Can Low-Dose Naltrexone (LDN) Help Long-COVID?

[@zokioppmkd]

Im a doctor and a long hauler and LDN had helped me sooo much. Some days i feel better than before covid and i have more energy and motivation. I had a lot of neurological/psychological symptoms and ldn sorted them mostly

[@youngerlab]

Thanks for letting me know. That's great. A big question now is - how long should the LDN be taken once someone starts feeling better? It is possible the resetting of microglia would allow the medicaiton to be stopped. I guess I would do a taper, but there is no guiding info on that. Good luck! - Jarred Younger

[@DlcdrummerProSniper]

hello im 2 year long hauler and im trying LDN im on 1mg for a month about to jump to 1.5mg. What dosage helped your neurological symptoms? thank you

[@zokioppmkd]

@@DlcdrummerProSniper 3 mg and im not going further

[@SN2903]

How long did it take to help? I just started yesterday feel a little better today. Starting at 1.5 for a week.

[@rashidm65]

Hi Zoki, I have long Covid symptoms. Thank you very much for sharing your personal experience. May I ask you a couple of questions- 1. How long did you take the medicine? 2. Are you still continuing it? 3. Did you notice any relapse? Again, thank you very much.

[@lynetteprice8519]

Start with 1.5 or less. I had a 24 hour turn around. I noticed a huge change overnight

[@neemayaz1113]

I'm a compounding pharmacist that makes Low Dose Naltrexone for patients and it helps so many people with autoimmune or inflammatory conditions. Also is being researched with HIV, Cancer and a ton of other stuff. If it wasn't promising, you wouldn't see a bunch of people doing trials on clinicaltrials (yes pharma and research hospitals are getting involved). you can see it for yourself. LDN is the future and I'm proud to be part of its early stages.

[@kennethk9350]

can you mail some to me, i'm in canada

[@incensejunkie7516]

@@kennethk9350 you can get it compounded in Canada, I'm here as well and have been using it for about 4 years (ME/CFS and Fibro patient) I used Dr Younger's research and my dr was intrigued and prescribed it to me.

[@Followthechariot]

I had Chronic Idiopathic Urticaria, large hives that put me down for days and ending up in ER with blood pressure skyrocketed and fever. They were severe. They lasted around 7 years and would get them about once a week or less. Nothing worked to help it. Doctors couldn't figure out what was causing it. Hence Idiopathic. It did happen more often when I got around dogs as I'm severely allergic to them. I was on KZbin and there was a video on LDN. I never know what it was before that. I do have Autoimmune disease. I watched the video and it spoke about it helping people with autoimmune disease. I was able to get my old Dr. who was more like a functional med doctor to order me some from a compounding pharmacy. I couldn't believe it, as soon as I started it I never had hives again. It truly does help the immune system. It also helps with my Hashimoto's thyroid condition. Etc

[@banzobeans]

Good on you!

[@marinabattaglia5385]

I‘m a scientist and severely affected by LC. I will try anything with a reasonable safety profile even in the absence of large controlled double blind studies. On LDN since 4 months and it is really helping.

[@5000NATE]

What were your symptoms are they fatigue and just smiled weakness that's what I have weakness and fatigue at certain times

[@sharonmacdonald1765]

I got fairly mild dose of Covid 9 months ago. Then Long Covid which floored me. Breathlessness, cognitive issues, dizziness, nausea, erratic heart rate from 37 to 152: pretty wild stuff. Found a private clinic who prescribed LDN: it’s only been a month and at first I was downhearted thinking it wasn’t going to work. Miraculously after only upping the dose to 4.5 it has now kicked in. Wow, I’m so surprised and delighted to get my life back, The horrendous fatigue has gone as has the breathlessness, My bpm is still erratic but I’m hoping that and the dizziness will settle as time goes on. It’s incredible to have my life back. Ps I’ve continued to test positive for the last 9 months but now the line on the lateral flow is barely visible.

[@rubenkrieger3803]

Hey how are you now ?

[@lynetteprice8519]

Ldn gave me my life back. I'm about 95% capacity and went back to work. I'm also taking NAC and glycine is helping.

