COVID Vaccine side effects are Good! *Mostly

[@suzellefourie8431]

Hi Friendly immunologist. I love your videos they are very informative. I would have loved to get Novavax but unfortunetely our country enforced the vaccine man dates so I only had the one option, they did not even let us choose. I had to take the pfizer vaccine or I would loose my job. We can only buy food and visit a pharmacy. Bit no other stores or venues. I had my first dose on sunday. Arm got sore after a view hours but the next morning my head felt strange. It feels like a tightening grip or pressing down on my brain. I struggled through work. It felt like I was going to faint all the time. At one point I laid down so I dont faint. I keep on feeling as if I am going to fall down. Especially when I do some work or walk or act fast. Tuesday it did not go away and went to see a dr. My blood pressure was 154/80 its usually 115/70. Dr told me the symptoms will pass within 3 days. I had no fever but some headache that comes and go.I still experience the same side effect today Friday. Five days later. I went to see another dr. Did not tell I had the jab but I was asked about my vaccine status before dr will let me in because they only talk to you on the phone before they let you in. This is now fully vaccinated drs who wears full ppe and dont want to see you unless you are vaccinated. When she heard I had one jab she let me in and took my blood pressure and checked my heart. Blood pressure was 118/80. I was just told to wait it out. It could take 2 weeks. Previous dr said 3 days. Did not prescribe me anything for my symptoms. In your opinion should I worry? Our country also tells us it is safe to get the second dose in 3 weeks it was usually 6 weeks. If the second dose is worse than the first what will happen then? I dont veel normal. Please answer all my questions.

[@friendlyneighborhoodimmuno7192]

It sounds like you have a lot going on, and I can tell you are concerned. I'm a PhD not a medical doctor, so you should try and find a doctor you trust and go with their opinion. It sound like your blood pressure was high for 3 days and then went back down to normal by day 5. I know it might be tough to get days off of work, but I would recommend not working for 1-2 days after your second shot. You could try and get it on a Friday and rest for the weekend. We also get the second dose 3-4 weeks afterwards. It sounds like your major side effects were headache and high blood pressure. The second shot will likely give you a fever and muscle aches. My husband felt sick for 6 hours, I felt sick for 24 hours, and my mom felt sick for 72 hours. Everyone is different. I know some people that had zero side effects. Try and take it easy and drink lots of water. If you feel faint you should contact your doctor again. You could also journal how you are feeling.

[@janfourie209]

@@friendlyneighborhoodimmuno7192 Hi. I am not working at the moment on sick leave. Took it slow since I started feeling bad.Seen 2 dr's but as soon as they hear I had the shot they stop asking me about my symptoms they just say it will pass. One said 3 days after 3 days no change so I went to see another dr, she said 2 weeks. Both did not want to look into why I felt like fainting just said I will be fine and gave me my slip to pay and said goodbey. The moment I do physical work like hanging the laundry my head feels worse and I get that falling over feeling, and feel extremely tired. Also if I walk fast or act fast with sudden moovement. Have never felt like this before. How do I know if I have enough oxygen in my blood? What causes the pressing feeling in my head? It keeps on feeling so even if I sit still. Gets worse with moovement.

[@Lisa-vp4yt]

Would you be able to do a video on what causes myocarditis and why there is a potential link with vaccination?

[@adonm6998]

What are your thoughts on the recent study that showed mRNA remained in the bloodstream 28 days after mRNA based vaccination? Why would this be the case? should we be worried?

[@varyolla435]

Meh! Your bloodstream already contains loads of various proteins. The "protein spikes" created by the introduction of the vaccine mRNA into the cell are not capable of replicating themselves. Thus any which might evade neutralization by the subsequent antibodies generated in response to inoculation during the inflammatory phase following injection would simply break down on their own after a time as all protein structures do. Proteins like everything else = have a "shelf life". p.s. - the actual mRNA segments which lead to spike protein creation are fragile as all mRNA is. So those segments will degrade after a few days while as alluded to above any protein spikes created will also break down in time.

