C15 Fats: What No One is Telling You [7 Studies Later]

[@Physionic]

Here's my video on C15 vs Omega-3: kzbin.info/www/bejne/qae4qGuGoreloMk

[@brianwnc8168]

Thanks so much for listening to us commenters and putting this out so quickly. I'm impressed and grateful

[@internet1953]

Thanks, Mr. Verhoeven, but you didn't look into the latest publication of the producer of C15, www.ncbi.nlm.nih.gov/pmc/articles/PMC11279173/ which in my opinion is a very important paper, albeit a hypothesis, because it explains the mechanism. It shows the connection between C15 deficiency and ferroptosis, which you don't even mention at all, which is key to understanding why C15 makes you live longer. And ferroptosis is linked to so many diseases, like fatty liver, diabetes, CVD, dementia, and auto-immune diseases, to name a few and also causes the death of mitochondria. How can you miss that? Just look at the picture in the study, it simply explains how this works, so everyone can understand it. The paper also shows which fish is high in C15. So, because C15 prevents ferroptosis dolphins and humans can live so much longer, but there are other ways besides C15, that prevent ferroptosis, like having high levels of glutathione in the membranes of cells and mitochondria. There are so many ways to raise glutathione, just Google it, but an interesting way is getting Near-infrared light from the sunlight or from NIR lamps, which makes melatonin in the mitochondria, which restores Glutathione. Also, vitamin E blocks ferroptosis but not the synthetic version you find in most supplements.

[@mariedenoyer2173]

Thank you, I emailed you about three or four weeks ago and the information is finally presented. Thank you so much!

[@Eevee-s3u]

I don't know. There is a lot of new data coming out on C15:0 and to be honest, the benefits of this molecule are looking very promising. I am now testing my patients for C15:0 levels and finding that they benefit from levels above 0.2% of their total fatty acids. Just one docs opinion... but I believe this will ultimately become the standard of care.

[@lauraw.7008]

Just my personal opinion; I enjoy looking at your face & listening to you talk…and your self-deprecating humor!

[@virgilkirschner5717]

Appreciate this research more than you can imagine. I was ready to reorder the C15 and now I will save $. That money might be sent in for a subscription to your very informative research platform. Thank you ❤

[@Physionic]

Hey, thanks - I appreciate it a lot. :)

[@kathydefilippo8085]

Going to end mine. Thanks!

[@BenjaminKuruga]

@@kathydefilippo8085 Why are you ending it ?

[@carlr2837]

@@kathydefilippo8085 I was going to end mine, because I didn't "feel" any different. Yet, I looked at my lab results, and my liver enzymes are all improved, and I just realized that I don't have any seasonal allergies this year. I think I will continue to take it awhile.

[@angelacollier9256]

Why not just get it from its natural sources?

[@darinl848]

i remember how doctors and scientists (many) fought omega-3 decades ago and now you can get it as a prescription.

[@Voidedsoul]

The studies may not back the claimed benefits but having been taking C15 for about 3 years now I can say it has absolutely made a positive change in my life. Also 90 days is not long enough to see a major change, I didn't start feeling a big difference until 9+ months. It's not a magic quick fix, your body needs time to heal. I get that this is a "trust me bro" claim but I will always supplement with it. The improvement in my health has been that big.

[@Physionic]

Thanks for sharing

[@ExtaTer]

You sound like a rep claiming "benefits" without specifics.

[@Voidedsoul]

@@ExtaTer If I was a rep why would I downplay the studies being used to sell the product? He said so far there aren't any studies to back it and I'm saying the studies weren't long enough. Believe what you want, I couldn't care less if you try it or not. It works for me and that's all that matters.

[@ExtaTer]

@@Voidedsoul "It works for me" without specifics is a typical rep tactics because then people can't refute it. You did it twice so either you are a rep or you are trying to convince yourself that "it works" without having a clear idea in what exactly. In both cases, your account counts as -1.

[@Voidedsoul]

@@ExtaTer I know how but this is a KZbin comment. I'm not going to go into the specifics because I don't need to. All I was doing is sharing my experience that it has improved my life. Buy it, don't buy it, I honestly couldn't care less. Have fun with your comment crusade 😘

[@Leto2ndAtreides]

Side question: Should it really be: "C15 vs Omega-3"? Given the different mechanisms by which they work, they could be complementary.

