What is LDN (Low dose naltrexone) & Does it Actually Work?

Today we are going to talk about LDN or low dose naltrexone.
This medication is often prescribed to treat medications such as weight loss, autoimmune disease and chronic pain.
But does it actually work?
Will taking LDN actually help you lose weight?
Will it help you reduce your antibodies or improve your thyroid function?
Will it actually take away your pain?
I discuss all of these questions in this video and I talk about how often it works for my patients.
The good news is that LDN has few side effects, so even if it doesn't work it may be beneficial for certain people.
Download my free thyroid resources here (including hypothyroid symptoms checklist, the complete list of thyroid lab tests + optimal ranges, foods you should avoid if you have thyroid disease, and more): www.restartmed.com/start-here/
Recommended thyroid supplements to enhance thyroid function:
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- Supplements for those without a thyroid and for those after RAI: bit.ly/3tb36nZ
- Supplements for active hyperthyroidism: bit.ly/3t70yHo
See ALL of my specialized supplements including protein powders, thyroid supplements, and weight loss products here:
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Want more from my blog? I have more than 400+ well-researched blog posts on thyroid management, hormone balancing, weight loss, and more. See all blog posts here:
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Disclaimer:
Dr. Westin Childs received his Doctor of Osteopathic Medicine from Rocky Vista University College of Osteopathic medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Childs is no longer practicing medicine and does not hold an active medical license so he can focus on helping people through videos, blog posts, research, and supplement formulation. To read more about why he is no longer licensed please see this page: www.restartmed.com/what-happe...
This video is for general informational, educational, and entertainment purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Childs and you. You should not make any changes to your medications or health regimens without first consulting a physician. If you have any questions please consult with your current primary care provider. Restart Medical LLC and Dr. Westin Childs are not liable or responsible for any advice, course of treatment, diagnosis, or any other information, services, or product you obtain through this website or video.
#thyroid #hypothyroidism #hashimoto's

[@valeriet5581]

I've been on LDN for about 2 years and it's amazing. Not only do I feel normal again, but I haven't felt this good in decades. I take it for Hashimoto's and have zero side effects. My thryoid numbers have been normal since taking LDN, my joints don't hurt, I have energy, a positive outlook and now believe I will have a long healthy life. I've never had a weight issue, but now I seem to be able to eat whatever I want although I do tend to eat very healthy most of the time.

[@drwestinchilds]

Awesome! Thanks for sharing.

[@juliemcpherson9408]

Valerie Treese That’s wonderful! Can you tell me the dose you take? Also, did you start out at a lower dose?

[@valeriet5581]

@@juliemcpherson9408 I'm taking 4.5mg but started with half a pill for the first 7 or 10 days to lessen the chance of vivid dreams. I never had a vivid dream. A nice side effect is increased energy and I feel like I may be less I have a more positive outlook on life and situations in general.

[@chel103168]

Do you still need to take thyroid meds? I started armour this year and have more energy than I ever have had. I was on levothyroxine for 20 years. Thanks.

[@valeriet5581]

Michelle Bingham Yes, I’m still on Armour Thyroid.

[@hmgx2012]

12:32 starts talking about autoimmune disease

[@JanK0221]

I benefited from LDN, it truly was a life saver for me and I am on 1.5 mg.

[@janellek7312]

What do you take it for?

[@leeny777]

How long did it take for you to notice any benefits ?

[@organicfireorganicfire1236]

How high was ur TSH

[@hlsjones]

No, compounding is not the only way to get LDN. A 50mg tablet dissolved in 50 CCs of distilled water, Naltrexone is water soluble, and then taking the resulting liquid will yield 1mg per 1 cc of liquid. And doing it this way is way cheaper.

[@noriginal2546]

See? There are a lot of amazing doctors out there. Keep trying and listen to your doctor as long as they listen to you.

[@belindaw1970]

Cured me from Stage 3b N1 cancer in 4 months. Cannot recommend it enough! 4.5mg on pulse dosing.

[@adaleung6086]

Hi Belinda, you are taking LDN as part of a larger protocol or on LDN alone? Also, where are you getting the dosing schedule from? You are getting consultations somewhere?

[@macintosh4]

I’ve just started taking it. What is “pulse dosing”?

[@montanak7]

Every single person I know that used it for auto immune diseases has benefited.

[@cynthialewis2096]

Worth a try, as i don't think doctors have a clue.

[@montanak7]

@@cynthialewis2096 my 25-year-old daughter is using ldn for binge eating and diabetes and it’s working for her. I’m so happy.

[@debbiewalker2792]

It didn't help me. It made my CFS worse and I generally felt worse whilst taking it.

[@matthewj5555]

Been on it since 2005 for MS. No relapses, no pain either.

[@twitch451]

What dosage do you take?

[@matthewj5555]

David Secore 3.0 now

[@vishalakshikishorreddy7207]

MS Means what health issues you have Will it work for footdrop

[@Anni_12349]

Great 👍

[@angeminc]

Did it help with burning pain and itching?

[@smiller8688]

I have Lyme and use LDN for pain and it works for me!

[@brendabrenner2891]

Have same. What dise +where did u get ittu❤❤

[@LoewinSarah]

Thank you for the great video! How bad is it when you have to skip taking LDN for two days? My pharmacist was out of it and i can only get it again in two days. Have been taking it for 3 months now and i love it!!!

[@lucylu530]

It is worth saying that it can take a long time before you see the difference. It took me six months and then, boom! It worked. I think it was working all along but I had three Autoimmune diseases so there was a lot of healing to be done.

[@lucylu530]

I take it in the morning now. I feel fine.

[@windyxfairy]

Julie_ Knight_ take it in the morning 👌🏼

[@browneyedgirlFL67]

What dose are you on?

