TRETINOIN VS SKINMEDICA 😮 SHOCKED BY THE ANTIAGING RESULTS

[@terryberg3906]

I took advantage of the mask requirements and began using a tretinoin prescription in Apr 2020. I certainly had many weeks of dry peeling skin but the mask covered it up for me. I am so grateful that I now tolerate tretinoin. My skin improved so much, it helped with my confidence as redness disappeared, pores improved and wrinkles are minimal. Next week I will turn 59 and I love my skin more now than ever.

[@bettyng9880]

I used and loved tretinoin till my skin became hypersensitive a few years ago from autoimmune issues. Sadly I had to stop. I started using retinol (Cerave) a year ago and switched to adapalene (Avene) a few months ago but the improvements have been negligible. I just got a new prescription of 0.05% tretinoin as I feel that it would work much better for me. Fingers crossed!

[@terryberg3906]

@@bettyng9880 I wish the best for you!

[@gategirl66]

I did the exact same thing! 😅 I can remember taking off my mask to eat lunch at work one day and watching the skin fall down like rain 😳 I called it face dandruff because that's what it looked like 🤮 About a year later someone saw my face while I was eating and was shocked at the difference (I hadn't told anyone i was using it). Before long, word got around and people began approaching and asking to see my face 🤷🏻‍♀️ I'm now 56 and so glad I took the plunge!

[@caseywoodbury3412]

I did as well, and I’m so glad I did!

[@mirinaxo1663]

Good for you! What type of skin do you have, like dry, oily etc.? Thanks!

[@Momofukudoodoowindu]

I LOVE these type of videos. When you delve into studies and the science behind products. More!!

[@Eteraz]

Your skin looks so glowing. I’ve been using Retin A since late teens for horrible acne years ago. No more acne but still use it 3 nights a week.

[@kellyrudd1920]

I love Neutrogena Rapid Wrinkle Repair. Im seeing huge improvements and very smooth skin. I turned 50 this year.

[@dylanbillion917]

This product works

[@pmurphy1259]

I love the SkinMedica retinol products. It’s one of the few brands that specify the retinol concentration and it offers a few strengths (.025, .05, .1%) to allow you to build up your tolerance without guesswork. I’m on Tretenoin now, but I was able to transition onto Tretenoin with minimal irritation thanks to SkinMedica.

[@rocgnzz721]

Skin Skinmedica. Is over the couner?

[@michelemarks5026]

@@rocgnzz721 yes

[@aeducator1]

And its great that they do peer-reviewed clinical studies. Very few companies do.

[@nataliia048]

I'm in a same journey right now, with a super sensative skin and acne. I use 0.25 for 5 month so far, 5 days a week. How fast have you built up your way from SkinMedica 0.25 to Tretinoin?

[@Jade_902]

$300 no way too expensive

[@NancyFosterLouise]

I have been using tretinoin for at least 15 years on and off. The past 3 years I have used it every evening. I have no redness, but I did go through of transition and was very persistent. I have no reaction at the highest potency. I’m glad I did. I’ll be 74 next month and still get compliments on my skin!

[@miaash3870]

Have you had any procedures such as Botox, fillers, etc done?

[@michelleandino3301]

Happy Wednesday 🌺 This is super interesting! I love my tretinoin but it's nice to know that retinol may work well for some people. But they definitely need to do more studies with people of color.

[@DrDrayzday]

definitely!

[@msk-qp6fn]

Totally!

[@WiseFamin]

Agree! Institutional racism in medicine is really depressing.

[@stevdaughtr6098]

I agree.. I really don’t understand not doing it. Anything they test should be tested for everyone.

[@CLOUDTHOUGHT]

I just had a complete body mole screening from my dermatologist. Thanks to your videos, I am taking care of my skin regularly! 💜

[@leslieedwards6269]

I love Skinmedica retinol. Thank you for such a comprehensive breakdown of the study.

[@lovetoadventure2954]

I have been using SkinMedica products overall for about 3 years and love it. It never flared up my rosacea and keeps my skin feeling smooth and silky.

[@katfadel]

What product do you use from skimedica for your rosacea

[@lauragwillim1055]

I have used Tretinoin for over 20 years. I’m a big fan of Skin Medica products and tried the .25 retinol complex then bumped up to 0.5. Hands down my skin irritation is waaaay less and I’m getting excellent exfoliation with the skin medical 0.5. I’ll never go back to tretinoin.

[@lauragwillim1055]

@@user-qe4zj6iu4s yes. The results are better than tretinoin. I’m getting no irritation but good exfoliation. I love the skin medica product!

