I m one of the main authors who wrote the paper. Thanks for explaining this so well and easy! Scientists need more people like you haha. Keep up the good work as a scientific communicator for the scientific community !
@nicknorwitzPhD2 ай бұрын
This is always the best sort of reply. I'm glad you felt I represented the data well. I appreciate there is always a tension between story telling for the public and fairly representing the data. My aim is always to strike that balance to the best of my ability. Glad you enjoyed the video.
@gwb84452 ай бұрын
As a child I ate what we had. It was mostly starches like beans, bread & potatoes. As adult I ate typical American diet and gradually ballooned up to 400 lbs. After 5-years as ketovoire I have lost almost 200 lbs. Now I only crave my meat with some spices. And I enjoy some coffee & black tea ... and an occasional diet soda 😮
@nicknorwitzPhD2 ай бұрын
That's incredible! What a journey!
@gwb84452 ай бұрын
@@nicknorwitzPhD It was easier than I thought. I was never hungry and the weight came off steadily, unlike the "diets" recommended by doctor! Learned about keto/carnivore from KZbin. Wish I had learned about this much earlier in life!
@shelleyhodgkinson13412 ай бұрын
Super interesting..we need more of this kinda thing. Love the way you present complex concepts
@nicknorwitzPhD2 ай бұрын
Appreciate it! Thanks!
@Deanriley2 ай бұрын
I was crazy for brownies (with walnuts) as a kid and into adulthood, but noticed thirty years ago or more that I never ate a brownie that tasted like I hoped or remembered from childhood. I gave up on brownies and anything that I had a food memory of since it was always a disappointment. I’ve never regretted what I did not eat, only what I ate that didn’t meet expectation. Don’t know how this fits with this info; but wanting things that always disappoint seems an addictive response to sugars.
@cynthiagilbreth13522 ай бұрын
Great points about regrets , thanks.
@gwenj54192 ай бұрын
That's so true. There are many things that don't taste as good as what I remember too. But I also have a few things that always taste as good.
@vonticehembree60832 ай бұрын
As always , Nick , thank you for your great takeaways on explaining the new and relevant scientific studies !
@nicknorwitzPhD2 ай бұрын
You’re so very welcome!
@capnceltblood53472 ай бұрын
Channel is growing fast Nick grats. Good to see somebody bringing new discoveries in the field to the forefront. Rather than just regurgitating and parroting what every other channel is.
@nicknorwitzPhD2 ай бұрын
Thank you. Deeply appreciate it.
@lucia_cossu_voiceteacher2 ай бұрын
The last taken is important and central also in my field: I am successfully pioneering the contributions of our musculoskeletal system into voice and voice production - both as result/practice and rationale in conferences. The not widely, at now, appreciated thing is the happiness and artistic 😊individual freedom that complex systems have as nuances and different options when understood the logics. Reductionist models, for nutrition as for voice, are a prison in the few options they can account for, if not plainly wrong for many individual context, to be managed and solved. Let’s love again complex as a possibility of so many adaptations! Cheers to you and all maintaining it in a rational mechanism based effort way, 💪🏻💪🏻🤗🤗🤗
@mattfisano2 ай бұрын
Nick- you need to look into the mechanisms and benefit of using glp-1 like Mounjaro. I lost 215lbs in 13 months all while exercising and started lifting weights 4 months into it. I monitored with CGM while lifting. I have found a hack with it. If you lift for 45-60 minutes with 30-45 minutes cardio, all while on a fasted morning. Incredible strength and stamina while on Mounjaro. I think it’s speeding up fat burning by forcing it into glycogen in the liver then the Mounjaro gip is forcing it into the muscle as full. The process is amazing if true. I spike my blood sugars while hard exercising up to 120-130, afterwards I come down to low 80’s. I start in the high 80’s. Post meal which is zero carbs. No movement in blood sugar for 2 hours. Maybe it moves 5-7 around 4 hour mark.
@capnceltblood53472 ай бұрын
Lawsuit filed against makers of Ozempic and Mounjaro ... Good Morning America... Look into that.