[@NurseKGrant]

This is an excellent video!! I love the analogy with a blood pressure medication that reduces blood pressure by only 1 mm/Hg. It's a simple, but great point. As providers, it's easy for us to oversee things like this - we focus a lot on the potential harm and are sometimes blinded to the potential benefits of a drug. Thanks for the video. - Kyle Ellis, DO

[@drwestinchilds]

Glad you found it helpful! Thanks for stopping by.

[@MsAmalinka]

@@drwestinchilds Hello! I'm from Ukraine, and I'm doctor, pathologist, so it's Hard to believe, but I 'm suffering from SM, so I could eat whatever to decrease my symptoms, is LDN helpful for me? Thank You for Your answer

[@drwestinchilds]

@@MsAmalinka I'm not 100% sure if LDN helps in SM, but it may be worth a trial.

[@JM-co6rf]

My heart rate is finally normal because of LDN.

[@heatherbates789]

Viagra is the most famous use of off label in history. Originally a blood pressure med and voila 😅 This was a great video!

[@michellerenee8887]

I'm on 50mg a day to help with weightloss a few months before bariatric surgery. Works great! I also have degenerative disc disease and chronic lower back pain. I don't take it for that but since I've started months ago, I barely have ANY pain!

[@officetechtyping]

How is going now? I too am on 50.

[@michellerenee8887]

@@officetechtyping it's going great! Right now, I'm down 34 pounds since I start the program in February. I actually meet my surgeon in 2 weeks to schedule the surgery. It's finally gonna happen! How are you doing on the 50mg?

[@IlIKRATOSIlI]

Thats not LDN by the way. LDN is considered sub 5mg

[@yodaddy9362]

I got prescribed 50mg too. I took 1 dose and it was absolutely terrible. I had ringing of the ears, I felt paranoid, blood pressure was through the roof, super nervous. My throat was on fire. Then I read the long term effects and I threw them in the trash. Ig it wasn't for me.

[@sentidocomun3460]

saben si se puede combinar con inmunosupresores ? gracias

[@lindagarcia8826]

Great information thank you so much.

[@prettiep]

The way you speak is so easy to understsnd, thank you for sharing your knowledge and experience with us! Have you any information on how people with CFS/ME can benefit from LDN?

[@drwestinchilds]

I don't have any info on that particular topic but I can add it to the list of future videos!

[@prettiep]

@@drwestinchilds thank you!

[@shawnaford5540]

I will soon be starting LDN for ME/CFS. If you look up Mayo Clinic Proceedings Oct 2023, there is a really good article. “Diagnosis Management of ME/CFS. I shared it with my physician and LDN is one of the management considerations.

[@diannemarinari7936]

Hi Dr. Childs. I'm 69 years old with type 2 diabetes and was diagnosed with PMR in June by a Rheumatologist. She prescribed prednisone saying there was no other treatment available. and that I may have to be on it for one to two years. I started out on 15 mg, and the specialist reduced it 4 weeks ago to 10 mg. Slowly, I have been experiencing pain in all the same places as before, although it's manageable for me right now. The pain I was in from the PMR back in June was excruciating, and I don't want to go there ever again. I've been very concerned with my high blood sugar levels and informed my PC about them. She said "they are going to run sporadic as long as I'm on prednisone ." It makes me feel she just chooses to "look the other way" instead of looking into alternatives. I feel lucky to have found this video today and hope LDN may be an alternative for me, because I"m so fearful of the damage prednisone is doing to me.

[@PandaA-cv3mm]

You must definitely try LDN.

[@patriciakirby5575]

You should it has the least amount of side effects and pred caused me to become borderline diabetic...join one of the LDN groups with the Problem you have you will learn a lot ..be informed

[@jettcosta9735]

Same here! Only answer Prednisone! Sure it’s awesome but how long can you be on it? I start LDN today! I’m so excited 🎉

[@PebbleBeachLife]

After a few days of taking LDN I can say for sure that my appetite is diminishing. I would possibly call it an absolute cure for binge eating disorder. I only take 1mg daily sprayed directly on the tongue. The larger dose, 50mg did not work for me, I was constipated and gained weight. I was taking painkillers by the handful daily and now find myself not wanting it at all. LDN for the win!

[@djquick]

50mg is not LDN! Why did you even try that high of a dose?

[@PebbleBeachLife]

@djquick I was given wrong instructions by my GP. I had to do my own research to figure it out.

[@meme1star]

I've been on LDN since last July for Hashimotos. Its definitely helped lower my antibodies along with helped get rid of inflammation I was dealing with and I did loose 10lbs more toward the beginning of taking it. It's not a significant amount of weight but it's the first 10lbs I've been able to keep off in years. I sleep sound except for the nights that I have vivid dreams, that is one of the side effects but even thats few and far between for me. I'm one of the patients who doesn't want to give it up..ever. It's not a miracle cure all drug but it definitely has helped along with the NDT medication I take. One more thing I know that's happened since taking it, it brought up or reactivated the shingles virus twice in me..the first time was pretty significant, the second time was much less and I haven't had anymore reactions for about 4 months so hopefully that's over. I've talked to other people that have had the same thing happen or other viruses that it has reactivated but same as me they were less and less severe each time and then it stopped. Thanks for the video. I always look forward to them.

[@lisaa6099]

meme1star di

[@jeng.1439]

What dose do you take?

[@ArtsDigitals]

@@elizabethblackwell6242 Hahaha...That's hilarious!!! The subconscious mind has its own agenda, apparently.

[@PandaA-cv3mm]

This is exactly what I am experiencing right now. I have had several viruses found in my lumbar puncture which they believe could have triggered my autoimmune issues. The side effects are horrendous at the moment. Like a very bad flu, but they have told me to keep taking it. So I am desperately trying to stick it out.