[@realvicguerra]

Hello, I received the first the Pfizer vaccine on september the 30th, I felt really well with little pain. Nevertheless, the third day at night I started to feel a tingle in feet, legs and arms and felt like i had no force, I started to worry and couldn't sleep well, the next day I had heartache and tachychardia but I believe these further symptons were because of stress. That same day I went for blood tests and the doctor said the signs were all ok, and told me it was probably an neurologic allergic reaction, I took some meds and vitamins and the symptoms started to went off the next days. I told another doctor recently since i got covid recently and told me it was a weird reaction (the tingles), and to wait a little in taking another shot . Would you think is safe another mrna shot? I'am hesitant and probably considering taking Novavax shot in a few months if authorized. Thanks in advance!

[@partdeux992]

how come the friendly lady didn’t answer u?

[@varyolla435]

Immunological reaction to vaccination typically takes 24-72 hrs to fully develop. Once your immune system has started to generate IgG specific antibodies in response to the presence of an antigen it can take up to 1-2 weeks for enough to be present in your bloodstream to make you immune. As to side effects. Many viral infections can trigger cardiac symptoms - aka "myocarditis". Myocarditis simply means that your cardiac tissue has incurred some inflammation for some reason. So in the case of infectious diseases this means the virus in question is able to infect the cells of the heart - just as say the Influenza virus can readily infect the cells of your respiratory tract. Since the Covid virus attaches to "ACE receptors" in the body which your cardiac tissue is full of = it can infect the cells of the heart. So a likely reason why younger people are experiencing myocarditis following mRNA vaccination is owing to their age and hence = activity levels. An older more sedentary person does not typically "stress" their heart as a younger, more active person does. So just as say a smoker becomes short of breath with exertion - so more active people seeing their hearts work more might incur more noticeable symptoms as a result of the presence of myocarditis compared to older people. What matters is that it is typically mild and transitory requiring no intervention. They might feel it for a day or two but for most it usually resolves quickly. Unless it results in significant chest pain and/or difficulty breathing then it only bears monitoring and taking it easy for a time.

[@joeycan6801]

Once more great job in educating us about our immune system. Thank You and stay safe

[@ernestodelatorre859]

Great information, I have a question what about people with allergies, Is it too much for the body or immune system to handle allergies and COVID shot since our immune system is always on gun. Can a COVID shot help with allergies or on the contrary can it be harmful by the way I have chronic allergies to pollen and honey greens and is there a certain or better vaccine than other for allergic people oh and I also get a few steroid shots including prednisone treatment in the fall to help allergies Thanks

[@friendlyneighborhoodimmuno7192]

Great question! I have awful allergies and I got the Pfizer vaccine. I did not set off my allergies. If you have allergies to Polyethylene glycol you should not get the mRNA vaccine. That seems to be the main allergy issue. You should always consult with your primary doctor though! The COVID vaccine will not improve or worsen your allergies.

[@friendlyneighborhoodimmuno7192]

You would need to time your vaccine to not be close to your prednisone shots. Some people have said their doctors have recommended Novavax. A few things to talk with your doctor about!

[@yjg201100]

Thanks for the video. However... My friend's mother bled on feet after vaccination. AZ My brother in law had breathing issue for a week after Moderna jab. My colleague's son had serious pain after vaccination. I don't remember what vaccine it was. All of them were not counted. To me the side effect probability could be 1 out of 200. Side effect Stastics data were already distorted by the system.

[@amourfout]

Thank you for enlightening the masses, so to speak:) and doing it in a fun way, too! I just had some chills the other night after the second shot, so I'm happy my immune system was boosted:) Please don't be discouraged by bitter and silly comments and continue spreading the light of science!:)

[@partdeux992]

how could u say peg? these bubbles are LNPs with peg. LNPs are the main player… lol

[@josephstanski5180]

Thank you sooo much - "Knowledge is Power".

[@friendlyneighborhoodimmuno7192]

Thank you for watching! Glad it was helpful!

[@akhilesh4524]

Very well explained. I am a medical practitioner in india recently finished my medical school , now preparing for specialization and also seeing a lot of covid patients at the moment . I was wondering if u are planning on making videos on other covid 19 related topics say Coagulopathy In covid Role of neutrophil lymphocytes ratio Different inflammatory markers in covid . Are videos on other vaccines in bag anytime later ? Say AstraZeneca or other viral vector based vaccines Vaccine induced Prothrombotic immune thrombocytopenia Would love to see your views on such topics and I am sure these will help lot of medical students as well as newly inducted professionals like myself in understanding the depth of covid and it's complication . Thank you.

