Doctor Breaks Down Scenes From 28 DAYS LATER (2002) Film

[@DrHopeSickNotes]

Probably should have mentioned the similarities with Rabies virus too... oh well.

[@wreck-itralph938]

Finish cells at work please

[@kieran89uk]

I was about to mention its almost identical to rabies but yeah.

[@altheaunertl]

There's an idea that some of the very old, small village stories of vampires may have in fact been rabies' outbreaks-- the whole aversion to light and trying to bite people situation. And bats are one of the top rabies carriers. I wonder if, before these old village stories, we invented the idea of vampires separately from our knowledge of rabies, or if we simply once called 'rabies' by the name of 'vampirism'.

[@thepotatoman99118]

@@wreck-itralph938 oh yes please!!

[@Timelost_Techpriest]

I was really wondering why you didn't mention the ur-example of a virus that causes delirium and aggression in its host and is also spread via saliva, yeah.

[@LazyMasquerade]

Your theory about the ending is pretty spot on! The original ending has Jim die from his wounds, though this was changed because it was considered "too bleak". You can still find this version on KZbin / in the director's cut!

[@davehoward22]

Watch the normal film and its right at the end of the credits

[@ringzy]

First of all what's up lazy masquerade 😎. Second I think this is also the case. There's 3 endings. The released cut with Jim, Jim's deaths, and then the released cut scene without Jim. Now there's also another scene in a version of Jim's death that shows Jim hallucinating/dreaming as he's dying. I think the released cut is Jim's dream and the death scene in is true, but in poetic fashion Jim's last vision somewhat comes to reality as Selena and Hannah live in that vision finding the planes in the sky and solitude amoungst the border.

[@789syrus789]

“Infected with what?!” “…… *Rage.* “ This line was the biggest highlight of the movie. Just the way he had to pause and say that one word made an impression on me for years. Great way to start a movie honestly.

[@justin99000]

In the directors cut he dies right there actually and Hannah and his love interest leave him while crying

[@DrHopeSickNotes]

Awwww studio made them go with the Hollywood ending!

[@StickNik]

@@DrHopeSickNotes I think Danny Boyle filmed both and chose the happier ending given all they went through, but the studio probably wasn't annoyed :P

[@justin99000]

Yeah it was actually from test screenings saying after everything he went through it was just too depressing of an ending so they swapped it out for a more lukewarm maybe there is hope ending

[@Madayar]

@@DrHopeSickNotes It tested terribly with the test audiences, that's why they changed it. I would also like this movie less without closure. Life's without closure, let movies give me at least some.

[@ajaywill6487]

You forgot the third one

[@franckbrusset]

The graphic novel 28 Days Later: The Aftermath explains that the virus is a strain of Ebola modified on purpose but which went out of control. Hence, the symptoms. Still impossible to display symptoms so fast. 😄

[@franckbrusset]

Also, in the alternate ending they actually shot, they fail to save Jim from the bullet injury, and many people thought it was a more credible ending.

[@franckbrusset]

​@@Cazameilia They're using Ebola as a vector for an anti-rage molecule aiming at crowd control, but when the film starts, they're still trying to figure out why it is having the opposite effect. The rage comes from how they modified Ebola, not the original strain. Rabies wouldn't be effective at spreading the molecule both for crowd control and for a scary zombie scenario, because you absolutely need a bite to get infected. With Ebola infected vomit blood, which makes them even more contagious and makes them look like undead with all the blood. What's more, furious rabies is only 80% of rabies cases, lasts only 3-4 days, and is generally associated with hydrophobia, so it's inconsistent with 28 days later, and it would really look silly if you could repel 80% zombies with common water, or even the suggestion of water and the 20% left would just be paralytic. Also, rabies may take months or even years to incubate.

[@odd-eyes9463]

Yea, which is insane.

[@andrewrobinson8199]

@@franckbrusset its a Frankenstein virus thats stated to be an ebola, rabies mix possibly with bacteria bullshitted in too, the zombies are hydrophobic right after they turn or if they retain their minds, but loose it as/if the virus takes full control

[@lucianaromulus1408]

I let the idea go of it being instant in that it was genetically engineered. I know it's not super realistic but I still love it, it's mostly realistic as far as the closest thing to zombies we'll ever get in real life I think.

[@liquid_pig]

One Finnish name for rabies is actually "raivotauti" which literally translates to "the rage disease". Was just reminded of that when you said "the rage" is a scary name for a virus! The virus in this film strikes me as rabies cranked up to eleven.

[@Kaleysia]

In German it is "Tollwut" which means something like "Crazy Rage" so kinda same here :)

[@owaine-changaming]

Liquid Pig the virus is rabies and ebola combined

[@Anasteroiddestroyer]

Similar to French where "rabies" is called "rage" .

[@doratheexploder286]

In Norway it`s known as hundegalskap, or dog madness.

[@Dreamoooon]

@@doratheexploder286 same. in Thai it's called the 'mad dog' disease.

[@lilsmiles86]

The YT captions made "junior doctor" become "genie doctor" and I had to pause the video and laugh for a good minute before continuing.

