Cholesterol Synthesis Regulation

This video is about rate determining step in cholesterol synthesis. Cholesterol biosynthesis rate limiting step or cholesterol synthesis regulated step is catalyzed by an enzyme HMG CoA reductase. HMG COA reductase converts HMG COA to mevalonate by using NADPH. HMG COA reductase is regulated allosterically, covalent modification, regulated the gene level by SREBP and SCAP, and by insulin and glucagon.
In this video I have explained in detail how cholesterol synthesis or cholesterol biosynthesis is going on in the cytoplasm of our cells. Cholesterol is synthesized by the condensation of acetyl CoA molecules eventually forming 27 carbon cholesterol molecule. While explaining cholesterol synthesis I have also explained different uses of farnesylpyrophosphate into dolichol, ubiquinol (CoQ10), and prenylation process.
Video link for cholesterol biosynthesis
• Cholesterol Biosynthesis
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[@MatirManush-wu9cc]

Thank you Prof. Dr. Mungli for explaining this complex process in possible simplest manner. It is a great pleasure to learn biochemical processes from your video.

[@DrMungli]

You are most welcome. I try my best to keep it simple.

[@greenyoga5790]

Wow! This was really clear, concise and helpful! Thank you so much!

[@natashamohdsupi]

Thank you for delivering it in the most understandable way. This is really helpfull! :)

[@DrMungli]

You are most welcome..

[@filmiindian01]

Hey please tell me is biochemistry difficult?? I just passed 12 class.... And want to know did I pursue bsc in biochemistry or not??

[@shivukgowda9651]

Ty so much sir plz keep making these kinds of videos its very useful to students....

[@DrMungli]

most welcome, yes I will

[@shivukgowda9651]

Sir I have one dought how arachidonic acid metabolised in cox pathway sir plz make video on this sir

[@GEO-rm4wp]

Hey I was waiting for this video doc Thank u Doc can u please tell me a Medicine against worms inside stomach?

[@DrMungli]

You are most welcome.

[@anikaitkaushal6910]

such a simple explanation sir....thanku so much sir🙏

[@doctorofmedicine1113]

no.need to open book....it helped me a lot

[@DrMungli]

I'm happy that this video has helped you.

[@thusanangunity6454]

I so wish Sir you continued further from the mevalonate until cholesterol ☺️...

[@satwikpradhan3559]

nice explained sir

[@DrMungli]

Thank you

[@BioMedKitwithBanik420]

sir...very nice and concept clearing... #Dr.Mungli .....will you make separate video on SREBP protein??? Plz...

[@DrMungli]

Will try

[@tariquenaseem674]

Sir in mevalonate 1 carbon is less by mistake I think plz respond

[@manishat7432]

Hello sir. ..thank u for lectures...plz let us know about molecular biochemistry i.e, RNA types,protein synthesis and DNA replication..find it too difficult to absorb these concepts sir...thank you sir...

[@DrMungli]

Though I currently do not teach molecular biology but I will try to make videos on the topics requested in coming days.

[@manishat7432]

Thank you so much sir...

[@hawinetzewdu]

thank u sir

[@DrMungli]

Welcome🙏

[@ikraa.2600]

Thank you so much!!!

[@gaurvigarg2899]

Sir pls share genetics videos.. thankyou

[@DrMungli]

I will try.

[@harshagarhwal7266]

Hlo sir upload some video regarding linking number

[@698-preshitagarwal3]

Sir it should be NADP instead of NAD In the rxn

[@filmiindian01]

Hey please tell me is biochemistry difficult?? I just passed 12 class.... And want to know did I pursue bsc in biochemistry or not??

[@meghaagrawal9723]

Aapp Kamal ho sir 🙏

[@Anonymous-007]

Megha Agrawal i love u shona

[@meghaagrawal9723]

@ I love you too jaaaan😘

[@DrMungli]

Thank you. I'm glad this video has been helpful to you.

[@sophiedyy]

I love you so much dr lets get married

[@DrMungli]

😀😀 you are proposing a married professor. Sorry to disappoint☺️☺️

[@medlocks6732]

May ALLAH bless you