Getting older without getting old - with Andrew Steele

[@TheRoyalInstitution]

As several of you pointed out, the original title of this video was inaccurate! Instead of 'Getting old without getting older', we've changed it to 'Getting older without getting old'. Apologies to Andrew Steele for getting it wrong - perhaps our brains need some of that anti-ageing science.

[@DrAndrewSteele]

Haha! No problem at all, thanks for fixing that and thanks for having me. :)

[@Jablicek]

@@DrAndrewSteele Thank you for the lecture!

[@DrAndrewSteele]

@@Jablicek Thank you for watching! :)

[@fragilechords5118]

Now just need to correct the spelling from ageing to aging.

[@bannor99]

Why wasn't the question & answer portion included?

[@boskovich]

I thought I accidentally switched playback to 2x but our man is wasting no TIME

[@maedilein6802]

I had to change playback to 75% because I can't seem to listen that quickly.

[@thedave1771]

I usually listen to most videos at 1.5% or 2%. This is excellent!

[@nHans]

​@@thedave1771 At 2% speed, a 1-hour video will take 50 hours!!! 🤣

[@joejones9520]

@@thedave1771 same

[@antondelacruz9362]

Hes worried bout how fast he is senescing.

[@germainenewman8526]

I was diagnosed with cancer age 44 and know many others who have been too at a relatively young age. I ate organic unprocessed food, exercised, mediated etc for many years before diagnosis. No family history, no genetic factors or risk factors. Environmental factors are huge, especially in hormone driven cancers. We need to clean up our toxic world to avoid cancer, it's not just ageing.

[@Shining-Star-]

We need to sort out the Constant spraying of heavy metals into our skies globally. Reduce the working week and have only one parent working. Back to basics and stop being selfish narcissists.

[@js4325]

I’m very curious about your diagnosis. I hope this question isn’t offensive to you, but was your cancer post CV and or vaccination possibly? I’ve been hearing of rapid cancer dx of younger people (30’s-40’s) after CV and the jab.

[@lyndacoops]

I have been fascinated by German New Medicine and the role of emotions and shock in causing cancer.

[@germainenewman8526]

@@js4325 it was pre Covid. I haven't had Covid or the jab. Yes I've heard the same thing re increased cancers. I'm not sure most people are open to that possibility yet though! Time will tell.

[@js4325]

@@germainenewman8526 thank you for the information!

[@ohitsjustsomeguy4156]

As someone who have followed and studied this topic for a couple of years I gotta hand it to this guy, he sure covered alot of ground in 1 talk. He really condensed alot into 1 hour. Good job.

[@lesjf8832]

"has followed", and I can tell you have studied absolutely nothing.

[@southernlights3682]

However, in terms of “climate change” this guy has no idea what he’s talking about, for if he would take a deep dive into the rabbit hole of climate science, he would discover it’s all one huge scam..

[@rajeshupadhyay5683]

Well said! I am also here to learn how to invest after listening to a lady on tv talk about the importance of investing and how she made 7 figure in 3 month, somehow the video taught me nothing and left me even more confused, I'm a newbie and I'm open to ideas on how to invest for retirement

[@lezliewhicker8450]

@@rajeshupadhyay5683 lookup Priscilla Dearmin-Turner, this is her name online, she's now the real investment prodigy since the crash and have help me recovered my loses

[@petermusa5396]

Despite the economic crisis and the rate of unemployment now is the best time to invest

[@michaelt2397]

At 70 +, I began paying more attention to the aging process. This has been a nice overview of the aging process and the research on slowing down the aging process. Seriously, reading up on aging on my own has been an uphill struggle. But I found that this video helped connect the dots for me in a clear manner. I really appreciate holding my hand as I navigated this complex process. And it does a very decent job in tackling tough social, economic and demographic issues. Keep it up guys, it has made a big difference for me in terms of how I live and move forward to the next couple of decades.

[@picturehangerfromsalzmanni956]

Micheal, read on Dvid Sinclairs work in Aus. Read on AUTOPHAGY and the bodies ability re WHITE CELL REPLACEMENT "technology". It does seem that one can "reduce" effects of aging by your genetic composition by 10/20 years. Natutal Health prinsiples are the key.

[@gore1089]

How about.. not dying.! Of course there's no stopping... Birth, old age, disease and death. Our individual karma has already dictated our future.. Some will get a life a little better.. Some a little worse. The only thing we can change is our individual karma.. That means escape the exhausting birth, death cycle.

[@douglasr.c.5622]

"Couple of decades"? Do you really want to live into your 90s ? Not me ! There are too many negative possibilities that come with aging at that level.

[@douglasr.c.5622]

@@gore1089 The problem is.... Karma doesn't exist 😭.

[@gore1089]

@@douglasr.c.5622 Like death.. But I bet if you ever get to that age.. or any age.. You'll put up just as much resistance as you do now or at any age. Why? Because it feels unnatural because it is.. Because we never die.. ever.!

[@gallbites8250]

Based on my life journey I notice that reaching 75 years birthday I reached my "end stop of life" and every extra day will be a gift!