[@jimgill5706]

LDN and getting my vitamin D level up to around 100 ng/ml very quickly eliminated my brain fog, chronic fatigue, chronic depression, and many other health issues. I've taken it for over 10 years now. Great video. Thanks.

[@anymoose6685]

Thank you! My mom just woke up from long Covid with LDN. It was immediate. She has been stuck horribly sick for 3 years, in a barely awake state. I hope this is a cure for others too. I hope it works for me also.

[@anymoose6685]

Her Covid was so nearly fatal, incredibly severe.

[@AlexSelf-Help]

Any improvements?

[@wivinaclercent7433]

@@anymoose6685 9

[@melissahorn6091]

Did she have chronic body aches? I’m bed ridden after a virus due to body aches. Hoping LDN works, just started it today.

[@debra9040]

@@melissahorn6091how are you now? I just started ldn……hoping

[@زهرةالربيع-ل6ل]

Does LDN help with Functional Neurological disorder caused by Covid 19? My Symptoms are weakness of the arm with loss of movements ..would LDN help me regain movements?

[@katieclarkofpainfullyliving]

I take LDN for Fibromyalgia. After titrating up over a year, I am now (2.5 years) taking it two times a day at 4.5mg. I have not gotten COVID as far as I know (yes, I did get all the vaccines and boosters), but even more amazing is that this past couple of weeks our house got hit by a really bad cold; I was the only one in the family not to get it! (I know that LDN boosts the immune system, too. I secretly think I'm avoiding getting sick due to taking LDN. As far as my FM symptoms, LDN helps me have clear thinking, decent energy, and much less pain. What are your thoughts on LDN for those diagnosed with Fibromyalgia?

[@charlottepeters1683]

I got fybromyalgia due to Long Covid and my fybromyalgia has almost dissappeared after starting LDN, I still cannot believe how much it has helped me improve my LC in general and my fibromyalgia!

[@marshalevine7828]

I have been taking ldn for about 8 years. It hasn't cured me but, along with Sativex, it has reduced my symptoms considerably. It has never produced significant 13:18 side effects. Like Katie I have had all my covid vaccinations, though I missed out this year on my flu shot. Nevertheless I have not apparently had either covid nor flu since we'll before the pandemic. Maybe I've been lucky.

[@SN2903]

Hello. I'm a 11 month long hauler. I started on 1.5 mg 2 weeks ago noticed help with energy and concentration the next day. I went up to 3 after 8 days and didn't feel as good had return of lot of brain fog went bsck down to 1.5 and it is still helping.

[@Mansfield2375]

Hi, May I ask how you are doing on LDN 6 or so months later? Has your chronic fatigue been completely resolved?

[@monnmar1]

I had severe neurological issues post vax - pins and needles all over my body. I saw numerous drs and neurologists and for 12months no one offered me anything - I'm not even sure how I survived with prickling all over my face and body for so long - Finally i found a dr who would let me try LDN - it has helped already! Only been a few weeks - I'm wondering once you feel the symptoms have gone how many months following that resolution should people continue it to avoid symptoms returning

[@ttpearse]

Thank you for this video. I have been recovering from Long Covid for 3+ years. Blood tests indicate covid broke down my blood brain barrier, so I could see how my brain microglia cells could have been impacted. I also had some "black mold" in my system, which took advantage of my broken BBB to play havoc in my head. I had a large improvement the last 9 months after doing an 18 day water fast, which has healed my BBB barrier and now my ANA tests are negative (ANA tested positive for 2 years--before the fast). Just finished a 6 month mold detox protocol. Still have symptoms related to autonomic nervous system dysfunction and am looking at trying LDN--talking to my functional dr this week. Hopefully it can calm down my microglia cells.

[@911dips5]

2020 long hauler. LDN has taken away my inflammation, I'm so thankful for that

[@caseyg7945]

I m taking low dose naltrexone for brain fog with long covid. Its working for me.

[@kimberlyostertag9840]

I have fibromyalgia. COVID made it worse 😥

[@marieerrante-marron9089]

Have you considered trying LDN? There are reports stating LDN is good for those suffering with fibromyalgia.