[@raykinney9907]

More than 'could', likely.

[@mistermiau9949]

dokładnie, każdy wykonuje określone zadanie, faworyzowanie to cecha ignorantów

[@OTatime]

Thanks Nic! You always provide insight and application in an accessible manner for non-scientists without compromising analytical rigor. You are providing a valuable service to your viewers.

[@Physionic]

Thanks :)

[@wonkafansonly2005]

The best supplement to spend your money on is a gym membership :)

[@Darcsheep]

And fresh, delicious water 💦

[@jcord0013]

Diet is #1. Then strength training and aerobics, in that order. You can't correct dietary deficiencies in the gym, unfortunately.

[@tamer6893]

@@jcord0013 Or Power training so you can hit strength and aerobics at the same time.

[@nimblegoat]

@@jcord0013 True, but for any normal person, not eating stupid. Strength and cardio better . Silly as both good. Gym can reverse diabetes and slow heart damage, make heart younger and immunity stronger . I think biggest difference for longer lived people is keeping moving, active , plus increases health span . I think easy changes in diet and more effort in exercise will give easiest gains. Ie 90% good diet 10% junk with exercise probably not too detrimental , especially for most of your life, given some people 80% crap , 20% good survive for quite awhile ok - which surprises me

[@melvillejayathissa7415]

Vigorous exercise!

[@saskhiker3935]

C15 is very expensive so I opted for Omega 7 sea Hawthorn oil. It is 3 times less the price and I can buy it at my local healthfood store.

[@fredsvlogandreviews5867]

I have been getting over whelmed with ads for fatty15 so I had to look into it. Thank you for making this video.

[@peggyr3288]

my fav doctor said worth trying ...

[@user-cg8if3eq7d]

We forget that everything works in a synergistic manner best. What were their diets, stress levels other meds and other health factors that could have effected levels?

[@DocSiders]

After 200mg C15:0 for 75 days my longstanding Elevated RDW values improved (nearly normal)... indicating increased Red Blood Cell longevity. Elevated RDW is Associated negatively with all cause mortality.... so very good results.

[@jet6110]

What is rdw?

[@ExtaTer]

If there is no other improvement, it is not worth the money. Better improve your diet. "Associations" in medicine is not causation.

[@Tom-w2f]

@@jet6110 A red cell distribution width (RDW) test is a type of blood test that indicates variations in the size of a person’s red blood cells. It can confirm an anemia diagnosis and help determine its cause.

[@jet6110]

@@Tom-w2f thanks for the explanation!

[@jet6110]

@@Tom-w2f have you taken this supplement?

[@ABeroud64]

Awesome work, Nic. Thank you. Love it when my intuition aligns with your analysis.

[@tedbear631]

Cool thanks for this. I've seen other videos of people hyping C15 and I wasn't sure what to make of it. Thanks for clearing the weeds

[@MoodEbony]

I was looking forward to this video, but this does not address the most prominent claims about C15. Reading the original papers leading from dolphins up to humans, the main mechanistic piece seemed to be related to improving metabolic health by reducing ferroptosis. There seems so be a strong link between ferroptosis and type II diabetes. As I understand, C15 converts to C17 in the body, which is then used heavily in the cell membranes, improving the selective permeability (emphasis on "selective") of the cell walls. Am I misunderstanding, and were there not some Scandinavian studies addressing this?

[@ExtaTer]

"Association link" in medicine is not causation but a foundation for pseudo science.

[@KelvindeWolfe]

This👆

[@ShannonHansenCook]

Absolutely I kept listening to hear the main point of c15 actually being addressed here, and frankly it isn't. Since people are all healing their own illnesses based on the amount of time their cell membranes need to repair/ turnover, simply correlating the c15 level to liver enzyme changes is not enough. A 40 year old with eczema, & inulin in their GI tract ( which c15 thrives on) may turnover all the connective tissue ( skin ) membranes faster than a sedentary 65 year old with arthritis ( bone ) who needs to heal. It's really not appropriate to discuss c15 levels and liver enzymes as if these values tell us with finality if c15 works which is what the title of this video implies- that it won't work based on these studies discussed. This video made me decide to purchase c15 and give it a try. In theory one could pulse c15 in a similar way as other anti aging drugs or supplements and get great results. This video didn't deter me, even though I wished when I initially clicked that it might, due to the price point. Assessment of data points that don't actually look at symptom relief from the diseases which c15 might help with over time, is rather meaningless.