[@extropiantranshuman]

mine will be 100

[@Native_love]

When I was a young man I worked at a Health food store. Over and over again I would meet these 80+ year old people (couples) who looked 40 maybe 50. I asked them what their secret was and they all said eating healthy foods in their natural form and taking some vitamins. They all took vitamin C and flaxseed and a few other antioxidant type vitamins. And they exercised daily in moderation. They looked and moved like athletic middle aged people.

[@yuliaschannel6288]

Flaxseed oil is useless we do not absorb it. You need real animal based omega 3 if you want to be healthy.

[@stretch4893]

Very true

[@leoandolino4668]

I would save your money and not buy the book, or trust "science" which exists to sell you a pill at a tremendous profit. Good clean food, herbal remedies, minerals, vitamins, and other supplements, rest, love, family, trust in the Lord make life worth living no matter how long you live and often does increase one's life span. Also avoid prescription drugs and over the counter medications. Over the long term they mess up your body.

[@askingwhy123]

Interesting observation, but there's something called "sampling bias." In this case, it seems reasonable to assume that patrons of a health food store, as a group, would be more interested in their health than a random person (as well as wealthier, more educated, etc ) and likely to eat the kind of whole foods sold at, well, health food stores. Their interest in health would also be plausibly make them more likely to take supplements. Finally, this biased (non-random) sample is also healthy enough to go shopping independently, despite their advanced age, something whole-food eating invalids aren't. Some things to consider when drawing conclusions about cause and effect.

[@vhawk1951kl]

and they6 were all wrong

[@nickisnyder3450]

Coming from NY, it is not often that I have to lower playback speed on speakers but listening to this guy at.75 made him a lot easier to understand.

[@Ntwadumela1]

Thank you for this comment. I am just learning English and thought I was the only one having trouble following this guy.

[@ericscaillet2232]

He does tend to speak fast ,probably does not want to waste time of his ageing audience🙃

[@anneku]

Absolutely fascinating! Thank you. Here are the time indicators for graphs I found interesting and useful 02:55 Graph - risk of death based on age 03:53 Graph - risk of death - mortality rate doubles after a certain age 6:00 Age-related diseases 6:22 Age-related conditions: loss of independence 6:51 Age-related issues that are serious as you get older 7:45 Chance of illness per year 8:14 add "chest infections" 8:54 Risk of death from corona virus 14:10 Infographic of ageing: leading cause of death is ageing 15:45 Hydra's risk of death - negligible senescence - How can we be more like the hydra 20:44 List of 10 cellular, biological drivers behind ageing 48:00 Population 52:30 Cost of chronic diseases

[@askingwhy123]

You are a hero! I can't believe I'm the first person to thank you. Thanks! 37:00 Metformin data and TAME trial

[@anneku]

@@askingwhy123 thanks! We index class video recordings regularly, so others can benefit also.

[@rodi2641]

Doing the gods work

[@tiffaniegrier4628]

Thank you!!!!

[@carolynleca1701]

M

[@MK-hh1vo]

Thanks for sharing this! This is research I've been following for years. I'm in my 60s with no medical ailments or prescriptions. I tell people I stay healthy and fit because I'm working on my *2nd 60 years* . They laugh but I'm serious, I plan to be around for a while and I'm not going to be decrepit and infirmed for my next go round.

[@___Anakin.Skywalker]

There's no sense in living that long if your poker stops working. You need a working poker to survive

[@MsElke11]

@@___Anakin.Skywalker there are many other things in life than Poking. Traveling with a loved one and just sharing a drink.

[@___Anakin.Skywalker]

@@MsElke11 but that's just hedonism

[@asdfafafdasfasdfs]

Hey people there's also learning about the universe and progressing the species. Stop being such primitive animals lol.

[@___Anakin.Skywalker]

@@asdfafafdasfasdfs bro we're not that smart. Leave that thing to the smart guys. Merry Christmas ⛄

[@markfomenko8873]

My body is almost 69 years old now. It's doing pretty well. Being very willful regarding what needs to be done to support this body as it ages helps. Doing a bit of research about death and persons who have been resuscitated after clinical death is interesting. Most recollections indicate dying is not so bad. Living well prior to death is my concern. Dr. Jamnadas has video content that's very useful. His talks for The Galen Foundation are my faves.

[@kajsa4448]

It was interesting until he started to talk about the Corona virus. The elder didn't get correct medication, they was isolated, wasn't allowed to see their relatives. They was just murdered!

[@rvonkesselstatt]

You say it... They were murdered...

[@mrbamfo5000]

Yeah, it was a super serial killer

[@mavrosyvannah]

All because China didn't want to pay their bill so got the US to use mail in election fraud to trick the President this world needed right now out of office. The left murders for vanity and power.

[@johnjennings9693]

I agree abolutely greetings,

[@marycoleman4301]

The truth about the massive fraud of cvd is thankfully coming out

[@IkeSpeaksUp]

When I shared this video with my friend, he said “i would rather live a long quality life than just a long life”. This is the reason this is going to take a very long time to get this information out.. people just skip over things like this.

[@MK-hh1vo]

🤔 But this lecture is about doing just what your friend suggested; improving the *quality* of an older/longer life. I think the word will get out quickly when people learn they don't *have* to become decrepit as they age!