[@SupremeODMG]

I'm going to be starting ldn soon for my palps, twitching, headaches and other weird nerve issues I'm hoping it will help with, I am Vax injured.

[@SupremeODMG]

Still haven't started but we'll be march..hope it helps i can't do this anymore longer.. I'm uploading some stuff soon 😪 soon my goodbye

[@enrichiing]

ive been taking ldn for my long covid cfs and pots now for 2 months and im currently on 2,5mg. after taking it my body heats up. has anyone made similar experiences or can anyone tell if this has any meaning or is just a side effect??

[@Hvitlys]

Yes, please do that 2nd video on specifics, will it be for ME/CFS patients too? I hope so (no Long COVID here, but infection origin as well). I would really appreciate if you can address how to go about dosing, since many of us are really sensitive to / don't tolerate meds. Finally I wonder what the real driver behind that neuroinflammation is, I hope it will be figured out at some point (reactivation of herpes viruses and other pathogens? Viral persistence in hidden places? Etc.). Thanks for the article link, btw, I've just skimmed through the text, it's free to access. Thank you!

[@Mau365PP]

I have long covid brain fog, I got a PET scan, and it showed hypometabolism on various areas of the brain. Is hypometabolism related to the microglia, and does LDN be a therapy option?

[@maurijnrezvani2743]

My brain fog was completely gone for a week with taking 0.5mg. Relapsed now and trying higher doses. Key for me was taking in the morning instead of evening, much better.

[@liliha986]

Have you found a dose that works again?

[@maurijnrezvani2743]

@@liliha986 I'm on 2.0 now but the amazing effects of the first weeks are not here anymore. Don't really know what to do. Maybe I'm just building up to 4.5 see if that does anything.

[@xer1000]

​@@maurijnrezvani2743 anything so far?

[@maurijnrezvani2743]

@@xer1000 I’m on 4.5 mg now and I definitely think it helps! I’d say I’m 80% recovered. On it for long covid.

[@nienkelovee]

@@maurijnrezvani2743 nice, do you think LDN was the reason for the partial recovery? Very happy for you!

[@cherylnielson5203]

Yes..please do the next video with more information! I’ve had this long Covid since March…8 months! Symptoms aren’t as bad as they were, but still bad enough I can’t do a lot, can’t drive, have horrible headaches and dizziness, fatigue, and brain fog. Mornings are worse. We need HELP!,! Next problem is getting this drug! I live in Bahrain…

[@mohamedeldeeb8895]

How are u now do u fell better ?

[@BoxVanDee]

You may not really have an answer to this, but will ldn help with PAROSMIA FROM COVID?

[@timmyschannel5]

I am taking LDN does appear to be helping me. My dreams however are surreal, but I've been told that will ease off. Starting on a very low does and working up to 4mg

[@SN2903]

What dose ? I started on 1.5 and it helps with energy and concentration some . Been 2 weeks

[@timmyschannel5]

@@SN2903 I'm on 2mg now. It has helped me like you, but I've a horrible pumping/throbbing sensation in my entire body when I lie down.

[@AlexSelf-Help]

Sexual side defects too?

[@PATHAN_writes19]

​@@timmyschannel5How are you feeling now ??

[@timmyschannel5]

@@PATHAN_writes19 I'm still shaking inside. Got diagnosed with focal epilepsy also. It's my entire vagus nerve , I can feel it

[@jimmyvincent123]

My Dr is willing to give it to me. He's starting me at a very low dose. 0.5 mg, and go up from there. For the first time I feel like there's hope! Fingers crossed...

[@TheIceyeddy]

Any luck Jimmy? My dr has given me a script for 0.5mg as well. Are you still taking 0.5?

[@angelikasusanne2830]

Does it help you?