[@aeducator1]

That's great to hear. Other studies have shown that retinols don't cause the same pro-inflammatory response that retin-A does.

[@joyousenoful]

I’ve tried the Skinmedica retinol at 0.5. Once I started using it regularly, it really irritated my skin causing redness and stinging every few applications. I finally stopped using it because i didn’t want to aggravate my melasma further. I did notice some improvement in skin texture. Now I just use the Olay regenerist retinol cream though because it’s much gentler. Will see if I get benefits.

[@agnesjuhasz7715]

I don’t think that in this case, it would be an issue that Skinmedica funded the study-of course it makes sense that they wanted to prove the efficacy of their product. However, my personal experiece using retinol for 2 years, absolutely no visible positive results. Switching to Differin and using it for 2 years, again, absolutely no visible positive results regarding anti-aging, but positive results regarding acne. Switching to tretinoin- after 7 months, basically new skin, amazing product. Now on year 3, and I will never stop using it.

[@ttthecat]

Preach sister!!! Same experience same product journey!!! I am african american and my skin responded to the products EXACTLY like yours! Only difference is I was also using a 15% vitamin C for hyperpigmentation as well. Still do. Tretinoin for life!!!

[@redapple9488]

@@ttthecat I’m excited to see results! I’m 3 weeks 1/2 into tret. I’m tan skin and also black

[@ayah1541]

Wow!!

[@PercussiveMaintenance]

Thanks for the detailed description!! I started using granactive retinol 4 months ago and considering switching to Retin-A Micro 0.025%(tretinoin in slow release microspheres). Can you please share the tretinoin percentage and vehicle (gel/cream/liquid) that you used/use? And also your skin care routine (whether you used a moisturizer before applying tretinoin etc.)

[@annarebecca3384]

@@PercussiveMaintenance Most physicians will start you on 0.025% tretinoin. It's very thick and just takes a dab for the entire face. It takes a long time to work up to the higher percentages. You use it on bare, clean skin. If I get red and scaly, I will skip the tretinoin one night and just apply a good moisurizer.

[@noneofbusiness7739]

I contacted Skinmedica about this product. They say the product mentioned in the study was discontinued in 2016. It was replaced with their retinol complex which comes in 3 different strengths. They stated “Tri-Retinol Complex and Tri-Retinol Complex ES are no longer available since they were discontinued in 2016. The replacement product is Retinol Complex which comes in three different strengths (0.25, 0.5, and 1.0). Retinol Complex is a separate formulation from Tri-Retinol Complex and utilizes a single form of Vitamin A rather than 3 different forms of Vitamin A (retinol, retinyl acetate, and retinyl palmitate). In comparison to Tri-Retinol Complex, Retinol Complex is stronger even at its lowest strength (0.25). The newer formula was designed to maximize efficacy while also minimizing irritation typically associated with topical retinol products.”

[@estewartdixon]

So which of the three newest options would be best or most comparable?

[@noneofbusiness7739]

@@estewartdixon I didn't ask. They didn't say.

[@HeyyyEverybody]

Thank you for saving me 17 minutes of my life 😅

[@eps3154]

Boo.. why discontinue something that works and is published.?

[@aeducator1]

Exactly. This study was done in 2010.

[@flanamom]

Love this style video! The way in which you present these studies so we regular folk can understand them is so very appreciated too, Dr. Dray. This is exciting news! I am able to get my 0.05% tretinoin Rx from my GP, and fortunately my insurance covers it: my doctor provided authorization for its use by including my hx of basal cell and tret's efficacy in cellular turnover, and my insurance company okayed it, $3.95 for a 20 gm tube is my actual cost. I don't have acne, at age 67 I'm an anti-aging kinda gal, and am very interested in the exciting discoveries being made behind such reputable studies. That you bring us such such interesting and new data in such a "user friendly" way is just one of the many reasons we, your fans, think you're just great!

[@BeckyCantu]

How is your insurance covering it? They don’t cover anything cosmetic. I’m curious to know what diagnosis code your GP used when submitting the RX claim.

[@lkessler1]

@@BeckyCantu she states that she had basal cell which is skin cancer so that is likely why insurance will cover it.

[@paulacalloway108]

Better be careful the cream did nothing for my basil cell cancer, I had to have 3 in hospital surgeries it ate my nose up, the basil cell cancer. I thought the tretinoin would have helped it didn't basil cell cancer is nothing to play with. I learned that the hard way. But good luck and I wish you well flanamom.