[@deanobeany]

Is that a doctor that heals Genies or a fully qualified Genie practicing human medicine? Asking for a friend

[@katmcclaw817]

Cleveland Clinic is the only hospital system I know that only has "healthy" vending machines. Meaning sugar free drinks and snacks.

[@claireeyles7560]

Some of the hospitals in Australia have the same, or during the day they might also have a cafeteria where you can get healthy meals.

[@ananonymousbean2731]

I remember seeing a vending machine with sealed fruit cups in a hospital once, which was cool

[@bobdobalina798]

I know a hospital like that but the ones in staff only area's have the naughty stuff

[@nstorm2415]

In the hospital i work there are some vending machines, but to be honest when im eating or after a hard day at work i want a soda or some juice.

[@Clay3613]

Hello Fellow Ohioan!

[@JoshTyrReece]

Yeah the "no protection gear" thing. That was also something I hated in "The Strain" TV Series. You have highly infectious bloodworms that swim in all body fluids of the vampires. And its enough that just ONE of them gets into you. You even see it happen in one episode...and still the main characters have no friggin problem fighting whole Vampire armies with swords, knives and so on, often even in narrow corridors. Without any kind of real protection.

[@thebiologist8662]

Worse still, the worms are extremely vulnerable to silver and we've had a silver colloid medication since the old times. Cura and vaccine right there and nobody realizes.

[@feb5th]

It was a terrible show

[@evannibbe9375]

Mad Hatters in jeans I guess it has to do with attracting a wider audience by showing more skin 🤷‍♂️

[@RipEagle397]

In the graphic novel, you can see how the survivors cover their faces and eyes for avoid that kind of stuff, like cut of an infected with a machete and his blood go inside your moth or your eyes

[@thebiologist8662]

Fun facts: The fastest incubation time on a virus would be influenza, at around 1 day, more or less. Bacteria can be even faster, depending on the load you get, with as fast as half an hour to develop the disease. One of the reasons the black death is still dangerous even with today's antibiotic is that you can go from the first infection to symptoms in less than a day and then die also in less than another day.

[@NoJusticeNoPeace]

There have been cases during outbreaks of hemmoragic virii like Ebola and Marburg of doctors being found dead, slumped on top of equally dead patients as they treated them.

[@zubiac]

AFAIK the Norovirus incubation time is the fastest ever "recorded" which was a couple of hours (6 or so). It's also one hell of a tough and contagious virus. Withstands even the usual " limited virucidal" disinfectants. You need to go hardcore ("full virucidal") on those suckers to deactivated them

[@deinoswyrd]

@@zubiac can confirm. Had norovirus twice, each time was less than 12 hours incubation

[@pamelaatkinsonscats2873]

My first thought when you said that if there was a zombie apocalypse spread by a virus, we'd need to wear PPE was "Oh, dear, we're screwed, it's probably still sitting in Turkey!"

[@cinnamon4]

In a turkey in Turkey?

[@KubrickFR]

In french, rabies is called 'rage', wich as the same meaning as rage in english.

[@hardwirecars]

i can see why

On est enragés que les anglais aient volé ce mot et l'ont copié directement du français. Quelle manque de créativité! 😂😂😂😂

[@zedzed3533]

I'm French (I watched it in English) so I didn't really notice lol

[@MysteriousAsteria]

It comes from latin rabere (rage, madness) and the English word rabies comes from the same root. Same with other romance languages.

[@andrewjohnson6716]

Good call!

[@hunterivey]

There was going to be a 28 Months Later also 28 Years later, but they got cancelled, it sucks that they were cancelled, because I was looking forward to them.

[@cinnamon4]

I've heard Boyle wanted to create a new film in the series.

[@hunterivey]

@@cinnamon4 Yeah but he dropped the project which really sucks, because it would have been awesome to see a 28 Months Later and 28 years Later.

[@anivmoreno9612]

@@hunterivey But we got 28 months later, what are you talking about?

[@hunterivey]

@@anivmoreno9612 prove it, because they're were no talks about it

[@anivmoreno9612]

@@hunterivey sorry, my bad, confused weeks with months.

[@TimFisheroo]

If I recall the Rage virus is meant to be some kind of an offshoot or mutation of the Rabies virus. Not that it explains the incubation period but the behavioral changes in the infected make slightly more sense. By the way, have you seen the show "The Knick"? It has a lot of really accurate and thoroughly researched early 20th century medical procedures and breakthroughs in it on top of being a really good, albeit medically gory, show.

[@DrHopeSickNotes]

Very interesting, thanks!

