Ezetimibe Explained: Uses and Side Effects.

[@doeidaho2101]

Thank you so much, once again for your dedication and information. Your calmness in presenting the information is enlightening since many people ramble on & repeat themselves while forcing their opinion down your throat. You are a real professional.

[@germael1]

why do you take so long to get to the the POINT? Click the bottom, and here we go again. GET RTO THE POINT.

[@alinkilpatrick9302]

I love your disclaimer. Just love it. Perfect and appropriate. This information was helpful

[@HPLeft]

I used to be on this back in the day but got off the moment that I read the results of a study suggesting that while Zetia lowered cholesterol numbers, it did not lead to either a decrease or even stabilization of any sort in the thickness of plaque in the arteries. I had been taking this instead of a statin - but then switched instead to Zocor (and have now been on Atorvastatin for the past decade). I now start my day instead with serrapeptase, which has a reputation for dissolving inorganic substances - in the hope that it will reduce plaque. I also take a concentrated high-dose fish oil supplement - but the dosage is nowhere close to that of the new prescription drug whose trial you reported on the other day. My POV is that if a Zetia-like drug is either not reducing the level of plaque or taming the inflammation within the body, there's no reason to take it.

[@Joe-mz6dc]

Atorvastatin gave me muscle aches, bruising, pain and fatigue. No problems with Ezetimibe.

[@LK-bz9sk]

@@Joe-mz6dc did the Ezetimibe help lower LDL etc? I am also very intolerant of statins. Thanks

[@SongbirdRanch2005]

SETI’s only blocks dietary cholesterol. If you are like me, my cholesterol is mainly from my own body’s cholesterol production, I don’t see much help on me.

[@bunjicarlin1]

THANK YOU!

[@wguan5885]

I’m a hyperabsorber. Ezetimibe itself without a statin halved my LDL. Miracle drug for me. By the way, 5 and 10mg are pretty much equally effective for hyperabsorbers.

[@Jupiter_Crash]

Thxs for that. I can’t tolerate 10 mg so I’m currently in a wash-out period and will restart @5mg. I’m a hyper absorber too.

[@wguan5885]

@@Jupiter_Crash what happened to you with 10mg? Elevated liver enzymes?

[@wguan5885]

@@Jupiter_Crash if you look at the Phase II trial data dosed at 0.25, 1, 5, and 10mg. 10mg is like 18% lower and 1mg is ~12.5%. But you cannot find 1mg ezetimibe on the market.

[@Jupiter_Crash]

@@wguan5885 - I haven’t had my liver enzymes tested yet. I think once I restart and am on 5 mg for ~4 weeks my doctor will test them. Ezetimibe reduced my LDL by ~33%.

[@Jupiter_Crash]

@@wguan5885 - the muscle aches were too much with ezetimibe and then a low dose statin was added and I realized I can’t live like this. Adding the statin restricted my jaw’s range of motion and my Achilles tendons started to ache. If the restart doesn’t work then my doctor wants to try Repatha.

[@bryanm1498]

I have been doing my own research on statin and cholesterol studies performed during the past 10 years or so and that were not industry funded. There are numerous studies indicating that LDL is not the culprit for CVD and therefore, statins do not treat the cause of this disease. I got off Atorvastatin but remain on Zetia and am on the fence about whether to continue it as well. I wish I could see a debate between a couple of cardiologists regarding whether LDL is the main factor in CVD or whether we are treating CVD incorrectly for all these years. And, I do not want to hear from big pharma or their many sponsored studies on the subject as they clearly have incentives to ensure as many people as possible are put on statins. I just want the truth and it is hard to find. Thanks for the video as I remain open minded on the subject and you shared some good info.

[@guardrover]

So what's the alternate solution to CVD?

[@bryanm1498]

@@guardrover I wish I knew. I am kind of at an impasse. I do know that while on a high dose statin my A1C went into prediabetic range despite a good diet and a great deal of exercise. After being off the statin my level is back to normal. That's what started me down this rabbit hole when I found out that a potential side effect of statins is diabetes. That's nothing to mess with! Hopefully we will get the truth some day but I don't see it happening anytime soon.

[@abukalen]

Check your ApoB level. That measures the number of atherogenic particles, whereas LDL is an indirect, calculated measure of volume - not particles.

[@hdodgers4487]

Did Atorvastatin damage your liver ? Or did you experience pain on your legs ?

[@bryanm1498]

@@hdodgers4487 No, fortunately I did not experience either of those - other than occasional leg cramps. However, I did have a sever bout of acute pancreatitus which the hospital believed was due to my Zetia statin and advised me to stop taking it. I am no longer on Atorcistatin or Zetia and am on a lower dose alternative.