[@chrisalmendra4370]

that color is GREAT on you!

[@prestonlepori567]

How is your mom doing? Haven’t seen her on here in it feels like 2 years now! Hope all is well

[@crystalllllll]

I've been thinking about her too. I miss seeing her. She's so lovely

[@irmacardenas1964]

Please do update us on her!

[@0o0Vanilla0o0]

I've been using Avene a-oxitive peeling which has 0.1% of Retinaldehyde. I truly love it and it has become my core product of my night skincare routine. So I'm glad to hear about new studies related to vitamin a and derivatives

[@SingingAesthetician]

That’s really cool, we carry that at the spa I work at but I haven’t tried it yet. Have you used regular retinol and tretinoin? Do you have acne or aging or both? Which works best and what about which is more irritating?

[@SLSpencer]

Me too! Love it

[@sophiekotomski4588]

Thank you. When I go into a store I have a clue on what to get and don’t feel lost thanks to your work. Keep up the great work.

[@nadab4750]

In general, the less irritating an effective product is, the more likely that someone will actually use it more often. A similar product (that is irritating) won't work at all if you buy it and just leave it on the bathroom shelf. 👱‍♀️❤

[@amymarxer6559]

Great point Nada!!

[@honeybadgernasty]

You must be talking about the collection of retinol, tretinoin and retinaldehyde products in my bathroom cabinet! Haha! So true! Good point.

[@amymarxer6559]

@@honeybadgernasty Me too, Bird!! 🤣🤣🤣

[@lebleb9501]

I have use this product - SKINMEDICA and loved but what I really loved even more is.... SENTE DERMAL REPAIR WOW!

[@grnddesign]

SkinBetter has a retinoid molecule combined with lactic acid molecule. It actually made my skin feel plump in the morning since the lactic is hydrating. I think this is a superior retinol to use. Great ingredients in it. I hope you analyze one day

[@derekward3512]

Dr Dray actually did a video on the skinbetter science alpharet cream. Her analysis of it was that the product itself showed evidence of helping smooth fine lines and wrinkles, but not the active ingredient itself, which was the retinoid+lactic acid. She also said the major issue with their studies is that they did not double blind the study, meaning testing one group with the product that has the active ingredient in it, and the other group with the vehicle with no active ingredient in it, so it's really hard to tell what in the product is causing the anti aging effect. Another thing she brought up is that there are other ingredients in the alpharet cream that have been known to help with skin aging, such as glycolic acid and niacinamide. I don't use alpharet personally, but a lot of people anecdotally report seeing better results with it than regular OTC retinol, so I hope one day alpharet does an unbiased extensive trial so that we know if the alphret technology is actually worth considering.

[@joshlum8291]

I believe Dr Dray did a review on it

[@chincaglieria]

I’m sticking to my prescription strength 0.025% Retin A gel. I’ve been using this for about 30 years and it has worked miracles on my skin. Yes, I had to go thru painful times for my skin to adapt, but WELL WORTH IT! So between Retin A, laser treatments, rose hip seed oil and Shea butter, my skin looks radiant. I’m 65 and I’m finally proud of my skin. You would never know that I had bad acne as a teen that made me cry all the time. Also, Retin A has come way down in price for me. I now pay $25.00 for a tube that last many months. 30 years ago it was about $100! Maybe even more than that.

[@miaash3870]

How do you use Shea butter, please?

[@chincaglieria]

@@miaash3870 I use organic Shea butter

[@chincaglieria]

I use about a quarter sized amount of organic Shea butter along with a few drops of organic rose hip seed oil (grown in the Andes Mountains) and rub it between my hands and it instantly melts and becomes sort of milky looking. I rub it into my face, neck, arms, hands, chest, legs and feet. The rose 🌹 hip seed oil is potent and it actually began to fade my dark spots but it was slightly irritating so I began mixing it with Shea butter and together they work . I kid you not, I lived in South America when I was young, and the indigenous Indians used rose hip seed oil thousands of years ago to heal their skin from all sorts of maladies. I can give you the companies that I purchase from if you would like.

[@chincaglieria]

@@miaash3870 don’t forget: Retin A is the most important thing you can use!! I’ve used it for over 30 years and will never stop! I just have to alternate between that and the other two things. Let me know what you decide. Thanks!

[@miaash3870]

@@chincaglieria Thank you. I mean, Shea butter is solid. Do you subject it to heat in order to melt it, or do you keep it in your palm for a while so that it softens itself before rubbing it on the skin?

