Double stranded break repair - Non homologous end joining explained.

Double stranded break repair - Non homologous end joining explained- dna repair mechanism.
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[@CORPSE77]

I just filled my notebook with what you said about this mechanism. Thank you a million my amazing teacher for this wonderful wonderful explanation. I just subscribed and I will have my textbook and notebook filled with what you explain. We appreciate you

[@DrArindamGhoshBiochemistry]

Thats great. Keep in touch ☺️

[@atomyforeverybody]

how cute lecturer teaching biotechnology lessons:))))) xox loved your style!!!! take care and thank you ;)

[@DrArindamGhoshBiochemistry]

😁😁

[@ayeshasahar4772]

U really made this easy to understand 🤗🤗thanks keep it up

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@preetisoni2510]

I've been following u since a while...the way u explain the topic is amazing... Thanku sir... It helped me alot

[@DrArindamGhoshBiochemistry]

Glad to be in touch ☺️

[@jaimemonaco2874]

Hey Dr. Ghosh! Thank you SO MUCH for posting such great content. I am currently taking Molecular biology online and my professor doesn't give the students much to work with with the power-points that he posts. Your videos are straightforward and give me clarification on all of the things that I am trying to learn/understand. You're the best!!

[@DrArindamGhoshBiochemistry]

I am glad that my content was helpful. Keep in touch ❤️

[@priyankasharma2196]

Sir u r doing great work... I'm studying for Csir net and your videos are helping me a lot... Thanks sir

[@DrArindamGhoshBiochemistry]

All the best for your exams dear.

[@dreamer1500]

Very clear and nice explanation........thank u so much sirrr

[@DrArindamGhoshBiochemistry]

Glad you understood the topic 😃

[@mailingmyself6971]

Sir you made it very easy.. thank you so much 😊

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@ksrkarthik9556]

Loved your explanation sir. Understood the process very well. Thank you so much for helping out students in an easiest way possible.

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@ankitachowdhury5268]

Very informative lecture ❤️

[@DrArindamGhoshBiochemistry]

Thanks

[@moumitapanda7921]

Well explained, sir

[@DrArindamGhoshBiochemistry]

Thanks ☺️

[@kop-hw8pb]

Why did the feature of translation into Arabic not allow me, I have an exam, and your explanation is clear, simplified, and full, and I am Arabic

[@subhamkarmakar3320]

Trimming of ends is done by enzyme Artemis

[@DrArindamGhoshBiochemistry]

Yes but for first year mbbs Students, you will get the desired marks even if you don't mention Artemis. But thanks for completing that missing piece of puzzle ✅❤️

[@shagulfuad8107]

Thank you!! ❤️❤️

[@DrArindamGhoshBiochemistry]

Welcome 😇

[@dipendrarauniyar2535]

can you post the video with the questions asking in medical license exam with their explanation . indian medical council exam questions also ok , or talk about the questions asked from that specific topics u thaught like as some usmle videos

[@DrArindamGhoshBiochemistry]

Okay will try to make one video..

[@윤나리-d1e]

Dr. Ghosh, Thank you for this great content! I have a question. If double strand break occurs by Cas9, do DNA strands break uneven? or exactly blunt? I want to know how CRISPR/Cas9 system knock out gene expression exactly.

[@DrArindamGhoshBiochemistry]

Nothing special about cas9 it's just a nuclease like any other nuclease. So the double stranded breaks are uneven and repair is error prone :)

[@gabs.lita.]

thank u so much!

[@DrArindamGhoshBiochemistry]

👌👌

[@cck09]

Thanks for sir ❤️❤️🎉🎉🔥🔥

[@DrArindamGhoshBiochemistry]

Always welcome

[@sankhabachar9193]

sir love ur explanation very much.... sir 1 question is this also called recombinational repair !

[@DrArindamGhoshBiochemistry]

Sorry for delayed response but the answer to your question is Yes!

[@sankhabachar9193]

@@DrArindamGhoshBiochemistry ok sir thank u

[@DrArindamGhoshBiochemistry]

Most welcome.

[@KIRUBAKAR]

Sir, does trimming of the end and ligating leads to loss of dna information, even if breakage is dna at gene can leads to inactivation of gene?

[@zeeshananjum6471]

loved your explanation

[@DrArindamGhoshBiochemistry]

Glad to hear it ❤️

[@manuelalmendarez2232]

Doesnt it mean that there are genes missing.isnt that dangerous since its like a mutation where parts of a gene are missing?

[@DrArindamGhoshBiochemistry]

Yes absolutely. This type of DNA damage is very harmful to any species

[@debikachatterjee1627]

Ku 70/80 is equivalent to rec b and rec D?

[@DrArindamGhoshBiochemistry]

No 😅

[@debikachatterjee1627]

@@DrArindamGhoshBiochemistry okay

[@drksreelatha3650]

Does such repaired gene work

[@DrArindamGhoshBiochemistry]

Yes.

[@shankarreddy6247]

❤️

[@DrArindamGhoshBiochemistry]

😁

[@tanu6464]

Wao

[@DrArindamGhoshBiochemistry]

Thanks 😃

[@FarhanKhan-xe1qz]

👍

[@DrArindamGhoshBiochemistry]

😇

[@jayjayokucha7220]

does this result in genomic diversity?

[@DrArindamGhoshBiochemistry]

Yes 🙂 if it happens in introns.