[@jopmens6960]

This man talks so fast that i have gotten 5 weeks younger watching it

[@ExtantFrodo2]

Really? I was dissatisfied with his speed until I upped the playback to 1.25

[@DrAndrewSteele]

Haha glad to be of service!

[@slickwilly1099]

@@ExtantFrodo2 your Handel say's it all.

[@GenericCat]

@@ExtantFrodo2 200% here lol, it's actually really useful to be able to absorb information that quick, enabled it by listening to audio books a lot and learning other languages, increases the size of your audio processing capability

[@ExtantFrodo2]

@@GenericCat Just like speed reading one can exercise speed listening. It's just that in real life (IRL) one would have to push people to talk faster and that rarely works well so people don't exercise is. KZbin offers people a wonderful opportunity to rebuild some brain connections (in more ways than one).

[@kristinmyhr]

Amazing how he managed to put 3hrs (or more) of content into a 1hr lecture! I think this is the first time ever I’ve considered slowing a video down😅

[@Albertarocks]

Yes, he put 3 hrs. of content into a 1 hr. lecture but he also made his lecture a complete waste of time for most of the poor listeners in that audience. I actually watched the entire video on .75 of normal speed and it was perfect.

[@broadcasttttable]

I did....slowed it down to .75 speed. He talks too fast, hard to listen to, which is a shame because this is sea-change level stuff for the human consciousness.

[@jan_kisan]

finally someone who isn't rationalising this problem away, and persists with a clear and logical outlook. many thanks! looking forward to finding and reading the book too. i hope we won't die in another world war, and will live long enough for this man's aspirations to become reality. we need more people like him.

[@yellow01umrella]

Maybe a galactical war

[@davidthompson4934]

if they really want to cure the ageing process then the first thing they need to deal with is the chemical poisoning we are forced to live with in both our food, water, and environment.

[@futures2247]

well said - we are suffering with myriad cultural disorders that have been turned inside out into personal disorders for profit.

[@henrythegreatamerican8136]

Drink the blood of newborns. That's why republicans are against abortions. They need the newborn blood.

[@davidthompson4934]

Cultural disorders have little if anything to do with the fact that most, if not all the world's so - called clean drinking water is poisoned with toxic chemicals including fluoride which amongst other things is known to cause Cancer. Also, the food we eat is pumped full of toxic chemicals. The soil our food is grown in is also poisoned as is all the world's sea water and the very air we all breathe. Now it stands to reason that if everything that goes into our body is poisoned with toxins, then so too is our body also poisoned at the cellular level.

[@futures2247]

@@davidthompson4934 it would seem to me that those are all clear examples of cultural disorders in action.

[@TT-wu5zq]

Interesting stuff going on with microbiome studies.

[@jsunit5354]

I have three interesting individuals: A woman we know who is age 106, and has a mind of about age 50; a great-aunt (now gone) who was sharp and active until age 96; an uncle, now 95, who is razor sharp, socially active and in good health. I hope that I, now at 77, share some of their characteristics.

[@sundancer7381]

I know of a few people who are amazing in their 90's. Probably the most amazing is a woman who walks about 90 minutes a day - and exudes a magnetism that is electric. Hope I can do that!

[@ivyimogene]

If one is rich, living into old age is fine but not if one is poor.

[@flyjet787]

Without question the most exciting field in all biology - perhaps even in all of science today!

[@defaultdefault812]

No, you're just selfish and want it to apply to you.

[@eriksaari4430]

ai is far more important

[@tusharsiddharth6658]

For me its the search for extra terrestrial life

[@tomrees4812]

Climate change will ensure the planet will be uninhabitable by the end of the century so good luck.

[@badjohnnybgood9686]

This talk was amazingly informative. There are a many ethical questions not talked about. Statistics over the last 200 years on population growth, biodiversity decline in relation to the Industrial Age shows the world imbalance. Economics shouldn’t be first.

[@sunseeker4775]

I'm 75 and finally understand ageing and it's not what younger people think. Drugs won't fix it, but attitude, experience, environment and the state of mind can.

[@carollen5633]

Where will we get money for living longer? Is that new discovery only affordable for the elites? In this case they will run out of servants and slaves. Sorry to say. I've noticed many young people interested.

[@chan625]

What he should have hammered home in that last section is that anti-ageing efforts are not just about extending the life span, the main objective is to allow people to live more % of their lives without lingering problems forcing them to just countdown their last years. I don't there is any moral argument against that

[@stevesartain5804]

Productive lifespan, yes I agree humans seem frail and fragile to me, why is everyone getting so old and decrepit at such young ages and why is it that ten years later that hit model or actress looks like she aged 40 years ?

[@prendoso]

Wow - just stumbled on this. What a top guy - so logical and convincing. I'm in, let's live forever!

[@gmw3083]

Yeah make sure you get every vx they tell you to. Sign your own de@+h warrant.

[@DrAndrewSteele]

Thank you!!

[@Zen_Power]

I’m about to turn 40 and lived a very clean lifestyle. I feel great. I think a sleep deficit is a huge problem for a lot of people which contributes significantly to ageing.