[@joeordinary209]

I am having rosuvastatin 5 mg + ezetimibe 10 mg to stabilize soft plaque. Cholesterol is pretty ok(5,1mmol/L). Considering reducing to every second day only.

[@MountainRaven1960]

I’m only watching this in order to learn how to pronounce Ezetimibe.

[@katherinesica3215]

LMAO!!

[@greegan37]

@@katherinesica3215 You'll be unable to pronounce it correctly if you have a heart attack.😊😊

[@LK-bz9sk]

I am very statin intolerant. Have high LDL and some CA buildup. My dad had a stent but at 85 years old. I have normal blood pressure and no diabetes and work out a lot. To include cardio. My doc seems to pay very little attention to the latter 3. Trying the ezetimibe starting this week

[@psoneill813]

Let us know how it goes. I was intolerant to statins and was just prescribed this due to high cholesterol. I am uncertain if I will take it. I radically changed my eating and excercise daily.

[@Rapscallion2009]

I think Doctors are now trying Ezetimibe if statins are not tolerated. What I'd like to know is whether there's any reason to believe that they'll tolerate one cholesterol lowering drug better than another.

[@katherinesica3215]

I started taking this. I felt horrible. I use Trelegy and it stopped working when I started using this stuff. I was weak, tired with muscle aches. I thought I had Covid! Took a test. No Covid. It never dawned on me that it could be this medication. I decided to stop taking it and to my amazement over night, my symptoms were gone.

[@ceciliabelgica2023]

thanks for sharing...I feel crap and the doc will not take me off these poisonous drusg

[@mary-elizabethcoetzee685]

I almost died from it. I got all the side effects.

[@mathewfinn5725]

Thank you for this Doc. Being on HRT sometimes my lipid profile goes out of sync. I use red yeast rice. I know statins are very bad for you in the long run. I am 41 years old. How does Ezetimbe compare to Statins?

[@Joncartervoiceovers]

How is red yeast rice working for you?

[@joelronne2721]

Red rice is just a natural form of statin so chances are that it has the same long term effects as prescription statins.

[@ankitms14]

Tried Statin for years, didn’t work for me. Having too much muscle aches and bodyaches, worst of all I had a feeling in my chest like a thread was going through my heart all day, it was painful. Been on Zetia and it’s definitely have been very bad for me, I started have anxiety / Panic Attacks daily. I can’t workout I don’t feel mentally stable, I feel like I’m dying. Been on it for 3 weeks now… and it’s been happening every day now.

[@bayareamacaddict]

Yeah. Ezetimibe also made me have anxiety and panic attacks 😢

[@markthurlow6223]

I’m having anxiety and panic as well…

[@ankitms14]

Update, after seeing cardiologist, I got prescribed Reptha injection. It so much better. No side effects… discomfort in the injection source but definitely worth it. I take it once every 2 weeks

[@ceciliabelgica2023]

thanks for sharing...I have been on this for a couple of years, I supplicate my doc to take me off drugs as I still feel so crappy far worse than before the heart attack, main artery plugged 100% the other 75 %, 3 stents put in so I should be better?...nop I can barely do more than30 min walk, I used to do 2-3 hours and weight lifting 30 min, and biking rowing another 30 minutes, now arteries are opened and I feel crappy...go figure!

[@mary-elizabethcoetzee685]

Those pills almost killed me. I dont know how they can be on the market. I truly almost died.

[@socalifone3044]

So how did this medication almost kill you?

[@gabrielgabriel8908]

Quick question doctor, statin really affected my liver enzymes by making them too high. Does Ezetimibe affect the liver as well? Please let me know

[@psoneill813]

Same for me.

[@RavenWolfDrum69]

Why did my dr put me on zetia and another pill ezetamibe plus rapatha replacing ravuvestatin

[@MrVWQ]

currently on 80mg of Atorvastatin still using it and my PA in cardiology is now giving me this drug (10mg) as well? Wondering if thats normal to take both at the same time? Or should the Statin be removed if on this drug?

[@Jupiter_Crash]

From my understanding adding the ezetimibe to your statin is standard protocol if your numbers are aren’t on target.

[@kimneek6813]

Hello, I have been taking this medication for about three weeks now I have noticed some diarrhea. I also have had a few a fib situations since I’ve been on this medication. Is this medication something that would harm me if I was to go off of it or do I need to be winged off of it

[@desperadobakorpakem]

Hii doc, currently my LDL is 170, trygliseride over 220. So my doctor prescript me a rosuvastatin 20mg and ezetimebe 10mg for a month.

[@Eric-kz9bk]

Is this similar to plant sterols? I’ve seen these supplements like “cholestoff” saying they work thru plant sterols inhibiting dietary cholesterol absorption.

[@bonniebradley6461]

This is what my Dr gave me. I have terrible pain in my arms and hips. He doesn't think this is true.