[@paul2019monte]

@@PandaA-cv3mm How is it now? Curious if it will reactivate/make worse EpsteinBarr?

[@qualitydag1]

I read that using LDN for CFS is pretty effective. It has been reported that its 73% effective for chronic fatigue patients.

[@susant8134]

I have Hashimoto's and wanted to try LDN to help resolve pain and other issues. I have read where some patient even have lowered their antibodies after taking LDN, so they lowered their thyroid meds. My Dr. Immediately said no. He didn't think there was enough studies to indicate LDN would help. I'm going to attempt to talk to him again about it when I go next week for an appointment. I know some Dr.s won't prescribe if they think the treatment is anecdotal. I hope I can convince him that it wouldn't hurt for me to try. I'm so tired of being sick. He ups my medicine and I'll be good for about a week, then here comes all the wonderful symptoms rushing back that inevitably lands me in the bed. It's quite depressing. Thank you for this informative video.

[@2017_K___Booth]

I get my prescription from a doctor I learned about on KZbin. Her name is Dr Handler, which may be her channel name. I see her on something similar to Zoom and she orders my prescription and it ships to my home.

[@2017_K___Booth]

This is how I get mine.. kzbin.infoXdvStDNzg7E?si=m7ti6-tN9deAgGo7

[@elliott3991]

I am a Rheumo/Fibro patient. been on 3mg for exactly a month. 6 days ago I had more energy than I have had in over a decade , or only on my very best days back then. Still have more energy . May not be knocking down the numerous pains that still surface despite lyrica, anti depressant, and naproxen. Hopefully maybe some more improvement in the next six weeks. But biggest change I have had in a decade with a shelves full of prescription drugs.

[@romanadam206]

Hello ! If I’m on buprenorphine patch 70mcg/h for pain, do you think I can start LDN without stopping my pain medication?

[@cindy6903]

Contemplating taking LDN for longevity I have no health issues I'm turning 60 and trying to stay on the cutting edge I do also take blood pressure pills.

[@marcusduff2124]

Is it safe to do LDN in conjunction with the LDA therapy I'm currently doing or would that be counterproductive?

[@Shayne_T]

I'm not sure why I even care if I feel well .. but I have to be very strict about it.

[@montanak7]

My doc wouldn’t write it. Another doctor did but wrote it incorrectly. Didn’t write it for compounding rather but 50 mg one a day. So I take 50 mL of distilled water and I crushed up the 50 mg pill and I dissolve it in the water and keep it refrigerated. And then I draw the medicine off the top with a syringe and leave the coating/bideers in the bottom. And then I can does 1 to 1. 1 mL 1 mg. Easy Peezy.

[@jean6460]

How do you know it’s the medication on the top?

[@montanak7]

@@jean6460 it’s way more water soluble than the coating and some of the binders. What I see at the bottom is visibly coating. Don’t need that.

[@patriciakirby5575]

I brought this to my Rheumatologist after 9 years of drugs that made me so sick it was worse than the autoimmune dx itself and we were out of options so we had nothing to lose.....I am happy to say I am finally in remission by with lots of damage ..as an engineer I would say use as first line drug as it least side effects..and if it works for you then you can eliminate the damage of autoimmune....because of the asshat Rheumys I had prior I significant damage to joints to vestibular system(balance) and significantly ruined my life as I knew it.

[@patriciakirby5575]

Now in remission on LDN for 4 years....wish I didn't have to fight for a diagnosis and effective safe treatment....and the weight loss is easier after years of pred adding 150 LBS to my body

[@gabid3653]

@@patriciakirby5575 what autoimmune disease did you have?

[@patriciakirby5575]

@@gabid3653 relapsing polychrondritis

[@kseniyaalive3772]

How long did it take to get you in remission?

[@patriciakirby5575]

@@kseniyaalive3772 officially 1 year but the number started going down within months ..in remission 8 years on LDN

[@rep4666]

dr can this be used with methotrexate,,one supports and one suppresses the immune system,,thx

[@Vbswedishfish90]

Has anyone you know experienced any variance in libido while taking LDN? Seems like someone’s genetic profile might have a correlation to the insomnia side effect vs others not experiencing the same effect. Thanks for the video!

[@IlIKRATOSIlI]

I think the insomnia side effect is correlated to dosage and time of day its taken.

[@annbarber2571]

I had been talking LDN for about three months with some positive effects. I got Covid and the positive effects diminished to the point i couldn’t tolerate same dose and had to reduce the dose. Any thoughts to why it stopped helping?

[@JRock1900]

Can it be taken with Mestinon? Issue: Myasthenia Gravis

[@srfnow]

I am taking LDN for Spasmodic Dysphonia. People think this is a “neurological” voice disorder. However I truly think the root has something to do with the hpa axis, T3 and low body temp. I am really hoping it will help bring my voice back as I am a professional singer and I cannot seem to find a doctor to help me go this route. I know a lady who has he same diagnosis and her voice completely returned when her temp regulated.

[@alexwoodhull5130]

WOW, I so hope this works for you 🙏

[@winxclubstellamusa]

That’s fascinating! Did it work?

[@MoonChylde0622]

Dr. Childs, thank you for sharing your knowledge! I have a question I hope you may be able to answer: Since LDN blocks the opiate receptors, can it not be taken in conjunction with Kratom? (Kratom is a natural herb that gives opiate-like pain relief by reacting upon the same receptors as opiates, but lacks the harmful side effects) I'm wondering if the LDN would render the kratom useless. Or can they be taken at different times without the kratom being affected?