[@MrBlaxjax]

@@captainkirk4271 gotta be said that soldiers are often necessarily sleep deprived. You are frequently required to stay up all night and sometimes you might get just a couple of hours sleep in a couple of days. So it's no wonder that soldiers are very happy to be allowed to sleep. Anyway, regardless, getting enough sleep is a priority. That's very true. One reason that exercise is important is that it facilitates proper sleep.

[@MrCmon113]

@@captainkirk4271 You can't be happy while asleep unless you are dreaming.

[@paulnolan4971]

They said I had to grow up... They didn't say I had to grow old.

[@EvaLasta]

You are young still lol to think 39 is somehow old is funny

[@Y2Kr4SHM4N]

If you maintain that to fifty, you’ll appear twenty years younger than your peers.

[@peterdavila3045]

Great video, thank you. I have been taking Metformin for a year now even though I don't have diabetes. I'm also taking Apigenin every day and Fisetin for 5 days each month. I can tell you that I feel so much better now than I have for the past few years. Also, it is subtle, but I do look younger today that I did a few years back. My neighbor and his wife mentioned that in passing during a conversation a few months back. After that, I told them about all this stuff about aging. I also happen to do intermittent fasting. I have been doing that for about 20 years now. I'm currently 67 years old. Let's live long enough to live healthy forever.

[@vibhaspalding6457]

Where do you get metformin from? In UK, it is not possible to get it over the counter. So I have berberine, instead. I believe it does the same function.

[@sweetlove332]

I don't think he delivered his presentation at such speed. I believe the posters of the video must've condensed it for whatever reason

[@akesha4138]

Reversing the again process takes a lot of knowledge, commitment and competence. I am 68 which shocks everyone who meets me. I still work like I am in my early 20's and can do hard physical labor if needed. You will need to do research in bio-chemistry, take a lot of supplements (as in by the handful daily) and keep a balanced life with lower stress. It can be done.

[@dingfeldersmurfalot4560]

Same here. I have a very physical job, am in my 60s, and people regularly say Iook at least 10 to 20 years younger. And that's now that my age is starting to show! People regularly have looked at me with astonishment regarding my age. Keeping fit and eating right goes a long way, even if you have other negative health aspects going on like stress, lack of sleep, etc etc name your problem or vice. I take a lot of supplements too. It makes a difference.

[@keisi1574]

@@dingfeldersmurfalot4560 Supplements shmupplements. You guys are so wrong. *No supplements needed* for health and TRUE longevity. It's absolutely irrefutably IMPOSSIBLE for you, or any human, to know the right amount of supplements to take. You only know enough to take to artificially/temporarily improve things.* That is IRREFUTABLE.

[@chickwithaguitar6876]

@@dingfeldersmurfalot4560 akesha4138 says he/she looks like they are in their early 20s. I would like to see a photo for proof.

[@Ladynipchick2]

@@chickwithaguitar6876 No. She said she works like she's in her early twenties. X

[@jjrr2273]

Right behind you - spent my youth involved in sports/just now learning tennis and have zero intention of quitting work/career - not in optimal physical shape yet have virtually eliminated all sources of major stress - yep happily single and its been a key gift!

[@riddlescom]

My goal is to live forever. So far so good . 100% successful.

[@kathleennorton2228]

Believe in Jesus!

[@paulskierski8271]

Eating a keto diet intermittent fasting i lost 35 pounds everybody says I look 10 years younger. I believe fasting and intermittent fasting are the keys is to age reversal to some extent

[@davidhogg1216]

Indeed this lecture went down the rabbit hole of drugs, drugs & more drugs. Scientists are so blinkered by their training to think that is the answer. Drugs are just crutches and do not tackle the essence of ageing.

[@JCX-9]

Your sleep is just as important. It’s during the sleep when your body repairs itself.

[@jfo3000]

And just eating less in general. So much of our life force goes into digestion.

[@bookzdotmedia]

Same here,, keto and 14 hours fasting daily

[@bookzdotmedia]

@@JCX-9 sleep is fasting

[@mariabarrientos-quincy868]

Absent from the body, perseny with the Lord! Nothing can beat this!!!

[@mariabarrientos-quincy868]

ABSENT FROM THE BODY, PRESENT WITH THE LORD! NOTHING CAN BEAT THIS!

[@marktoovey1318]

I'd heard about one or two of the possibilities in reversing the aging process over the past few years and was wondering how the various things in trial were going, but obviously wasn't aware of how many different areas of research there were that are likely to now to be developing ways to treat each specific symptom, and it is very nice to see how excited Andrew is about the possible near future advancements. Thanks so much to him and The Royal Institution for sharing this information, he is very articulate, easy to watch, and his excitement is contagious. I just hope that people will start donating to research into curing ageing, rather than donating so many billions to curing each of it's individual symptoms! There's another few trillion dollars into the world economies once/if a cure for ageing can one day be found. 🙏✌

[@t.a.3191]

"cure for aging"? Ageing is a natural process, unless you meant abnormal ageing.

[@questioneverything594]

@@t.a.3191 Actually that's not true. "Aging" is itself a disease. It is a complex set of processes and changes that make the body and all of its components deteriorate.