[@KittenCasserole]

Thanks for sharing this important information. Since Long COVID started to emerge I’ve been wondering if this particular post-viral illness will provide the necessary funding and large trials to give us the necessary data we need to better understand LDN’s efficacy. Thanks for sharing your perspective. Many thanks to you and your entire lab for your tireless and vital work ❤

[@youngerlab]

I think it will help progress LDN research. It has been so hard to get LDN clinical trials funded, but it looks like that is changing now. - Jarred Younger

[@KittenCasserole]

@@youngerlab I’ve been following you for years, I’m aware of everything you’ve shared about how hard it is to get funding for clinical trials. This news is such a relief and gives me a lot of hope 🙏🏻

[@alisonreed4408]

I have seen several studies indicating neurological damage as part of Long Covid. When you say we have no evidence of neurological damage, what do you mean? Also if there is hypothetical damage, either neurological, endothelial or otherwise, that is causing microglial cells to behave the way they do in a response to some other process or mechanism that may be hypothetically taking place, would that pose any risk to the use of LDN and it's stimulation of microglial cells to return to their normal state?

[@Gil-zt8ur]

Question: do you think in the situation of having post-Covid mRNA vaccine syndrome it is also the microglia that has been adversely impacted?

[@ContraryMary]

Bless your heart. I'm an American living in Ireland and found the doctors here have to have numbers on tests that they can see before they believe a word the patients have said. I've had covid and long covid twice and spend most my days in bed. There's no way they would write a prescription. I'm visiting family in Colorado next month. Maybe I can get help there.

[@vickijohnson9367]

You have squalae. Any doctor worth anything understands post viral squalae. Find an Endocrinologist and/or Rheumatologist treating Fibromyalgia, ME/CFS with LDN. You should know this squalae is Spike/AC2 on going endothelial damage causing “coffee grounds” and large “Fibrinogen” clots, that can be treated with fibrinogenic enzymes, Lumbrokinase, Serrapeptase, Nattokinase. Do your research, supplements to support cellular activity including NT Factor Lipids and anti-oxidants, like Quercitin, Bromelain. There are many videos on here with the appropriate cellular and immune system support to properly regulate the dysregulated systems effected by squalae.

[@AprilLeighchronicallyme]

Yes it can!!!!!! I was on it already for my chronic fatigue syndrome and fibromyalgia and I had long Covid for a year! 5 months in my doctor added 5mg a day of prednisone and the LDN and prednisone together gave me a high push to get me out of long Covid and 7 months in I could see major improvements and at the year mark it was like the long Covid completely lifted off of me!

[@marxl19]

Can anyone help this poor lady?She hadn't been vaccinated before being infected with after covid19. On December 16, after covid19, she coughed and didn't have a fever. She kept saying that i couldn't sleep well when I coughed. On the 23rd, her eyes were swollen, her lips were blistered, dizzy, and confused. On the 24th, he started talking nonsense. She said she returning from another world, she will have antibodies if she bask in the sun, and she will be able to come back if she pat her face and rub her eyes with antibodies. NMR showed no abnormalities. Just had a lumbar puncture the day before yesterday, and the result was normal. During the period, the ct of both lungs changed from normal to lower right pneumonia and the cough became severe, and the nucleic acid test turned positive and then turned negative again. The onset was very urgent, and the patient did not have this tendency before. Now she basically lose her short-term memory, and she forget what she ate and did just now. It is difficult to fall asleep without sedatives at night, and she can only sleep for one or two hours in a row. When she don’t sleep, she lie down and cough all the time.Before the abnormality, she was troubled by insomnia. After the abnormality, she was very resistant and afraid of going to sleep. she said that she was afraid that I would not be able to find herself when she woke up. I thought it was caused by long-term insomnia, but fell asleep after being sedated for a week in the hospital，the sleep time becomes longer, sleep for four hours first, get up for a while and then sleep for a few hours, the mood becomes a little more stable, but the short-term memory does not improve and basically all is lost. In the morning, the mood and consciousness are relatively poor, and in the evening when the emotional consciousness is good, it is more persuasive. The doctor recommended her to take dexamethasone 6mg a day.I dont know if this is the right thing to do.sorry for my poor english.Is this long covid?It had been 21 day after she first infected with covid19.

[@tgsavel]

thanks for creating this video!!!