[@msk-qp6fn]

Wow, this is a really thorough study, albeit its limitations! I guess it would be nice to try Skinmedica's retinol complex, but not if I have to spend more than 100 bucks for the product (product + shipping) when I can buy OTC adapelene (15~30g) for 12~24 bucks. There are also cheaper retinol products which I could buy for around 25~50 bucks. I would just buy those and use the rest to buy sunscreen and a couple of sturdy jeans (because those are good at blocking sunlight for a non upf clothing).

[@rosalina2773]

Oof yeah that price is rough. Wonder how long the bottle lasts. I get tretinoin + azelaic acid formula from Apostrophe and a $75 bottle lasts me like 4-5 months.

[@betsyanastasi967]

Interesting. This would give credibility to the Skinmedica retinol product. I'm curious how the Neutrogena retinal would compare to it, after hearing the research that goes into their products. Thank you for a video that gives food for thought. Have a wonderful rest of your day, everyone!

[@AM-qr4ys]

I use the neutrogena retinol in the grey jar. Fragrance free It works amazing on my skin and I have a lot of lines on my forehead and I’m very sensitive. My skin looks great. Just my opinion. I like to tell people if I use something good

[@margaretochoco2412]

@@AM-qr4ys hello! is this the 0.5% pure retinol one? I just bought mine last week haha

[@AM-qr4ys]

@@margaretochoco2412 hi 😀it’s the rapid wrinkle repair and it doesn’t say how much retinol. Just says retinol SA

[@cathyray3861]

@@AM-qr4ys thanks for this info

[@AMYOLSENSCHOO]

This is great! Thank you for deducing the study for us. Love it! Using The Ordinary 1% Retinol in Squalene. It's great. My skin can take it and it's affordable!!!

[@librarymom3034]

I have been using the Skinmedica retinol for years now. I started at .25% and now I’m at 1%. It’s only irritating the first couple days.

[@madams.5976]

I have tried Tretinoin several times on the past 2 decades but the dry, flakey, sensitive, results were just so bad that I could never I use it on a consistent basis. I also wax so I would have to stop using it at least a week prior. Some people can use it once a week and increase as they go. Well, good for those people. My skin always looked worse than before I started. I’m happy to try something that is less harsh. I’m going to be 63 and you just get to a point where you’re just happy to be healthy and alive. I’ve always took care of my skin according to my budget. The other thing is I’ve never been a sun person. Also I believe genetics has a part in it as well. Love your content.

[@patriciasales8812]

I have been using the Skin Medica 1.0 for over ten years (I am 79). Prior to that I used tretinion for many years, but it became a hastle because of insurance. recently I considered goint back to tretinion. I guess I'll stay eith Skin Medica-no flaking. Thanks for the video-great timing.

[@liss441]

Very interesting - let’s see what other studies say later

[@sarahohara4022]

I used that skin medica retinol for about two years. It was quite expensive but it made my transition to tretinoin totally seamless. I had literally zero irritation.

[@Nikki-rq8mh]

Was there a percent to what one used the skin medica?

[@sarahohara4022]

@@Nikki-rq8mh I think I used .05 and then .1

[@peony70]

Would have been interesting if they did this study on post menopausal subjects.

[@TheHijabi]

Great news!! I got excited just by reading the tittle. I hope companies continue to invest on research to prove what they are claiming.

[@philippillis9393]

I think that OTC retinols absolutely work unless they're poorly formulated by cheap companies. Wherever I use one from credibile brands I get the Same symtpoms and results that I get with prescription tretinoin. I think advantages of Tretinoin is that it's cheaper here than most OTC, credible retinol, it's always fragrance free, it lasts a lot and you know it works. Pros of OTC is that it comes in countless formulas that can suit individual skins better than a tretinoin cream that rarely has something extra going on to prevent irritations like soothing ingredients. A negative aspects of retinol products is that they tend to be expensive and rich in fragrances and useless stuff, so do you research.

[@RVC0902]

I’ve used this skin Medica product before. I liked it. It was $100 though. Now I use retin a micro gel and tretinoin cream. $20 to $30 with insurance in Canada. Use the sandwich method to minimize irritation.

[@21972012145525]

Why do you use both?

[@fallenangelz291]

@@21972012145525 She said to minimize irritation.

[@RVC0902]

@@21972012145525 just because I had ordered both and wanted to try. I alternate. I honestly think I like the cream better. Always use moisturizer then tretinoin then moisturizer

[@21972012145525]

@@fallenangelz291 she uses sandwich method to minimize irritation. I’m asking why is she using retin a and tret. They’re basically the same...