[@manzoora8101]

I worked in a grocery store for a long time, and I noticed that elderly people would always buy fruits and vegetables. Besides that they would buy other products that were old brands which had simple ingredients or maybe they loved them since childhood.

[@fabiocaetanofigueiredo1353]

@moi2833 😂

[@annkristinbarnes4596]

A good rule for staying healthy is to only eat food which does not come with a long list of unpronouncable ingredients.

[@andreafox7267]

I love watching these RI presentations. Andrew Steele is captivating here. A fascinating subject. 👏🏼

[@spaceted3977]

I'm 68 yrs old and of course as a Pensioner, I have 2 Racing Motorbikes, and a third motorbike to take my dogs in a cage on the back !!!! I have the usual hobbies at my age, X Box, Gaming Pc with Flight Simulators and Battle Simulators !!! I listen to German Dance Music on my Internet Radio !!! I have loads of tools and equipment to fix anything !!! I am interested in Quantum Physics, Black Holes, Quasars, Gamma Ray Bursts and History. I cook whatever I want from scratch. I can cook Chinese, Curry, Pasta, Southern Fried Chicken etc !!! I don't drink, don't smoke, eat very good organic food, never had cancer etc.!!! I get bored with people and I don't socialise much now !!! So I don't catch viruses !!! I am not married, have no children and live in my own place with my 2 dogs !!!! I am very happy and am enjoying every day of my life. !!!! I don't look my age either. !!!!! I drive racing cars and Racing Motorbikes on my Isle of Man Simulators. My mind is Sharp and I can take in loads of information !!! I love learning new stuff. All my friends of my age are going senile. I am not very athletic, but I have a lot to do to live alone and have a large garden !!! I have never been in Hospital for any iIlness or injuries etc. !!!!

[@dcgallin]

And you have a lot of time to comment here..

[@nickji]

Space Ted : So what? Do you think all that makes you special? I'm ten years older than you, and totally healthy, but I know I'll die sometime in the probably not too distant future. And that's fine with me, we're not designed to live forever.

[@georgemouchaty1104]

Mate but having children is also a gift from God and from Love, pure love is veryyyy healthy indeed. Take care

[@MrBDezno]

My grandfather died at 81 in early 1990's. His uncles, so a generation before him, lived to be 102 & 103. *These were men born in the 1800's - no nursing homes etc...

[@puppy1584]

I found the guy speaking too fast for me…yeah, I’m aging. So I slowed him down…perfect. Now my old brain can take in what he’s saying - and I might even understand it too.

[@mattasrinivasmohan5808]

You are right. He talks too fast making one lose interest in what he is saying.

[@sandywhite1550]

I’m old and didn’t find it hard to keep up with the talk. Although he talked fast and excitedly. I’ve noticed my problem is being able to read as fast as I once did when younger. I guess my brain isn’t what it used to be.

[@MrSreeramIII]

😂

[@cvetelingeorgiev1527]

That's a side effect of taking anti-age pills - they make you talk with the speed of a young laboratory mouse.

[@theon9575]

Haha. I'm old, likely older than you, and I tend to blame everything on my old age, too. When I tell my physician I'm forgetting stuff, am I going senile? He wryly says, "Oh, did you never forget anything when you were young?" This excellent lecturer DOES speak much too fast. Many but not all Comments here say so. And it's not all about your age 😂 I'm a retired professor and I can confidently tell you that it would challenge the listening & concentration skills of most 25 year old students. Take heart 😂

[@eu29lex16]

Ageing is basically a health problem, your body is literally slowly deteriorating and as it grows older you health becomes weaker as every bit of tissue starts becoming more and more unresponsive. It can be only treated by continuously improving your health.

[@vhawk1951kl]

Is not the truth of the matter that from the moment that men (human beings) are born, or first draw breath, they embark upon a process identical in every respect to either jumping or being pushed from a very high place, which can only possibly have one result or consequence? What the speaker seems to be contemplating is that it is possible to commence or start that process of falling *without* eventually coming into contact the ground or whatever is adamant at high speed, or that it is or might be, possible to go in for falling *without* landing on the ground. Is it not exactly correct state that there is absolutely nothing that anyone might try after entering the process of life or falling that can possibly alter that inexorable consequences or results of falling which started from the moment that you either jumped or were pushed? Is it not true to say that for all practical purposes, given that jumping or being pushed, or living can only have one possible outcome jumping or falling or living are in every possible respect identical to hitting the ground? - Because one is the inescapable consequence of the other because that was a certainty from the moment that you were born, first drew breath, jumped, or were pushed, or were born, for all practical purposes given that the outcome of jumping is hitting the ground. Furthermore it strikes me that while you are alive or falling, no amount of worrying or being afraid and no amount of doing anything can possibly affect the inescapable consequence or outcome. Why would anyone be frightened something that they have never experienced? Is it not true to say that no amount of fear or care can possibly alter the inevitable outcome of jumping or being pushed or living? - Do you not hit the ground the very second you jump or are born or commence what is called living which in point of fact and reality(whatever that might be) that it can only possibly have one *absolutely certain* outcome unless of course you happen have a note from your mummy saying that diddums is excused gravity, so the title the piece is best rephrased as “how to jump or fall/jump from a higher place without hitting the ground which is identical to saying: “how to go swimming without getting wet” Thus birth is jumping, and living is falling. Right now dear reader you and I are rather like the man that jumps from the top of a very high building of say, two hundred storeys and going by an open window on the 50th floor and saying to whoever happens to be looking out of the window: “so far so good.” That being the case the title of the piece is little more than: “how to jump from the top of a skyscraper without actually hitting the ground.” I rather suppose that there is a word or someone that supposes or imagines that that is possible given that for practical purposes jumping or falling and landing, are one and the same thing, or some might suggest that is possible to fall more slowly and that to them, they appear to be falling so slowly that they may suppose that they will never get the ground, and I also suppose there is a word for someone like that. You and I, dear reader are falling at this very moment, are we not? Do you suppose that there is *anything* that you and I can possibly do that can materially alter the inevitable outcome of jumping or being pushed, or living, or falling? Do you perhaps suppose that it is possible to fall*Up*?