[@friendlyneighborhoodimmuno7192]

Thank you and congratulations on becoming a medical practitioner! Although I am sorry it is under such difficult circumstances. Thank you for those great ideas for additional videos. I think the Neutrophil Lymphocyte ratio is a good idea. I’ll try to get that out next week. I do have a video on Thrombocytopenia if you want to check it out, but it is more about the immune system reactivating Immune Thrombocytopenia (ITP).

[@terjeoseberg990]

“Tell your muscles to shake” Shivering? Is it noticeable?

[@partdeux992]

you covered like one se mechanism out of hundreds. 🤪

[@freakeses]

Awesome explanaiton!!

[@Atari23]

This is so informative!! Thank you 💙💙

[@friendlyneighborhoodimmuno7192]

Glad it was helpful!

[@dharma_star]

So,what about blood clots? Is it an issue? Any percentages?

[@friendlyneighborhoodimmuno7192]

Associated press and WebMD say there have not been any blot clots reported yet.

[@friendlyneighborhoodimmuno7192]

The Novavax vaccine doesn’t have any blot clots reported yet. The Moderna vaccine has had 8 cases out of 300 million doses given, and Pfizer has 3 cases reported. This is according to the CDC in the US.

[@应无所住而生其心]

@@friendlyneighborhoodimmuno7192 Hi, Friendly Neighborhood Immunologist, I like your videos, in Europe, we also see some cases of blood clots happened on young healthy women. Although it's very rare it causes some fear already. Can you explain why do vaccines can cause blood clots? thank you!

[@friendlyneighborhoodimmuno7192]

@@应无所住而生其心 Hi Connie. Thank you for your kind words and good question. Right now it seems like the viral vector vaccines might cause rare blood clots in women. But that data is hard to interpret because people going about their daily lives have blood clots too. The vaccine percentages are often not higher than the average expected in the population. Having said that, there are two possible causes. One I have a video on Thrombocytopenia, people who have underlying immune issues against platelets are at risk for bleeding and blood clots. Because the vaccines cause powerful immune responses they can reactive older immune cells and exacerbate auto-immune conditions. I should mention this is rare like 1:5 million people. There is another hypothesis, but it's not proven. Its possible that the viral vector takes the COVID message into the nucleus where is it processed differently than the mRNA vaccines, and through the processing the antibodies are made to a slightly different spike protein that happens to look a bit like blood cells. Then the antibodies stick to blood cells and blood clots happen. It's possible but all of these are rare circumstances.

[@应无所住而生其心]

@@friendlyneighborhoodimmuno7192 Thank you for your prompt reply, what you are doing here is very meaningful. your videos make it much more clear for me to understand how does human bodies work. looking forward to your new videos.

[@closertothetruth9209]

now theyve got a medication for cytokine storms

[@friendlyneighborhoodimmuno7192]

Sort of. Steroids are a better treatment for cytokine storms and they don't thin your blood.

[@terjeoseberg990]

Do the lipid nanoparticles enter muscle cells too? Or only macrophages?

[@friendlyneighborhoodimmuno7192]

Lipid nanoparticles enter any cell membrane made of lipids and that's all your cells, muscle and macrophage alike.

[@SykoEsquire]

@@friendlyneighborhoodimmuno7192 This is exactly why I am not a fan of mRNA “vaccines.” The LNPs aren’t selective enough. The last place I want an S1 factory to be is in my heart cells, which I believe is contributing to all the heart issues. It is this indiscriminate nature, that makes this exceptionally risky. I know they can design the LNPs to be more selective, but we aren’t there yet and I believe it irresponsible to roll this out in its current form.