[@21972012145525]

@@RVC0902 interesting. Are the strengths the same?

[@Applepie409]

Really enjoyed this video. Thank you.

[@TexasTornado19]

I wonder why they would discontinue a product that had such promising results? They spent a lot of money to test it, just to discontinue it. 🤷‍♀️I would’ve bought it, if I could find it.

[@pajamamama5965]

Great video! For three years I tried all different Brands and strengths of otc retinols. I kept having issues with them and then taking breaks. My skin just did not like retinol. It would burn and be irritated and get rashy and red and no matter what I tried, my skin never adjusted. Adapalene worked well but didn't completely get rid of my adult acne. I used it for a long time until I could finally afford Retin-A. I didn't think I was going to be able to do Retin-A because I couldn't do retinol but ironically retin-a is the best thing that happened to my face. It completely cleared up the acne and after 6 months I started seeing what they mean about anti-aging with reducing fine lines and wrinkles and just looking more plump and less saggy. I'm glad I stuck with it because I started out only being able to use the tret once a week and then work my way up until now I can use it three times a week. It's really nice because it made my skin less oily like I can't believe at age 45.

[@courtneyjackson4843]

This happened to me too - couldn't tolerate Retinol on my neck but Tretinoin is just fine.

[@21972012145525]

What strength on your neck?

[@pajamamama5965]

@@21972012145525 .025 %

[@rebecca3745]

Off topic…..Dr. Dray, Coolibar Foraker UV Protection Sleeves UPF 50+ Sized XS on sale for less than half price (now $12.99) on their website. I thought you and other XS folks would be interested! I haven’t discovered a brand with better quality and style for sun protection clothing, but they aren’t always in my price range. Thanks so much for being such a reliable source for taking better care of ourselves!

[@dcmenchavez]

You’re looking better over the years Dr. Dray! 👏🏼

[@greyeyesntyler]

I use skincetuicals retinol 1.0 strength its $92 but my skin is looking great! It has really reduced my fine lines and skin cetuicals also has lots of test done on their products.

[@arborside242]

Thank you so much for this data. I was debating whether to schedule a dermatologist visit for my anti-aging concerns and just found out that my insurance does not cover Retin-A. This is perfect timing! I’m going to try Skin Médica. Thanks again.

[@cok580]

Adapalene vs SkinMedica vs Tretenoin for mature, non-acne prone skin? My skin is very tolerant of the Adapalene.

[@deedee2218]

Do you use Adapalene all over the face and under the eyes? Or certain areas only?

[@cok580]

I use all over my face but avoid the area inside the eye socket bone, not because of dryness, etc. but because I don’t want to take the chance of the adapalene migrating into my eyes.

[@honeybadgernasty]

Adapalene made my pores look huge! Do you see the same?

[@livethroughthis3863]

I’ve been using this for years it’s my holy grail 5.0 skin medics baby!!!✨💖

[@slavic101]

Thank you for reviewing this study Dr Dray! 💙💛

[@Rositasparks]

Great information and insight. The peeling from tretinion has always turned me off but I understand the benefits. I sold Skin Medica when I worked in skin health, at a plastic surgeons office . Thank you Dr Dray.

[@DrDrayzday]

thanks for watching

[@SA-ix6nm]

Apply moisturizer first then Tretinoin, you won’t get peeling. If u have very dry skin , apply another layer of moisturizer after the Tretinoin. So one layer before and one after the Tretinoin

[@meanreversion1083]

@@SA-ix6nm do you know if tretinoin can be applied to the whole face or only locally?

[@70sladyalways25]

@@SA-ix6nm yes, this is what I have to do. Since I started doing it this way, I have not had the peeling.

[@mtngrl5859]

@@SA-ix6nm I use this buffering method with my PC 2% Bakuchiol + .3% Retinol, I;ve had very good results. I always get PC with 20% off, so 1 bottle is like $42 and last around 4 months, much less expensive that tret.

[@RoseMary-gl4ee]

Thank you for this precise articúlate expose of the product and study.

[@RM-ud9tf]

Thanks, Doc! Great video, with fascinating facts! Have a good one, and see ya tomorrow

[@heathermunoz6282]

Wow a lot of info. My head is overwhelmed.

[@brittanykelly1261]

I love Skin Medica retinol! I’ve been using it for 2-3 years and have seen a big difference in my skin. I started with the 0.5 and now am up to 1.0. I’ve never experienced irritation, just a tiny bit of dryness in the beginning.

[@seasonedreactions]

What is your skin type?

