Fructose- Signal Disruptor Extraordinaire

A huge plug for the Peter Attia, MD Podcast where he interviews Rick Johnson, MD. This is the most amazing descriptor of how a signal disruptor to metabolism can cause incredible mayhem.

[@williamdennis1537]

“This guy can educate you without taking his shirt off.” LOL, Doc, thx for that, my day just got a little brighter. Guess I’ll go outside and slap around some iron- slowly of course.

[@mws121269]

Love the part about a doctor that can educate with his shirt on 😂😂😂 💯💯💯💯💯💯

[@DamaniJones]

Hey Doug, if you liked learning about fructose, I think you’d love to see how [industrial] seed oils also contributed to the explosion of metabolic disease (arguably a bigger deal than fructose). Dr. Cate Shanahan’s book “Deep Nutrition” is a great resource for learning about seed oils.

[@rblongfellow]

Check out his video from a couple years ago on specialized pro resolving mediators. It would be good if he did an update on this, if he still uses it

[@guitarista666]

I bought both of Cate's books. It looks like she is really on to something. But it was Doug who tipped me off to the problem in one of his videos. I started digging around and found Cate.

[@americanthaiboxer7224]

Best sign-off of all. "Do some dope 💩". Body By Science changed my lifestyle, Dr. McGuff!

[@loveartist5043]

• Seventeen people were made to eat twenty servings of fruit a day for up to six months. Despite their extraordinarily high fructose intakes-presumably the equivalent of drinking about eight cans of soda a day-the investigators found the subjects actually lost weight and their blood pressures improved,2253 insulin levels dropped, and cholesterol and triglycerides got better.2254 This is the opposite of what one might expect eating the same amount of fructose in added sugars. Why do our bodies handle the sugars in fruit differently from the sugars added to foods and beverages? Meyer BJ, van der Merwe M, Du Plessis DG, de Bruin EJ, Meyer AC. Some physiological effects of a mainly fruit diet in man. S Afr Med J. 1971;45(8):191-5.

[@digga95]

This is answered in the podcast. fibre and water in fruit is what human suggestion evolved to handle

[@donnahelps5680]

Do we know what diet they were coming from though? If they were coming from a healthy diet pre experiment then the changes in weight, BP, blood lipids, etc., would be impressive. If they were living on deep-fried Snickers and supersized Cokes then almost ANY dietary change would improve their numbers

[@aliendroneservices6621]

Seed-oils are more of a concern. See: Chris Knobbe and Tucker Goodrich.

[@janburch3923]

Your channel and P Attia are my go-tos.

[@BRM101]

Doug I know you probably don’t read the comments but is just like to say people should subscribe like and even comment on your videos as it doesn’t take long and the more activity on channel the more the algorithm will suggest the videos and the more people will see the videos which is good for everyone 😎.

[@JonathanLaRiviere]

I listened to that last week while working out at planet fitness. Fantastic listen, I might even give it a second listen! Right after I finish your book Body by Science on audible!

[@peteragov4181]

great video. thanks Dr. Doug McGuff

[@StephenTack]

Yep, absolutely a 🔥🔥🔥 episode. 🤘

[@StephenTack]

BTW. Thanks to Body by Science I'm up 10Lbs of muscle (and a lot of strength), for the first time ever, despite (mostly in remission) rheumatoid arthritis. 💪 Cheers!

[@CUBEOFSIX]

Doug, it feels like you’re transitioning over to a carnivore diet, it will be great to hear your thoughts on it. In my opinion, the science, archeological evidence, and our human anatomy is without a doubt clear that we adapted over 4.5 million years to be hyper carnivorous.

[@CUBEOFSIX]

@Evan Hodge appeal to authority. If you need academic professionals: * Dr Bart Kay - Senior Lecturer in Clinical Physiology, Cardiovascular and Respiratory. He’s written multiple published peer reviewed science articles, including research projects, and reviews of literature; in the areas of biochemistry, physiology, physiological modelling, statistics, and nutrition. He’s also acted as a subject matter expert peer reviewer for submissions to 3 different academic journals. * Dr. Paul Mason - medical degree with honors from the University of Sydney, and degrees in Physiotherapy and Occupational Health. * Dr. Shawn Baker, MD * Pim Jansson - Nutritionist (MSc), Biomedical Scientist (BSc).

[@christianwithoutreligionne3082]

good stuff, doc!