[@Hunnter2k3]

Realistically speaking from that, it'd likely have had to be engineered. Probably some experiment to try hack the body from an infection as quickly as possibly, without relying on the spread of the infection but relying more on the reaction from the body, or hijacking some primal survival mechanism. To what extent we could do that is another question. As Dr Hope mentioned, we do know the body can react incredibly quickly to things, not only infections. I don't know if there are any pathways that could be hijacked quickly enough to turn someone extremely violent and primal like that. Not within mere seconds at least. Not everyone either. Some people can get violent (to the extent of committing criminal acts, including murder) from repetitive sound, imagery, touch, certain words, etc. Varies wildly. Whether there is some relation at a nervous system level between all the various triggers is the big question. Things like ASMR, Frisson, Synesthesia, Misophonia and the like may be possible to hijack chemically. If so, this virus could likely be made. Although even then, you could still probably target all of those pathways at once, that's entirely possible. Probably not now, and certainly not cheaply, we're speaking nation state bio warfare levels. It'd be hard to hide it. A typical drug costs upwards of a $1 billion, something like this would be in the multiple billions, if not hitting the double digits, given the immense amount of research that would be needed in trying to target specific pathways. As great as our understanding is, we're a while away from making good functional artificial viruses. Even our gene therapy right now is pretty shotgun-approach.

[@zarayoung3781]

According to the comic, it's mutated Ebola, because blood vomit. I hate this franchise. -_-

[@andrewrobinson8199]

@@zarayoung3781 specifically it says tat ebola is the main vector but Rage had rabies in its engineering as well

[@mo7mdalmutairi]

I think it’s more likely he had an Epidural hematoma which is more associated with traumatic head injuries . Subdural hematomas are mostly associated with elderlies

[@DrHopeSickNotes]

THIS!

[@Satopi3104]

Yeah, my mom had two subdural hematomas (though the first one when she was like max 50 years old so not really elderly, the second one in her mid sixties so arguably elderly) and neither time were they acutely life threatening nor coma inducing. That said, the first one slowly compressed her brain to half its size and the doctor was like “how are you alive!?” So yeah if you have a headache for 6 months, don’t wait to go to the doctor for 6 months lol. And don’t drive yourself to the hospital in such a situation!

[@damionlee7658]

Zoonotic diseases are the bane of my family's life right now. My wife got Psittacosis and Mycoplasma infections from a sick parrot and we had to go through three doctors just to get to one who believed this infection was possible! Despite her symptoms and test results we can't find a doctor to treat the mycoplasma.

[@ayyylmao101]

I'm loving how you go through every possible explanation for the virus spreading and taking effect so quickly XD nerdiness is appreciated

[@aneasteregg8171]

Could I suggest reacting to "Emergency!"? It's pretty outdated as a show from the early 70s, but it tried pretty hard to be accurate and I think it'd be interesting to see how things have changed.

[@khalilgiovanni]

In the first Resident Evil it took Rain basically the entire movie to turn. Despite being bit multiple times. She may have had some sort of immunity, but because she got bit so many times, she eventually turned.

[@elizabethb7195]

I'm so pleased that you've decided to review one of my favourite films. Thank you for all that you do. These videos definitely make my life a little better and brighter!

[@thepotatoman99118]

You know, the cause of the zombie plague in this movie because some animal activist choose to release infected animals without knowing the effects, kinda ironic to think about....

[@Kaleysia]

Do you mean it is ironic because if people would listen to these activists in reallife we would have far less zoonotic diseases because we wouldn't be in close proximity to the animals that give us these viruses. Also they wouldn't be held in close proximity to another in large numbers.

[@jazzx251]

@Hannah Dyson hmmm ... I'm pretty sure the purpose of the research was top secret ... the activists probably thought they were getting cosmetics tested on them - or perhaps medical research for cancer etc. I think it's fairly realistic that they had no idea about the virus. But - surely, releasing hundreds of dangerous animals onto the British public is not a good idea. (and chimps are very dangerous ... they can re-arrange your face in seconds ... especially if they've been brutalised in a lab for months)

[@Annie_Annie__]

This was a really common trope in 90s movies. I haven’t seen it in a long time (maybe not since ‘28 Days Later’, actually.), but this idea that animal rights activists would break in to a lab and just release all the animals in to a city was all over the place.

[@andrewrobinson8199]

@@Annie_Annie__ it was a common trope in the 90s because it was a common occurrence in the 50s and 60s when the research into the testing couldn't be done

[@andrewrobinson8199]

@Hannah Dyson they are now but the crazy "just let them out" trope is spot on for older animal rights activities

[@justin99000]

Fantastic movie, ive always enjoyed the series but the original is a classic

[@JMilMovies]

I know about 28 days later and 28 weeks later, but I was not aware it was a series? I always thought it was just the 2 movies. Are there more in this “series” that I’m unaware of?

[@ThreadBomb]

@@JMilMovies I assume they meant the series of (two) films.

[@arjanpatel4895]

I hope you don’t mean TWD because that doesn’t anywhere close to this masterpiece.

[@justin99000]

There were 4 planned movies and only 2 released however its still known as the 28 days series

[@smashley5687]

Thank you for making this difficult time a little better with your videos! They bring happiness to my day ❤️

[@wheresthepictureidk2817]

I always hate the fast incubation period in most zombie movies. I think if people got infected that fast governments would beable to quarantine areas very quickly. Where as with a long incubation period people would spread the around the world before anyone knew there was a virus.

[@barbara832001]

I think that's the reason there's usually a time skip to all hell breaking loose, because if they showed the progression from the beginning it probably could be contained.