[@eu29lex16]

@@vhawk1951kl "Do you perhaps suppose that it is possible to fall*Up*?"- You can't fall up, you can only rise up after you fell. Basically, only revival in another body can fix this .The body always seems to suffer some damage because substances have a limit to how well they can keep our genes. And I think there are some other reasons.

[@ericscaillet2232]

@@eu29lex16 close to a good perception but wrong,yet yes but that is not the answer.

[@eu29lex16]

@@ericscaillet2232 How is it not ? Nature has entropy(it's dynamic/active) genes can't keep up with it forever, they eventually fail(even if healthy 0 it's just that you can make them last longer(be longevive).It seems to be the case and I see no way to change this, just prolong it.

[@johnjennings9693]

@@eu29lex16 maybe grab something on the way down to hold you,

[@willboudreau1187]

I'm going to live forever. So far, so good.

[@DiowE]

I thought you were a chad, but you comes out to be a gigachad. [DiowE]

[@yankee2666]

There’s a great little book on natural healing written by an older man who cured himself of a number of maladies without medical intervention, called My Physician, Myself. I read it a couple of years ago but lost my copy. I’m going to Amazon right now to order one and be more careful with it. It’s more than worth the read. You might look into the work of Luigi Cornaro, a Venetian nobleman who lived to be 102.

[@DiowE]

@@yankee2666 Will definitely read this book. [DiowE]

[@thomasburckardt2950]

What a brilliant presentation … i enjoyed every moment … thank you …

[@rosenjoroge9373]

A learned gentleman clearly passionate about his work. :)

[@centurionstrengthandfitnes3694]

Clear, concise, comprehensive and profound. Incredible talk and far, far more people should see it.

[@zooblestyx]

I like to tell younger people to be healthy and live long lives, to live to 120 if they can, to live long and rewarding lives, but along the way, to avoid aging, because, brother, aging sucks.

[@patriot20000]

I think if you take the exit off I-95 Before you hit Florida you can avoid aging. .

[@zooblestyx]

​@@patriot20000 You are most likely right, but at the same time, I feel that driving from NH, just the stress of trying to survive all the on and off ramps around Boston would age me about 20 years.

[@ethan-loves]

Both fascinating and exciting. Good on him for highlighting the hope and varied societal benefits of treating aging. There will be unforeseen consequences, but nothing we can't handle.

[@onebylandtwoifbysearunifby5475]

He misrepresented some of that though. Look up a chart showing global population growth since 1800 or even 1900 to current, not the fake one he used for bias purposes. There would be more people added by his plan than the entire global population in 1950. His "only 16%" is 2 BILLION more people. (Plus 9 million people starve to death every year NOW. That's 250,000 just today. 250,000 tomorrow. And every day after. There's no place for misinformation in science.

[@DrAndrewSteele]

Thanks! And I totally agree-bring on the challenges and the longer, healthier lives. :)

[@onebylandtwoifbysearunifby5475]

@dražen g That's the reality, yes. For every 10 years the rich extend their life a child would die. 9 million starve to death each year as it is. Where is all the extra food going to magically come from? Deforestation? Chemical fertilizers made from fossil fuels? But the rich don't care about the 250,000 people who starved to death today. But they are suddenly going to care if they get to live to 200 through? Nonsense. Total nonsense. Dystopian nightmare and infanticide. What selfish monsters have humans become?

[@victorycall]

@dražen g "strain it would put on pension system": if people are staying healthy and robust why should they retire in their 60s? Why wouldn't they continue to stay employed into their 100s (or 200s...)? The sad answer is that a lot of people are fundamentally unhappy with their jobs. Looking forward to being able to give up employment in their 60s is what keeps them going day to day. The requirement for most people to labor in an unfulfilling way for most of their lives is a much more serious societal issue than ageing. The lack of resources would also be a very serious challenge with increased population due to extended lifespan, but it's already a very serious challenge with people dying on average in their 70s. These don't have to be either/or, all or nothing propositions. As a species we can learn to extend our lifespan to the fullest, utilize resources wisely, eliminate human abuses of each other, etc., simultaneously.