[@BRM101]

Keeping it real as always Doc 💪

[@raraavis7782]

Will check that podcast out 👍

[@CheckYourPremises]

Oh, my! If Dr. McGuff with his medical degree still cannot get it ... forget about average Joe. At least he managed to understand the :industrial seed oils" part

[@johntibaldi9496]

Rick said that high levels of glucose in the liver also convert partly into fructose. So it’s not just soft drinks

[@vc8160]

Yep, it’s very true. That’s why dr Shawn baker is 100% regarding a carnivore diet! It’s has helped so many people recover from disease. I was a stout vegan and believed every word that dribbled from the medical medium - Anthony Williams, until going carnivore and eating 2lbs of rib eye daily and nothing much else. Unless I had tried it I would still be suffering.

[@richiemac2395]

Dr. What are your thoughts on taking a tbs of brown sugar just prior to working out in order to prevent muscle breakdown for energy?

[@moderndaysparta7770]

Will definitely check out the podcast. I agree with your observation - the average weight in the US began to hockey-stick in in early 1970s, which was when high fructose corn syrup and soybean oil both hit the market. Double whammy. Farmers rotate between corn and soybeans. (And corn is hugely subsidized - Iowa alone gets about $1 billion per year in corn subsidies. They also hold their primaries first during election years, making them a 'must win' state, trying to scale back the corn subsidies would be political suicide.)

[@fitfrog65]

The 70's began the fake food movement, given overpopulation that was the only way to provide enough food. Food became fake and plentiful leading to the overconsumption of everything including meat. Obesity is merely calories in/ calories out not one magic food type.

[@summondominion]

Eating a few berries and fruit is NOT the sane thing as high fructose corn syrup.

[@moderndaysparta7770]

@@summondominion indeed it isn't

[@summondominion]

@@moderndaysparta7770 its crazy how many ppl i see on the internet making videos saying dont eat fruit its bad bc of fructose lolol.

[@summondominion]

@@moderndaysparta7770 if ppl actually researched there is actually very little fructose in fruit...as far as quantity per portion size

[@ismailmoola864]

In one of your lectures, you sated "All energy that's in our body comes from the sun. When something deviates off that line via processing this signal gets disrupted and your body doesn't know what to do with it. When there's massive signal disruption in your body any dysphoria at all gets misinterpreted as hunger, if you're thirsty you're hungry, if you're upset you're hungry, if you're bored you're hungry. In this lecture you alluded to resources one could study on this. Please outline these.

[@ralphbuschmann740]

Thanx!

[@opita]

For those interested, Peter Attia episode... kzbin.info/www/bejne/jGGVq2yjprmKsMk

[@raraavis7782]

👍

[@stringlarson1247]

For a deep dive into 'sugar(s)' see kzbin.info/www/bejne/mnPRn5yrlptgpa8 Dr. Lustig also has several more recent talks and interviews which are a little easier for the layperson to follow and understand.

[@christopherpike9464]

I was wondering if you know what percentage of the US population participates in resistance training? The National Center for Health Statistics has a number around 23%, but I think they are greatly overestimating. The reason I say this is that they ask people if they participate in "muscle building activities", which is ambiguous. People who do yoga or calisthenics would probably consider what they do "muscle building". I suspect that the number people who doing actual resistance or weight training is a small subset or this group. Do you know what the percentage is? Thanks for any assistance.

[@markallisonparamotor]

Love it

[@tomstrong4764]

Thanks, good info. For a T1 diabetic, would glucose rather than fructose be preferred in hypo scenario?

[@robwilliams2265]

Doug, I have been training at your facility for the past few months. Do you have any recommendations for recovery, or pre/post workout nutrition. I am making very good progress, but I am so drained that it takes many hours for me to recover to just a normal State again. Any advice would be appreciated

[@richardmccoy8560]

I have a question. I enjoy your podcasts. My observation and question is: of all sports, gymnasts have the best physiques and muscle mass to body size but the type of workouts they do to practice their gymnastic skills and routines is nothing like HIT. So, why is HIT better than whatever gymnasts do?

[@adrianwalker5415]

Better is subjective. They are training for strength in certain movements on the bar etc. While the vast majority aren't. Training for those certain bar movements can require 30 plus hours a week. When you say best physique the average male gymnast is gonna be in great shape and have great definition yes. But that's on the average male weighing less than 150lbs and a height of 5'4-5'7 so in reality you don't need that much muscle on a small frame for it to look great. Add a low body fat lvl to that frame he will look much bigger

[@JH-dr6do]

Gymnasts have those physiques because that body type best excels at gymnastics. Just like basketball players are tall and lanky. Has nothing to do with how they train.

