Fasting and the Brain: The Latest Research With Dr. Valter Longo | Live Talk Being Patient

[@Psalm9one1]

I had great results on a high fat, moderate protein diet, very very low carbs. Turned into OMAD with hardly any problems going 23 hours 30 mins fasting time. I am going to try feasting and fasting. Thanks for these videos

[@petermacdonald6332]

You’re actually wrong. He is here to talk about his “Fasting mimicking diet” . There’s many benefits to all types of fasting.

[@maggiv5401]

What kind of results are you talking about? He’s not talking about weight loss. How long have you been doing it? In any case, we’re all basically eating a test diet. We won’t know the real results until we see how long we remain healthy. Lots of people are fine until they aren’t.

[@Sofia99988]

I made 20 important Italian dishes and published them, all recommended by Professor Valter Longo, thank Professor Valter Longo very much.

[@maggiv5401]

You published dishes?

[@marshabearman5594]

AWESOME QUESTIONS with really WONDERFUL ANSWERS!!~ Thank you!

[@markgoodwin183]

People who skip breakfast die younger? I would like to see that study.

[@cindilacasa3291]

Fantastic interview with a lot of great questions.

[@BeingPatientAlzheimers]

Thanks for the love!

[@leighburville2717]

I've been fasting for six weeks 20 hours a day. Drinking a 1/2 gallon of distilled water with 1/4 cup ACV and pink salt. I am just not hungry anymore. Not even at mealtime which is between 3 and 7 pm. I've given up sweets and starches except for fruit smoothies and sourdough bread. I feel good.

[@carlaalhinho9554]

What is AVC/

[@Bigcrazyt]

@@carlaalhinho9554 My guess, apple cider vinegar

[@honeywest]

@@carlaalhinho9554 34:20 apple cider vinegar

[@chrisferrario1540]

@@carlaalhinho9554apple cider vinegar

[@bellaboo6720]

​@@carlaalhinho9554ACV is apple cider vinegar

[@dhanawaken9323]

Dr Thomas Seyfried has it right!!!! 🙌🏼👍🏼

[@ryanbarroga7384]

I'm a stroke survivor and I wanted to join the clinical trials how can I join

[@Healthnut1976]

Fascinating! I'm also a Registered Dietitian, Vegetarian and 100% Italian descent.

[@susymay7831]

Timestamps would help your nice videos! 👍

[@michaelhussey440]

Skipping breakfast and a long overnight fast SHORTENS lifespan? !! 18.20 This is something I have never heard and if you Google the subject large numbers of sites say the opposite. If promoting longevity is Dr Longos mission why do so few people know this ?

[@maurice4407]

I heard that too? Weird he said that I hope he can clarify

[@eternalwarrior-yp2qx]

He sometimes gives conflicting statements. One time he says I don't believe ketosis is doing anything good and in another presentation of him, I caught him saying it's beneficial for the body and the brain etc. They're just trying to sell their "diet" that is not a sustainable diet anyways. It's money-oriented.

[@MrGeorgewf]

Because breakfast sets-up your fat burning mechanism. If you starve the body adjust and burns less fat. Starving is not sustainable.

[@maggiv5401]

@@eternalwarrior-yp2qx i’ve heard him speak about that in various context, but my understanding was that he said it’s not the way the body is meant to fuel itself all the time. Periodic ketosis is beneficial.

[@htttppppp]

How can you have low amino acids when they are a building blocks of protein?! This sounds nonsensical.... I think this is a confusing video.

[@DevanUniversity]

Excellent!

[@beverleycumming1876]

Water fasting is so much cheaper…Prolon is too expensive

[@svanteforsman8244]

You can do DIY fasting mimicking diet. It’s basically 400 kcal healthy fat sources like nuts, olives, avocado, olive oil and 400 kcal vegetables.

[@conisalgado1294]

Yes Valter was basically forced to create this by the university because the studies have to be funded somehow. Prolon is basically 800 calories of fatty plant products such as olive oil nuts avocado. The point is keeping fat high to induce ketosis but low calorie to basically be as close to a water fast as possible. The university told Valter you can’t sell a water fast basically and it may not be safe for cancer patients as water fasting means no calories coming in which could mean faster muscle waste or cachexia. But if you’re healthy yeah water is fine but water and electrolytes is even better and safer and still induces same amount of fasting benefits

[@annburge291]

Perhaps water isn't cheaper? Valter Longo mentioned in one conversation that when the gut microbiota does not find a food source they will start to break down the gut wall mucus layer making the gut more permeable to toxins, ulcers etc. Who wants a leaky gut? The whole idea of fasting mimicking diet was to find a way to achieve the success part of water fasting (no glucose or glutamine) without the potential downsides. One also wants to find a way that people could comply in their daily lives. Prolon is for those who want a structured do the thinking work for me and give it to me on a platter and so clinical trials have something to compare. It's cheaper for us that someone else does the clinical trials.

[@barbarafenton1775]

Just what I wanted to say...thank you!!!

[@ronaldgmaster5782]

Try doing a 5 day water fast. You won’t be able to.

