Fix YEARS of sun damage | DNA Repair Enzymes

[@ilkasiegmund247]

Fascinating!! Can't wait for more videos of this subject! I'm also paying for what I did in my 20's. Great video Penny!!

[@Colwell_2015]

You are hands down my absolute favorite Penn!! Thanks for sharing your wisdom with all of us ❤️ What’s your thoughts on using DNA repair after microneedling? Would you hold off a couple days before applying?

[@Shakithedingo]

Would you be able to do a video on microneedling with active acne? I bought the Dr. Pen Ultima M8 months ago and haven't used it yet as I literally always have one or two pimples and I'm terrified of doing something wrong and possibly spreading the bacteria. I love your videos, you're the only KZbinr talking about microneedling that I feel I can actually trust! Thanks so much :)

[@sarahj6237]

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[@elettramia6380]

No, that is one of the major rules. NEVER micro needle on active acne because it spreads the bacteria and makes acne worse

[@obssesivefan1437]

As a bio major… I’m so impressed by sound well done this videos is. Kudos 🥰

[@PENNSMITHSKINCARE]

Oh thank you!

[@beverlybzdek-smith9604]

Great information I read through the comments however, I'm still wondering about these serums/creams getting past the skin barrier to where the DNA repair would be most effective. You mentioned a liposomal delivery system, will that allow the enzymes to reach the level where they can do their repair? Or is it even necessary, can the repair occur superficially?

[@PENNSMITHSKINCARE]

The liposomal delivery aids their penetration to where they are able to boost the body’s ability to repair itself. I completely agree that many topicals cannot pass the skin barrier, but liposomal encapsulation allows for penetration (at least in this product). When I ask more questions I’ll try and get this answered more specifically for you ❤️

[@deborahcole593]

@@PENNSMITHSKINCARE Can the Photozyme Youth Serum be added to the cosmetic needling protocol you suggest (toner/essence, CN at 0.25 with HA, rinse HA, apply copper peptides, growth factors, retinoid, moisturizer, etc.)? If so, when would you apply it. Thanks so much!!!

[@devonengle3894]

How are Oneskin's products different to the photozyme products? do they both do DNA repair?

[@kimgarrison2904]

What a fantastic topic! As a 56 year old woman from South Florida, I am now fully seeing the impacts of 30+ years in the sun. This could be my silver lining. Can't wait to hear more. Thanks so much.

[@HollyL56]

In my 50's as well and we did some dumb things regarding the sun when we were younger huh? This is exciting info.

[@kimgarrison2904]

@@HollyL56 I lived at the beach. Covered in St. Tropez or that other wonderful smelling one and layed on a silver reflective blanket. I have a lot of olive in my skin and I was always so tan - year round. I never even knew about sunblock. And did anything to avoid tan lines. Today, I'm paying the price x 10 and am following all the rules, but I'm not going to lie, I love how much healthier I look and feel with a real tan.

[@HollyL56]

@@kimgarrison2904 same, been a beach girl most my life but definitely have changed my habits as I’ve gotten older.

[@ALT-vz3jn]

@@kimgarrison2904 Bain de Soleil was my favorite 😍 the scent was amazing!

[@maureengreen617]

@@kimgarrison2904 At least you can start your repair at 56. I'm 65 and only started cleaning up my sun-filled youthful indiscretions 3 years ago! Argh. 😱😂

[@sperkins5244]

HI, Penny! Thank you for your research. I'm interested in the red light & near infra red LED light therapy for use after microneedling to help build collagen. Can you give information and the adjustable lamps that have these LED's. They are so much more useful for focusing attention on other parts of the body. Also, is there a way we can be sure the LED's aren't giving out radiation, such as mobile phones do? Again, thank you for very interesting videos and all your hard work! Hugs.

[@jaimeamador5034]

Thank you, Penn, for the in depth video! I bought Photozyme’s body cream when you previously talked about DNA repair enzymes and I’ve been using it daily for about 2-3 months. I have been dealing with AKs on my forearms and hands for years and I have seen significant improvement. A few years ago, a dermatologist told me there was nothing that could be done to help me and I refused to accept that answer. THANK YOU THANK YOU THANK YOU for bringing attention to such an important subject! ❤️

[@PENNSMITHSKINCARE]

This is so wonderful to read!! Jaime thank you so much for sharing! ❤️

[@MBmysterio]

What does AK stand for?

[@jaimeamador5034]

@@MBmysterio Actinic Keratosis

[@MBmysterio]

@@jaimeamador5034 Thanks for letting me know.

[@insideoutbeauty3170]

love this information Penne thank you so much ! Bought the phytozyme body lotion, love it. Will get the serums. I have the Neova but like you am not crazy about the camphor.. .so i keep it for my sun damage on hands and arms. Thank you again for your diligent information and your calming presence. Love you XX

[@theresanoble4687]

How does it know the original DNA blue print prior to damage?