[@Hevybazist]

Regarding protective gear, Selena and Mark, the pair that rescues Jim at the petrol station wear masks, eye protection and thick leather jackets. Masks and eye protection to avoid blood getting into their mouths and eyes and the leather jackets to avoid bites, Selena mentions the jacket thing in the 28 Days Later comic series. Also, the virus was created as a mean to contral agression in human beings, the inhibitor was successfully created and scientists combined it with the Ebola virus for rapid spread, however, it backfired and had the total opposite effect.

[@thumbsup5087]

Please do The Thing from 1982. That alien acts more like a virus replicating an entire host and regenerating teeth, old scars, etc. because in one scene they check for fillings in their teeth to see if they are a copy. 38 year old Spoilers? The last scene has McCready give Child's a drink of alcohol, if you pay attention in the early movie, McCready turned them all into Molotovs. So when he gives Child's a drink it's actually gasoline. The alien wouldn't know the difference and didn't react and McCready laughs because the alien didn't react and thought drinking gasoline was normal. It's one if the best endings and movies ever made about a virus/parasite. Check out "The Thing gasoline theory" and there was also something about Child's breath not showing up in the cold because the alien doesn't breath out carbon dioxide? Something like that. We need a Doctor's opinion! Stat! 😃

[@UnsoberIdiot]

Thank you for your comment. It led me to discover a reddit thread that linked me to a new author- who, among other things, wrote a short story where he tells the story of The Thing from the thing's perspective.

[@RatelRegalement]

Top marks for the arrow placement preserving Jim's dignity when pointing out the lines during the icu scene :D

[@awkwardaquamarine19]

I did learn something from this video, Dr. Hope. I learned that Mother Nature can be scary. From fish eye viruses to zombie mushrooms growing on ants, it's enough to give me nightmares for days on end. Anyway, great video as usual. Cheers!

[@X525Crossfire]

28 Days Later actually had 3 alternate endings: the "first" alternate ending which is essentially the same as the theatrical only Jim died from his GSW; the "second" which is Selena and Hannah arming up and heading back out into London after Jim dies; and a third that never got past storyboards which replaces the soldiers and castle with a shut-in scientist who delivers on the "cure to infection" broadcast, and ends with Jim sacrificing all his blood in a transfusion to cure Frank.

[@drhmufti]

The hospital scenes were filmed on site at St Thomas’ in London.

[@kimberlyterasaki4843]

Jim actually did die from his wounds in the original movie, but test audiences were so depressed after all the horrible stuff in the film that they added that scene, much to the dismay of critics who liked the darker ending. In the comics, Jim still gets the short end of the stick because he gets arrested for killing the soldiers so win some, lose later?

[@travelwell6049]

The post-credit scene shows them trying to treat Jim, but failing. So I guess that was the original.

It is just because we all grew fond of Jim during the movie, and he was the very definition of a human hero at the end. To have him killed with that bullet was too grim and too unjust to endure.

[@blossomof77]

There's comics?

[@andrewrobinson8199]

@@blossomof77 the comics are the original source you should look into them if you liked the movies

[@nonnoyobisnis8705]

@@andrewrobinson8199 They copied it from "The Walking Dead"? TWD started as a comic, too.

[@Bennyboy138]

Great review! There is no way in hell that the rage virus would have an incubation period as quick as 10-20 seconds...IMO a virus like that would boil itself almost instantly, but lets say hypothetically the incubation time took only seconds and the infected were rampaging everywhere - In the film there were infected running around WEEKS after the initial outbreak which is impossible. The infected would drop after a few days max from exhaustion due to constant sprinting with adrenaline combined with insane fluid loss due to continuous vomiting of blood and sweating, and no nutritional intake.

[@maybenaught]

I just realized, if Jim was in a coma, shouldn't he have been mired in waste? It's not like those functions are paused. Would all the sitting body fluids have caused tissue damage and infection at least around his groin?

[@NoJusticeNoPeace]

He was probably catheterized.

[@maybenaught]

@@NoJusticeNoPeace Well that covers urinary waste, but not infections nor fecal matter.

[@NoJusticeNoPeace]

@@maybenaught He was being fed glucose intravenously, so he probably had no solid food to produce fecal waste. He's pretty skinny. We have no idea how long he's been lying there with nothing but a drip. At least days. And sure as hell in the final days of zombie apocalypse, no one was taking the time to run nutritional supplement into a comatose man's belly.

[@maybenaught]

@@NoJusticeNoPeace True. No solids in, no solids out. Didn't put those together before.

[@LulaLinz]

One of my favourite movies, been watching it for years but can't believe I never thought of that ending theory (genius! Makes so much sense) in my defence though by the time the movie ends I'm always going through some anxiety due to the film's musical score, that 'in a heartbeat' arrangement does something physically to me 🙈 Thanks for covering it & really informative!

[@sambland3903]

Great content as usual. Could you do a review on the HBO miniseries Chernobyl? There's heaps of juicy radiation based injuries and medicine.