[@LisaDunahoe]

I have been looking for a new Retinol product. I used the prescription from about the ages 11- 55. The one ingredient in the prescription that I believe caused me to have acne on my face which was Isopropyl myristate. I began using it for acne in the mid 70s. It did make me look younger but acne still plagued me for all those year. Right now I have using a product from a pharmacy but needed something stronger to combat wrinkles at age 61. I ordered the product you recommended. Thank you!

[@Realtor365]

Thank you for this Dr Dray! A cosmetic surgeon recommended Skinmedica to me about 3 years ago and I love it!!

[@ilmanley]

This type of videos is the reason I come to your channel over others. The content is informative and without bias. Thank you!

[@courtneys7522]

Interesting! I was using Skinmedica retinol .50 and felt I had pretty good results. Then asked my derm for tretinoin because it is the “gold standard”. I’ve only been on tretinoin a month but so far feel the skinmedica retinol was better for me. Will give the tretinoin more time but may switch back to the retinol.

[@pamcanfield255]

It's important to give it time! At first I felt the same, but it has really made a difference in my 68 y/o skin! The texture is so smooth. I get compliments every day!

[@Heallove24]

This is one, if not the only, Retinol that I have tried that actually works better than RetinA with minimal irritation! So glad that I tried it. I'm sold.

[@jkc8407]

I started tretinoin 0.01 gel a month ago. I absolutely love it! I haven't had any adverse reactions other than some drying on my chin. I use drunk elephant protini moisturizer on top, then add a sleep mask to lock it in. I also use face oils on top of my sleep mask lol. I'm 38 and I'm so glad I added tretinoin to my skincare. I also get monthly facials which may have helped prepare my skin for harsher products.

[@cathyray3861]

Thank you for all of your knowledgeable and trustworthy informations

[@nathaliez9783]

Hi, interesting study, but I will stick to retin A, I have been using the 1,1% strength for 5 years, and I do get occasional irritation, especially in our cold canadien winters, but I can’t imagine not using it..unless something better comes along..

[@redchile2060]

Nice study review, Dr. Dray. I always enjoy your content!

[@mielhoney]

LOVED this video! Fascinating information regarding the study results!

[@marylawman8603]

Appreciate the interesting lesson today. Happy Wednesday, Dr Dray! Hope you have a beautiful evening. ❤

[@reyramos538]

You are so knowledgeable 😌 Happy Wednesday Dr. Dray!

[@meggieprice]

Interesting results! I use Agency tretinoin but I mix it with my moisturizer to avoid flaking and peeling.

[@rosemarysemprez1265]

I began with Agency at the lowest level and thankfully had no redness and flaking on my rosacea skin. Gradually increased in three month increments. I also recommend using a emollient moisturizer to lessen 😢any reactions

[@meggieprice]

@@rosemarysemprez1265 I did have some flaking at first but now am good- and about to up my %. I really like their product- sounds like it is working for you too!

[@dawnphillips9386]

I haven’t watched one of you videos in a couple of weeks! Wow! I think you completion look great today!

[@laurenkeshet266]

I’m on skin ceuticals 1 percent. I use it 4 days a week. It really works !! I just a rx for .05 tretinoin i will probably start that in the fall !!!!

[@alexandramuchnik2906]

Thanks so much for very educational video Dr. Dray. I just google for the product and it looks like it was discontinued.

[@juliabinford6500]

Ever since you mentioned the advanced clinical retinol cream for the body, I’ve been using it on arms and legs regularly for a year, and it has improved texture of my body skin, though not as dramatically as tretanoin on my face. I think it’s probably a very low concentration. Of course, sun protection before and since starting the retinol. I hope it suppresses pre cancer cells.

[@johannaaguirre8263]

Would you be kind enough to share what product you use?

[@21972012145525]

She wrote them in her comment

[@samanthastorm9953]

You look great. I’m definitely taking your advice.

[@odettemarillier1297]

Got to love Dr. Dre 😍 Nobody gives it to us with more science and more layman term like her ... Keep shining 🤩

[@ericflorentino6952]

thank you so much for discussing this! i'll stick to my buffered retinols, then. I no longer need nor desire to FOMO over tretinoin. PS: US$96 for 1fl oz of a buffered 1% retinol is insane.

[@leeannlowery5064]

I appreciate the information on the study. My question concerns the strength of tretinoin that was tested. I understand the tretinoin was .02%. Aren’t most tretinoin prescriptions written for .05-.1%? Perhaps they chose the lower strength because they were comparing it to an OTC retinols. Thank you for your honest and educational videos!