[@varyolla435]

@@SykoEsquire Poor fear-based assumptions....... The "spike protein" used by the Covid virus - and what is generated by the mRNA vaccine = has a high affinity for ACE2 receptors. ACE2 receptors = are ubiquitous in the body being especially found in cardiac/vascular tissues. Ergo even if the LNPs did not have an affinity for cardiac tissue = the subsequent spike proteins generated and released into the bloodstream would. Ergo upon encountering cardiac cells those proteins could attach and subsequently trigger an inflammatory reaction the same as if the virus had invaded the cell. Thus as noted by others the LNPs being little more than emulsified cholesterol are similar to your cell membranes made from lipids. That similarity allows for the permeability required to allow the LNPs to enter the cell to release the mRNA triggering spike protein generation. This as noted occurs anyways when the Covid virus infects your cells = any cell with ACE2 receptors on it. Ergo people infected with actual Covid also incur symptoms like myocarditis - save for it is seen more often with natural infections than following vaccination while the naturally infected typically incur a more severe subsequent outcome. Far more people develop heart symptoms from catching Covid than from vaccination. The problem is not the LNP = it is the spike protein and its affinity for the receptor. 🤨

[@ruili96]

Vaccine-enhanced disease Available data do not indicate a risk of vaccine-enhanced disease, and conversely suggest effectiveness against severe disease within the available follow-up period. However, risk of vaccine-enhanced disease over time, potentially associated with waning immunity, remains unknown and needs to be evaluated further in ongoing clinical trials and in observational studies that could be conducted following authorization and/or licensure.

[@friendlyneighborhoodimmuno7192]

Yes we shouldn't let our guards down and stop collecting data on important things like amount of antibodies produced and immune memory.

[@scart121]

No the side effects are not good. What about the long term effects. Death blood clots strokes, cancer, etc.

[@friendlyneighborhoodimmuno7192]

The goal of this video was to explain the most common side effects (fever, muscle aches, and chills), and explain how that is the feeling of your immune cells becoming activated. Yes there are rare and serious side effects in 0.01% of people who are vaccinated. Blood clots are a concern in viral vector vaccines, but not the other types. Cancer has not been reported due to vaccination. It takes years to develop cancer. I have videos talking about thrombocyotopenia and cancer if you are interested.

[@elenafaurescu4673]

No, this is not normal You should't have these kind of side effects.Don't misinform public!

[@friendlyneighborhoodimmuno7192]

Hi Elena, yes it is normal. I think you are concerned because other traditional vaccines do not usually cause side effects. So I would like to give you an example. ChiIdren in the US get the MMR vaccine. This is a traditional vaccine because it is viral, but this vaccine is a live virus which is uncommon. Children often get all of the side effects I listed here (fever, muscle aches, chills) because the MMR vaccine is a live virus which is stronger than other vaccines. The only reason this side effects are happening is NOT due to the mRNA, it is due to the fact that it is strong vaccine. The worry from the vaccine creators was that a weaker vaccine might not cause your immune system to make enough antibodies to prevent severe COVID symptoms. One more point, these side effects are also happening because the shots are spaced so close together. Usually the world isn't in a pandemic and we can wait several months before the second shot. www.cnn.com/2021/04/01/health/covid-vaccine-side-effects/index.html www.abcactionnews.com/news/coronavirus/virus-expert-says-covid-19-vaccine-side-effects-are-a-good-sign

[@friendlyneighborhoodimmuno7192]

If you have any other concerns I would like to discuss them with you further. Take care

[@edgarbleikur1929]

Your ignorance is palpable. You've obviously done no research into vaccine injury statistics.

[@ruili96]

@@edgarbleikur1929 please don't be mean. The doctor has donated her time explaining to us how vaccine work in theory. In theory, the variables are constant. In real world, the variables change and vaccines which are safe in theory cause a lot injury such as myocarditis if you use Pfizer and blood clotting Astrazeneca.

[@edgarbleikur1929]

@@ruili96 I'm objecting to this immunologist spreading misinformation and nowhere have I been mean about my objections to the spread of false information in this KZbin channel. I originally wrote: "Your ignorance is palpable. You've obviously done no research into vaccine injury statistics." There is no possible way of saying: "you're lying and covering up the extremely dangerous nature of vaccines and your should be held legally accountable for your lies and spreading misinformation" Any more nicely than what I originally wrote.

[@m24_4]

I was just passing by looking for common sense, but clearly not to be found here.

[@whoami252]

Your comment has no common sense, sure. Why did you choose to insult yourself like that?