[@michaelsteven1090]

No, do not use it with kratom or any opiates!..I'm a former 5 yr kratom user and finally quit 3 months ago..It is a nightmare over time and quitting is very hard..Your brain is storing endorphins while using naltrexone, so stimulating more with kratom or opiates would be too much once the opioid receptors free up..

[@musicguy20]

Jenni McGary Any update? I just found this info and use Pregabalin and Kratom to survive to fibromyalgia.

[@shenghoulee9181]

Dr child’s, you did not discuss the prokinetic effect of LDN for SIBO . SIBO can be due to autoantibodies after infectious gastroenteritis, will it help ? Thx

[@drwestinchilds]

It's possible that it can help but I don't find it as good as other prokinetics.

[@shenghoulee9181]

Thank you Dr child, so what prokinetic do u recommend? Thx

[@terifish3321]

It works

[@joannepaul1976]

I have LPP, arthritis in my hands and feet. Do you think LDN would be worth trying. Don't take meds, but losing hair, inflammation on scalp very discouraging. Thanks. What dosage would you recommend.

[@barbarajane527]

1.5mg dose. Share your experience!

[@deborahakey9308]

I take 3 mg. Daily Wonderful ❤

[@fancynancy2134]

Can someone with AFIB use LDN? And what about people who are diabetic and taking insulin?

[@user-vf7jm6rh1p]

Do you have to take it with Thyroid meds? I have hyperthyroidism and heard LDN might make it worse because it regulates your thyroid

[@missyhilary8905]

I have been a migraine sufferer for fifteen years. I’m totally blind, which has nothing to do with it, but I finally got fifty milligrams of ketamine infused on Thursday. My doctor doesn’t have the space to do four day treatments for me. My question is, that I’m also on 4.5 milligrams of LDN. Should I stop the LDN, since I’m getting such a small dose of ketamine? Will the LDN block what the ketamine is trying to do? Because I got a pretty bad migraine today, and the only thing I did differently was to take my LDN the night before. I really want my life back. I uesed to cook, bake, write music, play instruments, and sing. I want all that back.

[@drwestinchilds]

I believe ketamine works through a different mechanism but I am not 100% sure off the top of my head.

[@Shayne_T]

I'm curious.. what's the difference between LDN and cytomel?seems like they have some things in common. . Can you take t3 and ldn together?

[@drwestinchilds]

Cytomel is a thyroid medication and LDN is an opiate antagonist.

[@Shayne_T]

@@drwestinchilds I understand, but both cause weight loss and better mood. Some stop taking their thyroid medication all together..

[@lisamariesanchez80]

I’m taking both . Just started yesterday.. I love dr.westin Childs .. your info is much appreciated.. ( Hashimotos,PCOS,hypothyroidism 🙋🏻‍♀️ . I stopped taking synthroid addressed it to my new dr. About the ( gluten, soy & fillers it contained that has caused Eczema ) since I have stopped synthroid my red patches an hives an red dots have subsided . Thank you Dr Childs for all this info.. which I would have found you 5yrs ago. It’s been quite a struggle an I really appreciate my new Dr. That also practices the same way you do .. can’t wait to see what a month from now will be an feel like

[@mi3bys049]

What are your thoughts on Oxytrex? I had just titrated up to the 4.5 mg dose of Naltrexone and had surgery (pin in my foot). I was prescribed Oxycodone 5 mg tabs. I have to say that for me, the Oxycodone lasted longer in my system. I was recently diagnosed with Hashimoto’s and my body does not absorb medications like a normal person. My dr. (who is a MD that practices mainly naturopathic medicine) told me my body only absorbs about 30% of any drug. When I looked up Oxytrex it is so new that it was in Phase 3 of clinical trials in 2017. I liked the fact that I didn’t feel ‘high’ on the oxy/naltrexone yet it took the pain away and for a longer period of time! I also didn’t have to titrate off of the oxycodone. I had no side effects from stoping the oxycodone.

[@Shawn2526]

I thought you are not supposed to take narcotics when taking Naltrexone

[@claudiodominguez.]

I thought that taking Naltrexone while on opioids will put you in precipitated withdrawals ? You should elaborate a bit more and edit your post, someone will be in a world of hurt if they do this. I hope that you are healthy and happy, nutrition is a big factor in holistic health.

[@calviv1]

Only way I can get it is through contrave ?? Is that ok for ldn?can I cut the pill in half?

[@montanak7]

As a chronic pain patient for 15 years. I have to disagree ...narcotics absolutely do help. They gave me enough pain relief to participate in life with my children. I do not go to a pain clinic to get them I just do without. But now my children do without me as now they don’t have a mother that has medication that works long enough for me to show up to an event or a performance or anything.

[@faithf5846]

So sorry to hear 🙏. We all need different meds or supplements or foods to help us get through. No one deserves to be in pain. I hope you get the help you need ❤️

[@fawkes1570health]

Hi Dr. Childs, Do you happen to know if the effectiveness of ldn is improved with optimal vitamin D3 levels?

[@drwestinchilds]

Not that I've seen, but I haven't necessarily looked for a connection.

[@drwestinchilds]

I do not! But, I will look into it.

[@fawkes1570health]

Dr. Westin Childs Thank you!

[@fawkes1570health]

I've also heard that getting facial breakouts (pimples) are an indication that the dosage is too high. I'm currently on 4.5mg. What's your take?

[@drwestinchilds]

I've used it hundreds of times and have never seen that side effect. I've also used various doses ranging from 1 to 50mg in these patients. It's still certainly possible that it could happen, I've just never seen it.

[@melanierichardson3063]

I was recently put on LDN. In the last two years I've lost 63 pounds unintentionally and started having horrible gut pain. I'm down to 100 lbs. I read where LDN was for weight loss. I need to gàin , not lose. I've had several test done and nothing turns up in labs or an upper/lower GI. I have multiple health problems, one being Hashimotos. I take 3mg at night and this is my second month. Should I be taking this in your opinion?