[@riavanvliet799]

I think your a little confused. The retinol was .02%. You cannot get tretinoin for more than 1% which is what I use.

[@riavanvliet799]

and the lowest tretinoin you can get is 0.25%.

[@katgirlblue]

@@riavanvliet799 no, she said the tretinoin was .02%.

[@PassionPno]

@@riavanvliet799 No, you can get it in 0.01% in my country.

[@kristengvan]

@@riavanvliet799 no, OP is correct: kzbin.info/www/bejne/eaKngKlqmdWgaKc

[@fionatill5072]

Boots (UK) have just brought out a 1 percent retinol version of their 0.3 percent product that you reviewed previously so I was really interested to hear about this study. I have only just started using it so can’t comment yet on its effectiveness. They have also brought out an accompanying retinol soother to help to combat the redness and dryness.

[@galaxia4709]

Thank you for sharing the results of this study! Also, I wanted to add that you are looking so good, and the red color suits you so well! Bye!

[@browneyedgirl4637]

I bought this just now. I am 45 and I am told by many I look much younger but I am constantly looking for new items to try. I thank you for your info and hope this is a good product.

[@The_Black_Anarchist]

I had to purposefully irritate my skin so I could get razor bumps in order to get full strength tretinoin. I will be using the tretinoin for wrinkles under my eyes. It's a shame that medication is not sold in the free-market. We shouldn't need prescriptions especially when it comes to topical products.

[@justjen7183]

I use skinmedica’s highest strength. Using it for over 6 yrs. Worked wonders on my acne and pigmentation.

[@SpartaWarriorCodeRed]

Your skin looks amazing. Love your look on video. Your skin screams I’m healthy!

[@Brenda-jf2pe]

Your skin looks really good👍🏼

[@PenguinDownload]

Interesting that according to retailers online, that skinmedica product (tri retinol complex) has been DISCONTINUED. So at the end of the day we still don't have an OTC retinol that has proven anti aging benefits + their products also contain niacinamide, peptides, vitamin C and E and other antioxidants that could have contributed to the anti aging effect.

[@Marasma101]

Retinaldehyde….

[@dydb]

Cerave has a retinol resurfacing serum it’s over the counter and it’s very good

[@sup8668]

I just searched it up, I’m still finding many retailers that sell it.

[@21972012145525]

What about the actual product t? What are the other ingredients?

[@homeswethome]

The question is why they discontinued it. It seems to me that this companies are just trying to make a buck of something that can be dangerous at the end. There's no fountain of youth sadly and will never be.

[@Samson373]

Great video. The SkinMedica bottle depicted at minute 12:22 is the Tri-Retinol Complex ES but the product bottle shown just below the video chapters is the Retinol Complex 1.0. I suspect the study used the latter product. Anyone know for sure? Thanks! [Can only find the paper's abstract available for free online. However, the clinical trial summary refers to 1% retinol cream which sounds more like Retinol Complex 1.0 than the other one.]

[@marymckenna5524]

You had me at skin biopsies! Sadly, my super sensitive facial skin does not play nice with any of the retinols I have tried. I switched to the Avene retinaldehyde 0.1% and trained my skin over a 5 month period starting at once a week and very gradually increasing frequency to nightly. I did not experience redness, peeling, stinging or hotness during or after the 5 month introduction period. So I have my Vitamin A skin product and am not likely to experiment further.

[@ilmanley]

Isn’t retinaldehyde stronger than retinol?

[@ilmanley]

I mean it is one step closer to tretnoin then retinol

[@marymckenna5524]

@@ilmanley Yep! Maybe my skin hates two changes instead of one? Or just maybe I was too impatient when trying retinols earlier! ;)

[@denisenj7648]

I use curology .14% tretinoin for 40 bucks every 2 months. Yes, stronger than the strongest of .1%. It also has 5% azelaic acid and 4% niacinamide. I think it's a great deal. Been using it for years.

[@marycolling4544]

Great info thank you so much for educating me for free ♥️

[@dangerbuoy]

Thanks, really helpful breakdown of the study!

[@deborahpickerill2772]

Fabulous content, as usual.

[@perth881]

Happy Wednesday!

[@nadab4750]

👱‍♀️❤

[@DrDrayzday]

Same to you

[@kara6767]

Hi doc! Is this better than Avene Retrinal 1.0? Thank you

[@danielegagnon7920]

Happy Wednesday! Love this subject!

