COVID-19 | Pathophysiology

How does the coronavirus (SARS-CoV-2) that causes the disease COVID-19 attack the body?
In this video, Dr Mike explains how the virus gets into the cells of the body and produces cough, pneumonia, cytokine storm, and acute respiratory distress syndrome (ARDS).
Instagram: @drmiketodorovic

[@katelynnm9750]

“When you take a breath in...” *takes deep breath automatically, oddly proud of my lungs for doing such a great job*

[@anonvlogs281]

It's all because of grace of God.

[@qumi369]

@@anonvlogs281 i can’t tell if you’re sarcastic or not

[@NinjaCokeGaming]

this guy explained it so well. haven't been this interested in a science lesson in a long time

[@nadapenny8592]

Ngl I originally clicked because I thought you were shirtless in the thumbnail and I was intrigued by the thought of chaotic science man, but then I stayed for the engaging and informative presentation and overall I was absolutely not disappointed

[@jeffreyramos287]

Thank you Doc for the wonderful lecture. Well, that explains why we as healthcare professionals should not sedate heavily or paralyze these COVID pts. Because when you sedate a vented patient, the blood pressure drops. And the traditional response is give more fluids. And the result is a viscous cycle of sedate, bp drops, then more fluids given and those fluids will go to the lungs. Thus needing more peep and oxygen requirements. As a respiratory therapist, we need to find the happy medium of ventilator settings and some sedation just to keep them comfortable. Thank you.

[@brownsugar85]

One of the best COVID tutorials I've seen!

[@raeez4613]

The only one I’ve seen

[@darrenrichards4840]

Thanks so much for taking the time to post this. I have a layman interest in virology which is to say I don't have a medical background but to have viral interaction with body cells explained so clearly is really interesting especially in explaining why fluid in the lungs is generated and the mechanics behind that. I had no idea it was breakdown of the blood vessels and leaking plasma. Thank you, especially as I grew up hearing old folks in my Welsh village speak about fluid on the lungs and too much coughing leading to scaring. Until your post I didn't understand what was behind this.

[@asokbiswas6833]

The simpler way you explain the pathophysiology is fantastic. Anybody can understand. Thank you.

[@Saltysteele]

Brilliant!!! I'm an RRT boning up on ARDS, and this is the most informative video i've found yet!

[@stephenpowstinger733]

Pathophysiology: I learned a new word.

[@pouyahosseinzadeh985]

I was waiting for macrophages to come in earlier but the scenario didn’t go as I planned in my head! You’re explaining in such a great way that I remember the joy of studying when I was studying biology in university. Thank you :)

[@oswaldotorres5525]

Incredible! Thank you for this explanation. You inspired me

[@justus525]

Hi Dr. Mike! Thank you, this is the best coronavirus video so far. I’ve been watching your videos for my A&P class, you make it so easy to understand. You helped me a lot 😀

[@Veteran365]

What does your fitness routine look like? You get a gold star for health good sir!

[@kirklazarus3493]

Thanks for explaining it the way you did! Great video

[@lemonsauce3078]

It would help plenty to have links to research articles in the description or in the comment section, as references or for further reading

[@eleanormystim1641]

saving me minutes before my pathology exam

[@elyay7203]

I love people like you sharing important information for free

[@eeeesss1217]

A Big THANK YOU for making this video, it was asked in my VIVA examination.

[@petalbobo]

he's so quirky and cute. like the awkward moment at the start and end where he just smiles lol

[@howtomedicate]

Amazing video. The audio could have been louder though😅

[@truthseeker5642]

Would you be kind enough to review how the virus in its relation to Cytokine Storm causes issues with coagulopathy? Thank you!

[@MisaelB17]

It is unknown yet. They know there is a strong relationship between thrombosis and inflammation and that those two processes reinforce each other. But that's about it. I will leave you a link of an article of the COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET). www.sah.org.ar/pdf/covid-19/083-20_pre-publishing.pdf

[@jonathansanchez8802]

Amazing video. Appreciate the time and effort!

[@mondayrassone9528]

Excellent. Thank you. Clear and concise.

[@my-3j-3k-ot7]

Thanks Doc Mike.. wonderful lecture..Now I understand the concepts very well..You are a great teacher ☺️👍🏻

[@maryamtebib7276]

you explained it amazingly, thank you so much for all the effort, you are helping a lot of students.

[@nicksonsebastiananthony7861]

Awesome description, great understanding about pathophysiology of COVID 19

[@nayeemanusrat1015]

sir, that was mind-blowing. tomorrow i have an exam, and this helped me much♥️

[@Nadasistschoen]

Great explanation! Thanks from NZ

[@FiveandCook]

Thanks doc...great explanations

[@RA6162]

Thanks for the video ! Ur a genius for simplifyiing medicine in sucha manner !

[@adetokunboakinseye3666]

Outstanding presentation!

[@Cardiologist89]

Superb presentation... well done

[@RadityaNugraheni2405]

Thanks a lot, Doc!

[@liv6050]

wow, your explanation on what surfactant does was really helpful, finally get it now thank you heaps

[@ragegamervideos]

Awesome video, been trying to get my head around the whole coronavirus thing and watching this video really helped clear the gaps and understand it so much better. Great explanation cheers!

[@Saravostoo888]

Great explanation. Cheers!

[@dalyamajeed8710]

Amazing video !!thank you

[@Tanvir_Mahmood]

Excellent explanation as usual, but somehow you are very underrated

[@urbanprojectz]

Needs to have better sound, seems to be a youtube thing.