[@bradsalz4084]

I've been on 4.5mg/day LDN for 8 weeks and I still have my major long covid symptoms: head compression headaches, paresthesia, and tinnitus. I never had any brain fog or fatigue for which it is claimed to help, so maybe that's why. I'm going to continue out to 12 weeks as part of an open label study - it really needs a double blind placebo controlled RCT, of course - and see if there is any benefit. I do have more energy and don't seem to suffer post-exertional malaise (PEM) as I did earlier in the syndrome, but that wasn't my major issue. My experience is anectdotal. Maybe a different dose was needed? Multiple arms of an RCT in terms of doses and durations could help here.

[@garysippin]

I am suffering, serious neurological conditions, including tinnitus, and cold sensations in my feet, had Covid a year ago, doing anything to help with the tinnitus?

[@windowsofworthavenue5571]

Check your iron levels. Specifically ferritin. Standard CBC oy checks hemoglobin. You can have iron deficiency without anemia. Many if not all of those symptoms are present in low iron. Also if you are craving and eating ice 🧊 it's a tell tale sign of low iron.

[@windowsofworthavenue5571]

Oh and low iron can affect ears and tennitis.

[@AlexSelf-Help]

Sexual side effects too?

[@kwesidarkwa5443]

​@garysippin did you get any relief for the tunnitus.... mine feels like a brain inflammation with the noises at night just too much suffering...let's see what is helping you

[@liliha986]

Thank you for sharing your work 🙏🏻 This is so validating and explains why doing simple tasks take so much effort even though I don’t actually feel sick. I’ve had long-covid since Aug 2021, with brain fog that prevents me from being able to work and contribute to society. Saw your video and my doctor has prescribed LDN. I look forward to trying it & feel so hopeful. Has there been research done that shows a link between atmospheric pressure and how it affects the brain, especially if there is neuroinflammation? My brain fog is especially debilitating on days with heavy cloud cover & I wonder if there is science behind this.

[@7THxSIGN]

Doctor can it help with burning feet due to COVID-19 Long Haul?

[@Bo-zf2rj]

I use the LDN, but I move to Poland. How can I get it in EU?

[@jackbarhillel1065]

Fantastic and original doctor : as of April 2024 there still has been no DB-RCT for LD Naletrexone for long Covid, but there's "OVERWHELMING ANEGDODAL EVIDENCE" (in the words of Eric Topol, Nature 2022) for its efficacy which I confirm. People who have tried virtually everythig often come back to functional life with LDN - a little psychology or philosophy also helps... Basically the more time passes, the more the disease becomes, say, a functional trap... All the while, the sooner one has antiviral therapy (even after a few months), the better. I'm shock Paxlovid is so underprescribed. Had my retard general care pract. known, I'd have taken Paxlovid (3 boxes pease) I wouldn't be in that state. And PXLD would be more accessible, I'd do another cure right now. At 1000 euros a box, plus positive PCR needed, ... Totally prohibitive. ... Goverments don't seem to be giving a shit do they?

[@lennartjust727]

Thank you so much for this great and objective overview. As a Long COVID patient for 2.5 years now, I would really appreciate the second video you suggested.

[@BeeBop1029]

I would do LDN and I would also do eleostearic acid by mixing 20% pure tung oil, 80% safflower (for example), 2 drops am, 2 drops pm. I honestly think that would work very well. I’ve been doing oil for 5 years and LDN 18 months.

[@mattbellon828]

On 2 years with long covid, still short of breath, dizziness, dysautonomia type long covid. What is the recommended starting dose? Im hearing 0.5mg then go up to 1.5 morning and night. As most long hauler we have to tell our doctors what exactly to do that aren't too familiar with LND and wanted to see otheres experiences.

[@AlexSelf-Help]

Hello, can anyone report about LDN and impact on autoantibodies?? CFS/Long COVID sufferers often have excess AABs and this is assumed to block mitochondria from normal functioning. If some report better energy, I d guess AABs normalised? Anybody with blood checks and comparisons or any Informationen this? Thanks and bless you all!