[@jackiesmith-nq8in]

What exactly do they mean by Mediterranean diet? There are many different versions depending on who describing the diet.

[@whitewolf6730]

Thanks Nic! You are a real asset to so many people.

[@theBigEastBand]

As usual you make it make sense!

[@andreasrydstrom9112]

A thing that caught my eye was the study that in the title claimed C15 being a biomarker for dairy fat intake. I'm very sceptical of that idea since the data supporting that seems to be weak. I'm not saying that dairy fat doesn't effect the blood levels of C15, it surely does, but my point is that if you are going to use it as a biomarker it needs to be specific, there could be other nutrients effecting it as much or even more. The main suspect is fiber according to these studies: 1. "Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate", by. K Weitkunat et al. Am J Clin Nutr. 2017 Jun. 2. "Cross-sectional associations of food consumption with plasma fatty acid composition and estimated desaturase activities in Finnish children" by T Venäläinen et al. Lipids. 2014 May. I did the research on this 3 years ago, so there might be more studies on this now.

[@mistermiau9949]

dokładnie wow nie sądziłem że ktoś to jeszcze ogarnia o tłuszczach wiem wszystko znam wszystkie mechanizmy ich oddziaływania i garstka ludzi wie o co chodzi no i bez enzymów określonych to zmarnowana kasa tylko to co tworzy natura ma sens

[@6789uiop]

NOTE: The study cited @1:42 does not address heart issues as mentioned here, only diabetes; "Serum pentadecanoic acid (15:0), a short-term marker of dairy food intake, is inversely associated with incident type 2 diabetes and its underlying disorders." -pubmed

[@prole1917]

I'd be curious to see a study on C15 supplementation for those on vegan diets (given C15 is most naturally available in dairy sources)

[@cobraspyguy]

fiber along with gut bacteria will create C15

[@nikjovicic]

Lamb and sunflower seed have the same amount, butter (grass fed) and sunflower oil (high oleic) have the same amount. The difference in price is an order of magnitude. Also there is likely endogenic production so...

[@Star-uk1kh]

​@@nikjovicicDo you have any sources or further info re this please 🙏

[@nikjovicic]

@@Star-uk1kh Google scholar, search pentadecanoic acid, then go to scihub. You are welcome.

[@jamesellsworth9673]

I never went very far in chemistry or biology or statistics but I find I understand the general tendency of your instruction. It has value for me. Just now, I am trying Creatine and Taurine as an over-70 male. It is too soon to confirm positive results.

[@gazdacandrei2202]

I take Omega 3 suplements in the last 10 years, because my lacrimal film is not lipidic good and with omega 3 I manage to live without using eye drops for dry eyes. I bought fatty 15 to see if is any improve of lacrimal film. I took it for two months in parallel with omega 3 and I noticed a better energy during the day. In the second month I made sufficient enery to make some sport dayly. I feel younger and more potent in thinking and muscular. After those 2 months I ordered late a new package and I notice after 1-2 weeks more and more lack of energy and I was not tempted to to make exercise as usual. I was tired, like in the past. After received the package, only after two days my mood was improved. My lacrimal film is better with omega 3 and fatty 15 than simple omega 3. I don't know if fatty 15 will have the same results for others or not, but for me is great and I will order permanent.

[@cadthunkin]

Its good to hear objective information. People need to keep hearing "association is not causation", because certain personalities are so drawn to things they cannot explain, so they are, magic!

[@dpasek1]

I agree with your conclusion. I have seen a promotional video by a supplier pushing a $3 per capsule product which I think is absurd hype. It seems that there is *some* C15 SFA in dairy fat, and I am just going to continue with that source.