[@PENNSMITHSKINCARE]

I’d have to ask this question-and I will! I have a theory but I have to ask this of the experts 😊❤️

[@TVKad]

The DNA is damaged usually on only one strand, the second strand acts as a template for its correct repair. The beauty of DNA is its inherent coding redundancy.

[@theresanoble4687]

@@TVKad thank you! Do you have any knowledge on correcting psoriasis attacks?

[@TVKad]

@@theresanoble4687 sorry, no

[@HotMessNessMUA]

Thank you for all of your research and the time you spend testing for us ! I am definitely getting the body cream when it restocks ! My arms look way older than the rest of me because of sun damage. Xoxo

[@AnnSwansonWellness]

Penn, I love my Photozyme! And the texture of the Neova Silc sheer is phenomenal. However, I got a bit concerned when I saw Octinoxate was in it at such a high percent-3%. Does that concern you?

[@anareich]

Finally have products that work on my sun damage. Ordered photozyme md dna youth recovery straight away after watching this video. Came fast. AM/PM with Alive by science renue age defying lotion, and vit c and sun screen AM and retinol in PM- that’s all I need. Expectations were low I have to admit. It’s true that sun damaged skin looks and acts so much older. Feel like I’ve had 10 yrs wiped off in just a matter of days.

[@PENNSMITHSKINCARE]

Yay!!! That is so amazing to hear! I’m testing the Alive by Science products now 😀 You love those also? I bought all of them-so I’ll report back ♥️

[@DeeDee-rr3sn]

🌻 as always great videos and Penn! The only thing I question about these products is, if they can do what they claim they can do then they need to be FDA approved because they're technically a drug.

[@sams8808]

Hi Penny! I love your channel. I'll be buying a microneedling pen using your amazon link soon, but I wanted to confirm the process with you and gets some questions answered! When microneedling You first wash your face then use a 70% isopropyl alcohol swab to the area. Then add the hyaluronic acid to the face then gently apply the pen with no additional pressure allowing the pen to glide? Then after refrain from washing your face for 24 hours. Is this correct? I was also wondering if it was safe to microneedle other parts of the body? I have scarring on my arm and would like to use the device there at well. Should I shave the part of my arm before doing so? Is this the correct serum to use? Pure Hyaluronic Acid 1% Powder Serum for Face 10,000ppm - Anti Aging + Fine Line + Intense Hydration + facial moisturizer + Visibly Plumped Skin + Prevent Bladder Pain (2Fl Oz) Visit the Cos De BAHA Store (found on your amazon list link) Also, should I get a new bottle of Hyaluronic acid every time I microneedle? I am concerned about germs getting in the bottle after it is opened. Would you recommend I get a box of sanitized eye droppers to use with each new microneedling treatment so I can use the same bottle of serum, but always have a sanitized application? Thank you so much :)

[@alli_loves_skincare7842]

Great information Penny, as usual. I too am dealing with sun damage from hose young days basking in the sun with baby oil. 🙈 DNA repair enzymes sound promising and I definitely will try one of these. Does plankton, red algae always work in a DNA repair capacity or does it depend on the formulation?

[@nita4684]

Great job Penn...you make it relatable - explain it in simple terms so that those of us that are not scientific can understand...Thank you so much

[@KellyLudwin]

Time in the sun in the past but now my menopausal skin plus the sun damage is coming home to roost

[@PENNSMITHSKINCARE]

I’m right there with you kelly!!

[@crissyanderson6495]

I know exactly what your talking about! I spent years baking in the sun with baby oil when I was younger and then peri menopause hit!! It’s like I woke up one morning and didn’t recognize myself 😱🤣🤣

[@cp4184]

The body lotion is sold out. What is ridiculous to me is that they charge shipping if the order is under $100 and of course all of their products with the exception of the cleanser are just under $100. Shipping should be free for what they charge. I do appreciate the explanation and taking the time to bring us new innovative products to help keep us looking great. Thanks!

[@izziwizziranaway]

They don’t sell outside the US either. That’s rubbish.

[@iriskaufman5048]

Hi Penny, is there UV damage app so that we could assess out damage and monitor progress the the DNA repair products ? Like the black and white photo on your video ?

[@PENNSMITHSKINCARE]

Yes!! It’s called “UV scan” and I got it in the App Store for $2.99 I’m going to track progress also. That should be interesting since it’s summer 😳

[@iriskaufman5048]

@@PENNSMITHSKINCARE thank you, great to be able to get objective assessment of our damage and track our improvement with these products. Excited

[@PENNSMITHSKINCARE]

Totally agree! I am going to take pics of my hands too (I haven’t yet, hoping I can with the app) to judge improvement there also. ❤️

[@reddhottsc1557]

Please if you would show a picture of the icon for the UV scan because there are a 100 when you put that in the Play Store search.

