Nephrons - Filtration and Reabsorption Basics

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[@106four]

Summary: 1. Blood from the renal artery enters the renal capsule, where approximately 20 percent of the blood plasma is filtered into Bowman’s capsule. 2. The filtrate then moves through the proximal convoluted tubule, where about two-thirds of the filtered water is reabsorbed back into the bloodstream, along with essential nutrients, to maintain their concentration in the blood. 3. Next, the filtrate descends into the loop of Henle's descending limb, where more water diffuses out into the bloodstream through osmosis, facilitated by the high concentration of salt ions in the medulla. 4. As the filtrate ascends through the loop of Henle's ascending limb, sodium and chloride ions are actively transported out, establishing the high salt concentration in the medulla, which drives water reabsorption from the descending limb into the bloodstream. 5. Finally, as the filtrate reaches the distal convoluted tubule and collecting duct, additional water reabsorption into the bloodstream occurs, contingent upon the presence of antidiuretic hormone (ADH). *the pituitary gland will release more or less ADH depending on the water levels in the body, in order to regulate how much of the water gets reabsorbed, this process is called osmoregulation.*

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[@franeliseo]

Thanks! Just need to talk about each individual enzyme and what receptors are involve, and how they produce the reabsortion of iones and water

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THIS IS THE BEST NEPHRON VIDEO EXPLANATION IVE SEEN. Thanks so much.

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Glad it was helpful!

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I have an anatomy exam tomorrow and the nephron was something that would always elude me. This video put it into simple terms and is super helpful! Thank you so much for doing what you do! (lowkey made the nephron sound interesting)

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