[@peterwillo5273]

My mail on c15 is that following low saturated fat diets for years leads to a c15 deficiency which causes a ferroptosis induced cell death resulting in metabolic disease and inflammation and supplementation in this case would be of great benefit . I’d be interested in your thoughts on this.

[@jaktao6044]

Your presentations are excellent sprinkled with a tad of interesting humor.

[@Gabriel-of-YouTube]

The more studies, the better!

[@loganwolv3393]

The more studies, the butter!

[@jmatt98]

I tried C15 for 90 days. I don’t see any difference. Don’t waste your money. The company talks about dolphin studies but no human studies.

[@epektasis242]

I'm a dolphin so I might give it a try. Thanks.

[@fannyalbi9040]

​@@epektasis242u r a rich dolphin nevertheless

[@fannyalbi9040]

not just dolphin but the so "clinical trials" r their own, similar to dr sinclair claims. hoax

[@terryhanson6033]

But did you try balancing a ball on your nose at the swimming pool?!!!

[@Dan-dg9pi]

Just out of curiosity, did you do before and after blood tests of the liver?

[@olyav5819]

Thank you for talking about C:15. I was not sure if I should buy it or not.

[@drgyt2469]

What exactly is a mediteranean diet?

[@wendyzakariasen7235]

Would eating those foods that promote C15 be just as good like grass fed butter and ghee?

[@OsAbliNgin911]

If you eat butter and not afraid of like the French, then you don't need C15 supplement because butter especially quality butter like grass fed butter is high in C15. Even Ghee is high in C15. There is a study called the French Paradox. Also there is a reason Ancel Keys left out countries in his study who eat a lot of saturated fat because it did not fit his narrative that saturated fat causes heart disease because those countries had a low rate of heart disease despite eating a diet high in saturated fat.

[@artsiecrafty4164]

Thank you. Butter is better!

[@2coryman]

Cheers cheers, thank you much, I take the stand of an open mind to possible future understanding or changes

[@adamp9553]

If it's essential, but lots of people already have it in their diet with dairy, beef, fish, etc., then an RTC needs a control group of people who've avoided those foods long enough- namely vegans.

[@andreasrydstrom9112]

Would have to be a fiber free Vegan diet in that case, since our bodies produce it from short chain fatty acids - the break down products from bacterial fermentation of fibers in our guts. But, when some are trying to push C15 as a supplement to the general public then I think it's appropriate to test it on people eating an average diet. Would be nice though if they would do proper dietary records to estimate the intake of C15 and fibers.

[@presence5426]

Fiber is murder.

[@richhahn2443]

Why assume that there is a sufficient amount of C15 in those products? The dolphin study showed that the amount of C15 in their food source had declined over the years.

[@edgarsnake2857]

Thanks for the no nonsense info.

[@kevingold1091]

As we've come to expect from you, great info, well presented. Thanks so much. If I might note, there seems to be an echo in your audio. MIght want to look into that.

[@mikecain6947]

another great video. Thank you.

[@Physionic]

Thanks MIke

[@abdeliribas6247]

Now i see why frensh poeple are often serving after dinner either some sweet desserts like creme brulee, or similar, or simply a cheese plate with different sorts of cheese. Did they already knows decades before, there´s molecule called C15 ? It is a plausibel answer ?

[@paulhindle3961]

Thanks Nick, very much appreciated.

[@not_sure...]

Ive been on a carnivore diet for a long time now and have healed many of my issues. I decided to give this a try since i saw what healthy fats did for my overall health and this did not disappoint. I thought i was getting enough of this from the grass fed/finished butter and goats cheese i ate but apparently not because this was quite the difference. I will say i do take more than the recommended dose so I think thats a reason why i see more of the effects it has on my body. Im gonna cycle off for a while after i finish this last refill though.

[@roqclimber]

Yes. Let's look at the First Study, First.

[@robertsmyk4102]

My understanding is that C-15 can reduce reduce ferroptosis (a condition that poisons the liver with excessive iron that is sourced from defective blood cells that the liver is programmed to harvest from circulating blood). These defective blood cells are produced when the metabolism consumed foods deficient in C-15. So you did not discuss ferroptosis.