[@HollyL56]

I really want the Photozyme Body lotion, can't wait until it's back in stock!

[@Misskitty15]

Penny, I called the company about photozyme but the guy, Greg, couldn't tell me for sure if the nonapetide-3 is a nano particle or not. He said it penetrates the cell membrane (which is dangerous, imo) & there are patents on the ingredients so they are not something normal for the body (& could be synthetic?). Can you tell me if these products have nano size particles in them plz? Because anything nano size can go anywhere in the body & cross the blood brain barrier!

[@tcwc5928]

Oh my goodness- the Neova Silc Sheer is such an elegant sunscreen! It’s had a very subtle tint. I’m extremely pale and it doesn’t seem to leave very much color at all so it may be too light for deeper skin tones. It’s not greasy at all. Why do I have to fall in love with such an expensive sunscreen!

[@PENNSMITHSKINCARE]

I don’t know but I also fell in love with that expensive sunscreen dang it! Lol

[@audreybialas9384]

I am beyond thrilled that you are covering DNA repair enzymes at such depth. I bought all 3 of your top recommendations when you talked about them in an Amazon live about 2 months ago and was immediately impressed and hooked. Started to do my own research. Listened to a webinar with the creators of Photozyme that’s on KZbin. I’ve had several bouts of basal cells. These products seem to be helping with the Actinic Keratosis. They even eliminated a strange spot that popped up out of nowhere. Not even a trace of it in less than two weeks. I’m taking the oral B3 and this seems like a perfect 1-2 punch. I can’t thank you enough for bringing these products to light and educating us all. You are the BEST!!!! 💕 Forever grateful. I can’t wait to learn more in your series!!

[@PENNSMITHSKINCARE]

Oh my gosh Audrey-this literally makes my DAY!! The skin cancer aspect is the most valuable to me-I’ll be diving in to that much more in the coming weeks. Thank you for leaving this comment….it just makes me so happy that you are getting results!

[@LisaNix2]

How are you doing now 2 years later? Do the products still help you? My Derm just suggested to me to use Isdin SPF for the dna repair. Just saw this video

[@Blondie727]

Could you do a video on Heliocare supplement? Is it worth buying & does it help prevent damage from the sun? I know that it’s not a substitute for sunscreen. Thanks.

[@m.younis9849]

Following!!!!

[@lauranicole9810]

I have had basal cell on my right cheek removed 6 yrs ago , I just had another spot (basal cell) removed on my nasolabial fold on the left side this past Monday would this product help prevent this cancer? Do you have any other recommendations ? I go back the Dermatologist in Aug for a full exam . Thank you for this information ! So helpful.

[@sara_387]

I’m interested too. I just had an infiltrating BCC removed, which is high risk, and I have started taking oral B3 nicotinamide, 500mg twice daily. I buy Blackmores Insolar. It helps with DNA repair. In studies of high risk (recurrent) skin cancer it reduced rates by 20-30%, the effects were greater the higher risk of recurrence. I’ve been reading on the topic and it seems that the DNA may be slow to repair in those that have recurrent skin cancer. It probably goes without saying to also change your lifestyle/sun behaviours...in the study on oral B3 they stated that a significant number of the patients hadn’t worn sunscreen in the week prior to their appointment. A sunscreen with high UVA protection and hats/protective clothing as UVA may reduce the skin’s immune system and further slow the DNA repair. UVA is also level throughout most of the day...so there is really no safe time, contrary to the vitamin d advice.

[@sara_387]

www.molemap.net.au/skin-cancer/vitamin-b3

[@lauranicole9810]

@@sara_387 Thanks! Yes I always where sunscreen and hats . I have not sunbathed in over 40 years, but back in the day they did not have the information they have now about the effect of prolonged sun exposure .

[@PENNSMITHSKINCARE]

I’m going to get you (all) some info on this. I wanted to answer you but given the importance of the question I am running this by the scientists and also going to pull some research for you to check out. I have had a pre-melanoma removed and while it was early it still scared me. I’m sorry you’ve gone through this and I’ll report back ASAP!!

[@sara_387]

@@PENNSMITHSKINCARE thank you so much 😊

[@LadyTamika]

You really got me into it. Relly great video and an important subject. But what about Retinol, Tretinoin , Sculplla ( PLLA (poly-l-lactic acid))? What about Anti-Oxidants? Are they going to be replaced by DNA Repair Enzymes? After I watched your video I put DNA Enzymes in a Search Engine and there was an article on www.getthegloss.com, Dr. Moy says there "Antioxidants are about a 50-year-old theory that we've since made improvements on - instead of potentially mopping up DNA damage, we now know that we can attack damage head on. Retinoids kind of fall in the same boat. I used to be a huge proponent of retinoids myself and I still think that they are great, but the industry is lagging behind. What science has found is that growth factors [another ingredient in Dr Moy’s skincare] are actually a way more effective and significant improvement on retinoids." - Hm. I wonder what your opinion is and if we should use combinations? If yes how would the protocol look like? Sorry for being so long in my comment, but I do not know how to ask it in a shorter way.

