Countercurrent Exchange Mechanism in Kidney Animation | How Medulary Hyperosmolarity is Maintained?

[@239TaniyaJasmine-fz5xk]

Just finished your renal physiology playlist. This channel is an underrated gem.

[@joquinhadagraca]

Thank you for editing the videos again with that voice! For those of us who are not native speakers of English, it is much easier to understand than your original voice! Please keep editing videos like this! I'm from Brazil

[@NonstopNeuron]

Yes. I am planning to go ahead with an American accent more in future. Thank you for the feedback. It helps me understand you (my viewers).

[@loganathan.n3781]

Excellent Explanation .. keep rocking

[@swapnapais8379]

🎉🎉 very good explanation and illustration

[@beaparajit6128]

I have never ever seen such a beautiful explanation literally loved it keep making videos one day u will make history ❤❤❤

[@prof.dr.habibrehman7354]

wonderfully explained

[@samionita2008]

Thank you.

[@IXXIIAN-om-jas]

In descending limb only water goes out but it is impermeable to solute. But u r saying that solute enters descending limb.

[@NonstopNeuron]

It's capillary. Not the nephron.

[@chalithadival2012]

What are the Softwares that You use to produce videos sir?

[@NonstopNeuron]

Affinity designer, Blender, PowerPoint, OcenAudio, InkScape mainly.

[@chalithadival2012]

@@NonstopNeuron Thank you so much sir❤️ Best wishes from sri lanka

[@NonstopNeuron]

Thank you

[@siddhrajshinde2143]

Your animation and teaching skills are just awesome ❤🤌

[@RaghadMohammed-cq2rs]

Why is osolarity in the end of ascending of vasa recta slightly higher?

[@NonstopNeuron]

Newly absorbed solutes

[@RaghadMohammed-cq2rs]

@NonstopNeuron Thanks for replying ❤️, but does that mean solutes go out but in small amout that is not important compared with wich is trapped in bottom and when you said nwely reabsorped as i understand the newest 300 mosol but the mechanism always makes equilibrium so i think it must go out with the last equilibrium🙂, and my last question there is no ending to this process i mean not like multiplier am i right?

[@NonstopNeuron]

I am not completely getting what is your exact doubt but I think this might help. Think in terms of math. When the medullary hyperosmolarity is stable: the quantity of solutes entering through descending vasa recta + solutes reabsorbed from nephron = quantity leaving through ascending vasa recta. When the medullary hyperosmolarity is developing: the quantity of solutes entering through descending vasa recta + solutes reabsorbed from nephron > quantity leaving through ascending vasa recta. So solutes get trapped in medulla. When the hyperosmolarity is being washed out: the quantity of solutes entering through descending vasa recta + solutes reabsorbed from nephron < quantity leaving through ascending vasa recta. Means more solutes are being removed from medulla than that enters. So solutes get washed out from medulla and decrease the osmolarity.

[@beaparajit6128]

​@@NonstopNeuronwow got it ❤❤🤌😭