[@AdilsonAdeodatoAzevedo]

Actually any saturated fat have the same effect as C15. What matters is the ratio of saturated to polyunsaturated fats in the cell membrane. And eliminating polyunsaturated fats from your diets is way more important than consuming C15

[@larsnystrom6698]

Thanks! Googling "ferroptosis C15" gave me a PubMed artikle to begin looking into that. "The Cellular Stability Hypothesis: Evidence of Ferroptosis and Accelerated Aging-Associated Diseases as Newly Identified Nutritional Pentadecanoic Acid (C15:0) Deficiency Syndrome" by Stephanie Venn-Watson Although, she's a Fatty15's co-founder, so maybe not the ideal info source for these things.

[@carinaekstrom1]

@@AdilsonAdeodatoAzevedo Eliminating polyunsaturated fats?

[@polycrystallinecandy]

@@AdilsonAdeodatoAzevedo Polyunsaturated fats are consistently linked to better health outcomes

[@AdilsonAdeodatoAzevedo]

@@carinaekstrom1 You should have no more than 2g of linoleic acid a day. Average american consumption is 10x that. Even If you try to eliminate it from your diet you will probably get more than 2g a day.

[@winstonallen6933]

Feeling much better about that mackerel ihad last night...thank you!

[@obsessedwithhealth]

I have had fantastic results with fatty15. Been taking for 8 months. 25 years of low back pain GONE, better sleep, better mood. I will take it for life. Never has any supplement worked as well as this one. I was very skeptical...now I am a believer.

[@peggyr3288]

the naysayers are always quick to dis

[@nobombs8784]

Obviously there involved in the sale or distribution maybe research 😂 I mean seriously just look at the person's name.. More scummy people that like to prey on the innocent naive uneducated to fill their pockets...

[@ExtaTer]

Thank you for grounding the hype about C15. It does seem anti-inflammatory from the first study sponsored by manufacturers. Notable from one of the cellular mitochondria studies was the U curve, i.e. C15 had diminished effect at concentrations higher than 20uM.

[@DonnaDCheney]

I have been taking Fatty 15 for several months now and I feel the difference. My weight has stabilized, my blood work lipids have improved and A1C level has improved. I am also impressed that a supplement company is actually doing clinical research on a supplement, using 3rd party research. I believe pharmaceutical companies freak out when OTC supplements are being researched as much as FATTY 15 is. I hope they continue to push and I hope they are successful. I will continue taking it. :)

[@6789uiop]

Sounds promotional.

[@ExtaTer]

You do know that your lipids and A1C can drastically improve only by stopping eating processed foods and sugars? No need to take overhyped and overpiced C15 supplements.

[@6789uiop]

​@@ExtaTer Too few ATP binding cassette sf g5 (g8) on enterocyte of gut wall, enterocyte. Or too many Niemann-Pick C1-Like 1 on the same gut lining, epithelial cell lining. Can make eating too much sat fat and cholesterol a serious problem, not just FH.

[@agauerm]

why you would "supplement" with C15 if you can just eat butter, beef and drink milk?

[@the_algorithm]

@@agauerm Hell even sunflower seeds / oil or Algea No need to spend $$$$ when Seaweed can be enough

[@susylove7739]

Thanks. You saved me money.

[@MichaelAmen316]

Thanks bro. Great work!

[@471444a]

Thank you for this education

[@cgillit]

Great analysis and content

[@mpvsystems9302]

I notice the p value for hemoglobin in the first study is also significant. This caught my eye since I am struggling to get my hemoglobin level up into the normal range of 135 to 170 g/L despite having a normal ferritin level and normal kidney function. Obviously there is insufficient evidence with only a single study at this time, but if this result can be substantiated in the future, it would offer another approach to increasing hemoglobin...

[@rileykonara]

Great analysis!

[@alternatedemon6060]

the fact that you were mentioned by vigorous steve is really something, your channel is growing and you earned it

[@keithrichard391]

Who is vig Steve.

[@AndyChananLevin]

Terrific

[@mballer]

Pentadecanoic acid, adding to my vocabulary.

[@jamesellsworth9673]

Too many syllables for me to get through.