[@phoenixrising9352]

Melanie Richardson Possibly that you are taking too much, that’s a pretty high dose

[@susant8134]

Since your weight loss began 2 yrs ago, we can rule out the LDN for the cause. There are many things that can be a contributing factor. Even though your gi scans came out normal, I would suggest good probiotics. My gi's were fine, but I had terrible pain and bloating. I also juiced veggies that were good for tummy troubles. It did work. I'm going to assume your gallbladder was looked at, as well. Best wishes.

[@djmisey]

Have you also been checked for Type 1 Diabetes? It does not matter your age T1D can strike at any time & can cause weight loss & stomach pain. My 26 year old niece got down to 89lbs over 1.5 years & was finally diagnosed with T1D after thinking it was a number of other things. She’s thriving today now that she’s on insulin thank goodness & has regained 35 lbs.

[@SharonBrown-sv6te]

Can this help me ...I do Thyroidectmy ?

[@PebbleBeachLife]

I actually tried 50mg Naltrexone for food/opiate addiction but it caused severe constipation, I actually gained 7kg so I stopped it. I still have a few tablets left, so I've mixed one tablet with 50ml water and taking one spray on the tongue daily. I'll come back and give an update after a few days, no idea what to expect.

[@paulharrisonadventuregearm5457]

Dude....50 mg isnt the dose you use for LDN....that is only for getting off opioids

[@yodaddy9362]

@@paulharrisonadventuregearm5457 and alcohol. It was the worst experience ever. I just did it on my own it was that bad. Atleast I had terrible experience with it

[@wtpwtp]

Any update on your experience diluting a 50 mg tablet? Are you using a syringe to measure out 1mg doses (or another low dase amount)?

[@VTKARI1995]

My dr prescribed full dose for post glp maintenance. If the does is NOT low dose, will it not help?

[@donnadrastata7349]

How often and how well does it work for anxiety? That's what my doctor prescribed it for. It's really my only symptom but nothing else has worked. If it does work for anxiety, at what dose and for how long? I am only up to 1.5 right now

[@browneyedgirlFL67]

@Donna Drastata how are you doing on the LDN? Did it help with your anxiety? What dose did you see a difference?

[@rommajiwan1972]

Did it help with your anxiety?

[@snahg2356]

@@rommajiwan1972it is helping my hubby with his anxiety

[@qualitydag1]

I read that LDN helps up to 74% of CFS patients that hav tried it.

[@mary158100]

LDN gave me terrible brain fog, somtimes lasting for almost the whole day and suddenly it lifted like in an instance. I still have brainfog now that I am off LDN but not as bad. Also my mood was low and I felt very stange and tired all through the day. I have Hashimoto's and hoped to lower my antibodies. LDN helped to get rid of all the pain I had in my arm and shoulder. At first I had less appetite, but then I got hungry all the time. For the first week my sleep was disturbed and had I had strange dreams. I stopped LDN for now, once again, but will give it another go soon.

[@lucylu530]

I wonder if your dose was too high. Done people need as little as. 05. I'm on 4.5mg. It's been a life saver.

[@patriciakirby5575]

It tooks 3 weeks of the worst flu like symptoms of taking it but I had through extensive research that might happen and one morning I woke up w/o pain and started dance with joy....and for 6 years I am in remission with my numbers so much better.

[@ellam1434]

Use a smaller dose

[@sheronlyn2693]

Hashimotos people should only be on 0.05mls daily. Anyone with any thyroid disease should start at 0.5mls and stay there for months or longer or forever and have ongoing blood tests to check antibodies and thyroid status as things can change fast and thyroid medications will need to be adjusted accordingly. I am hypothyroid(diagnosed in 1993 at age 42) with low levels of antibodies but never told I was actually a Hashimotos patient until recently. I went onto LDN 0.05ml liquid and within 2 weeks had to decrease my eltroxin medication as my T4 levels had risen past high normal range. I havent checked my antibodies as yet. I also went onto LDN for lower back pain and leg pain due to injuries from 2 falls and also for constant sensitivities/allergic reactions to foods which drove me crazy as Im already gluten, grain and dairy free. The pain problems and food sensitivities also noticeably lessened quickly even on that ultra low dose which I will be staying on for as long as it keeps working. Its so important to have good advice, be monitored closely and keep to the right level for you as we are all different and metabolize at different rates.

[@JanK0221]

@@ellam1434 I am on 1.5 mg, I have Sjogrens, and my immune numbers went down. I feel much better, no pain, no brain fog, yes vivid dreams, I am much improved since a year of being on it.

[@lisafabrizio9811]

Hi, I'm a 41-year-old mom just starting to take LDN for weight loss. I have an increase in anxiety. Is this normal?

[@sheronlyn2693]

Lisa Fabeizio Ive done alot of research on LDN and people who have anxiety etc were told to go down to 0.5mg daily and build it up very slowly over a longer period of time and find the level that suits you.

[@lisafabrizio9811]

@@sheronlyn2693 thank you for getting back to me. Anxiety hasn't gotten worse but its still there .

[@ottoavila9895]

Ldn is also used on cancer

[@mysterioushands69]

i took 4.5mg had nasty side effects i think it was too much for inflammation

[@josestracke5317]

I'm a little confused about what dosage to take and if you are supposed to reduce the dosage after a few weeks. Can anyone help?

[@lucylu530]

You should start low and increase slowly. If you don't feel well after the increase and you should stay at the dose where you feel well.

