Does Multiple Sclerosis prevent Alzheimer's Disease?

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Күн бұрын

Пікірлер: 60

@MrMikk532 4 ай бұрын

This video is actually super comforting. My cognition is already impacted by MS at 25, I worry about the future. My grandfather, his father, and my great grandfather on my grandmothers side all had Alzheimer's. Seeing my grandfather lose himself was heartbreaking.

@ericag2233 4 ай бұрын

Age 60 with MS: No dementia. No Alzheimers.

@DrBrandonBeaber 4 ай бұрын

👍

@jenadeen 4 ай бұрын

Where are your lesions? In your spine? They say my lesion in my brain is 2cm of damaged (tumefactive) pons (brainstem) but I also have an intradural extramedullary spinal lesion in my T11 that is not officially diagnosed yet but they call it a tumor. I'm hoping it's just damage done from an epidural 18 years ago. Wishful thinking. No doctor has ever explained the paralysis I went through after having my 3rd child naturally where I could not walk for about a week. No ENT doctor has ever explained why I have mild hearing loss in my left ear ( the same side of the body I presented into the hospital with left arm & leg numbness with, which led to MRI)and I now wear a hearing aid at age 42.

@andrewreisinger6860 4 ай бұрын

Professor Gavin Giovannoni recently wrote in his Substack on this topic. He was in agreement with the hypothesis that people with MS don't get Alzheimer's based on his own clinical experience with his own MS patients, combined with his conversations with a pathologist who had done autopsies on hundreds of older people with MS and had not found one instance of a brain having both MS plaques AND amyloid plaques indicative of Alzheimer's.

@DrBrandonBeaber 4 ай бұрын

You actually made a point I had not considered: that a neuropathologist such as Dr. Bruce Trapp who routinely does autopsies on people who lived with MS. I will send him an e-mail asking this very question.

@jodybridgewater3062 4 ай бұрын

I forget words (I have MS), but I usually remember a few moments later. It's like my brain is "buffering" 😂

@Chris-rh9ej 3 ай бұрын

I have the same issue. I just can’t think of the right word for what I’m saying

@braaandooon3166 4 ай бұрын

Just got diagnosed with MS. Shit feels like dementia to me lol. Grandfather developed Alzheimer's. Definitely take MS over that. Subscribed.

@jenadeen 4 ай бұрын

Play the cards you are delt with. Lol😂 thanks for making me laugh after my very first round of Ocrevus today. M S More Shit Bring it.

@braaandooon3166 4 ай бұрын

@@jenadeen I'm tumefactive/RRMS. I'm having fun with it honestly. Have had seizures my whole life. Nice to know it has a name. My neuro is on board for testing me for bubonic plague at my request so I'm glad he's being a good sport about it. Was surprised to find out people still test positive for that, lmao

@kevinobrien436 4 ай бұрын

Got enough with the brain fog ! Whilst the wife also suffers with the fog as one of her menopause symptoms . Forgetful times !

@suzanneknepp849 4 ай бұрын

I am 68 and have had MS since age 39. I find that I have periods where I feel a cognitive decline but they are not permanent or progressive. My greatest concern for the future is that I will develop significant permanent mental deficits. I spend an hour or two daily “exercising” my brain by solving crossword puzzles, jigsaw puzzles, word games and other activities that work “my little grey cells” as Hercule Poirot so eloquently describes his crime solving methods. I subjectively find that my thinking and expressive skills are enhanced by puzzle solving, whether it be mathematical or alphabetical in nature.

@DrBrandonBeaber 4 ай бұрын

Exercising the brain can only help.

@harmcity9934 4 ай бұрын

been waiting for this one

@gldiego 4 ай бұрын

My mother has Alzheimer's, my uncle had it too, and I have MS. Thanks for the info. Regards.

@DrBrandonBeaber 4 ай бұрын

Hopefully you have to protection against it.

@lisalikesplants 4 ай бұрын

I'll take it

@OddinaryOne 4 ай бұрын

Yep, me too!

@stuwhite5597 4 ай бұрын

Interesting, though. Neuroinflammation in MS --> abnormally phosphorylated tau accumulation but without beta-amyloid deposition (Ann Neurol. 2020 Apr; 87(4): 556-567). MS ~ secondary tauopathy ... ? does earlier life exposure to abnormal/allotypical tau in MS induce neuroimmune-mediated protection against normally phosphorylated tau in AD pathogenesis?

@TotalRookie_LV 4 ай бұрын

Aren't we also more resistant to plague? I've heard predisposition to MS is sort of remnant of the Black Death - those, who survived had higher chances to develop MS, so there are trade offs - some good things bundled with bad ones.

@eloknu 4 ай бұрын

My boyfriend read some papers about it. So I heard about that too

@debraindxb 4 ай бұрын

@@eloknu Interesting!

@sandra85 4 ай бұрын

Hi Started having some cognitive impairment years before I was diagnosed with MS at age 57. I am now 69 and have had two neuropsychological exams about 14 years apart. I am still in the mild cognitive impairment category.

@jackschitt6235 4 ай бұрын

This reminds me of something I read about interpreting headlines that make the news. If u hear that smokers r less likely to develop dementia and u r a smoker u might want to tell yourself that continuing 2 smoke is ok because the last thing u want is dementia. But u need to read the article to understand the explanation because smokers r less likely to develop dementia because they r more likely to have died of lung cancer and other things b4 reaching the age when dementia normally starts.