[@shaynek.3806]

Such a great analogy and explanation !!! Wish you were my esthetician ❣️

[@PENNSMITHSKINCARE]

Thank you Shayne! ❤️

[@shaynek.3806]

@@PENNSMITHSKINCARE ❣️

[@catherinedesilets8960]

Hi, great video Q. I heard you say that 2 of the ingredients are light & heat activated. Could you please find out if then we could use this serum before using the LED mask to activate it even more? Thank you 🙏🏻

[@PENNSMITHSKINCARE]

Yep, I’m asking. I’ll report back ASAP. I have my theories and opinion on this but I think I need the experts to weigh in so I get it right for sure ❤️

[@catherinedesilets8960]

@@PENNSMITHSKINCARE Hi Beautiful any update on if we can use the LED with the photozyme DNA repair serum .. I have the Celluma but they tell me not to wear anything on the skin in order to absorb the positive LED effects Can’t wait to hear the update .. Maybe a idea for a new video? LED mask with DNA repair serum… Thanks 🙏🏻

[@bismaferoze406]

My skin got damaged after a deep microneedling. Now my face structure is completely changed, skin is textured, wrinkled and sagging downwards.. can I repair that naturally? It’s been 8 months

[@ALT-vz3jn]

Hi Penny, I bought the Neova DNA repair serum after watching your video. I’m 50 and have been using Skin Biology Copper peptides and AHAs since age 30; my skin is gorgeous but I’m noticing a little sun damage coming out on the tops of my cheeks, probably from sun tanning/sun burns in my teenage years. Is it ok to layer the DNA serum underneath the Skin Biology Ghk-Cu creme? Retinoids make my skin super-irritated so I only use them 2 nights a week, And I use AHAs the other times. I’m trying to figure out where to place all my products (I also use a 20% vitamin C skin refiner (Beautystat) in the morning and Dermalogica SPF50 on top) Thank you.

[@karynnotkaren693]

That was such a wonderful clear explanation! I wish you had been my science teacher. Thank you

[@PENNSMITHSKINCARE]

Oh my gosh, that is the very best compliment ever, thank you! You just made my night!

[@nita4684]

I agree...subject needs to be relatable...You made it so

[@clshanes10]

Hi Penn, what is the difference between DNA repair and growth enzymes? Do you recommend one over the other?

[@lakeside23]

In December 2019, you highlighted Defenage, which is a DNA product, but it wasn't mentioned in this review. Does that mean you prefer Photozyme? If so, is that related to the ingredients or something else. I've purchased Photozyme Youth Serum and Defense eye serum and am on the fence about what to order when they run out. Thank you for clarifying! I love your deep dives into the science!

[@insideoutbeauty3170]

Btw can i ask you which laser your would suggest if i wanted to repair my brown spot sun damage on arms and hands ? Thank you (:

[@Emmak1992]

What are your thoughts on the Alto Defense Advanced serum? It has plankton and micrococcus extract in it too (I think).

[@irynaml5559]

👉👉 I wish you find the same products but more affordable way 🙏😔❤

[@PENNSMITHSKINCARE]

The WINNERS: 1.Photozyme Youth Serum skinbeautifulrx.com/products/photozyme-md-dna-youth-recovery-facial-serum?ref=penn-smith code Penn20 saves 20% 2.Photozyme Body lotion (I love this one because it lasts forever and my body skin needs all the help it can get!) skinbeautifulrx.com/products/photozyme-md-omega-36-body-complex?_pos=3&_sid=e7f27c00c&_ss=r&ref=penn-smith code Penn20 saves 20% 3.Neova Silc Sheer amzn.to/3Pp6iY4 (this tinted sunscreen is lovely. I love the idea of combining my DNA repair with sun protection-effectively boosting it. An alternative ((and probably better protocol)) would be to use the Photozyme serum in the AM BEFORE any sunscreen. I'll probably do that again, I switched to a more minimal routine recently and have been just using it at night) The other products that I tested (I purchased every single product myself. I've been testing for months and months): 1.Neova DNA Damage Control Smart Moisture Daily Defense (this is lovely, but it made my eyes sting/water for some reason) 2.Neova Super Eye Lift Serum (this just didn't wow me. Not bad, just not for me). 3.Neova DNA Damage Control Everyday Facial Fluid SPF 44 (this one was actually quite nice but I loved the Silc Sheer so much that this one never got picked up). 4.Neova DNA Total Repair (this one irritated my skin-not sure why but I had to pass it on. The ingredient deck is great-just didn't work for me) 5.Priori DNA fx221 - Recovery Serum (this is another great serum but I love the texture of the Photozyme so much more. I passed this one on to a friend because I definitely think it's worth using. Just not as good as the favorite FOR ME). 6.Cellular MD Reparative Hybrid Mask (I did not care for the silicone feel of this mask. I didn't think it did much at all for my skin...not even hydrate. It was a dud for me unfortunately). 7.Cellular MD Intensive Eye Balm (I am actually still testing this one-working on an eye cream video. It's a beautiful texture and combines DNA REs + EGF. Interesting for sure. I'll report back!) 8.Celular MD Universal Protection Drops (I LOVE this concept. You add the drops to your own skincare-creating a DNA repair enzyme product of your own. Unfortunately it broke me out :((( That said, what an innovative concept!) Find NEOVA here: amzn.to/3dgTC45