[@andrewnelson1684]

Dosage: start at 0.5 and increase by 1.0 every two weeks with a max of 4.5mg. evaluate at each step of the way and see how you feel because a lower dose of 2 or 3 might be optimal for you

[@neilmcmanus3727]

Dr. Bernard Bihari was a pioneer in the use of LDN, here is an excellent video of an interview with him as he answered many questions and tells the story of how he came to use LDN in patients and he and his wife. KZbin Title: "Dr. Bihari is interviewed about Low Dose Naltrexone LDN for Normalizing Immune System Function" 06/27/2014 1Hr19Min, I found this very interesting, Dr. Bihari mentions T helper cells upregulated, he describes the dosage range at minute 43 in the video. Dr. Bernard Bihari (1931-2010).

[@nadinesokie9]

do I take it with food or wait on empty stomach thank you

[@drwestinchilds]

Either can work.

[@brendabrenner2891]

Does thus dr do telemed to get ldn...lyme + long covid❤

[@angeminc]

Anyone use this for burning nerve pain and itching- If so please share result, and dosage.

[@LoriGreco]

I have just started for small fibre neuropathy and believe it works! Started instantly but stopped after 3 days. I started at .5mg for one week then went up by .5mg until I found the right dose for me. So now I am on 2 mg and think I will settle there. Good luck!

[@susanferguson4271]

Now, it is 6 years later, any updates?

[@lesg5260]

Would it help for gout?

[@marcelaseven979]

I consult if LDN can reduce a recta tumor of 15 cm or exist another formula, thanks a lot

[@PebbleBeachLife]

Doc, can I share this video on my Facebook page?

[@titapetiotas]

U r not supossed to ask that, just post it🤦🏻‍♀️. The credits are his anyway

[@pouranszekely_kiraly4764]

My doctor got mad at me when i asked for it 😔

[@rachelfenicle280]

Many people helped from Dysautonomia

[@laurie9522]

How Do you get it ?

[@rachelfenicle280]

lau rie compounding pharmacy.

[@rachelfenicle280]

lau rie Skips Pharmacy in FL

[@jessicawalker5313]

That’s what I’m taking it for. I’m on month 2 and hoping to see some positive results .

[@chel103168]

Hello. My 24 yr old son has a desmoid fibromatosis tumor that is squeezing the main nerve in his arm. He has been in severe pain for 4 years. No opiates helped the pain so he started using medical marijuana wax. His tolerance is now so high he is not getting any relief. Could this help him? His new oncologist started him on Gleevac March 10,2019. I asked his Dr about this and he said its just for people addicted to opiates so it wouldn't help my son. I don't know where to turn to help him. Thank you for your help.

[@gravityworks777]

Michelle Bingham, look up Drs who prescribe LDN in your area and see them.

[@andraconstantin9459]

4.5 mg gives me vertigo and dizziness - still after sticking it out for several weeks.

[@MK-sx3pf]

Does anyone have weight gain while taking this medication and what might be the mechanism. Calories the same

[@XFullMetalX32]

I have asked 3 doctors about trying this medicine and all three knew nothing about it and refused to prescribe it for me. I have Hashimoto's, fibromyalgia, psoriatic arthritis.

[@JonasAnandaKristiansson]

I feel you, DON'T give up on this one. In Sweden it ain't easy to get anything that is truly helpful, anything that is healing and good for humanity, like LDN. The best to you!

[@missyblanks9916]

Have you been able to get on LDN yet? If not hoping Facebook LDN support group where you find you can get it without “your” doctors prescription.

[@gusseroni2575]

Miracle drug.

[@leegauss1782]

Maybe in many cases people do not receive the benefits because the dosages needs to be adjusted or their diet has foods that disrupt it been said you have to be gluten free, and dairy and meat. I think it also said one should stop those foods for while and if you eat dairy or meat it needs to be grass fed no grain fed animal.

[@drwestinchilds]

Dose is certainly one reason why it may not work for some people.

[@rommajiwan1972]

Can it help burning mouth syndrome?

[@gailducrest8851]

Can I continue taking Tramadol while trying out LDL?

[@drwestinchilds]

Some people are able to take low dose narcotics and LDN, it depends on your dose of tramadol and LDN.

[@Sherbear71481]

My doctor and pharmacist refuse to go any lower than 4 mg people are scaring me with the no way you need to slowly titrate so now it's just sitting in my drawer and I'm afraid to take it! 😢

[@drwestinchilds]

LDN is generally very well tolerated compared to other medications out there.

[@helgabruin2261]

Try taking half of it

[@lucylu530]

@@helgabruin2261 even 1/4 at first and see how you feel.

[@patriciakirby5575]

the damage from AI is far worse than LDN

[@belindaw1970]

I started on 4.5mg and am acutely allergic and highly sensitive to most medications. Not a single side effect was experienced with the dosage and my cancer was gone in 4 months.

[@Marfilla]

I've been taking 2.0mg for over a year and I don't get sick as often anymore, sinus inflammation gone, more energy, my digestion stopped acting up. About fibromyalgia pains, I still have them, and my Hashimoto's antibodies are still the same. I will try to increase to 3.0mg soon and see if it works better. But for sure I won't stop taking it. Now I am ordering from UK since I moved to Portugal and here they don't have it.

[@rosemerikosteki5232]

Hi Marlene, where do you get it in the UK?

[@drsnah]

hi, I am an MD in Portugal and you can get it now.Martins pharmacy in Lisbon in Calçada de Estrela

[@Marfilla]

@@drsnah thank you for your answer. I actually found dr. Sergio Figini in Portimao who is prescribing it in liquid form Naltrexone at a cost of €4 and also went to the public clinic in Silves and a doctor was willing to prescribe it too. 🥰

[@Marfilla]

@@rosemerikosteki5232 Dickson Chemist

[@stephanieolsen8148]

What about LDN and Phentermine?