[@uvwuvw-ol3fg]

Seems like inherent optimism bias and terror management theory will always help regardless of ideologies such as antinatalism based on consent and efilism.

[@abdelmanzalawi8957]

The new global theme: Live forever, or die trying.

[@colorpg152]

if only, the deathism is still rampart

[@abdelmanzalawi8957]

@@colorpg152 don't bother, the love of life is rather intrinsic in our species. They yearn toward survival.

[@colorpg152]

@@abdelmanzalawi8957 indeed but in order to cope with the fear of death they will convince themselves of the craziest lies like telling themselves that dying is good or needed, and that is without the religious beliefs, imagine what those hyper religious countries like islam will says when they find out death is not a certainty

[@abdelmanzalawi8957]

@@colorpg152 I guess religion will become pointless if we achieve life with unnecessary death. But even the hyper religious people can be changed. If not, their children must change eventually. Science is not the end of religion though, the end of religion is "irrelevance".

[@FelixTweezer]

Thats the spirit!

[@wendywhite2642]

When we live in a world where unseen powers are directing people to go against their own best interests with disinformation, what force do you think there is to make people live longer? Those unseen forces don't want us to live longer because we cost a lot of money to keep alive in retirement. I love the idea of these wonderful studies, but it's just not in the interest of authority to keep us alive longer.

[@DavitBarbakadze]

Please bring this man back one more time and force him to elaborate on the rest of ageing hallmarks.

[@Abitibidoug]

Interesting talk on the subject of aging. It’s primarily about anti-aging drugs that will be available in the future. If that’s the case, and they’re affordable, I’ll try it. In the time being, it makes sense to take good care of yourself and stay active to slow down the aging process as much as possible. Now for my story. As a teenager and preteen kid I was one of those wimpy weakling types, largely useless at sports and school physical education class. Fast forward to the present I’m 61 years old, healthy and quite fit, and from what others have told me I look about 8 years younger than my actual age. Why? What happened? It’s because I smartened up, have taken decent care of my health, and keep active, ignoring all those ageisms that someone my age shouldn’t be doing the things I do like mountain biking. If I can do it, so can anyone else. I recently saw a video about a woman 73 year old mountain biking down steep slopes in British Columbia. Also I see Paul McCartney is still rocking at 80 years old and last but not least I saw a clip on TV of a 100 year old man still driving the tractor and working his farm near Teeswater, Ontario. See what happens when you stay active?

[@SmilaZ]

try the japanese science of refined ways of hydrogen (natural, no pills).

[@kevincuevas8877]

A caveat worth mentioning is there is such a thing as overtraining and it is quite debilitating. An active lifestyle needs more sleep to repair and build muscle. More to the point, most people are not mesomorphs, so attenuate your expectations accordingly. More breathing also means more oxidative stress and cell cycling, and not all activities are created equal. Running a marathon in a smoggy trafficked road probably isnt as good for you as doing cross country in a forest or beach.

[@SmilaZ]

@@kevincuevas8877 the answer to all that is, that we need more (but pure) hydrogen. Japanese science is ahead of everyone with this and a few other things. AND IT IS anti aging and age reversing. And the body finally gets to demonstrate to us some of all the healing and restoring, cleansing and detoxing that it can do. Purity of the Hydrogen is the key, which is also why its officially called Holy Hydrogen (because Holy means pure). Yeah look into it. When it comes to thoroughness and perfection, nobody beats the Japanese. They will wear themselves out to death to get things perfectly right.

[@Abitibidoug]

@@kevincuevas8877 I believe you about overtraining, it makes sense. However, in my case there are lower energy days as well as high energy ones. All in balance.

[@mechannel7046]

Great to know you are fit and healthy. Can you share specifically what you have done to transform your health?

[@toni4729]

I'll say what no one else has said: You're very easy to understand and thanks.

[@captainsukycannon1167]

For decades, when people ask my age, I always say ageless. This came from studying metaphysics, and anthropology. Our cultures assign certain behaviors and have definite expectations of each age. I decided to trick my mind, which is why I don’t announce my age.. it’s not vanity.

[@captainsukycannon1167]

@Nero Machiavelli haha

[@DiamondlightT]

That is super clever..im stealing that. Thank you

[@binathere2574]

If you do announce your age, you are immediately judged.

[@binathere2574]

@Nero Machiavelli your time is coming.

[@binathere2574]

@Nero Machiavelli bahaha. Boom!

[@Flamelilyful]

My hearing has just had the best marathon ever and the content was excellent.

[@bigred8438]

That is so true. We could all die right now and would never get older.

[@mrbillhicks]

I recall reading somewhere that it's all linked with heart beat.... An Elephant heart will beat a certain amount of times over the course of it's life, and a Canary's heart will beat around the same amount of times but over a much shorter life span.... So there

[@henryjraymondiii961]

Neil Armstrong thought people would probably only have a certain amount of allotted heartbeats in a lifetime. However, I don't know how many heart beats he did on the Moon's surface in 1/6 G. Maybe set and setting has something to say during the "course" of a "life".

[@brucezar2202]

Great update on the current state of research aimed at curing the worst of all diseases, human biological aging.