[@caramellpanda]

I know it’s just for the sake of easy explaining but 28 Days Later isn’t a zombie movie, though it may be categorised as such since a lot of people say it is. The infected are still alive and didn’t die when they became infected, while a person must die first before becoming a zombie. And while a zombie needs their head destroyed in order for it to ‘die’, the infected can die by blood loss, gunshot wounds, blunt trauma, starvation etc. With the RAGE virus, and I’m basing this on when someone is angry/enraged, you’re filled with adrenaline which inhibits how much pain you feel and helps to push your body past it’s normal limits. With the infected, it’s like this but all the time. When the average person is shot once or twice, they usually go into a state of shock - the infected don’t. The adrenaline in their body keeps pushing them so you’ll see (especially in the second movie) it takes multiple shots to down them. You’ll also notice how fast they run and how they can run for a long time, that’s probably the adrenaline too. It’s also suggested in the church scene in the first movie that the infected sleep, hence why you don’t see them walking around 24/7 in the streets like zombies do. Sorry that I sort of went on a whole minor spiel about this, I just really love these movies haha.

[@karaksan]

One of my favourite films!

[@DrHopeSickNotes]

It's a great film

[@hunterG60k]

@@DrHopeSickNotes I'm pretty horrified to find out it's old enough to drink :'/

[@deborahryder7521]

My favourite bit on the film is when he is walking around deserted London. We never thought that could be possible but after having to travel during the beginning of all this, this was what it was like! I have photos from one of the busiest airports in the world and we were the only flight flying that day (20 people on board too) completely empty, so creepy!

[@JMac7395]

The hospitol scene is a deleted scene not included in the original movie release. The original ending was suppose to only have Selena & Hannah flagging down the plane & Jim dying at the hospital. But test audiences didn't like that Jim was killed off. So all three characters were kept alive at the end of the movie & deleted the hospital scene. But once it came out on DVD the deleted hospital scene was included

[@DjVortex-w]

I'm a bit sick of movies where an infection manifests itself impossibly quickly like this. It's way too common. The irony is that the longer the incubation period, the more the disease can spread. Conversely, the shorter the incubation period, the less it can spread. So these movies get it completely backwards.

[@TheCinderfang]

Ya, too fast and it burns itself out

[@evannibbe9375]

Well, in the case of a virus that does not incapacitate its host, it makes sense to have symptoms show up quickly if it can get cells to produce the right testosterone and adrenaline to get its host to fight (or just hijack the cells to create 1 for 1 copies of the virus and PCP at once (which would require some very advanced genetic engineering knowledge to know how to get the edits to always work the same way)). Though that still leaves the problem of not generally having enough of the strain within the saliva being spread.

[@alexman378]

It ups the horror element though

[@neurofiedyamato8763]

Well for a realistic zombie virus, the host must be alive and not dead. But after suffering from an animal or fellow humans attacking it, I find survival of the host unlikely for a long period of time without medical intervention. In that case the only way for continued spread is a shorter incubation period where the infected host can attack others and spread it.

[@zedzed3533]

I don't understand how it is possible that there is no pandemic in the end with this virus

[@skylined5534]

There is a different and probably more realistic cut for the ending where sadly Jim does indeed die. The virus changing behaviour thing also reminded me of a parasite which infects certain types of snails to make sure they get eaten by birds to propagate the parasite larvae in excretia. What's really interesting about that is that there was talk about this parasite also also potentially infecting humans which can make them take bigger risks, say when driving! Super interesting stuff! Great video, really enjoyed it!

[@deliciouzzz_kiwi]

Actually Danny Boyle (the director) did it because at that time uncovered members from PETA showed all theses videos on tv, doctors doing unnecessary and worthless experiments on animals. Also the ALF was in the peak in UK around the 90’s, so he wanted to show that part to make it real and scary, and the movie was absolutely successful!

[@rasmuswi]

A thing that struck me when I watched the movie many years ago was that the infected frequently seemed to be projectile vomiting large volumes of blood. I'm no doctor, and maybe the virus gives the infected some superhuman strength, but my gut feeling is that anyone who constantly vomits lots of blood will not live very long.

[@missluciddreams3472]

I love how he breaks down our favorite movies/shows and makes them more relatable ❤️

[@ArgyleDinosaur]

28 Days Later is really the only Zombie film I like. Zombies are really overplayed in horror movies and TV, but when I watched this there was just something about it that made it seem different and more interesting.

[@MrBanzoid]

Talking about the rapid action of drugs and chemicals within the body. I have diabetes and it has always amazed me how quickly oral glucose can raise blood glucose levels after even a severe hypoglycemic episode. PS... Great videos BTW. I've watched them from the start of hour channel. Keep them coming. PPS... I saw you had a mention in the Times magazine a couple of weeks ago.

[@bjam89]

I really want a zombie movie made by a team who knows what they do. Having a long incubation time would make it so much more scary in my eyes.

[@xDarkTrinityx]

I believe the Walking Dead has a pretty long incubation time comparatively. Granted, I haven't seen it in so long I don't remember if it's from a virus.