[@nadab4750]

👱‍♀️❤

[@21972012145525]

Oh no dr dray misplaces comment!

[@danielegagnon7920]

I am still receiving fraudulent messages. I report them is all I can do. They changed their message! I'm going to go change my password for KZbin!

[@21972012145525]

@@danielegagnon7920 I don’t think you need to. Just report and dont engage

[@afg1874]

Great video. I am forever grateful for you, your channel, and the information you provide. I recommend you every chance I get. I've been to many dermatologists throughout the years and not one was able to help with the multitude of issues I was experiencing. Following your videos and advice, my rosacea, acne, and dry patches are all controlled. My face looks and feels so much better and I have you to thank for it. So again thank you Dr. Dray you are truly a blessing.

[@galaxia4709]

How did you control rosacea? Thanks!

[@honeybadgernasty]

I second that!

[@cametientaucoeur]

Please share what products that you use to control your Rosacea that were recommended.? I would really appreciate it. I just tried an expensive LED light which seemed to make rosacea much worse? Jeanne retired RN

[@honeybadgernasty]

@@cametientaucoeur have you tried azalaic acid? Or a V beam laser?

[@galaxia4709]

@@cametientaucoeur I've read online that primrose oil has helped people. But I'm still wondering what helped the original replier. An acid does seem contra-indicated to me.

[@oceanbird.]

I have very sensitive skin with rosacea and my dermatologist recommended the skinmedica 0.25% retinol because I really wanted to try some kind of retinol for anti aging. And all the OTC products I tried previously irritated me a bunch. I got up to using it twice a week and it never caused any irritation. I always notice the next day my skin looks bright and bouncy, but I haven't noticed any changes in dark marks, and don't have noticeable wrinkles yet. I also use medik8 bakuchiol serum every day and I love it!

[@kyliessave8454]

Dr dray did you see that viral tiktok video about the patch that let's you know when to reapply sunscreen 😆

[@db-gb5xi]

Scott Walter MD (a derm) did a test with one. He's got a short on it.

[@kyliessave8454]

@@db-gb5xi oooh thanks!

[@alliebri25]

Thank you thank you thank you! Bringing up the skin of color portion is so nice to be aware of. I spend thousands of dollars with medical skincare offices, derms and over the counter and I'm so worried about professionals not knowing all the risk when putting stuff on my skin

[@karlaorourke7554]

Excellent video Dr. Dray, great information to know.

[@aeducator1]

Thank you to Dr. Dray for pointing out this study. There is something really weird about it. Something we have never seen before with a clinical study. The actual study was done more than 10 years ago and they only decided to publish it now. That weirdness is underlined by the fact that several well known academics on the publication are funded by SkinMedica.

[@eee3400]

it struck me as fishy that the chosen tretinoin concentration was low on the scale of available concentrations. more useful would be a follow-up comparison that uses the .1% tretinoin.

[@liabilitylinda3501]

​@@eee3400 to be fair the strength of tretinoin used in anti-aging studies is 0,05% so that would be an ideal concentration for comparison

[@sunseeker65]

Thank you for freely sharing your expertise in skin care. It makes me feel much more confident in purchasing and using products that you discuss.

[@judycarter2010]

Hi Dr. Dray, Thank you for your videos and skin care advice. You've had a tremendous impact on my product choices and skin care routines. In fact, just bought the SkinMedica retinol complex. I'm 72, and I think my facial skin is fairly good and young looking, considering my age. However, I'm developing marionette lines and I truly dislike them. Would you address the issue of marionette lines and any safe and effective treatments that improve their appearance.

[@langyd4518]

really the only thing you can do for marionette lines other than Botox is to not sleep on your face and to start a retin a retin a regimine as soon as possible like in your mid thirties. massage upward gently when applying your creams to the marionette area. Other than surgery there isn’t much you can do. I have heard of some devices that are supposed to help but I have never tried these. possibly the right device plus use of retin a and definitely don’t sleep on the side of the face would be your best bet unless you can pay for surgery

[@marianne6373]

Looking at Skinmedica prices (holy moly!), I think I’ll stick to my tretinoin prescription. Here it costs more like $200 +++

[@DrDrayzday]

it is $96 on dermstore, an authorized distributor

[@susanmcf1]

Very interesting and helpful.

[@shannonrodriguez8165]

Really looking forward to your thoughts on skin better alpha ret. It’s been on my radar for a while.

[@elena-it7xs]

She recently made a video on Skinbetter Alpharet

[@mariaburger8774]

That's interesting! Thanks

[@DrDrayzday]

thanks for watching