Nephrons - Filtration and Reabsorption Basics

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Summary: 1. Blood from the renal artery enters the renal capsule, where approximately 20 percent of the blood plasma is filtered into Bowman’s capsule. 2. The filtrate then moves through the proximal convoluted tubule, where about two-thirds of the filtered water is reabsorbed back into the bloodstream, along with essential nutrients, to maintain their concentration in the blood. 3. Next, the filtrate descends into the loop of Henle's descending limb, where more water diffuses out into the bloodstream through osmosis, facilitated by the high concentration of salt ions in the medulla. 4. As the filtrate ascends through the loop of Henle's ascending limb, sodium and chloride ions are actively transported out, establishing the high salt concentration in the medulla, which drives water reabsorption from the descending limb into the bloodstream. 5. Finally, as the filtrate reaches the distal convoluted tubule and collecting duct, additional water reabsorption into the bloodstream occurs, contingent upon the presence of antidiuretic hormone (ADH). *the pituitary gland will release more or less ADH depending on the water levels in the body, in order to regulate how much of the water gets reabsorbed, this process is called osmoregulation.*

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Glad it was helpful!

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You're welcome! I hope your exam went well!

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You're welcome, and thank you!

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You’re welcome! I appreciate the comment. I found it a really hard concept to wrap my brain around because the textbooks I have make it super complicated. It was hard to distill down to main ideas, so it’s rewarding to hear it was helpful!

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Awesome, I'm glad it's been helpful! I'm actually sitting at a coffee shop working on a diagram for a video on the Renin-Angiotensin-Aldosterone System (not sure if your exam covers that topic). Unfortunately, I don't think I'll have that video done before your exam though. Good luck on the exam!

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Wack slides are no good. Glad the video was helpful, and I like the Windwaker pic!

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You're welcome!

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