[@drwestinchilds]

They can work well if used correctly.

[@tessap5280]

it can reinfect TB damn I had a form of that as a child the doctors said that's what caused me to have this growth under my chin when I was 2 years old I did want to try it for inflammation but now idk I also have graves and had a TT 2 years ago so wanted to try it for insulin resistance and insomnia bummer the TB I had wasn't the contagious form I'm not even sure because like I said I was only 2 and my mom doesn't know what med they had me on for a whole year before that they stuck me with these super long needles I can still remember it and my brother to this day still has a fear of needles So anyway they ended up cutting it out and left me with a sad looking scar thanks for this video you mentioned making a after TT one I'm excited to see it !!

[@annawilk7399]

Tessa Padgett?k

[@tessap5280]

Anna Wilk are you confused

[@Daisy-on1bz]

Tessa Padgett no it can’t reinfect TB. He was referring to some alpha inhibitor drug. LDN absolutely doesn’t do that ha.

[@tessap5280]

Daisy 2081 okay

[@tessap5280]

Daisy 2081 hahaha

[@nessawithsmiles]

Can you take LDN with NDT?

[@monicachappell6285]

Yes

[@Rinzist23]

Anyone used it for Burning Mouth syndrome?

[@joannfreedman1625]

I took 1.5 mg for a week and it made me feel awful, weak, tired I could not even move, I have Hashimoto's chronic fatigue fibromyalgia, also generative disc disease. I would like to try it again in the future starting off on a lower dise like .5 mg and then work up but my insurance does not paid for it and it cost $40 you have to increase the dose every couple of weeks I will revisit it a little later. I had no problem sleeping but when I stop taking it I had very bad acid reflux and I was very hungry actually what I was taking it I did not crave caffeine but again I think my appetite was increased especially when I went off it so I could have possibly some insulin resistance Maybe?

[@tellitallnow3914]

I purchased LDN from online, 50mg tabs. I take the tabs, break them in half and it makes 2- 25mg halves. I then take 25ml distilled water and drop 1/2 (25mg) of a pill into the water and let dissolve. Then I take a small 5 ml syringe and 1ml equals 1mg. 1.5mil equals 1.5mg,, and .5ml equals .5mg. I purchased 30- 50mg tabs for $100. Do the math on how many doses you will get out of 1-50mg pill then multiply by 30.... . I had no insurance so I had do what I had to do. I am sure there are others in this predicament.. Not giving anyone advise, this is just what I had to do.

[@mi3bys049]

@Tellitallnow My dr had me do the same with Vyvanse because of the cost. She gave me 70 mg capsule and I dissolved in water and would adjust until I found my dosing instead of several prescriptions with varying doses

[@sheronlyn2693]

If you did the proper indepth research on LDN it says hashimotos and fibro, ME, chronic fatigue and other conditions need to start at 0.5mg and build up over a longer period like even 4 months or as long as it takes. Anyone having negative reactions needs to do this. We all have different metabolisms and body chemistry so you find what is the right level for you by starting at 0.5mg and build up slowly. Alot of people never need anymore than 2.5mg to get results. Likewise if you are on a lower dose and notice improvements but after awhile feel some return of the old problems then upping the dose usually works. Ive also read in my research people who have low vitamin D, which is a given with autoimmune diseases, dont get as good results as dont people who are gluten sensitive and eating gluten. Get your Vit D levels checked by a blood test and supplement if needed and stop eating gluten and all grains which you shouldnt be eating anyway with aut0immune diseases as they cause chronic inflammation resulting in your autoimmune diseases in the first place. You need to reduce your over active immune load by dropping these foods so your inflammation in your body reduces which will help your body heal. Check,out Dr Peter Osborne head of Gluten Free Society USA, Dr Tom O'Bryan world renowned Functional doctor and educator of medical professionals and people like us round the world who want to help ourselves who want to understand what causes autoimmune diseases and how to recover from them and put them into remission, also LDNscience.org which is a great site to learn all about LDN. Plus LDNresearch.com. Nobody should be treating themselves with LDN without medical guidance and certainly not buying it online and dividing doses etc. That is so dangerous as these online sellers can be bogus and mix anything into these drugs and not compound them properly causing uneven results. There are plenty of warnings about doing this if you read the appropriate sites with doctors and specialists who work with LDN. Of course doing everything right doesnt guarantee good results because not everyone does but doing it right has to be the better way to go. Goodkuck.

[@athenalorente1610]

Start with .5mg. I started with .5 and increased to 1mg but I wanted to reach 4.5mg faster so I increased the dose to 2mg. Bad idea! dizziness, and vivid dreams/nightmares all night. I just go up .5mg at a time now and get no side effects. I'm at 3.5mg now and I have to get mine compounded because I have sensitivities, allergies to medication and also have IBS. The higher the dose the higher the price, a 45 day supply for 3.5mg it's $125 :( But Im hoping to reach the magic number soo.

[@Gypsy_Soul7]

Athena Lorente Good information, thanks!! 👍🏻😊

[@madelinebartorillo9823]

Is it safe to take while breastfeeding?

[@drwestinchilds]

Generally, doctors recommend that you avoid it during pregnancy/breastfeeding, but there are some people who have used it without issue.

[@madelinebartorillo9823]

@@drwestinchilds thank you! My new md wanted to start me on it for crohns and uc but I tandem feed 2 kids so I'm extra careful.

[@raloufen4292]

Years ago.. mu h more data.. cancwr Dysautonomia ect

[@angela1981]

Anyone benefit from it for Sjogren's?

[@margueritemcnair9402]

Yes watch drbeen he interviewed people with MG and have no more problems.

[@The_New_Abnormal_World_Order]

So if it binds to opioid receptors it is a type of opiate drug right???? It also blocks natural opoids... doesn't sound healthy to me.