[@mitchellsmith4690]

Black tide rising, by john ringo. First incubation long enough to allow global spread...a flu like illness. Followed by a dormant period, then whammy! Psycho murderous cannible phreaks...who rip off their clothes..

[@AlldaylongRock]

Not a movie. But the game Days Gone did something like that... Flu-like at the beginning, then rabies-like plus mutation of the infected people

[@vamvam7690]

The film Cargo with Martin Freeman (I think it’s on Netflix) has a longer incubation period than a lot of zombie-type movies. Once people get infected in the film they set this timer watch that counts down the days/hours they have left. Although, if I remember rightly, the watch counts down to the point where the disease ‘takes over’ the person rather than counting down to when symptoms start so it’s not exactly what you guys were talking about 🤷‍♀️ The main character gets infected and is racing against time and symptoms trying to keep going long enough to find someone who can take care of his infant daughter before he loses himself to the virus It’s a pretty decent film - worth a watch Id say. Martin Freeman is good as usual 👍

[@lafregaste]

you should check the movie "Contagion", I think it has way too many similarities with this pandemic and I love the movie. : D

[@mieyou3850]

Hi Dr.Hope, I just watched your vlog. I will learn your vlog's medical vocabularies in Japanese. Thank you always for your educational talk. I am looking forward to watching your next one. I will look for the film related the medical contents.😄

[@TitanSlay]

Nobody: Comments: Cells at work final episode reaction please! jk I want it too

[@JohnyScissors]

At this point he might as well wait until right before the next season and Cells at Work Black comes out

[@damedesuka77]

Nah. The momentum for releasing that video is long gone. Understandable if he's not doing it anytime soon since he's a full-time doctor and we're in the middle of a pandemic too. Maybe once the new season drops he could pick it up again.

[@JohnyScissors]

@@damedesuka77 Hes going to release it. Check his comments in the comment section. Currently I believed he traveled and is quarentining at home so he's got free time

[@blank-6222]

GIVE THIS MAN A *TON* OF LIKES PLEASE!!

[@blank-6222]

Johnny Scissors Oh I see..

[@bijoychandraroy]

Just a reminder: we still didn't get the CAW last ep reaction🙄🙄 Btw love your content

[@Melphas]

There's actually another ending that never got filmed where Frank in cured via a blood swope with Jim. Love the director's response to that, "what are you gonna do? Scrub his veins out with bleach?"

[@Iden_Elihio_1999]

Woah I have never noticed the little side notes next to the times frames that tell you which part of the vid you are at 😯😯😯

[@XeresKyle]

When you were talking about the altered behaviors of the infected in the movie-- which, FYI, they aren't zombies per sè, just infected-- based on real life infections that hijack systems in your body, one thing I think of is the rabies virus. The rabies virus makes animals ravenous and their behavior changes drastically, and when a human gets bit by an animal infected by the rabies virus, if the human doesn't get vaccinated, they can also start having bizzare behaviors and then they will die because it is a fatal disease. So I think rabies is the closet thing to a zombie virus based on how it hijacks the host and then causes them to want to bite and spread the virus.

[@themightymikeshow1992]

3:41 i think your actully right about the chemicals of the rage

[@Yasviele]

This is actually one of my favorite movies (I love the Main music theme too) and the sequel... too bad we never got 28 years later

[@deinoswyrd]

28 months later is now in the works

[@Yasviele]

@@deinoswyrd I would like to believe you but... It's been too long without updates

[@deinoswyrd]

@@Yasviele bruh. The IP owners have literally said it's happening in the last couple of months. Very easily googled

[@thequalitycomedian7842]

Are you ever gonna return to watch the final episode of Cells At Work? I don’t think you ever finished it.

[@Zerosinker]

there is a cells at work black anime that is in the works

[@thequalitycomedian7842]

Jiolo Macling I know but he never finished the first season. He saw up to episode 12, and never saw the final episode.

[@Zerosinker]

The Quality Comedian yeah...

[@blank-6222]

Jiolo Macling He did a reaction to the manga.

[@SakiNaoko]

@@thequalitycomedian7842 Black is a spin-off from another mangaka, not a sequel

[@beergnomedc]

You definitely should review the film Contagion as well. It's surprisingly on point with a lot of everything that's been happening this year.

[@Mistaboyz]

I really thought he would mention RABIES with how crazy and deadly it is instead of the bird thing hehe

[@DrHopeSickNotes]

I really should have!

[@MsSecretivegirl]

You're so close to the end of Cells at Work! Would you please review the full series? :)

[@DrHopeSickNotes]

Yeh I will :) I'm lining things up for a big Cells at Work thing for you all

[@MsSecretivegirl]

Dr Hope's Sick Notes OMG YOU REPLIED TO ME! Okay. My day is absolutely made! Thank you so much! :)

[@michaelfourie]

Here is one that may be a bit of a challenge: the Wraith Virus from Stargate: Atlantis

[@ThePoshboy1]

That would be a bit hard considering it spans dozens of episodes.