[@S-Cosma667]

They only ship to US (photozyme).😔 I am based in UK.

[@munequitabluegreen7481]

I use medik8 retinal at night can I still use the photozyme serum in the same routine or should I only use in morning routine? Very interested in adding photozyme into my skincare

[@Leah777...]

Penny rocks! The neova dna repair I think is working for me 😃... Gonna keep going... We'll see. Thanks sis! ❤️

[@PinCushionQueen]

Penny, how do dna repair enzymes ( essentially plankton )benefit melasma sufferers? I’m not clear on that. Theoretically it makes sense that it would . I’m not keen on hydroquinone but I do use a multitude of pigment inhibitors to battle my hormone based melasma, triggered by hormone spikes during pregnancy & a lifetime of hormonal issues.

[@PinCushionQueen]

Penny, Paris Hilton has a whole skincare line with plankton starring heavily within her products, particularly the serum plankton being approximately 3rd on the inci list. Which is high compared to most I’ve seen. I’m really curious about it & her line in general, especially that serum. I’d love your thoughts!

[@bismaferoze406]

Do we have to use these products forever to reverse old damage ? Or using for some specific time can do the job to reverse the damage?

[@profitmakingonline]

I really want this but wondering if there is a more affordable option? I know you listed all the serums you tried but if you have pick a 2nd more affordable option, which would it be? I get confused since some serums say DNA on them but they are actually growth factors. Thanks Penn!

[@lifeison1]

Sesderma REPASKIN Gel post-solar is very cheap

[@JLeigh75309]

So interesting. I'm awaiting prescription azelaic acid - want to get that annoying redness managed as best I can before I throw anything more at it. Masks are disastrous with rosacea!!

[@enalo6261]

Have you tried MSM supplements

[@crissyanderson6495]

I completely understand! I have rosacea as well and have seen (3) dermatologist and they were all no help! So now I’m trying to manage it on my own. I hope your prescription works for you!!

[@dermlover1]

@@crissyanderson6495 Why were they no help? Did you even give them a chance to treat you beyond just one appointment and never following up? Just because we go to school for many years doesn't mean we can see you once and have your problem under control right away. It often takes trial and error. Jumping from one derm to another won't help. Remember, we are all board certified and learn very similar things in school and residency. We want to help you, but you have to give us the time to do so. It's very frustrating when patients say derms didn't help them. The majority of the time, it's the patient's fault the plan(s) didn't work because there was no consistency or follow through. In addition, patients can have way higher expectations for outcomes than any derm can offer. We are not magicians. Have realistic expectations.

[@crissyanderson6495]

@@dermlover1 thank you for your comment. I completely understand what you are saying but I did give each dermatologist plenty of time but after 2 years and countless meds and still no results, I think there is an issue. It’s very frustrating when you go to see a doctor and you try to explain your problem and present them with all your notes and findings (which I had plenty lol..) just to be dismissed after 5mins and prescribed the same medications over and over again that do not work. But, I’m not giving up because I know there isn’t a magical wand for my problems!! Thanks again and have a great day! 😍

[@wt1284]

Is sun damage the only thing this deals. My mother died at 52 with melanoma.

[@michellegerdes8993]

I’m new to your channel and watched a video from 3 years ago. Do you still use/recommend Clarista and can you only find it on Amazon? Some of their reviews weren’t good because they received an expired tube or the tube wasn’t full. Thanks for the videos. I’m learning a lot.

[@PENNSMITHSKINCARE]

I still love Clearista, yes! You can order it on Amazon (they are an authorized seller-so I’m not sure about the review) but you can also get it from Clearista’s website if you’d rather 😊

[@patricethrives8830]

Many of us were "stupid in the sun."