[@tejasparikh6610]

Very nice information ,what is the difference between 5 day water fasting and 5 day fasting mimicking diet?

[@joannasheldon2146]

During the former you only drink water; during the latter you take in 700 to 800 calories a day of high-fat, high-fiber (from complex carbohydrates), low-protein, low-sugar food.

[@maggiv5401]

@@joannasheldon2146 I have done the diet many times and there is no way you can call it high fiber. It’s also actually not high fat because the calories from fat and carbohydrate are actually pretty close to each other in terms of their percentage.

[@maggiv5401]

The major difference is that in one of them you get to eat some food, but it is very precisely formulated so that it mimics what it is like for the body to water fast. There are mechanisms that turn on when the body does not sense that it’s getting, a certain amount of macro nutrients. His team was able to figure out how to deliver a certain percentage of macro nutrients, and calories so that the body interprets the same as if there were no calories coming in. It’s sold out there as a weight loss diet, but that it was never its intention. It might be a side effect for some people. I was already in my normal BMI range when I did many rounds of it spread out overtime. I was doing it for the metabolic benefits. I did lose some weight each time, but it would’ve taken a tremendous amount of effort for me to eat so that I didn’t gain any weight back and I wasn’t intent on that. I’ve participated online with groups who’ve done it and there are people who started off as obese and did many rounds and were able to keep weight off, but they had to change their eating overall a lot. I did it because they found that even if somebody did not eat really well, after doing many rounds, a lot of the benefit remained. I didn’t eat a junkie diet anyway having changed it years ago to take off middle-age gain of about 40 pounds, but because I was aging and because I had seen older members of my family have a fair number of metabolic problems, I decided to take matters into my own hands. Unfortunately, diabetes does run in my family, so I have to be a little more careful as I’m aging than I expected. But I think some of my problems have been created by not being consistently active. Longo doesn’t talk about that a lot but most of the people he studied, who were not genetically predisposed to longevitylead more active lives than we do.

[@joannasheldon2146]

Love this guy and have done his diet and understand the reasons for it, BUT recommending that we all eat fish as our sole source of animal protein is unrealistic. The oceans are already overfished, for one thing. For another, there is the issue of mercury accumulation in large fish, something that doesn't come up when consuming a steak. I recommend we eat very small amounts of meat and dairy from largely or entirely grass-fed animals to ensure we get enough zinc, B12, iron, etc. as well as protein.

[@WheresBillie104]

Dr Longo has on many videos stated those who skip breakfast live shorter lives. The meta study referenced started with about 400 studies and only ended up using 4. For everyone, their first meal of the day is breakfast. So nobody really skips breakfast. So is it the case that to live longer one must eat a meal before noon? How about 10AM? 8? What’s implied by eating “breakfast” is that there is some magic time for the first meal. And I can’t buy into that. People who skip a morning meal are more likely to have multiple morbidity factors, in my opinion due to lifestyle and poor diet. I guess I’m just not buying that skipping breakfast is bad because as I mentioned everyone eats breakfast and everyone eats over a range of time each 24 hour cycle.

[@orenelbaum1487]

So basically you just go by vibes

[@ktk2094]

Shouldn't we just listen to our bodies? If we're not hungry in the morning, don't eat. I know plenty of skinny people that don't eat breakfast in the morning.

[@JenKoning-v6i]

He mentions breakfast 12 hours after last meal. Don’t fast longer than 12 hours. 2-3 times a year do a prolonged fast. His FMD gives people who have a hard time with water fast an opportunity to fast. Get into ketosis and reap other benefits of fasting.

[@TrulsPen]

But if people have healthy markers of lipids and a1c and a healthy bmi will they see any improvements by incorporating fmd a few times a year? Probably not ?

[@joannasheldon2146]

It's not just about weight loss. It's about rejuvenation: shrinking all your organs during the fasting time, and after you stop fasting they regrow, necessarily with new cells.

[@link6563]

All the blue zones are surrounded by water, It is the fish not the plants. If plants made people live longer the blue zones would be all in land away from water. You know what does not grow in the Ocean? plants that is what

[@AtEboli]

Ever heard of seaweed? And if you study the diet composition in the Blue Zones, fish does not constitute more than a minimal part of the diet.

[@orenelbaum1487]

It's known people in blue zones are all on carnivore diet eating exclusively fish

[@katiewall3033]

I do one meal a day lost 25 kilos

[@maggiv5401]

How is that relevant? They’re not here to talk about weight loss.

[@seanrodrigues12]

But you get zero autophagy at 12 hours.

[@eternalwarrior-yp2qx]

Exactly, it starts between 24 and 48 hours.

[@traceler]

Others top PhD's like David Sinclair and Mark Mattson think otherwise respect to fasting time, skipping breakfast and other things, and they have as much credential as Prof, Valter Longo, so they should be debating face to face with each other to see who is more correct with the actual evidence and research including controlled studies and not just epidemiological data collection. Also remember that Valter Longo has conflict of interest because he is affiliated with the "fasting mimicking diet" big time.

[@jerrysundin8425]

Interesting.