@nicknorwitzPhD2 ай бұрын
I already have a video unlisted and loaded to go on it! Interesting new data on how chronic GIPR activation on fat cells improves metabolic flexibility… keep an eye out for that video
@kayeszymanski69452 ай бұрын
For me, if I see a dish of candy on co workers desk, I can walk right by and not want any. However, if I witness others taking some candy, I immediately want some. Must be FOMO on my part. Thanks for the video Dr. Nick!!
@homomorphic2 ай бұрын
What i find interesting and which is implicit in your first scenario is that candy should obviously be desirable. It should not. Fructose is a toxin, the natural response of the body is to be repulsed by toxins. The problem is that somehow our whole society has become fructose addicted and just as the idea of shooting opiates into ones veins is repulsive to a non addict, it is desirable to the addict. Candy repulses me. It is repulsive, because my human instinct (developed over millions of years) informs me that isolated fructose is toxic. I am not repulsed by fruit because that same instinct is "aware" that non isolated fructose is not toxic. We will of course eat honey when we're nutrient deficient (as a survival mechanism) but I am repulsed by honey (at least significant quantities of it) when my body has adequate amounts of all nutrients. The tricky bit of fructose vs opiates, is that non isolated fructose is found in many nutritious foods and thus the potential for fructose addiction is much higher for any individual than opiate addiction, because fructose is almost always nutritient adjacent.
@nicknorwitzPhD2 ай бұрын
Feast On Meat Only? 😉
@kayeszymanski69452 ай бұрын
@@nicknorwitzPhD Yes, and pastured eggs plus ghee!! 😃
@Vintage_GenX2 ай бұрын
Hey Nick, another great video that struck home for me. Working with my doc, I just took my first dose of Tirzepatide (GLP-1 receptor agonist). I do not have a weight problem but do have some stubborn fat that will not go away. My doc suggested to micro dose (5mg) for a couple of months to see if it could help. Your comments on the effects of the GLP-1 was very interesting. I do have a big sweet tooth and told my wife years ago never to keep sweets in the house, but I do indulge in 92% dark chocolate which keeps me from falling off the cliff. Within 24 hours of taking the first dose, I was amazed at the total lack of desire to eat anything sweet. It is as if a switch had been turned off. I can see how people who have a weight problem want this drug. I can't imagine what this does for someone who has serious blood sugar / weight issues at the full 20mg dose. Anyway, thanks for another deep fact base dive on this issue.
@cvwhr23 күн бұрын
Everyone around was having fantastic weight loss with Ozempic. I tried it and it made me ravenous! I upped the dose a couple times thinking maybe that dosage was the problem and I still felt like I was starving. Keto, on the other hand, after I'm on it for a few weeks, I am immune to temptation and often forget to eat.
@GladysAmelia2 ай бұрын
Thanks for explaining that article, it didn’t make sense initially.
@nicknorwitzPhD2 ай бұрын
You’re welcome
@Discostick552 ай бұрын
Keto has been the only diet that has worked for me, because it quiets my head and stops these constant sneaky thoughts about food. Genuinely thought something was wrong with me for the longest time, as my thoughts on carbs sounded like what smokers thoughts sounded like when they described quitting. I lost 80 pounds on keto and at my goal weight, I thought I could make smarter choices from then on and stay at that weight, but still go on dates, have a beer, a side of fries, share some m&m's at the movies. I could not. I wish I could partake in regular society without turning into a carb craving goblin :(
@cynthiafasulo3828Ай бұрын
Thank God I'm not the only one...
@corteltube2 ай бұрын
Getting in touch with ourselves..being cognitive. Good stuff. ☺️
@scotchbarrel44292 ай бұрын
I train this superpower regularly on the waking up app; noticing thoughts, its a worthwhile skill to learn, especially useful in analyzing stressful situations. My Kryptonite food is hard to get due to geography, but island food is my kryptonite, junk food doesnt work anymore, must be getting old 😂
@loremipsum68522 күн бұрын
I don't have a culinary kryptonite because I practice Intuitive Eating. I honer my hunger and cravings, balancing with gentle nutrition which creates a balanced, non-adversarial, relationship with food.
@sebastianhoracioforondagon88132 ай бұрын
Genius man. One day I want to write a paper with you
@nicknorwitzPhD2 ай бұрын
What's your feild? Project proposals?