[@PENNSMITHSKINCARE]

I figured I wasn’t alone 😕

[@sonaligujral7620]

ISDIN is great for actinic damage. also contains DNA repairsomes.

[@PENNSMITHSKINCARE]

Yes! I love their sunscreens 😃♥️

[@jrmint2]

There are foods you can eat that help repairs DNA damage too.

[@Janhoy723]

Great content as always. Will Photozyme Youth Serum help with hormonal Melasma? Thank you Penny.

[@PENNSMITHSKINCARE]

That’s a tough one. I’ll see if there are any case studies on hormonal melasma. I KNOW that hormones impact the skin in a very profound way so I’ll have to look in to this. I’ll certainly report back!

[@Janhoy723]

@@PENNSMITHSKINCARE Thank you so much Penny🙏🏽

[@KrystalHartley]

This is why I incorporate near-daily autophagy fasting and less frequent extended fasts ( at least 58 hours). I’ve got that fair skin, head-to-toe freckles complexion. Susceptible is an understatement

[@PENNSMITHSKINCARE]

Totally understand this!!

[@allthethingswithmandyandwh8226]

How much of the youth recovery serum should you use? Is it just one pump? Would you apply it thinly like tretinoin or put it on heavier like a moisturizer?

[@Loralarify]

This is a topic I am fully immersed in ever since i was diagnosed with ovarian cancer and discovered through genetic testing that I have the BRCA mutations. I have both BRCA 1 & 2 for ovarian and breast cancer. Standard chemotherapy didn’t work for me because of my “freakish” DNA makeup. But gladly, a new state of the art Parp inhibitor called Rubraca, did work because it goes right to the source of the DNA replication process and interrupts the repeat of the issues these mutations cost- I’ve been on it since 4/2017 & have been on a reduced dose of maintenance to stay in remission. There are many factors I have to be checked for on a monthly basis with labs because like everything else, there’s always a trade off when you are on a drug this powerful. It is an antioplastic chemotherapy agent- in a pill form. Thanks for this most interesting video!

[@elena95464]

Sorry to hear that Laura. I hope things continue to go well for you. Blessings!

[@PENNSMITHSKINCARE]

WOW!!! This is so interesting Laura! I’m so sorry you have been going through this though-I know from the group that you are one amazing woman. I’m so happy to know you (even if it’s virtually) and now I’m going to study the therapy you are talking about! ❤️

[@Loralarify]

@@PENNSMITHSKINCARE T/Y 🥰 it’s quite fascinating … and even though I have these mutations- it’s actually been one of the reasons I’m still alive now. I have more options.

[@Loralarify]

@@elena95464 thank you 🙏🏼❤️

[@ptowey5298]

Thanks so much for this video. I’m a rabbit hole diver. I need this info, I’ve had melanoma 2x. On bottom of my foot. I’ve had at least 4 mohs surgeries on my face. I don’t know how I stumbled on enzymes, derm recommends neiva. I’m going to try 2 photozymes and neiva sunscreen, silk. Can’t wait to go down rabbit hole with you. I’m wondering systemically?

[@PENNSMITHSKINCARE]

Look up the book Primal Panacea. It talks about vitamin C in a way that may be really helpful to you! Also, look up Evy SPF. It is super long lasting protection. Last, in case it helps RescueMD is incredible for scars (if you have any from your Mohs surg). 💙

[@Vivi-qo1jl]

Hi, before I order Photozyne Serum can it be used at night with my retinoid? I definitely want to add this to my regimen. Im also going to try the body cream with fingers crossed......at 65 I have the dryest body skin on earth. Ive tried everything and nothing hydrates the skin on my body. Unfortunately I can't afford to use my face, neck and chest products on my body. LOL

[@PENNSMITHSKINCARE]

Yes, you can use it at night and with your retinoid!

[@Vivi-qo1jl]

Thank you.

[@carigalloway5517]

Is that a Journey tee !!!!!!!

[@lornaoyarce1355]

Oh gosh! I am so grateful for this information. I didn't do a lot of sun worshipping but in my lifetime I have probably had 2-3 burns that blistered and peeled and I have a pretty low Fitzpatrick score so.... I wish I could have my picture taken with that camera that shows the damage under the skin. Penn, did you think the ingredient decks of the other products looked good? I was intrigued both by the GFS Night Serum and the Probiotic Cleanser.

[@PENNSMITHSKINCARE]

I’m going to pull up those ingredient decks and check them out. I’m planning to test all the products but I haven’t yet!

[@lakeside23]

Love this informative video. You said Defenage does not need to be used longer than 6 weeks, so does that apply to Phytozyme also because they are so similar? If so, when would you begin using either product again down the road?