[@LaidBackPedalPusher]

Thanks for your assessment. Looking forward to more about this. I have been chastised often about my love of butter lol, which I understand is the best food source. Looking for the connection.

[@carlr2837]

Butter should contain C15, but only if you buy butter from pasture raised cows. Kerry Gold is from pasture raised cows, and there may be other brands, but I haven't seen any.

[@1TieDye1]

Why do you understand it as the best food source?

[@carlr2837]

@@1TieDye1 Being that C15 is a fatty acid, it is going to be found in fats. So, if the cow eats grass, which makes the C15, the C15 is going to find it's way into fats, including butter and whole milk. It may also be found in fatty cuts of meat.

[@LaidBackPedalPusher]

@@1TieDye1 I saw it on a chart of values in a video recently. It was approximately double the amount of the next best source.

[@muleface1066]

It seems to me that a certain amount of odd-chain fatty acids occurs naturally in the food we tend to eat and that we've likely evolved to use that amount optimally. It would be interesting to me to identify a population that is 'deficient' in C15 or C17 (i.e. in the lowest 10 percentile) and document how their health might be affected.

[@mikafoxx2717]

Vegans/pescetarians? From what I hear they tend to live longer and healthier so idk about that.

[@Christopher-b1p]

Odd chain fatty acids are converted to even chain.

[@A91367]

I noticed improved sleep and less feelings of hunger between meals. Just my personal report/anecdote.

[@ExtaTer]

I felt hungry after dinner yesterday. I drank 2 cups of water (they call it the lazy diet) and the hunger went away. I also slept very well, despite eating a lot of sugar for dinner, which usually impairs my sleep. So drinking water works for me LOL

[@bttr9066]

@A91367 do you take it in the evening or morning?

[@A91367]

@ I take it in the morning. Not sure it matters though …

[@bttr9066]

@@A91367 Thanks

[@singerap]

Thanks for this.

[@dough5186]

Outstanding, incredibly-informative video. Thank you!

[@tomprovan50]

great info

[@samsungcb]

Question for you: why when I chew and mix with saliva some supplements the effect is stronger by comparison ingesting swallow them them? THis applies to fatty15 too - chew and mix with saliva effect is stronger compared with swallow

[@triciascribner6018]

I fell for this too...then I did further research..eat more real grass fed butter, it's in there, and other foods. Do your research...I tried the 90 day and cancelled, one tiny pill will not do much, then they said 1-2 pills a day, well not at this price!!!! If we just ate whole foods .ore often with good fats, it's a good start!!

[@OsAbliNgin911]

Hence why I think C15 supplement may appeal to folks on a low fat diet more because it is found in foods most people don't eat much of nowadays. The founder of C15 supplement claims we cannot get enough C15 in American diary because of the way diary is processed in the USA now. She basically made it seem like because of the way American foods are processed we are missing out of C15, so the only way to get adequate amount without the bad stuff is to buy C15.

[@triciascribner6018]

@@OsAbliNgin911 people need to eat more healthy fats, the brain needs it as well as other bodily functions! Grass fed butter is much cheaper than Fatty15

[@xanxus8272]

Thank you Nic. On a different topic, would it be beneficial for vegans to supplement with the meat-based bioactive compounds like creatine, taurine etc. (with or without exercise)?

[@earendil5884]

Great analysis

[@SW-nq1bx]

IF I read the second study correctly, it looks like C15 along with the Med diet, lowered Liver markers 4x as much as the Control group (that had nothing)? That appears very substantial.

[@Flexb777]

I tried C15 for over 9 months and I have found to do NOTHING of note. I have since cancelled the subscriptions and boy did they try to keep me hooked with lots of various price reductions but I resisted all.

[@hironakamura3466]

Hi Nic, thank you so much for your work! Is C15 really essential?

[@elinachiong]

Thank you for the indepth look. Maybe an alternative to Omega 3.

[@ccfd4813]

Nick- I love your channel, you are awesome- I have referred medical colleagues to your channel (I have dubbed a lot of what I watch on KZbin- “KZbin medical school”). Today your biceps are center stage. I had to go back and listen without looking 😊 maybe if you weren’t moving your arms/hands as you talk you could expose those guns!