[@dritonaliu5611]

22 month Long Hauler here. Still pretty bad cant really do 80% of what i used to pre covid. My biggiest issues are, head issues only way i can describe is a concussion/ feels like ive been hit over the head with a baseball bat. Another way i can describe it is if you spin around and then stop after the spinning stops the heavy head and pressure is what i feel. Its so debilitating ( my memory and thinking is fine). Also another symptom i have is this weak feeling i have( also with the weak feeling i still have strength i just feel weak so hard to explain). Also this wierd feeling in my body soo hard to explain. Just feels like my body cant relax. The wave of weakness and this combined is really bad. I also have tinnitus but that i dont care about. If i could get those symptoms down or resolve them that would give me my life back. I reached out to my doctor and he said no to LDN. He said he doesnt feel comfortable giving it to me. Its so hard to get anyone to help me.

[@FightingMECFS]

Do some researching, there are some facebook groups for LDN use - if you cant find one that specifies LC then look for MECFS or CFS and LDN Trust has a wealth of information and you can find more info on dosage and sources to get a prescription etc.

[@FightingMECFS]

(LDN trust has a website if you arent on facebook)

[@youngerlab]

I'm sorry to hear this. I hope if you can't get LDN, you can get a comprehensive set of tests to see if anything could be driving those symptoms. I can't give medical advice, but if the inflammatory panels were high (C-reactive protein or erythrocyte sedimentation rate), maybe the clincian will want to use some sort of anti-inflammatory. They will say those blood tests are too general (they are), but we don't have blood tests for brain inflammation - they require brian scans that aren't availabile outside of experimental lab MRI and PET scanners. I hope these symptoms resolve for you soon. - Jarred Younger

[@o.udolph8086]

I’m also a long hauler, what helped me was the FLCCC protocol (LDN is also included as a treatment option) They have a website with great info

[@dritonaliu5611]

@@o.udolph8086 Ive done all the Flccc protocol last year it didnt help. Also did Bruce Pattersons protocol for 5 months that didnt help ether and so many other protocols.

[@MrErick1160]

Hey, can I contact you? I have long covid neurologic symptoms since 3 years. Maybe we could have an exchange sometime? Would like to know your opinion.

[@brendanb3218]

really appreciate the work you are doing Dr. Younger!

[@AlexSelf-Help]

Thx for the video. I have now weak orgasms and low libido after taking 3 weeks LDN. I quit immediately but symptoms persisted since over 1,5 months now. I did not take ANYTHING else, and never ever experienced such symptoms before. My testo levels are through the roof, there is no erectile dysfunction, it's just the sexual sensations that blunted. Climax is no real pleasure (20%) and sexual desire not really there. I suspect it came from the opiate receptor blocking mechanism of LDN, which also makes sense, as the drug is used to get people off other pleasures like alcohol and shopping addiction. I was wondering what I can do to counteract these effects? Taking opiates to stimulate from the opposite side? Really concerned these symptoms stay persistent, like some sort of PSSD. Btw. another reason why I can clearly attribute these side effects to LDN, is that I am no longer tired after climax (0%), like I can come twice in 30min no problem, which seems fun, but not if you're not enjoying the act. It is known that LDN messes with prolactin, so just another piece of evidence, just don't wanna hear from anyone: it must be from other things. (I am 34 years young)

[@cautionwetfloor2779]

Can anyone explain why it may be that the paper on LDN and long covid (the OKelly paper) shows it to be pretty poor at alleviating most individual symptoms, in contrast to so many people's personal experiences? Maybe I'm reading it wrong?

[@5000NATE]

Thank you I'm going to get right on it I made an appointment with my GP but I'm really careful what kind of medications but my condition is a lot better due to my meditation and just being careful

[@atiqrahman6865]

hard to believe all this. but will use this on my patients and report shortly.

[@romygime5822]

Shame this drug is not approved in Australia. Is all the same thing we got to suffer

[@LoFoLi]

Hi Romy, I am on a LDN facebook group with 50,000 members and some of them are in Australia and they do get the LDN there. Maybe you could join that group and ask how to get it in Australia. Good luck!