[@bismaferoze406]

Looking for the same answer

[@mjkambeitz7518]

Help I Need help dark spots appearing and raised … when I put fake tan on the pigment is pulled into these spots and it looks terrible. Would chemical peels get rid of this? Or micro needling ? It really horrible instead of a tan giving me a beautiful glow and evens out skin tone . I look splotchy dark spots are so pronounced on décolleté and My legs and chest . Thankfully not my face but it looks terrible … is body makeup my only go to now ????

[@WriterSnider]

Hot nerd! 😍👊 All of this is soooo expensive, though.

[@PENNSMITHSKINCARE]

🥰🥰🥰 I know, expensive! I bought all of them and trust me I SEARCHED for inexpensive options and to my knowledge they don’t yet exist. That said, I’m exploring the ingredients that can help the DNA repair process alone (like plankton) to understand their potential+ their difference to these products. Lots of less expensive products contain some of those ingredients. I’ll report back!

[@smtamez7025]

Hi thank you so much for this video. I jusy started using photozyme. I was very interested in DRMTLGY...have you found results with their products?

[@Meli27w]

Something burnt the crap out of my eyelids & I can’t figure it out but seeing this video I think it’s my sodium DNA 1000ppm creeping over my lids by accident.

[@taimikalewis1582]

Hello Penn :) Can you use this along side the 3% ghk VIP luxury Serum? I'd like to use them in the morning routine? sending love!

[@gevvlys8767]

Photozyme really is amazing, my skin is glowing and is so much more revitalized now that i have started using it! Thanks!

[@janedelaney4327]

When do you use it? And with what other products?

[@andrewr76861]

Love this topic! A lot of really interesting information. I just got the Photozyme VITAMIN C+E FERULIC serum with DNA Repair Enzymes. Looks to be a great product! I will be trying it out as soon as the Silymarin CF is out!

[@PENNSMITHSKINCARE]

I’m so tempted by they vitamin C and also their face cream. They’re on my list to try! 💕 Happy Saturday friend!

[@lillynono3711]

I have very bad discoloration on my neck and chest from sun damage. My Derm told me there is nothing to be done about it. I am currently trying Queen 7 but maybe should go to the DNA repair products?

[@jodieharris5309]

Do you recommend YOUTH RECOVERY FACIAL SERUM , Is that the right product name?

[@catherinedesilets8960]

Oh oh I just tried your link to order the photozyme youth serum & it doesn’t allow me to put my Canadian mailing address? Is it only available in the USA?

[@randykriech713]

In Canada you can order the Photozyme products under the name Rejudicare Photozyme by RGR Pharma

[@catherinedesilets8960]

@@randykriech713 Really? Okay thank you I’ll try that I appreciate the help :)

[@PandaA-cv3mm]

@@randykriech713 Do you know if there is a similar situation in U.K.? Can’t seem to get it here either. Thanks 😊

[@LizK6457]

The DNA Youth recovery directions say to apply “one metered dose” to the affected area. Does that mean one pump? I have seen you use 4-5 pumps on your face. I am wondering how much do use. it’s an expensive product but I want to use enough for it to be efficient.

[@PENNSMITHSKINCARE]

I really used too much. I would say 2 pumps is great for face and neck 😊♥️

[@LizK6457]

@@PENNSMITHSKINCARE Thx. 💜

[@Waltonmx]

Great info as always. I love your videos. Also, your top is so cute. May I ask where did you get it from?

[@maysamabeauty1839]

So informative Penn 🙌🙌 💚

[@austinq3151]

Did you try the photozyme c e ferulic serum? I didn’t see it mentioned and I’m mostly interested in that because it still has the dna enzymes and a short ingredient list

[@PENNSMITHSKINCARE]

I haven’t tried that one yet, but I plan to ASAP!!

[@austinq3151]

@@PENNSMITHSKINCARE looking forward to the review! holding off on using the discount code for now b/c my current vitamin c serum still has plenty. I'm leaning heavily on trying out the photozyme one though :D

[@anacaballero4366]

Have you tried Osmosis Catalyst AC-11 DNA Repair or their rescue serum? This has helped with my hyper pigmentation and overall appearance and texture.

[@antoniettabonfigliovetere1195]

Great analogy with the cake recipe Penny!

[@molliewongful]

@PENN.SMITH.SKINCARE, is the product the same as the Growth Factors used after micro-needling? Would you recommend it for that use? Thanks!

[@kimzorza1543]

LOVE your shirt!! My all time favorite band ever!!!! Great video!

[@PENNSMITHSKINCARE]

Thank you!

[@a3yeung]

Thank you for sharing this latest and greatest and I bought 2 bottles to try! Because of you, I have been doing all sorts of skin care and diy at home following all your instructions! Thank you!

[@moniquedubos6612]

Penny, any chance you've been able to procure a discount for your followers on the Neova Silc Sheer Tinted Sunscreen SFP 40?

