Christine Jacobs-Wagner (Yale, HHMI) 2: DNA segregation & active intracellular transport in bacteria

[@numericalcode]

These are deep, fundamental questions.

[@ilmarinen79]

Fascinating. I really love these 'next gen' simulation animations.

[@genegray9895]

It's fascinating that bacteria use their DNA as a cytoskeleton with seemingly all of the same abilities as eukaryotic cells. I'm curious if there are cell behaviors that are chemically organized at smaller spatial scales by the DNA.

[@Manava2012]

Why Should only one partition complex diffuse?

[@imh3r3now1]

+Does itMatter One of the ParB-parS complexes is attached to the old pole by a semi-understood complex of proteins. The mechanism by which the second partition complex avoids also being tethered to the old pole is not known as far as I'm aware, but I would assume it is simply stoichiometric (i.e. there is only "space" for one partition complex to bind). I make this assumption because I know that the second partition complex actually is also tethered (by several proteins, including TipN) once it reaches the new pole.

[@williamholmberg6692]

Hi, is there a video on ParMRC (type II)? or could someone explain it to me?

[@kseniaalexandrova5298]

Thank you for your lectures! Lectures are really helpful for exam preparation on the same topic!

[@yangliu1985]

This is helpful! Especially the simulation

[@vantinhnguyen9297]

Helpful video! thank you so much!

[@palomafuentesrobert9617]

Thanks!!!! it was a very helpful and clear video!!

[@myambition2313]

awesome video!!!!

[@videosformybrain3606]

very good, i have a huge crush now.