[@timothytrudgen8881]

Why are you assessing it as a supplement? My understanding is it is deficiency that is a concern in the literature? Is that established?

[@MrBlaxjax]

I can’t see the point of buying fatty 15 unless you’re allergic to dairy. But I’m happy to in increase my consumption of dairy fat as that’s the easiest way to obtain c15 fatty acid. I’m interested in the circumstantial evidence that dairy fat might be really good for us. Basically westerners consume about a third of the dairy fat that we once did, and our metabolic health eg fatty liver disease has got worse and worse these last 40 years. And one study rather limply indicated improved liver health. There’s a bat’s squeak of possibility.

[@lorimckay2704]

So what industry put on this study and when I looked it up Rapseed oil has more C15 than Butter, but dairy and butter are all news seems to be promoting. How much C15 is needed?

[@mikafoxx2717]

This.

[@artsiecrafty4164]

Rapeseed is canola oil. No thanks, that stuff will kill you.

[@binathere2574]

Rapeseed/canola oil is not meant for human consumption.

[@binathere2574]

Rapeseed/canola oil is not meant for human consumption

[@monik8209]

What are the requirements to be able to understand your course? My background is not in science and I need to learn basics. What do you recommend?

[@maxhunter3574]

Are their any studies that show how much if any supplementing with inulin/chicory root powder increases c15 levels? Supposedly it does.

[@littlevoice_11]

Have you seen Dr Henry Chung at University of Essex has research showing genetic markers to predict which specific exercise will aid muscle gain, assist in weight loss and improve CV health? Essentially, he has found a genetic test to find which sport or type of physical activity will have the best effect for the individual. I understand Dr Chung was keen to share on some podcasts such as yours.

[@jonnull]

How about dat C60 buckminsterfullerene?

[@FXDUBOIS]

Once again, thanks a lot and big thumb up for the smart, valuable review... 👍👍👍

[@matthewm2223]

My problem with a lot of these things is we don't normally consume isolated nutrients, we eat foods. The c15 push included undermining natural sources for their even-chained FA levels. However, looking at recent human studies around the impact of consuming, partcularly, fermented dairy sorces (cheese, yoghurt, kefir etc) they point, if anything, to a net benefit for things like CVD risk. Authors have stressed the need for a better undersranding of the food matrix and how that, overall, impacts health. Indeed, the mentioned food sources will also have things like probiotics, vitamins, minerals etc and not just odd chain fatty acids but branched chain ones too - another promising class of FAs.

[@andreasrydstrom9112]

Very good job on the videos, Nic! Much appreciated, although I never was very hopefull about the C15 as a supplement. I'm more curious about the scientific basis behind the claims that dairy fats would be neutral/protective against chronic disease because of the C15 content and/or the milk fat globule membrane. But I understand that trying to answer that in a comprehensive way is a much bigger job, something like a whole phd degree.

[@toni4729]

I'd like to know when any saturated fat caused type 2 and heart disease? I've been soaking in it for my entire life and there's no way I'll ever suffer from either.

[@jingtroc23]

Id definitely try c15, but at that price... no. However, if i saw postive changes whilst taking it id be fine paying that price for it, IF i see/feel dramatic results

[@Fermentedbiome]

Do you have videos to reference or plan to make for understanding common mistakes seen applying the wrong statistical methods to certain datasets, and how to be aware of the common mistakes?

[@Physionic]

No, only my course

[@curiouskitten]

Fatty liver cause should be made public knowledge, not how to to use supplements to contain it. Just stop consumption of man made oils/fats and sweet drinks/processed Franken foods. That's what I did and it sure dropped the fat deposits in my liver. To boot, my c reactive protein inflammatory marker dropped from 3 to .29

[@MarkHK66]

CRP of 3 is better than 29

[@curiouskitten]

@@MarkHK66 it's 0.29

[@ExtaTer]

That is the TRUTH! But there will always be people that like to stuff themselves with junk food and believe they can take 0.2 grams of the "magical" C15 that will cancel the bad effects of their diet. Good luck to them!

[@johncaldwell9842]

Maybe I missed it, but I didn't hear you mention anything negative from the studies about C15, AKA butter.

