy by a lot. 😞

[@kaleidoscope1173]

How are you doing now?

[@lifewithislam2023]

How can I contact you for advise as I am patient of breast cancer and had mastectomy last month.

[@auntiechihera8665]

@@maryanne8407 where is the store or contact

[@1979hellcat]

My next question: since I’ll be losing one breast - cuz I’m small breasted, n the tumor is like half my breast size, n they want to put me on estrogen blockers, n BRCA genes can cause me to possibly have ovarian cancer, would it make sense to not do the estrogen blockers n get a full hysterectomy??

[@kristinreese2281]

I was told by my surgeon that you would still have to take the blockers because estrogen is produced ( in smaller amounts) by other parts of the body.

[@MM-vh1bx]

Doctor my question is how long does it take for the cancer to grow and discover it ?

[@2studiosinc62]

Seven to ten years.

[@sajidaparveen9074]

I am a patient 4 stage cancer breast my doctor advic me 18 chemotherapy

[@sree9302]

How is now

[@laurelmcara6544]

You are the best doctor on YT,wish you were mine.

[@harishgoyal3526]

what treatment needed if ER+ PR+ HR2- AND CANCER TYPE IS DUCTAL NOS .and all 16 lymph nodes are negtive for metastasis. Pls suggest us

[@aaryan9683]

How you doing today

[@arunkhajuria8511]

Harish goyal @ I hope all well..kindly tell us which treatment u taking

[@kizzelcazsscx]

What is mean by ER+PR+HR2

[@suaadiskander934]

What your treatment please -hope not chimnothurpy

[@tigertiger3872]

@@kizzelcazsscx Means estrogen positive, progesterone positive and Her2 negative they are hormones who feed the tumor to grow.

[@suzannecrawley9840]

Her2 positive 1.5cc Taxol and Herceptin treatments will I ever be the same.

[@aribernays]

Hi Suzanne, Someone I love is in the same situation you described in your comment here from 1 year ago. How are you doing since this past year? I hope you’re doing well. I wonder what you thought of the treatment? any info would be much appreciated. But obviously no pressure if you’d rather not :) Thanks sweetheart 😘

[@michelleMYHELL5244]

I wish you were my Doctor:(

[@BreastCancerSchoolforPatients]

You are too kind. I hope you found the concepts in the video helpful. I am sure you are in good hands.

[@shahenahmed5102]

My wife has triple negative breast cancer one year ago she had a surgery it has spread everywhere what is the best treatment

[@gangadhargunaki2144]

The protocol suggested by Dr.Khadar valli may followed. I am witnessing his protocol. It's working.www.sirijeevan.org/protocols Stop eating wheat,rice,milk & sugar immeadiatly.

[@maryanne8407]

Use Dr Omo herbal medicine very active..

[@claritzamarmolejos6803]

How is she

[@Pakistankikhana]

@@maryanne8407 where to get plz

[@susiepingleton3614]

Oh chemo is crammed down every patient’s throat!!

[@rlbrown4013]

With my experience, Dr Winnie Henderson, is the best surgeon in Eugene Or.

[@pramodnagar9883]

My mom operated bcs stage 2nd...with axillary lymph nodes. Is chemotherapy need her plz reply???? Her report is....er pr positive Her2 negative Lymphovascular seen PNi seen What is treatment plzzz Help..🙏

[@petitedoll766]

Did she had to do chemo

[@pramodnagar9883]

@@petitedoll766 yes chemo and radiation has completed

[@petitedoll766]

@@pramodnagar9883 how much round of chemo and radiation did she had to do

[@pramodnagar9883]

@@petitedoll766 4 chemo 2 radiation

[@petitedoll766]

@@pramodnagar9883 did Ur mom lost her hair during chemo

[@francisbernardes6524]

what to do? my grandma has stage 4 breast cancer

[@loyalson135]

I was diagnosed of CANCER in 2016 and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including CANCER, at first i doubted if it was real but decided to give it a try , when i contact this herbalist via his email and he prepared a CANCER herbal cure and sent it to me via UPS delivery company service, when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 21 days of usage, I am now free from the deadly disease called CANCER, all thanks to Dr. Ayemere you can reach this great herbal doctor via call or WhatsApp him [phone] or email doctorayemereherbalcure@gmail. com He also have the herb to cure: (1) ALS, (2) DIABETES, (3) HIV&AIDS, (4) URINARY TRACT INFECTION, (5) CANCER, (6) HERPES (7)HIGH BLOOD PRESSURE (8)fibroid (9)Pregnancy (10)Tubes block(11)kidney disease (14)Heart failure (15) S.T.D

[@francisbernardes6524]

Thanks guys but thank God my grandma survived the surgery :))

[@albertinamujawamaliyaa2069]

@@loyalson135 c""ccccccc" cc""" v

[@sree9302]

@@francisbernardes6524 How is now? What is her treatment? Is it spreaded it anywhere in stage 4? Please reply

[@amenabebe4999]

I’m newly diagnosed breast cancer I’m just scared 😟

[@hoopstv9140]

dont be there are a lot of medicine to use. I will advise you to have your ctscan to know more about the cancer cells. My sister will also undergo ctscan and we are hoping for the best and for the healing of everyone

[@amenabebe4999]

@@hoopstv9140 🙏🏽

[@chandanijain6256]

Sir breast nikalne k bd bhi chemo krana jaruri h agr ni kraye to kuch side effects hoge kya plzz rply

[@MM-vh1bx]

My question is if chemotherapy is to kill any cancer cells spread in the body then why we also took radtion after the surgery. That means that chemo is not enough to kill any cancer cells left in the body. ?

[@phoenixvideos2]

Chemo Spread all areas blood Flow & Kill wherever cell is Radiation often limited to sites only some time One ttt contradict Some time both give for Aggresive ttt

[@goutambaidya5830]

If Stage 2 brest cancer need cemo therapy?

[@inderjitsidhu1938]

If stage 2 type breast cancer needs how many cheoms

[@aahanaandpushpa3965]

6 chemo

[@sandrajagroop9750]

Any lymph node involvement?

[@patriciaransome623]

In Jesus name AMEN...

[@alauddinchowdhury1119]

I’m living Trenton Nj this area needs Md.and address or phone number.

[@suzannecrawley9840]

Where were you when I needed you.

[@BreastCancerSchoolforPatients]

You are very kind. Every person's treatment journey is unique and frought with ups and downs. I am confident you will endure.

[@EL-vw3xj]

Please remove the unnecessary background music. It is distracting and I cannot focus on what is being said.

[@jphickory522]

Agreed

[@turnofcrosssplayonxbox1582]

Cannabis helps and treats cancer and 20,000 other problems

[@BubbleBurster-nv1vl]

No marijuana does nothing to help cancer. In fact smoking a joint damages your lungs similar to cigarette smoking.