[@romygime5822]

@@LoFoLi Thank you Dear friend Sorry I just saw the message. Thank you. I still sick with long covid. I just got the Naltrexone I going to try tonight before bed.

[@LoFoLi]

@@romygime5822 Good luck!!!

[@ognet]

So what was the outcome of your LDN trial and ME/CFS 7 years ago?

[@tx3md]

Thanks a ton for this video. Is LDN more effective if taken at night?

[@lynetteprice8519]

Take at night. It works by blocking endorphins temporarily, in order to get a rebounding effect with more endorphins. You're going to need endorphins during the day (trust me), so taking it during the day will have a counter effect

[@richard-et4ji]

So once you finish LDN do the symptoms come back? Is it therapeutic or does it slowly resolve the issue?

[@HanneFre]

Following

[@banzobeans]

Thank you for this!

[@vickijohnson9367]

Squalae is the description of post viral conditions (really not recognized properly). All all of these conditions are the same. All are squalae, with SARS having an added fibrinogen clotting long term effect that needs addressing, too Lumbrokinase, Serrapeptase and Nattokinase are enzymes to help break up on going coffee ground clots and larger fibrin clots that are endothelial spike protein/AC2 receptor generated. LDN *Good Endocrinologists Rheumatologists are helping, any physician with a serious mind and informed consciousness that is treating chronic conditions, since they have been front line for so long.

[@lynetteprice8519]

Could you post a good link on this so I could read further?

[@danray892]

I’ve had long covid since January. The brain fog and fatigue are debilitating. I want to try this! Let me know if you need a test subject! I live in California.

[@marvel_bro7598]

Same here

[@SN2903]

Same

[@marieerrante-marron9089]

You can likely get a script for LDN from AgelessRX

[@Nosey855]

@@marieerrante-marron9089 Yes, I got my script from AgelessRX. I started a week ago and my fatigue and brain fog have improved greatly! I can finally function throughout the day with no crashing or side effects. It's been a miracle for me.

[@PATHAN_writes19]

​@@Nosey855how are you feeling now?? Hope you feel better and live your normal life.

[@maurijnrezvani2743]

Thank you so much for this

[@taeah6672]

Very fascinating. I was just put on LDN for hEDS but I suspect all my problems circle around getting COVID (neurological "long COVID" symptoms). I'm curious how long folks were on LDN in correlation with long COVID before they came off of it and were considered normal or recovered. Honestly I am just hoping to get back to work soon, I hate having to go down when I am motivated to work and make money and just live my damn life. Thank god I managed to get financial support now so I can rest when I need to. Feel free to poke me in 1-3 months to ask if I feel any difference. Let's kick this virus in the butt and make a better world together!

[@taeah6672]

@prem shravan Unfortunately I got super dizzy and had double vision so I ended up having to stop all meds. No idea if it was the LDN or what but I am fairing okay now without anything.

[@taeah6672]

@prem shravan phew 50 is a lot, I was on 4mg before I stopped, we were aiming for 6

[@trederz977]

Hi Dr Younger, I'm looking at trying LDN for 3 months for chronic fatigue. Would that 4.5mg a day dose be your recommendation to start with? Thank you so much for all your hard work.

[@FightingMECFS]

You might want to take a look at the info on LDN Trust, they have a website and a facebook group. From personal experience most start out at a lower dosage and work up and you may find that, for example, you feel improvement at 3 but then not so much when you increase, that would indicate 3 is what works best for you vs continuing to increase but thats just from my personal experience and taking in a lot of other personal testimonies from those using LDN. The site i mentioned has studies and other information you might find helpful

[@trederz977]

@@FightingMECFS thanks heaps!

[@youngerlab]

This isn't personal medical advice - but it sounds like most typical is to start on 3.0mg/day and hold there for at least 2 weeks to make sure it is well-tolerated (some even start at 1.0mg/day before going to 3.0mg/day). Then can go to 4.5mg/day and hold there for 3 months to see if it works. I think it takes some experimentation to find the right dosage - but finding that right level - 1.0, 3.0, 4.5, 6.0, or 7.5mg seems to be a key in it working. - Jarred Younger

[@katieclarkofpainfullyliving]

@@youngerlab I started at 2.0mg and really had issues (dizzy, nausea, headache). I had to start at 0.25mg and titrate every couple of weeks. Even at 0.25mg that first week, I had amazing energy and clear thinking (which were some of the most debilitating issues I had with Fibromyalgia).