[@mowthpeece1]

And so is Sinclair. He pushes lots of products.

[@bitebonumbere1426]

Of the lot, Mark Mattson seem not to have any conflict of interest

[@Bilge-Tekin]

What are the views of David Sinclair contradicting this guy?

[@alexF1989]

This just isn’t true though - Sinclair is an advocate of calorie restriction. The implementation may differ but I think he is quite open about the benefits that fasting and autophagy have on the body. Referencing Longo’s book as a conflict of interest is unfair in my opinion. Proceeds from that book are donated to charity and Sinclair should not be considered a knight in shining armour here either. His promotion of for profit resveratrol supplements at Tally Health and work on NMN derivatives are far bigger conflicts of interest, especially when you consider that both are widely critiqued by peers in longevity science.

[@eternalwarrior-yp2qx]

I don't believe that this guy is honest. He never talks about prolonged fasting even though it has incredible benefits but always talks about his "fasting-mimicking diet". What's the point? If you want to fast, do it in the proper way.

[@orenelbaum1487]

Sure he invented it for fun

[@ktk2094]

It would have been helpful to tell us what a fasting mimicking diet is.

[@susandyment3432]

He is a respectable scientist and only talks about studied proven results. He will not state anything unless it is backed up with evidence.

[@teddybearroosevelt1847]

@@ktk2094It means that you eat few carbs and a lot of fats, cause your body needs to burn calories that are stored in fat cells in your body to be able to burn the fats. So your body will produce ketones and when you fast your body also produces ketones to burn calories stored as fat in your body.

[@jonwelch564]

​@@ktk2094well he won't do that, because Prolon is a box of food you buy for the week you fast. No profit if they tell you. Its for people who don't believe they can not eat for a week, this is usually because they are high carb eaters and therefore get hungry very quickly, samskde affect of carbs

[@lmyers9999]

I don't understand all the hoopla... just water fast and you don't have to sorry about all the Macros and bs.

[@tejasparikh6610]

Please reply

[@valscitrop8299]

This guy is saying different that many , many other so called medical experts are saying, so who to believe? I think this guy makes me confused and seems just advertising his work

[@beverleycumming1876]

Law of diminishing returns after 72 hours…this guy is not credible to me

[@Mickey_Bauer]

I don't know what happened to this guy, i liked him so much better a few years ago. I found a few of his early videos where he talks about amazing benefits of fasting and all the important processes that happen in the body in a fasted state. However, all the newer videos sound like he's almost discouraging people from fasting, unless you come to his LA clinic for "Fasting Mimicking Diet". He even advised his friend Jean-Jacque Trochon (Air France pilot) to water fast for 2 weeks before his cancer surgery and he told him to fast for 5 days once a month for a year, following the surgery. I just watched a recent video of two of them talking about it but it sounded more like an infomercial for the FMD clinic. Water fasting sounds a lot more natural to me than "FMD" that was invented by a person making money on it. I just learned that Soviet Union and Germany have practiced prolonged 3 week water fasting for more than 70 years. Their fasting clinics were even covered by the state health insurance. There is also a good video about prolonged water fasting by Dr. Guido Kroemer too.

[@endthedrugwartoday]

@@Mickey_Bauer hmm. I 'fast mimic' by just fasting. Dunno. Love it!

[@AnifreakGed]

​@@Mickey_Bauer It's because you can't sell a product when the protocol is literally don't eat lol. Fasting Mimicking Diet on the other hand can get you partially as effective as fasting, but with the benefit of making that sweet sweet dollar.

[@clicheshekels2708]

@@Mickey_Bauer Dr. Longo mentioned in an interview a couple of years ago that there were incidents of people water-fasting and passing out (one while driving!). USC was suddenly getting calls from attorneys for people trying to blame Dr. Longo for their water-fasting folly. He said that he was now having to be much more guarded when it comes to water-fasting.

[@Mickey_Bauer]

@@clicheshekels2708 that makes sense. Maybe his heart is in the right place but unfortunately in this country everything is about lawsuits and getting easy money so he may have to protect himself from all the pussies.

[@mowthpeece1]

I love how people think they know better than the leading expert. Hilarious.

[@mowthpeece1]

Just admit you don't like it or don't have the will power or just don't want to what he says. It's more honest.

[@markgoodwin183]

Perhaps they agree with another expert who has a different belief.

[@stefantrajani8514]

He mumbles it and talks with both ends of his mouth...not clear what he recommends

[@heidiroy-boy]

He's REALLY HARD to understand..his accent is too much

[@baranjan4172]

perhaps you don't get the lingo as you are no doctor? no problem here. is your English good enough?

[@TrulsPen]

His English is perfect but maybe you’re used to a less educated English? In that case you can read the transcripts….if you know how to read that is

[@thevcountdown9824]

Strange, my mother language is German and I understand every word he says. You sound very racist.

[@vybezkartelz8651]

You most likely have an undiagnosed learning-disability. Its quite common for these things to go unnoticed even in adult years. you many want to get checked out

[@jerseytony1]

@@baranjan4172 He knows more than one language,, How many you know @heidiroy-kerckhoff1527