[@marioluciooliveira9985]

It is not opioid, it is a opiod antagonist

[@melissajohnson8050]

I am so tired of medications not working for me. I've been on LDN for 2.5 months. While it has given me my first painless period, since I started taking my appetite has increased and my cravings are stronger. Mind you I've been sugar free for 10 years and gluten/grain free for several years. When I say cravings, I mean like cheese or yogurt (triple zero) or fruit etc nothing like junk food, but I want to eat more and feel like I have less will power. Still exhausted since I started taking thyroid meds. No energy, sleep is the same. Why can't I feel better?

[@drwestinchilds]

As far as I can tell, each person is a huge puzzle and it takes a lot of time and expertise to figure out what you need.

[@Shayne_T]

I have been in your situation. It's been a long process for me to figure out what would work for me, lots of research. I am now taking liothyronine (generic for cytomel)..but my dose can change day to day, depending on what I eat, how much I eat.. or how long I fast after dinner.. I now eat OMAD and same exact time, my medication works.

[@Shayne_T]

I also eat beef.. 100% grass fed.. and that's it. I started adding heart/liver, I'll have to see how it goes..

[@PandaA-cv3mm]

I just started it and am having terrible side effects like dizziness, swelling, sweating and chills. I imagine that it’s like a herxheimer reaction as I have had several viruses that have effected my immune system and presumably resulted in a few autoimmune diseases. Anyone else have really bad side effects when starting out? I know it’s an immune modulator . I’m a pretty tough trooper but this is really rough. Feels like flu and more. Thanks in advanced.

[@AndreaPerry3]

I started about a month ago and am having that. Are you still taking it? Did your side-effects go away? (I know your comment was a year ago)

[@PandaA-cv3mm]

@@AndreaPerry3 I had to stop taking it, unfortunately. I have not returned to it. It’s so odd as I heard such wonderful things but perhaps the physician did not dose me properly. For me it seemed to stimulate my autoimmune issues. I did get a pretty bad relapse of my Epstein Barr virus (mononucleosis). I am sorry that you are going through this. I hope it goes better for you. 🙏☺️

[@AndreaPerry3]

I’ve heard that some people get worse for about 2 months before they get better, but it is challenging to stick it out when it makes you feel even worse than the awfulness that made you start taking it in the first place. How long did you stick it out? Also I’ve heard of people who took as long as 18 months to experience the benefits!!

[@faithf5846]

Try taking a small tiny amount. I have been on LDN for years on and off. Right now it is helping along with getting my Ferritin level up My back facet syndrome has been in remission for a few weeks. I’m hopeful. I only take 1 to a half mil. Of LDN If I take more then 1 mil it can make me nervous and jittery Go s l o w Best to you

[@alisamassey]

My doctor uo the side just a little bit and I had horrible side effects ! Pain in various places, brain fog, dizziness. Once I quit the dreams lasted for days

[@rubennm.vieira4634]

You say for skin "tratnoan" ??? English is not my first linguage. Try google and nothing. Can someone write for me what is that and whow is write to i find more information ? THanks

[@thecraftyappletreedebmack3759]

Rubenn M.Vieira the word is tretinoin

[@drwestinchilds]

Yes, tretinoin is a topical retinoid that treats acne and reduces wrinkles in the skin. I personally believe it's better to get it from over the counter face creams (like from Obagi) than from the pharmacy. The pharmacy loads it with several fillers and binders which can cause skin issues and irritation.

[@rubennm.vieira4634]

@@thecraftyappletreedebmack3759 thanks

[@rubennm.vieira4634]

@@drwestinchilds thanks. already find out now the information

[@libraryfiles4470]

Modulates Cortisol?

[@kimlebaron]

Library Files does that mean it increases cortisol?

[@libraryfiles4470]

I read that it does but only a little though everyone may vary. I was thinking that if cortisol was raised do to pain and naltrexone lowered pain, perhaps it will lower cortisol in some. Ashwagandha lowers cortisol.

[@kimlebaron]

Library Files I have high cortisol plus hypothyroidism.. I’m about to start LDN and I’m just a little scared.. I do suffer from anxiety due to the high cortisol and I just didn’t want to make it worse.. what’s your experience with LDN?

[@libraryfiles4470]

Kim LeBraon I don’t notice any side effects from naltrexone. What is your cause of high cortisol? What are you taking to lower cortisol?

[@kimlebaron]

Library Files not sure why I have high cortisol.. I do have hypothyroidism and I know adrenals are affected along with thyroid.. I’m taking supplements to lower cortisol like Seriphos and ashwagandha..

[@johngalyen2315]

I take it for a rare skin condition

[@noornaser08]

john galyen does it work?

[@johngalyen2315]

Noor Naser well right now I’m dealing with a bad infection so it’s been really hard right now but it was getting better before I got an infection

[@saraann3468]

If you don’t mind me asking, what was your skin condition? I suffer pain and inflammation in my skin and I am really considering LDN

[@becca1364]

Has anyone used this for adrenal fatigue ?

[@drwestinchilds]

Naltrexone? I have never used it for that specific or isolated purpose.

[@montanak7]

I went through 4 chemos and a biological. Three of which I was allergic to. In addition it reactivated my Epstein-Barr virus and I have been sicker than I have ever been. And it didn’t do anything for my autoimmune diseases but back them multiple.

[@jamicampbell2374]

I was thinking of taking before I heard it can cause weight loss. I'm already underweight....I need every bit of fat I have

[@phoenixrising9352]

Jami campbell Yeah me too

[@phoenixrising9352]

Ugh... loss of appetite and weight loss??? Im already extremely underweight and eat very little

[@antonbende8210]

F ** YES - NO weight loss