[@maurijnrezvani2743]

@@katieclarkofpainfullylivingI almost had the exact same! Especially taking in the morning helped me a lot.

[@jamiehowington3]

I’m on day 30 @4.5mg. Long Covid since January

[@kkds36]

Is it helping?

[@jamiehowington3]

@@kkds36 It's helping a lot of things. Now I am nearing a year. It hasn't knocked out my fatigue or 2 other nasty autoimmune diseases I am suffering from, but I LOVE IT and plan on staying on it for life due to the positive improvements so far. I have hope that it might knock out my bigger problems down the line.

[@carlajuhasz5697]

So my son has pots not from covid. Covid is causing pots neurological similar. Wondering if this could help with pots!

[@__OL__]

Is its ability to reduce microglial sensitivity born out of a different mechanism than the one responsible for its ability to increase endorphins?

[@johnathanabrams8434]

How does low dose naltrexone work for short covid

[@jessemendoza2991]

Do I need a prescription for LDN?

[@geminiflower]

Yes

[@lovewenwin]

Ageless pharmacy

[@bubsthirty5890]

would LDN be a good option for a person that is on Morphine?

[@damnninjas9375]

4.5mg LDN is a miracle

[@Kuriocity]

How about methotrexate ?

[@AlbAy537]

Thanks so much for this video. I have been dealing with long covid for 17 months. I am glad there is some information available here. A lot of doctors don't even know about long covid.

[@PATHAN_writes19]

Did you try LDN ? And how are you feeling now ?

[@VeganCheeseburger]

Thank you

[@AmpCee]

Thanks for your work!

Great info. Pls Pt. 2

[@maxnits9556]

Thank you for fighting for us, can't wait to see the updates! Cheers from a mecfs patient from Ukraine!

[@mariaserje1012]

Great video ❤

[@rdan721]

Hey Jarred, can you provide any updates on your study of dextro-naltrexone for microglial inhibition?

[@bradsalz4084]

I'm interested in this as well. Naltrexone has chirality, i.e. "handedness". The only version available is A-naltrexone. The issue is that A-naltrexone affects the opiod receptors which D-naltrexone does not. Because of this effect we are limited to very low doses of A-naltrexone - unless you are an opiod addict, where 30-50mg/day is used. D-naltrexone, as I understand, doesn't suffer this limitation and might be more effective because higher doses could be safely used. However, I cannot find any formal studies to support its use. I'm wondering if anyone has found information on this topic.

[@rdan721]

@@bradsalz4084 I'm guessing the lack of studies is related to the fact that pharmaceutical companies can't profit off it since it's been around for a while and can't be patented.

[@CarlSomers]

Thank you Dr. YOUNGER……….Best LDN video on KZbin in my opinion. After 4 x weeks, Handsdown Low Dose NAltrexone LDN (3mg, 1.5mg AM and 1.5mg PM) combined with CBD Oil (0.5ml per day) has been Life Changer for me with treating treatment resistant Long CV, Chronic Anxiety and Neural Inflammation. Most Local GPs and Specialist Doctors I’ve seen were not able to provide ANY Formal Long CV Diagnosis or suggested Treatments, despite suffering for 15 x months with the usual laundry list of PASC Chronic Symptoms…….LDN has given me back my Life in a major way. HBOT has been the only other thing to provide temporary relief…. 🙏🧠❤️‍🩹

[@cynthiastogden7000]

Forget long covid, I have suffered fibro. cos and lots more for many years. I have read about LDN but in the uk doctors will not prescribe it and you cannot get it anywhere else. So me and people like me are not given any chance of possible help.

[@nataliebutler]

You can get it in the UK and some GPs will prescribe it. Dickson Chemist in Glasgow fulfil the NHS prescriptions. You can also get a private prescription from them.