@sebastianhoracioforondagon88132 ай бұрын
@@nicknorwitzPhD I am a young scientist of 19 years old, soon to do my phD in clinical biochemistry, my interests are biogerontology, nutrition-guided metabolism, cancer and biophysics are the research areas that I focus on. Clearly because of IBS I started LCHF diet, all the symptoms went away and now I am researching the topic rigorously. I read your papers because I am also a LMHR with LDL cholesterol at 289, HDL at 80, VLDL at 9 and triglycerides at 39. As for projects I can expand the research in LMHR in Colombia and evaluate in different populations with low BMI, different ethnic groups to see this metabolic and physiological response.
@LifeDIY2 ай бұрын
You can actually explore some of your brain activity at home with a Muse headband. :) I appreciate this video and how you emphasize that there's no one-size-fits all with health and nutrition. I'm really interested in how eating carnivore, for example, may impact your satiety hormones (compared to a diet that contains more of a variety of meat, fruits and vegetables). There are some people who say that they're hardly hungry when eating that way or doing an elimination diet, but there are others who are endlessly hungry & end up going back to some other way of eating. I did an experiment with carnivore as an elimination diet and I feel like my hunger and satiety hormones are out of whack since then and not functioning as they used to and I'm left feeling always hungry, though I am working on adding more foods back in. I looked into some research studies on different foods that trigger GLP-1 more than others, in addition to gastric emptying speed when eating different types of foods, the thermic effect of foods, etc. and it's all very interesting. If you could ever touch on these topics, that would be greatly appreciated! Thanks again for all your content!
@nicknorwitzPhD2 ай бұрын
Definitely need more studies on carnivore diet. Unfortunately understudied. I think the research landscape will be quite 'evolved' in that respect in a decade... let's see if I'm right.
@cheffatgrams2 ай бұрын
Very Interesting Study review and analysis! Thanks Nick
@nicknorwitzPhD2 ай бұрын
You're very welcome!
@OscarCuzzani2 ай бұрын
Excellent video! The messy soup (our brains) is a great allegory of our psyche. You’re positing a cognitive approach to read inner desires. Quite an endeavor! Thanks to your video, I was able to recognize the pre and postprandial drives, the need for an ice cream after a heavy meal, the guilt and rewards of fasting. The fight of my Id with my superego etc. even the history of the need for an ice cream dating back to my infancy! Complexity makes us heroes if we just can keep our weight within a few pounds in a year. I think that we can control GLP 1 by thinking in the “right way “ I wonder if we can also control IL-11 the same way.
@nicknorwitzPhD2 ай бұрын
"Complexity makes us heroes if we just can keep our weight within a few pounds in a year." - what an interesting thought!
@robyn33492 ай бұрын
Thank you! ❤
@nicknorwitzPhD2 ай бұрын
You're very welcome Robyn
@67sdd2 ай бұрын
Very cool thanks!
@nicknorwitzPhD2 ай бұрын
Welcome 🤗
@DroppingBearVictim2 ай бұрын
Did Anthony Chaffee ever get back to you about you hosting a debate/discussion between him and Chris Plant Chompers?
@nicknorwitzPhD2 ай бұрын
I told them both I would middle man and help to set it up. Both parties seemed open. It's in their hands now. PlantChompers said yes, provided a neutral/trustworthy host. Anthony was trying to determine what about the convo would be productive because - I hope I'm representing him fairy - he felt Chris's video was more of a personal attack with some misinformation about his credentials, than science focused. To be clear, I'm not inserting any opinion here. But - yes - I did ask each man.
@tspicks43602 ай бұрын
I've been eating whole plant foods, Esselstyn style (no meat, no dairy, no eggs, no oil) for the last 11 years ... I don't have any "culinary kryptonite" at this point. :) I like what I eat, and am turned off by heavy, greasy, fatty foods ... ugh, take it away. So it's all pretty simple and self regulating. Took about a month to get there, initially, then just easy peasy.
@nicknorwitzPhD2 ай бұрын
So happy for you!
@Dermsurg12 ай бұрын
It is sad to me we need to give people hormonal mimetics to them to eat "normally" to avoid obesity. We have a crap food supply. Address that FIRST
@vonticehembree60832 ай бұрын
True, half the battle , or more to the point is to explore the crappy food choices, and then adjust to eat a proper human diet
@nicknorwitzPhD2 ай бұрын
Easier said than done… wish it were done tho
@chargermopar2 ай бұрын
Steak is the food that drives me crazy and I have trouble stopping once I start eating.