[@sokmkim5057]

Adam Webb sound is too low

[@einsteinzvice517]

#agreed

[@valentinaleeharrellcardona9076]

Your accent inhibits your pronunciation rendering misunderstandings of your explanation. Try losing the accent. God bless you and your house.

[@valentinaleeharrellcardona9076]

@@sokmkim5057 Einstein was an extremelly high educated man he never spoke that bad. Listen to Zack he will lead you to better pronunciation.

[@shireen9323]

well done doctor💜

[@hosannautube]

good and clear , easy to understand. thanks

[@varshiniiyer4255]

Beautifully explained!

[@francesrebolledo]

Hey! Just wanted to say I was watching your videos when I was reviewing for the licensure exams, and now i’m a registered medical lab scientist! So great to have watched this, as always, so easy to follow 😊

[@nicksonhyeladendu8085]

this is excellent. Great job

[@Thanh_Thien]

Thank you. Your video is very helpful and it's also easy to understand.

[@user-lg7od4se9s]

Very great video ! easily to understand and memorize!

[@ayeshaarshad9702]

Thank you so much for your such elaborated video. It helps to clear my concepts.

[@dhillonamarsingh5033]

Great Information Thanks

[@dawnmcnamaramdpharmd5662]

Great teaching!

[@mwasie]

excellent!

[@jonjiecasenas4218]

Very helpful.. Thank you so much!

[@jenniferbalboni]

Thank you!

[@quincymongare2289]

Great summary!

[@anonvlogs281]

Good explanation, thank you.

[@lisanatale2377]

Great lecture! Thank you!

[@tamaldeb1565]

Nicely explained. Thank you.

[@anupamjoshi4051]

u are the best,sir

[@riteshchaurasia8016]

Thank u for this

[@DrMurphy2273]

Very good. Thank you

[@karunamane2626]

Thank you so much

[@PeacefulWarrior1720]

i took good notes and learned more about sars-cov-2 virus.thanks #stayhome #alertnotanxious

[@ashutoshkholia3439]

Thanku for this.....👏👏👏

[@shivanandanmathan7998]

Excellent and very clear Dr

[@anuruthiya]

very thorough !!

[@sharongeorge3622]

Brilliant explanation Mike

[@johnmichealreinante3278]

Thanks for the explanation. Its very helpful.

[@josephmusumbu8310]

You may experience difficulties in handling your nursing assignments please check on me for help. [e-mail] Thank you.

[@IK_59]

Very nice lecture

[@anshusinha1203]

Oh god , you are amazing 🤩 Keep uploading such lectures

[@serametlhaganeng1258]

Thank you Doc

[@madamebrunhilda5105]

Very good, clear explanation.

[@creativeCanvaswali]

Amazing expansion 😊

[@poonamkhairnar6479]

Nicely explained..thanks

[@apass81]

Thank you

[@amreshyadav2758]

great info mate...

[@ryanh.nguyenmd5357]

Realistically video, thank you so much, Doc

[@amrapalikyatham8858]

Thanx.. Very good

[@rachealnyaguthii2240]

Great video

[@benjaminfox7105]

Hey Dr. Mike and Dr Matt - Thanks ever so much for this detailed explanation of the pathophysiology of SARS-CoV-2 - My wife and I really enjoyed it! Nice one! In other news, my placement in ED was unfortunately cancelled (no more students in ED) - Totally makes sense from a risk mitigation perspective. I've been redeployed to the renal ward - Which of course is, AWESOME. The renal system is grouse! Your previous videos are helping heaps in this placement. Thanks mate. Take care!

[@DrMattDrMike]

Nice! Best of luck in your Renal placement!! Have fun and keep us updated!

[@davidyohanna2229]

Wonderful lecture

[@simontremblay3591]

good job !

[@saphimal1]

Great video!!! :-)

[@christopherhennelly7486]

Thank you Doc, I t gave me a good understanding. I really appreciate you having done. I buried so many during the AIDS crisis and feeling like were are in the medical storm of a lifetime once again.

[@Daniel-zb5lm]

amazing video really good explanation but the only thing I could focus on was his biceps and triceps :) XD

[@jigyasabhasin4182]

Nice explaination 👍

[@mariealv95]

perfect thank you

[@TheAshcops]

good work

[@chikazulu102]

You're amazing please make a video about dialysis hemo and peritoneal

[@jjn3533]

Thank you very much👍👍👍

[@drrenukam1389]

Nice presentation

[@robertopena1037]

Thank you very much, useful video

[@chavviattri7204]

Thanks sir 😍😍

[@evanderkolli1234]

Informative indeed.

[@starritaelovesbts]

this is sooo good! pls keep making videos 😊

[@josephmusumbu8310]

You may experience difficulties in handling your nursing assignments please check on me for help. [e-mail] Thank you.

[@rcarnes1988]

Can you do a video on the microvascular thrombotic properties of COVID-19

[@harnakreal7394]

I really understand the pathogenesis of the virus. Thanks very much.

[@activitychannels3167]

Very very informative

[@ThomasRohde]

Thanks a lot from me in Germany! Very clear information.

[@MrMinister77]

Thanks Dr. Mike this video was really helpful. One thing that I didn't quite understand is, how does the virus inhibit the anti-inflammatory effects of AT 1-7? Does it use up the ACE2 proteins on the type 2 cells thereby reducing their availability or is their another mechanism I'm not understanding?

[@kodiaghaegbuna272]

You really helped me through school last year and I see you are still doing amazing videos. Thank you..🙌🙌

[@MehediHasan-gz8dp]

Nicely explained. but audio shoulde be more loud and clear!🎉

[@yanglee789]

Thanks a lot, you make it so easy to understand. I don't even know much about medicine.