[@christinashawgo6510]

I developed a odd rash with crestor, my doc wouldn’t believe me either.

[@katherinesica3215]

This crap made my Trelegy stop working. My muscles hurt. I was tired. I took myself off it.

[@revmiguel2000]

Fire your doctor

[@AndyB718]

My Cardiologist orefers my LDL to be 50 or lower. Both parents had open heart surgery and i got a little of both genetics wise.

[@guardrover]

For CVD regression, the LDL needs to be lower than 70. Your doctor might be right. Also omega 6 helps

[@locutusofborg7122]

Dr. Ritter, as I have mentioned previously in another post, I had a rather mild heart attack a little over 4 years ago --- at 53 --- but still had to have a triple CABG. About 3 months ago my cardiologist added 10 mg Ezetimibe to the 40 mg Rosuvastatin I had been taking since the CABG. Initially, after having my CABG, he said: "Ideally I would like your LDL to be 70, but I'll take 100 or less." Heretofore, I have been only on Rosuvastatin these 4 + years. My last blood test showed LDL to be 96. I see him again in March, so I am going to ask him why he changed his mind on the "100 or less LDL" and added Ezetimibe. I suspect it is because I recently was told I had a "change" in my ST, so I surmise that may be why Ezetimibe was and added. As concerns myself, I have not noticed ANY side effects with Rosuvastatin or Ezetimibe.

[@CardioGauge]

The Guidelines got rewritten about a year and a half ago, and they (the Cardiology Trade Organizations) changed the recommendation for people in your shoes to include ezetimibe to try to get LDL under 70, whereas prior to that, the guidelines just said do rosuvastatin 20 or 40 or atorvastatin 40 or 80. I doubt it has anything to do with the ST segment.

[@locutusofborg7122]

@@CardioGauge Well, I must admit you busted me Dr. Ritter. Although I see my GP every 3 months for blood work, I had procrastinated seeing my cardiologist for about a year and a half until recently. Your reply perfectly illustrates why one should not do what I done; but at least now I am back on track and will no longer procrastinate.

[@caleblauber1441]

I always wondered about how to use Zetia correctly.

[@dmg12345678]

I need to get my hdl higher currently 32-35 with 10mgs lipiitor daily, should i add zetia? No previous heart issues. Ldl is around 70. Would 20mgs mgs of lipitor raise my hdl to higher levels? Thanks.

[@CardioGauge]

Hi Dmg12345678, zetia and increase of Lipitor would likely leave you HDL around where it is. Mediterranean Diet is good for boosting HDL, and 1 alcoholic drink per day can increase it. Routine exercise helps a smidge with HDL. Having A small handful of walnuts or Brazil nuts daily can help. In general, I don’t recommend medications or supplements with the purpose of increasing HDL. Best wishes!

[@saltburner2]

I am allergic to all statins and was prescribed this, but it is unavailable in the UK as the NHS is unwilling to pay for it. Statins work for about 98% of those who need them, but those who are allergic to all statins - like me - cannot get it, Any suggestions? My GP suggests getting it from France or another European country - I have contacts in Germany and Austria - Is this a practical solution?

[@billakis2000]

Had no problem getting it in London

[@georgetsiobanos5936]

After a stent my HDL is 86 my LDL is 79 is it safe

[@dmg12345678]

HDL is great at 86! If possible try to get and LDL between 50-65, below 70 would be ideal. 10-20mgs of Lipitor day would definitely lower your LDL to that range if u are not already on it.

[@nomore9203]

Can Ezetimibe cause Dizziness ?

[@hdodgers4487]

I read that it causes dementia so am scared of using this pill

[@yvonnepompey4200]

That medication almost sent me to the hospital I had excruciating muscle pain from my butt all the down to my feet I had only taken 4 pills

[@guardrover]

There are alternates like Bempedoic acid if one is allergic to statins

[@hdodgers4487]

Is there an organic pill that can do the same job ??

[@MilanMazic-p9l]

Fiber and, PCSK9 Inhibitors.

[@tenniskinsella7768]

Can this tablet cause dementiza

[@jeffreykilpatrick3592]

What about repartha -- ? And zetia?

[@sugarcan1110]

On this drug ezembibe Triglycerides 7.7 in December 21 February 22, 3.4 level Told doctor didn't want statin so put me on valsartan 80mg..been on 4 months ..bp down to 110 will go back in may ..need to get off these drugs hope I get off them by august or before , 43 years old males put on weight 106kg guess I'm a success on this drug in a short space of time still averaging 106kg

[@ceciliabelgica2023]

I want off all these drugs, I feel crappy on them..how have you progressed?

