The Truth About PGT-A TESTING

[@lexxxxxxxxxxxxx]

No benefit for younger women to have PGT-A? At 25 years old, I have four losses and three years of infertility under my belt. 17 eggs retrieved, 9 mature, 6 fertilized, 3 made it to blast, 1 euploid embryo. Despite the shock of my IVF doctor, I’m so grateful to have done PGT-A as a young patient. My other two embryos had Turner’s syndrome and trisomy 7, so PGT-A saved me the heartache of two more losses.

[@priscillarose18]

My husband has a balanced translocation. So in this case, I would say it’s 100% necessary as the risk of recurrent pregnancy loss is very high. 4 out of 6 blastocysts were unbalanced and would not be compatible with life.

[@freespeech.7254]

What is balanced translocation😮

[@priscillarose18]

It’s a lot to explain lol basically 2 chromosomes switch places all genetic material is there it’s just two segments broke off and switched. It causes or can cause miscarriages. It’s a coin toss if a pregnancy is viable or not. And the baby can be born a carrier of it or not have the translocation at all. My husband’s dad has it too and now my son does, as well. About 1 in 500-1000 have it. And some translocations depending on the chromosomes involved can be compatible with life and the person is then unbalanced and can have all sorts of health problems. Meaning instead of the chromosomes switching places one chromosomes gains an extra segment and the other chromosomes loses genetic material. The one my husband has causes early miscarriages if the baby is unbalanced.

[@freespeech.7254]

@@priscillarose18 glad you had a son. Its a gamble but in the end you are a mom❤️

[@priscillarose18]

@@freespeech.7254Yes, thank you! I actually just had my 2nd son almost 3 months ago and that one was natural. 🤍

[@freespeech.7254]

Crazy what internet does to you. Some say testing is good and some say not good🙄🤦‍♂️🤷

[@DrVictory]

It’s absurdly still controversial. These days we recommend it for those over 35. Things are changing but there is still no good trial.

[@ZanetkaPL]

Is there value in doing PGTA testing for a 30 year old couple with unexplained recurrent loss (4 losses) ?

[@senorasolitaria7908]

If your genetic compatibility screening is normal and your cavity is normal, then pgt is a good choice. If you find a clinic that offers pgt included in the ivf package, you won't need to pay extra

[@litan9002]

Thanks for sharing the info.

[@saritaelqady]

thank you for sharing

[@sandrazafirova9627]

Hi. I have a robertsonian balanced translocation 13, 14. I had no issues with conception, from the first try i got pregnant. Unfortunately it ended up with down syndrome and me and my husband decided to go for abortion. My question is should i try naturally again, or should i go IVF with PGT? What are the chances of having a healthy baby if i choose to go the natural way?

[@sammi0816]

Hello, I just turned 39, I got only one frozen embryo, PGT was done and came “inconclusive test” and they asked me if I want to re-biopsed. They told me embryo is 6bb which they said is very good news. Do you consider is worth it to transfer without re-biopsy and give it a try? They are asking me to do second round but I’m looking to have one child. Thank you

[@senorasolitaria7908]

6bb is great. It's already hatching. I'd transfer. Rebiopsy means tgaw, biopsy, refreeze, wait, then rethaw when ready to do the fet. Too much stress on the embryo

[@sammi0816]

@@senorasolitaria7908 thank you for your reply, I decided to transfer and I got pregnant. Unfortunately I miscarried two weeks ago at 8 weeks 😞

[@ogeanazia3230]

so sorry to hear this@@sammi0816

[@lah1667]

Sorry :-(

[@sammi0816]

@@lah1667 🙏 thank you, it’s been a journey for me. Haven’t had any success yet but I’m still fighting.

[@cjoele]

I'm 38 years old and I am using sperm from a donnor ( good quality) I've had no perticular issues with the initial testing the fertility center had me go through. I'm wondering should I spend the money or is it just because for the money that they strongly suggested that I get PGTA testing. I live un Quebec and the government pay for one IVF cycle

[@tracy3418]

What about over 35 with endometriosis?

[@Itz_urfavcharlotte]

what about Male Factor ???

[@mandyz7032]

I only have 2 embryo should I still go PGT-A testing ?

[@zhang876]

thanks for telling the truth!!!

[@CocoBookClub]

Hello Dr, what do you think about Mosaic embryo transfer? is it okay to do the transfer? what's the percentage chances to result in healthy pregnancy? Thanks

[@renatarusso7930]

Good information. But you said that you think it’s good to do test for older patients, after 40. But since most of older patients doesn’t make to much embryos if you discarded any the good ones by mistake it isn’t even worse. I understand if you are doing back to back cycles to get good ones. But not everyone can afford time and money for that. Also for what I see and even understand that you and others people said that the test could also been harmful with maybe less embryos making to blast.

[@dwightshowman]

Perhaps the criteria for use then, should be patients who have a higher than normal risk of miscarriage (for example patients over 40) BUT who also product large numbers of embryos in IVF (which will be a smaller subset of >40 patients, but still do exist)? For older patients with lower embryo numbers, the margin for error with PGS is too high a price to pay. For younger , good prognosis patients, there's also no point, as they're going to succeed without it and with a low miscarriage rate anyway.

[@saras7358]

Thanks for sharing! Which clinic is it in toronto that forces people to do PGT-A?? Is it markham fertility clinic?

[@onlinecakemie]

Thank you for sharing