@nicknorwitzPhD2 ай бұрын
Fascinating. Not a typical comment. Can I ask what the rest of your diet looks like?
@chargermopar2 ай бұрын
@@nicknorwitzPhD I eat beef, eggs, chicken, pork, duck , iguana and ferment yogurt. I also eat cheese, Have been interviewed by several people on KZbin and have made some videos of what I eat.
@hermandejong43092 ай бұрын
I get more and more adds by icecream Ben and Yerries. had to let you know.
@nicknorwitzPhD2 ай бұрын
😜
@chrisavetrano2 ай бұрын
GLP drugs are super effective in rapid weight loss as evidenced by people posting results on FB groups. Example is a friend who lost five pounds per week for 7 weeks in a row. Even if you water fasted for this long you couldn’t lose that much weight that fast. OTHER than the appetite suppression, what the heck is the mechanism? Do the drugs lower blood sugar so low that you actually emulate a type 1 diabetic? I can’t find the answer anywhere but I bet you could!
@nicknorwitzPhD2 ай бұрын
Start here... more coming: open.substack.com/pub/staycuriousmetabolism/p/4-incredible-facts-about-glp-1s?r=40ekz2&
@kayeszymanski69452 ай бұрын
@nicknorwitzphd Yes but the “weight loss” is mostly muscle/lean tissue.
@andredupuis91572 ай бұрын
@@kayeszymanski6945not true if you lift weights and consume enough protein.
@embemwАй бұрын
@@kayeszymanski6945 I don’t think that is true. That wouldn’t make any sense physiologically. But speaking for myself I mainly lost fat . Some lean muscle goes since one is not so heavy it is not needed to move one around. Same on any diet.
@jeffschollmeyer52472 ай бұрын
Great content Steaks > Cakes
@nicknorwitzPhD2 ай бұрын
What if they are crab cakes?
@tlewis59012 ай бұрын
GLP-1 and Satiety ! we really need our hormones in order - stay curious : )
@nicknorwitzPhD2 ай бұрын
Stay curious!
@Philly19582 ай бұрын
Can allulose do this?
@vonticehembree60832 ай бұрын
It works for me , dr Ben bikman studied allulose in his lab and concluded it does in fact act as a glp1
@nicknorwitzPhD2 ай бұрын
Anecdotally people find allulose may kill cravings. I don't think it would be via this mechanism, exactly. I wouldn't rule it out. but the GLP-1 bump you get from allulose is smaller than the GLP-1 equivalents you get from semaglutide. I'm sitting on some interesting allulose data. Will share when time is right.
@Umbertomanens2 ай бұрын
“ in vino veritas” ( Ancient Rome saying) : truth is in the wine
@nicknorwitzPhD2 ай бұрын
I don't drink ;)
@aurapopescu18752 ай бұрын
Having been in the ketogenic space for more than 5 years now, I have found (the hard way) that one of the worst things I could possibly do was force myself to eat "healthy foods" I really hated, just because all the clever influencers out there were saying that it was so good for me. For instance, I have always hated red meat, especially beef - since I was a child. But I forced myself to eat it because I thought it was good for me. A little voice in my head was telling me: "you've eaten this horrible healthy stuff, now you deserve a treat"... so I would eat a chunk of camembert cheese as desert... and that's how I started overeating protein, but I thought that was great (even though my body was saying otherwise), since all those clever influencers were also saying "eat more protein!!"...... 🤦♀️ It has taken me years to prioritise listening to my body, even if that means eating mostly fat, cutting out beef, and getting my protein from eggs, high-fat cheese, some fatty fish and a little pork. Not sure this had anything to do with your video... if it doesn't, I apologize 😊
@Nanalyze2 ай бұрын
So in other words, it's the exact opposite of the munchies.
@nicknorwitzPhD2 ай бұрын
Seihcnum
@buddie57202 ай бұрын
I always take a shot of GLP when refueling the car, and I want nothing to eat later.
@nicknorwitzPhD2 ай бұрын
I might have missed this joke... over my head. What do you mean?