[@donbrown7694]

Thanks for the frank option that its positive effects are not well proven

[@kl0wnkiller912]

I take it with Repatha. I cannot take statins as it paralyzes my heart muscle (yeah). My LDL is around 40. I had a heart attack in 2015. As of the last test my heart was healthy and no signs of blockage.

[@dr.brianjudedelimaphd743]

is it overall more effective than niacin ?

[@caleblauber1441]

Yeah... I’m wondering the same thing.

[@zsigzsag]

I've been taking Niacin with Omega fats daily. My diet is basically vegetarian but my LDL was still high but triglycerides were low.. I can't take statins causes severe muscle pain. Doc said my high LDL was probably genetic(?). Going to try the Zetia. Niacin has other benefits so does Omega fats so will still take thos. Will let you know.

[@alexciocca4451]

I take Crestor 20 mg cholesterol went down a little then added zetia my ldl went down 150 points about every 4 or 5 years I stop Crestor for a couple of months but keep zetia then I start Crestor again all being monitored by my doctor for 15 years

[@home8706]

had 3 stents fitted was statin intolerant so was put on rapatha great for numbers but side ffects chronic pain blisters etc so put on eztermibe plus a statin and blisters etc still there lots of pain and infections

[@georgen9755]

one in fifty people suffer from chronic constipation , coronary blockage , renal issues , frequent nocturinal ... 220 to a low of 100 cholesterol security administration gate ...

[@randyk7699]

I cant take statins. I have failed them all. Zetia is the only thing take!

[@caleblauber1441]

Did it improve your lipids?

[@preciousvalentinolagv2328]

Does it work ?

[@randall1959]

EDTA keeps my cholesterol below 100

[@ceciliabelgica2023]

wouah! How much do you take, what s your gender and your weight? where do you get EDTA? please do let me know I want off ALL the drugs

[@randall1959]

@@ceciliabelgica2023 I'm a 65 year old man that weighs 200 pounds. As for the brand I can't tell you because if I do this channel will delete my post.

[@brucemortensen4554]

Its a horrible medication prescribed to me by my doctor. Severe intestinal issues including the worst stomach cramps ive ever had. I stopped taking it and side effects ended. I read up on it and cant understand how it was ever approved. Read up on their initial trial called "Enhance" and the congressional investigation when this drug came out in 2007. It did nothing to reduce mortality. My doctor was unfamiliar with the side effects and the initial Enhance trial.

[@tonykiang9052]

Doc, don't mind me, u little out breath..pls take care, take a break? Thks

[@joechambers8603]

Statins are a Death sentence. All those people ridding in carts instead of pushing them are on statins I experienced statins myself. I exercised every day till I was put on statins. I got smart and through them out. Then I started exercising again. 'When you put your patients on stins you are starting their slow death sentence.Im now 81 exercising and taking Ezetimibe. My son used to go to the gymn 3 times a week. He was like those Guys on the Magazine covers. till they put him on the death meds, STATINS he quit exercising and eventually died. I could not get him to exercise or get a different doctor and SO HE IS NOW DEAD.

[@hilda-k4x]

Sorry for your loss.

[@Chiroman527]

Dr., myb LDLs have been consistently over 130-140 for years now. My HDLs used to be 60 or so, now they are 53, Total Cholesterol is 260 . I'm 70 YO, 5' 10' , 219 Lbs , bUt have not eaten Junk food for years. No Burgers, little red meat , more chicken, more fish, Lots of salad (Only Olive oil since I was a kid), Trig. are also elevated at 253. My PVP has been Pushing me for years to go on Statins. In 2016, I did start one (forgot which - mild dosage of 20mg) and in 3 days had severe Calf cramping. My Doctor prescribed Ezetimibe last year in 2020. I did Not take it .. Now I just got these new blood test numbers .... Now I will try it. Natural Stuff is NOT working . I take Flaxseed oil 1000gr everyday, together with many other supplements to help me deal with my many Spinal issues / Chronic pain with lots of body Inflammation (IBS, Sinusitis, Tinnitus, Spondyliosis , DDD, and dextroscoliosis. I also have a 50% calcification blockage in 1 artery detected in a Chest CT Scan a few years ago which was ordered for pulmonary condition (lung Granulomas). I did NOT tell my PCP that I didn't take the Ez. I will commence Today.

[@joyceelmer131]

Don’t eat refined grain,pasta, anything with sugar in it. Check labels. Even check salad dressings (they have the bad seed oils and sugar fresh whole unprocessed foods are the best. Increases good HDL and takes down triglycerides.

[@gloriachecastronyjjjbczujc7418]

Nesesitoenespañol

[@fredrik1337]

Also nesesito una spacebar 😂

[@locvu913]

I suspect this drug may cause lupus

[@nanettetredoux7613]

It gave me severe muscle cramps.

[@ceciliabelgica2023]

me too