[@HammyGirl999]

Top level gymnasts often started as a small child… with long enough workouts and high intensity, high impact such that their development is changed to grow a shorter and more dense/strong skeletal structure. So they are not necessarily born that way… though genetics help. Also if you are not a pro gymnast or pro Athlete you may not have time to train that many hours per day. Dr McGuff’s program is awesome for average health-minded people.

[@hungrymynd5673]

JH nailed it, unfortunately it’s genetics.

[@fitfrog65]

Don't they have underdeveloped leg muscles? What about aerobic capacity?

[@alicantuncer4800]

Does this also apply to fructose from fruits?

[@deanpaulson6714]

What are your personal thoughts on the carnivore diet? As Kinda crazy as it sounds I have been watching a few of the leading influencers on the diet and from a human evolution point it makes sense ! Also a lot of studies coming out on the healing and regeneration benefits of ketosis! Thanks for all the content you have put out over the years I know a lot people personally that you have influenced to take up strength training. For me personally having fruit or honey around is a deal breaker, the dopamine hit makes it hard for me to moderate ! I could easily eat half a dozen pieces of fruit In a sitting ! Steak , eggs and fatty meat I eat to satiety game over ! If I had fruit available I would switch into another gear . I been on this diet plus some fatty cheese and heavy cream about 6 weeks probably fat adapted now . I am doing for 3 months see how my health markers and well being pan out

[@loganw861]

I tried it and I feel amazing, I’m lean so I added in fruit, honey and sweet potatoes.

[@deanpaulson6714]

@@loganw861 I have looked at the twist however EVEN the WHO is advising limiting to 40 > 60 g a day . And evolutionary we wouldn't have eaten plants or fruit ! Possibly some seasonal fruit but it would have been sour all our fruit and veg today is modified to be sweeter and more tolerable

[@loganw861]

@@deanpaulson6714 the WHO recommends seed oil, That’s a disqualifier for me of taking any of their advice

[@deanpaulson6714]

@@loganw861 I think Ketosis is looking like it's the bodies self repair system ! And it makes sense ! More and more good research coming out ! Of course it's free so it won't go mainstream

[@loganw861]

@@deanpaulson6714 I think fasting periods are the bodies repair time, which naturally uses stored fat as energy bc that’s all there is. Fasting and Keto are the perfect first step to correcting any metabolic issues caused by a modern processed diet (seed oils, processed sugars, grains.) Once healthy / “metabolically flexible” (which means the body can tolerate fat & tolerate carbs without extended blood sugar spikes) adding in fruit & honey will be beneficial Long term. Natural fructose is perfectly fine when not insulin resistant. Many years of Keto drives fasting blood sugar level over 100, even to 110 plus. I know that seems paradoxical but the body is complex.

[@loganw861]

Processed Fructose in HFCS is bad, Fructose in fruit is good. Seed Oils are the biggest disrupter of metabolism, followed by processed sugar, and lastly grains (bread and rice, ect.)

[@summondominion]

100% im so tiredof hearing ppl talk about fructose...and say...fruit is bad for you...if ppl actually did any research...fruit itself has very little amounts of fructose in it.

[@Nick-fh9gy]

Gary Taubes has influenced Peter Attia, Gary has written several books about fat metabolism

[@macectoman]

Is there fructose in fruit?

[@loganw861]

In fruit it metabolized much differently that processed high fructose corn syrup. Fruit is healthy, maybe avoid all sugar and carbs for a while if your goal is to loose weight the fastest. Seed oils are the worst.

[@summondominion]

The dose of fructose in fruit is literally tiny...fruit is good for you. Anybody that says otherwise is dumb.

[@seanodanielsart]

Sure high fructose corn syrup is terrible. What about Fructose in fruit??

[@summondominion]

Do the research...there is very little fructose in fruit....youd have to eat fuck tons of fruit to get the ill effects. Having a few berries,Bananas and melons is good fir you. Breads grains and seed oils id stay away ftom

[@ondrej1893]

Gotta disagree here with the general “low carb dogma” choice of nutritional recommendations by doctor McGuff. One could just as easily make rough correlation with nationwide calorie intake and especially fat intake. Stephan Guyenet does that in his articles and books. After all, Americans eat 49% carbs and lean Kitava tribe members eat 70% carbs. So it’s not the carbs😛

[@blacky05hotmail]

His advice in the book is basically to eat whole foods and he specifically mentions industrial seed oils (fats) as a problem too. Your comment dismisses an argument that isn't his core position and not even really what he is talking about in this video.