[@michaelfourie]

@@ThePoshboy1 true, true, but it would be interesting to see

[@dhedemadong]

dr hope, your video quality really really improves in this past months and thank you for putting life in danger everyday for the heallth of many :D may god bless your soul

[@robertombricen7966]

Yes, this movie finally! Good to see you are OK too, Doc

[@TheArbiterOfTruth]

Finally, a doctor that mentions food as a part of health. So many doctors say “diet doesn’t really matter” “the standard American diet is fine” when we know that that is BS. Most standard western diets contain little real nutrition, most people are deficient in vitamins like D, C and B, and are also mildly dehydrated and not sleeping enough.

[@andybrown4284]

The guy at the start might not have been using the name of the virus, I always reckoned that given the circumstances he might have just been describing what happens to the infected in an effort to try and stop the activists from releasing the animals.

[@DanielTsosie]

It was mentioned 3 of 4 new infections are zoonotic. It is mostly due to how pervasive humans have become. Making housing by reducing habitats which in turn results in closer proximity giving more contact and hence chance of transmission.

[@luisttriolet8876]

I couldn’t walk after being bed ridden for about 2 weeks. It was kind of like that scene in Kill Bill when B couldn’t walk after waking up from a coma. I had to practice walking with crutches and my blood pressure would drop when standing. As soon as I stand I get a head rush and almost fall over.

[@rxtxnlxrxs]

love the new editing style doc! the big font for the medical terms is really helpful

[@morphman86]

The vending machines in our local NHS hospital actually has some pretty healthy options. Fruit bags, sandwiches, sugar-free juice, things like that. But I think that's a local initiative, and not nation-wide. At least it sounds like it, by your reaction. I've just never been to any other hospital in England, where I've been past the vending machines.

[@2EOGIY]

The funny thing is that patient survived in hospital on a single IV for 28 days. Is this possible?

[@johngingras]

The story picks up 28 days after the release of the virus, but it wouldn't have been 28 days since he had doctors and nurses attending to him. Depending on how quickly society went down the tubes, it was probably a lot shorter time frame.

[@2EOGIY]

@@johngingras Blood transfusion could be the clue. But zombie infestation starts from hospitals. Those are places where infected will be taken.

[@SomeoneBeginingWithI]

@@2EOGIY I think this particular virus is different from a "normal" zombie apocalypse infection because the incubation period is so short, and because the symptoms are so violent. I think with this virus infected people would be more likely to be taken to the police station than the hospital.

[@meretriciousinsolent]

I once had a saline bag that emptied and was left too long and my blood started to travel into the bag. I don't know how far it would have got (probably depends on some physics I don't have the capacity to work out when blood pressure is factored in) but when I see empty bags in things like this and TWD, I always wonder why there's no blood hanging around in there.

[@michaele.4702]

Love your work and videos Doc, you should do contagion if you haven't yet

[@DrHopeSickNotes]

Thank you! I did Outbreak last week; loved it. You can see it here: kzbin.info/www/bejne/nJaTh2mtiqd_ntk

[@michaele.4702]

@@DrHopeSickNotes Yea I had said outbreak at first but then had to correct myself as I mean't contagion. Both good movies.

[@ste887]

fun fact, in the original screen play for the movie jim died and took with him the last hope for humanity as instead of moving to the countryside to signal for help, the remaining survivor threw sense to the wind to wage a war on the zombies

[@eph2vv89only1way]

I have often said the same thing about the junk food vending machines and donut shops in hospitals. There is no reason they can’t offer healthier alternatives

[@miguelortiz3836]

Yes! You have very educational content and the way you have kept us informed during the COVID pandemic has been great but I missed this kind of light material which is also educational but also fun. You should see the second one, it deals with how natural immunity would work with a virus. I think the rage virus is kind of like rabies in the way that it spreads (fun fact in Spanish the virus is called "Rabia" o "Furia" while rabies is also called "Rabia") I don't remember if they say it but a high fever can also make a patient go aggressive and fever is a symptom of rabies although it takes several days or maybe weeks to develop if I'm not wrong. Great content and it is very good to see you are doing fine, take care please.

[@colinwhitlock5148]

Movie would've been a lot scarier if he was on a ventilator when he woke up

[@Jeff-xv6gk]

Why?

[@deathshot7623]

I wonder if he will educate us when Cell at work black is released

[@vteccomplex]

He's already read the manga, so it's all but guaranteed.

[@campkira]

black is another human who old age and at the end of his life...

[@jackdalton2538]

If you don't mind reading sub titles then The Rain is a good virus related series on Netflix which I would be interested to hear the true science behind

[@marijunealejo1780]

HOLY SH! That soldier was The Ninth Doctor! I have seen this movie a couple of times and I didn't realize it was Christopher Eccleston.

[@animikean]

Awh man, great job on this. Have you ever seen “Night of the Comet”, would love to see your thoughts on the doctors in that zombie-ish movie 💕

[@miguelarcanjodossantosmore5564]

The Rage Virus looks like a combination of a drug called Cloud 9 with The Ebola Virus.

[@qpid8110]

Hahaha! 😂 I was just thinking that you should review this. Great video!