@lipr44402 ай бұрын
@@nicknorwitzPhD I think he means liquefied petroleum gas
@buddie57202 ай бұрын
@@nicknorwitzPhD Oh, my bad! I guess our GLP must be LPG for the rest of the world lol. Liquefied Petroleum Gas. GLP for the Spaniards.
@nicknorwitzPhD2 ай бұрын
@@lipr4440 is GLP a known acronym for that? Wouldn't that be LPG?
@karenmiller37712 ай бұрын
I love your posts. You are SO smart..But could you please begin using "titled" as in " the paper titled ......... was so good ". Most people use "entitled" now, but "entitled" means " believing one is inherently deserving" as in an "entitled" Karen.
@nicknorwitzPhD2 ай бұрын
LOL... only because of your wonderful sense of humor 😉.
@condoriris62862 ай бұрын
I can’t grant you that super power 😢
@nicknorwitzPhD2 ай бұрын
😂 curiosity is a super power though 😂
@groooobytooby1306Ай бұрын
Hmmm. My food kryptonite is .. food. I think I’m fkd.
@georgemoonman28302 ай бұрын
Carnivore diet, i get zero cravings now, people can put cakes, doughnuts, pizza, any of the junk i used to crave, right in front of me and i eat none. Down 50kg in 1 year.
@nicknorwitzPhD2 ай бұрын
Amazing!!
@Caladcholg2 ай бұрын
A snydeverse fan, are we? 🙃
@nicknorwitzPhD2 ай бұрын
More an MCU guy... but Kryptonite seemed a reasonable analogy. And I like the Witcher ;)
@Caladcholg2 ай бұрын
Ah, so a Henry Cavill fan ;). I'm more of an mcu (movies) guy myself, but I think a guy like you would appreciate Alan Moore's brief Superman run. Just sayin'. Keep up the great work.
@Crumbling2 ай бұрын
Super video, thanks! Please keep your intonation natural. It seems like you're trying to sound excited and it gets to a point where it simply breaks the flow of a sentence and thought. 'what this graph SHOWS you...' the verb show is not important, it's what comes next. Don't fall for KZbin-speak ever, please 😊 And again, great info, thank you
@nicknorwitzPhD2 ай бұрын
What if I'm actually just that excited about the data?
@Crumbling2 ай бұрын
@@nicknorwitzPhD one thing doesn't exclude the other. Being excited is good. My suggestion is on delivery, my specialty is language. It's an honest suggestion, which I wouldn't be giving if I didn't care.
@petermadany27792 ай бұрын
I will have to ruminate about this food for thought to get the most mental nutrition from it. In the meantime, the good news for me is that going real-food low-carb/keto has eliminated my culinary kryptonite. The information Nick just shared may help me understand some of the mental health benefits keto provides me. For example, I now have a greatly increased appetite during meals and greatly reduced hunger between meals. Since I pre-portion my meals, the increased appetite means I enjoy food more but don't eat more. Reduced hunger means I skip half my breakfasts and don't snack. Before going keto, I would have an aversion to seeing food or thinking about food immediately after eating a big meal; now after a big meal, I can happily think about future meals and even enjoy looking at pastries I will never eat again.
@nicknorwitzPhD2 ай бұрын
I love how you used this to reflect on your own life and eating patterns.
@egg399.2 ай бұрын
Since going carnivore5 months ago my snacking has stopped. 2mad or omad mainly and plenty of fasting is now possible. I couldn’t fast for than 5 hours in the bad old days of standard diet. GKI 0.9 this morning.
@brianwnc8168Ай бұрын
Slow down you're speaking Style so people can digest the concepts along the way to better lock it into big picture memory of Concepts
@nicknorwitzPhDАй бұрын
Feel free to change to 0.75 speed
@pamisntcraiganymore2 ай бұрын
Did you just say one of your favorite ways for testing on mice was drilling into their brain?
@nicknorwitzPhD2 ай бұрын
Sometimes necessary ...
@thebeef12782 ай бұрын
I just condition my mind
@nicknorwitzPhD2 ай бұрын
Mind is based in the brain, a material organ... just sayin' ;)
@thebeef12782 ай бұрын
@@nicknorwitzPhD yup, that's true, but I'm not grounded in just the material world, you can be if that's all you believe. But I will always believe we are more than matter