@TheRobynbrown 4 ай бұрын

I had a friend with MS - he had alzheimers as he aged into his fifties! B12 and B1 in the Benfotamine form are vital for anybody with MS.

@HurricaneHeather 4 ай бұрын

Very interesting information. Age 61, diagnosed at 59, finally. Father recently died from Parkinson's and Lewy Body dementia. His sister died with an undetermined type of dementia. Parkinson's on mother's side, too. My cognitive decline seems to be MS related. The last MRIs showed no brain atrophy. My short term memory has always been an issue since I was a kid and has gotten worse. With that said, I have strategies that work around it, developed over years. The one thing that is new that happens when typing. "for" comes out as "fo r" now. This disease will test your mettle.

@dinos6348 4 ай бұрын

My friend I have MS too and I'm from London UK. I am on ocrevus just to suppress my immune system but I strongly recommend you get the sunshine as much as you can

@brianrose8085 4 ай бұрын

This is REAL science to help people. It’s cool stuff. I always thought of doctors as the scientists that use the awesome powers of science, the various anatomies, medications and pharmacology and in depth knowledge of the human body and conditions to initiate treatment. Lastly it’s amazing to have the ability to be able to go toe to toe with insurance companies to get medication approved for the patient in the office. I would imagine that must be a hassle at times

@lclingo3209 4 ай бұрын

I'm 43 with MS and have had severe cognitive decline in the last few years.

@DrBrandonBeaber 4 ай бұрын

Hm. Unfortunate. What kind of cognitive symptoms do you notice?

@thaliaventouris3855 4 ай бұрын

I started taking Lions Mane and have noticed a difference with cognitive issues.

@SaraC-us5ky 3 ай бұрын

My grandpa, same side of the family I’ve inherited MS from, died of Parkinson’s disease.

@Robin-me8fe 4 ай бұрын

So maybe not everything about MS is bad 😀? ECTRMS starts today , i´m interested about the news from there. Probably you make a video about that ,right ?

@DrBrandonBeaber 4 ай бұрын

I'll definitely follow up anything presented at ECTRIMS

@roberture5903 4 ай бұрын

ÑVery good video Dr Brandon, I do remember Dr Terry wahls mentioning dementia along with MS and I always thought that dementia and Alzheimer's we're basically the same

@jenadeen 4 ай бұрын

Hi doctor Beaber, I WOULD LIKE TO KNOW MORE ABOUT TUMEFACTIVE MS treatments and are they different due to size? Why are the lesions so big? More inflammation?

@inesvicic5388 4 ай бұрын

Thank you for this very interesting article. My mother had vascular dementna, certanly not Altzheimer because her cognitive tests were much better on cognitive tests when they were performed second time, and because of clear MRI and cerebral angiography results, which strongly pointed to vascular disease, or atherosclerosis. I am 60 years old with MS duration of at last 24 years, no dementia for Now, interesting history of big depression in the same months in which MS was diagnosed. Altough disease have diferent pathology the brain is the same and I allways connected depression with strong brain inflamation which could trigger the MS.

@uptoeleven 4 ай бұрын

Depression is strongly correlated with all brain-based conditions, from stroke to Parkinsons and is extremely common with MS - at least as common as fatigue with MS.

@marybethcully5883 4 ай бұрын

Interesting…love any research that may help anyone…Alzheimer’s is such an awful disease. I’m 62, MS for 30 years and brain fog isn’t an issue either.🤷‍♀️

@stuwhite5597 4 ай бұрын

Excellent! Should offset my ApoE3/4!

@klbklbklb 4 ай бұрын

Wait, so it’s in our favour, but then other studies say no that’s not true, and then you say you don’t have much faith in these papers…so which is it? What is even being said? By the end of this video nothing is being said? I’m confused. Must be my MS cognitive processing problems. 🤷‍♀️

@stonz42 4 ай бұрын

Interesting topic. I’m curious if MS patients are more at risk of other neurological conditions like Parkinson’s. Although, I’d be skeptical of the studies as well.

@DrBrandonBeaber 4 ай бұрын

I'm not aware of any association between multiple sclerosis and parkinson's disease. In rare cases, people with MS can have "rubral tremor" related to brainstem lesions which can mimic parkinsonism.

@debraindxb 4 ай бұрын

@@DrBrandonBeaber That's reassuring. My dad has Parkinson's and my daughter has MS. I like to think it's true that she has less chance of developing Alzheimer's. As someone who is studying nursing, she sees many patients with dementia and it scares her.

@user-allex000 3 ай бұрын

@@debraindxb Hi! Sorry to ask, but your daughter has both ms and also studies medicine? If so, does ms impact her ability to learn or work for more hours? I'm interested bc this is the path in career i'd like to follow as well but i don't know if i will be able to.

@kelster1316 4 ай бұрын

I have Tumefactive MS anybody here knows anything about that type of MS? 😢

@jenadeen 4 ай бұрын

I do too.

@jenadeen 4 ай бұрын

All I know is my diagnosing neurologist of tumefactive in the brain immediately had me on steroids and mentioned DMTs in the next sentence at her clinic. But I am on Ocrevus and I have not been to the clinic.

@Jerusalem_Warrior 4 ай бұрын

YAYYYY! 🤗 ❤️ ‼️ One down. 🙄🙏

@jonm4501 4 ай бұрын

There's MS dementia, isn't there?

@Chris-rh9ej 3 ай бұрын

I’m no expert but I can’t find any information on “MS dementia”. I found articles correlating the two, but nothing about that term. Maybe that’s just a colloquial term used to talk about cognitive decline in MS?