[@meretriciousinsolent]

The last time I was in a hospital the café had all sugar free, artificially sweetened drinks, which are disgusting and give me bellyache (for starters, it gets worse later) and no water. Not even cold tap water. No decaf hot drinks either (can't have caffeine either!). Suppose I could have had hot water. The whole no sugar thing needs a rethink if sweetener is going to be the only real alternative on offer. Even if it didn't make me ill, it's bloody horrible tasting stuff. (Edited because I wrote a load of nonsense at first.)

[@TearDownGenesis]

The original ending didn't have him appear at the end, kinda leaving it unknown. I believe they used the one with him there after studio execs or test audiences said they wanted something happier.

[@Tores444]

Something I realized is that even if those chimps weren't infected that first one probably would've attacked and killed that first girl anyways.

[@hilarywhite0]

Very interesting video Dr. Hope, yet again! You’ve saved me from watching the whole film, far too scary!

[@JohnDoe-qs6hk]

Original ending was without jim. He actually died in the end in the original cut. But during test screenings people felt it was a bit too dark.

[@petrapedia]

I have a theory about the speed. You mentioned getting cells to react and cause the symptoms. I have Mast Cell Activation Syndrome. It crosses into the brain and can cause severe cognitive effects including aggression/hostility/irritability. If this is a virus that immediately produces this specific mast cell activation feature-- TURNED UP TO ELEVEN-- All sorts of accessory reactions could happen. Including vasodilation or incredibly leaky vessels that turn the eyes red. Including extreme brain fog and aggression at once. We're talking an extremely tailored sort of... closest analog I can describe is a cytokine storm.

[@mazbt544]

Love ur content doc, keep it up!

[@lilybeth7266]

Adaptability and mutation are key rules in nature. Human beings unfortunately use them just for their own advantages :we easily forget being also rational and emotional creatures. Instincts prevail like in animals and viruses. That said, 100 % agree vending machines are generally boxes of trash in hospitals and schools as well. Stay safe 🇮🇹🍀🇬🇧

[@rosesnow2013]

Love this! Awesome film. The music and lack-of in these movies is so good. Can you do 28 weeks later too??

[@ianmcgeehan4627]

Notice also that after Jim is shot, they seem to crash the car, it the says "28 days later..." Then in hospital.

[@vteccomplex]

Cells at Work Finale please.

[@DrHopeSickNotes]

It's coming soon...

[@kef41]

@@DrHopeSickNotes 😷❤❤

[@oknice4379]

Dr Hope's Sick Notes yes I am so glad

[@thevideogamehunger0134]

@@DrHopeSickNotes Technically they are not zombies they are infected. There is one part of the movie 28 Weeks later where a infected gets really badly wounded. With a wound that would definitely be fatal for a normal person. It's in 28 Weeks later and let's just say it involves a helicopter.

[@thevideogamehunger0134]

@@DrHopeSickNotes So you are from Britain and a doctor. I have a question if a crazy guy out there in the world took rabies, ebola and Covid-19 and mixed them together. Would the viruses cells just kill each other or combined and become more deadly disease that would be more deadly than Covid-19. Also, I just had a thought what are the chances of some ass hole pranking people in Britain during this Covid-19 pandemic pretending to be infected with the rage virus in Britain to scare people. A Rage Virus Prank.

[@mistapitts]

I like how the time line is time stamped in the player

[@user-vn7ce5ig1z]

• 7:30 - The wording there is awkward. It makes it sound like if you don't move for a day, it'll take a week of rehab to recover from the atrophy, yet many people have spent a whole day in bed without problem. You should've clarified that it takes a week of rehab for each _additional_ day that you're in a coma once atrophy has begun. (Though even then, that sounds way too high; it can't possibly be liner, it must be logarithmic, otherwise, after a few months, you'll spend the rest of your life in therapy.) • 8:08 - The vending-machines in hospitals aren't for patiens, they're for the families in the waiting room who need some junk food to stress-eat to calm their nerves. There's the cafeteria for real food if they're stuck there for a while. (Though that's not much better. 😛)

[@travelwell6049]

He did say, when someone is in a coma ... So it it's not just about having a duvet day.

[@berserkirclaws107]

I really like your theory for the ending ! Great video.

[@crimson2knight]

O snap. I just realized that Thomas Shelby is in 28 days later. All those years of crime prepared him well for the apocalypse

[@ArlanKels]

What's funny is there's an anime called Sword Art Online, and even though it's an animated story about people getting stuck in a coma via a video game mental abduction silliness.. When the Main Character finally gets out he struggles to stand and move because of his muscle atrophy.

[@MaliciousMollusc]

There's no such thing as "nerdy" when it comes to a plague. This entire shit storm is a good example of that.

[@FBH991]

I honestly felt like a longer incubation time for rage would actually have been scarier. The minute-long incubation time was just kind of goofy.

[@mechanomics2649]

Honestly, I can relate about you talking about PPE. I'm not a doctor or in the medical field at all but whenever I'm watching movies, especially movies like these I'm wondering about where everyone's PPE is or why it's not being properly worn.