CAR T cell therapy for cancer treatment: How it works

Chimeric antigen receptor T cell therapy - often called CAR T cell therapy - is a type of cancer treatment used to treat children and young adults with acute lymphoblastic leukemia and adults with large B-cell non-Hodgkin lymphoma. With this type of immunotherapy, T cells are extracted from the patient and modified in a laboratory to express the chimeric antigen receptor, which allows the cells to better recognize and fight cancer. The modified cells are then expanded to large numbers and returned the patient through an IV to begin attacking the cancer.
Watch Dr. William Wierda discuss how CAR T cell therapy works as well as side effects caused by this cancer treatment.
Learn more about CAR T cell therapy, including who’s a good candidate for this therapy and the latest clinical trials: www.mdanderson.org/publicatio....
Request an appointment at MD Anderson by calling 1-877-632-6789 or by completing our online self-referral form: my.mdanderson.org/RequestAppo...

[@tomjenkins8817]

Had CAR T treatment on 9/25/21 for large B cell follicular lymphoma and just finished a PT scan on 10/23 with good results. Had my treatment at Penn cancer center in Philadelphia.

[@mdanderson]

We're glad to hear you're doing well, Tom. Best wishes to you.

[@nathanrumpf5660]

Great explanation. Thank you!

[@chayweb3523]

Research as ever before such advancement are pivotal to medical breakthroughs and saving lives.

[@killshotdank7450]

This is incredible

[@cchiliman]

Very informative, thank you!

[@jeansharman8466]

Very interesting will continue reading Later. Tonight Thank you 😊

[@sayrilmahayawanshi2209]

It is an great info on threapy...Thanks.

[@isaacrayo2375]

Thanks for the explicación, very clear!

[@JohnEliopoulos]

amazing

[@naveenantony7849]

Does anyone know which type of T-cell is used in its own modification in gene editing/therapy dor cancer treatment..is it Th-Cell or Tc-cell..?

[@robw69]

How exactly is a T cell modified? What is the process of modifying a T cell?

[@revisionfour]

Would this work for Lyme disease?

[@JarredChaisson]

Wow nice

[@jeff6429]

This Video is more than 3 years already and what progress has been made since? Appreciate if more follow up information/video on this please?

[@mdanderson]

Hi Jeff, researchers are continuing to improve the benefits of CAR T cell therapy. You can learn more here: www.mdanderson.org/cancerwise/what-s-new-with-car-t-cell-therapy.h00-159464790.html. Best wishes to you.

[@theHerathrig]

Hope we find a way to get this to work with solid tumors. End all lung, pancreas and colon cancer.

[@jeansharman8466]

Amazing

[@lonexmo1605]

What about peripheral T cell lymphoma??? I mean T cell is in the name so I’m guessing this could help that.

[@user-vs3gg8nb5g]

Can T-cells used in asthmatic patients or in those who having pneumonia several times

[@user-vs3gg8nb5g]

Must try this research it may succeed

[@godesscoin5143]

Thank you sir!💩

[@soro911]

I wonder how much that treatment could cost? $$$

[@mdanderson]

Hello, you can see price transparency information for our treatments here: www.mdanderson.org/patients-family/becoming-our-patient/planning-for-care/insurance-billing-financial-support/health-care-disclosures.html. Best wishes to you.

[@tonyp2632]

How effective has the treatment been and are side effects permanent (muscle aches, confusion, seizures)? Are there any true success story's?

[@Shouq.a.m.d]

tony p read about Emily whitehead, she is a girl with relapsed refractory ALL successfully treated with CAR T cell

[@lesleydickson7746]

I watched a documentary about this in the U.K. Some people have been in remission for over 2 years.

[@ShyAnn291]

My mom had this and about a week after the cells were put back in she became unresponsive and was that way for about a month before she died. I’m sure there are good stories though.

[@MatthewSears_11]

Would this work with brain tumors?

[@Adriatiklota]

🙏🏻

[@Jin-ww7jn]

can we just modify t cell factory in my body? it's too expensive for regular people to take this treatment. take out t cell from body and modify and duplicate and inject. it's too expensive.

[@emmanuelking9988]

I'm reading that a prolonged water only fast (21 days at least) can reboot your entire immune system and healthy cells start eating away at damaged cells 🤷🤷

[@chayweb3523]

Research as ever before such advancement are pivotal to medical breakthroughs and saving lives.