[@julufitness7349]

What a great video! Wondering how the Osmosis MD Catalyst AC-11 would stack up in this comparison? I’ve been wanting to try it but not sure how effective it is! Have you tried it, Penny?

[@tishacarr988]

Do you think these enzymes can completely reverse DNA damage if you are very consistent in applying them?

[@ellenmuthexperiments2254]

fascinating! When you, and the dr. you had on in your recent videos regarding enzymes that repair DNA, say certain enzymes need light to work do you mean regular daylight and its not meant to be used at night time or does it need LED, UV rays, etc?

[@PENNSMITHSKINCARE]

Regular daylight-but blue LED light would work as well ♥️

[@michele5214]

How do you activate the serum with light if you're using it in the evening?

[@luv2garden132]

I'm curious. Le Mieux doesn’t seem to have the required ingredients that's required for DNA repair. Did I waste my money? What's the benefit of Le Mieux...are growth factors different than DNA repair? I don't know much about nothing it seems...lol

[@PENNSMITHSKINCARE]

I just did an updated video on DNA repair it is packed full of information kzbin.info/www/bejne/fpqZdWp3hs16mdU

[@meganNefarious]

OMG love your top!

[@janedelaney4327]

Thanks for letting us all know about photozyme. Great product.

[@valbrooks2699]

I take Resveratrol and Nicotinamide

[@saraadams8397]

Thank you for breaking this down so we can have a better understanding!

[@PENNSMITHSKINCARE]

Thank you for watching Sara!

[@Lifewith21catsand2dogs]

Great now I need to know your new pm routine after seeing your new am routine and now you are mentioning your night routine ..so I'll be here hoping for your new pm routine

[@cathymartine6034]

Darn it's sold out! :( must try! Thanks Penn!

[@PENNSMITHSKINCARE]

That was an error, it’s in stock! ❤️

[@debbiedejager2948]

Very interesting topic, and good to know there are products addressing this issue which I’ve always been told by dermatologists is not possible without lazer treatments etc etc. . Very much Looking forward to your interview with them about the research and development work behind the product.

[@ilkasiegmund247]

Fascinating!! Can't wait for more videos of this subject! I'm also paying for what I did in my 20's. Great video Penny!!

[@SimplyAmazing247]

Hi Penny! Can you do a video on how to find the molecular weights of serums and what serums to are best for different skin types??

[@MariaMLoBalsamo]

Hi Penn, can you recommend a self tanner product.

[@PENNSMITHSKINCARE]

Yes, I discovered Coco & Eve last year and it is definitely my fave now!!! I talk about it in this video at the 11:30 mark kzbin.info/www/bejne/jJeccqh5ocefrtk Hope this helps 🥰

[@MariaMLoBalsamo]

@@PENNSMITHSKINCARE Thank you! Do you have a before and after video? And also, have you ever used Tan Physics True Color? If so, thoughts on this one? I just saw it the other day advertised. Thanks again

[@PENNSMITHSKINCARE]

A before and after self tan video? I don’t. I am not crazy about doing much body footage honestly 😊

[@mariyastoyanova9116]

Can i use whit my tretinoin cuz there is retinol in it?

[@sterlgirlceline]

🌟🌟🌟🌟🌟🌟🌼💛

[@jojolina71]

A very interesting new field of interest Penny! You digged for us ‘through the weeds’, and thanks for the biology recap as well! I am looking into it, and follow the subject, ⛱⛱⛱

[@lilychen74]

how long does it take for the sun damages to fade once you start to use the product?

[@PandaA-cv3mm]

Thanks so much beautiful! This is really exciting. ☺️🌻💜

[@noneofurbusiness5223]

HOW do the enzymes work?

[@PENNSMITHSKINCARE]

It’s a liposomal delivery system that mimic the bodies process of carving out damaged DNA and replacing it with healthy nucleotides (as in the video illustration). I’ll be diving in deeper in the coming weeks and can get even more specific-this was an overview (I didn’t want to put people to sleep 😴) ❤️

[@rw3486]

It seems like the benefits are more than just cosmetic. I wonder if dermatologists could offer prescriptions and leave us with just a copay.

[@PENNSMITHSKINCARE]

I know that it’s actually mostly sold through dermatologists-and it would be a great conversation with your derm! 😃❤️

[@jeannek5448]

Interesting subject. I wondered about the Photozyme gfs plus serum that has growth factors peptides and dna repair enzymes sounds like a good all in one product. Thank you.

[@PENNSMITHSKINCARE]

Yes!! It’s a great one!

[@conniesands6967]

Can you; use a derma roller when using the product or is it best to just apply the product to face?

[@PENNSMITHSKINCARE]

You don’t need to dermaroll it in, so I’d just apply it ♥️