[@mshannoncarver]

I started C15 3 months ago. It has made such a huge difference for me

[@Nobarkus]

If you want to get C15 naturally from food just eat Pecornio Romano cheese. It's sheep's milk cheese. You can get it raw (I read somewhere that they heat it at very low temps).

[@maranscandy9350]

What did the C15 dolphin studies indicate?

[@Laotzujm]

I like your analysis. It is my understanding that your body would incorporate C15 in the new cell membrane as your body is constantly making new cells. PUFAs in cell membranes can cause some cell leakage because of the structure of the fat, In order to understand this you would have to biopsy the tissue which is way more difficult than a blood test. Any thoughts on using it as part of cell structure and possible benefit?

[@RondaGoslawski]

Is there a difference between FattyC15 pantadecanoic acid and the Now brand or Pure Encapulations brand of pantadecanoic acid?

[@Physionic]

No

[@TowelReady]

They are both essential fatty acids, one isn't better than the other. Why are you comparing them? Both are required.

[@tinalouise9323]

Thank you for these videos and helping me get my medicine cabinet under control!! I was begining to think they were silencing you on the topic of C:15. ;) I was really hoping for a different outcome. 💔 The stages of grief have already begun. But before I cancel my subscription to Fatty.... (talk about marketing gueniuses! Only 1-3 claims addressed here.) They have MANY more claims including that C:15 is an ESSENTIAL fatty acid and a deficency leads to cell fragility syndrome. This PROPOSED nutritional C15:0 deficiency syndrome (termed “Cellular Fragility Syndrome”) is a form of accelerated cellular aging that MAY explain why aggressive forms of aging-associated diseases are increasing among younger people. Assuming we aren't eating a diet with saturated fat, do we still need this essential fatty acid to avoid cellular fragility?

[@ExtaTer]

The C15 claims have all the hallmarks of a supplement scam. They are all essential, decreasing with aging, and magical, so we have to spring the big bucks to get them LOL And of course no actual human studies to back it up, just "associations" and "linked to".

[@westcoastswingmusic]

I bought a 90 day supply, and am researching further to see if I should reorder. I still have unanswered questions about the red blood cells.

[@user-cg8if3eq7d]

The.hook and physical stance says alot about the content.

[@tamer6893]

There is already 1 g of C15 in cow Milk for 100 g of total fat. Diary products should be enough supplementation, and also included in the Mediteranean diet 😂

[@andrewb5004]

C15 supplements are a waste. Not getting enough in the diet could be a problem. Avoid low fat dairy products for this and other reasons. Aged high quality cheese is my source.

[@carlr2837]

Has anyone else who is taking C15 noticed a reduction in allergy symptoms? I read that many of the benefits of C15 are related to a form of C15 that metabolizes into pentadecanoylcarnitine, an endocannabinoid, so I recently added another supplement, carnitine, to see what would happen. I just realize that it is October, the time of year I usually have horrible seasonal allergy issues, and this year, I have none at all. Is it because of c15? Because of C15+carnitine? I am interested in hearing from others.

[@OsAbliNgin911]

That is expensive supplement to use for allergies. If you want help with allergy symptoms or seasonal allergies just buy raw local honey in your area, which is much cheaper. If you cannot get access to local honey in your city, then there is a company called Winter Park Honey out of Florida who sells a product called All USA Allergy Honey, which they have patented.

[@carlr2837]

@@OsAbliNgin911 I tried raw local honey. My allergies got better for a short time, then got much worse, and I ended up with the worst allergy season I have ever had. I haven't eaten any honey since then.

[@carlr2837]

My allergies did eventually show up, but later than usual. I can't say that C15 had any impact on them, after all.

[@alfredvincent13825]

Thanks for the podcast. You really do a great job, and your podcasts really cuts through all the IG type hype with all these supplement grifting companies. Btw, the white background and random painting are a little distracting , reminds me of a grandmothers spare bedroom in her Boca Raton condo.

[@CynCopeland-TheAnswerIsMeat]

... immediately screams 'pause the recording and level that print behind you please!'

[@DerekFrazier2014]

👏🏾👏🏾👏🏾👏🏾👏🏾❤ Thank you and my pockets thank you as well.