[@jmdsservantofgod8405]

Well Andrew it’s so obvious that you are very excited about this!

[@uffa00001]

Serious fasting (2 weeks at a time or more, only water) is the medicine we already have. Fasting "eats" senescent cells and "rejuvenates". I fasted two times (29 days and 14 days), and both times my relatives told me I "looked younger", and I felt younger, too. I am planning to fast once a year for 14 days for the rest of my life, if circumstances allow for it.

[@ccdg1066]

Do you know of any scientifically conducted experiments that have followed people to their end of life that would tend to strongly support this hypothesis? It's such a complex environment in the varied regions of the planet with so many varied living conditions it might take a long time to see real conclusive evidence (jmo). Thanks :)

[@uffa00001]

@@ccdg1066 There are things that do not lend themselves to "scientifically conducted experiments". You cannot have 30.000 persons fasting for two weeks every year of their life. People tend to be obsessed by eating in general, and "compliance" would be very difficult to verify. "Scientifically conducted experiments" are useful but medicine is larger than that. If you only stick to SCE you would end up denying that psychology is useful or that having a sporty lifestyle improves your health. If you do something and you feel better, that for me is better proof than any SCE. What matter to me is my health and not SCE.

[@xs3282]

@@ccdg1066 so human beings have been around for hundreds of thousands of years, do you think they all ate three meals a day in all that time?, or even early humanoids, they would have eaten even less,….fasting has been adapted over hundreds of thousands of years by the human body to rid itself of toxins and to renew itself on a cellular level through autophogy, there is your answer thank you very much

[@ccdg1066]

@@xs3282 I asked a question but you seem not to have read that. Also, never talked about 3 meals a day. Human lifespans have been increasing, and with better diet and lifestyle It might continue, and with less war, disease, etc. My question was about scientific study of the efficacy of fasting... is there evidence? Your idea may prove to be correct but I was looking for more than your opinion. :)😀

[@Zill7711]

Look up Dr Jason Fung and Dr Paul Mason on KZbin as they present the science on fasting really well, in my opinion. I am hooked on their lectures. Anecdotally I have been eating less meals a day, going with out food for 16- 20 hours most days and sometimes I have done two or three day fasts and I do feel it has done me lots of good. This is combined with eating less carbohydrates. I sleep better, lost a bit of weight, have loads of energy all day. Noticeably better than before I started fasting.

[@Ocean-Mariner]

This man is defying ageing by speaking really really really quickly..

[@OperationDarkside]

Unrelated to all the moral issues and monetary benefits, I see a huge potential in academics. Usually aging puts a massive damper on your academic career. As I have taught programming to 13 and 40 year olds alike, you can clearly see the slowdown with age. Programming is a especially good indicator since it deviates from almost everything you learn in school and daily life. You really need a flexible mind and children are very good at that. If you could bring just a little bit of that flexibility and curiosity back to a 60 year old researcher, we could narrow the gap to the next breakthrough in anything basically.

[@Grizabeebles]

I believe you are underestimating the importance "forgetting" plays on the development of new theories. I strongly suggest you watch Richard Feynman's lectures on physics from the 1960s. There's a particular moment where one of the professors in the audience tries to defend "classical optics" - only for Feynman to shoot him down in spectacular fashion based on recent experiments confirming certain predictions provided by quantum-mechanics. We need to face facts here - a human brain with a Ph.D already takes an average of 31 years to build. By any reasonable standard, it's already approaching mid-life and becoming obsolete as is. Asking a brain that's been specializing on one specific subset of problems for 30 years to keep producing discoveries when its 30 years out of date with much of its own field let alone applicable discoveries from every other field is almost pointless. It's not about the quality of the individual brain, it's about the quality of the information stored within.

[@ts4686]

OP and Grizzabeebles you both made such interesting points. From my own personal thoughts, I've always thought that the work systems, mostly globally, but especially in the west, and in countries that adopt western ways, are deeply flawed in how only a very very specific and small demographic is considered by society of greatest value, contributions worthy and capable to being a productive member of society. Work structures are created so that anybody older isn't viewed as valuable, and are unashamedly rejected. No matter the different ways the human mind scientifically computes as it lives, we still acquire wisdom through experiences and an endless degree of other things, something a young person would never be able to contribute with. That said youth IS also very valuable. We just reject incredible productivity, their guidance and personal historical information from our elders, solely due to some baffling obsession with youth. When I speak to older people, I'm blown away by their stories, every single time, by the way they think and how they perceive life. They're treasure troves, and should be a part of society/life as such.

[@Grizabeebles]

@@ts4686 -- This is just my opinion, but have you ever noticed how people of different ages search for missing objects? Children under a certain age tend to run from room to room randomly, teenagers and adults in their 20s start tending toward retracing their steps and doing systematic searches. And people above a certain age tend to shout instructions based on personal experience and historical patterns without getting out of their chairs. There's also the phenomena of people age 30+ starting to walk past the object they're looking for multiple times because they're expecting to see the object in a familiar place or see the object from a particular angle. Adults who don't have children often forget to check to see if an object is buried under other objects, etc. I suspect humans evolved under conditions where people of a variety of ages worked together to solve problems. As such, brains of different ages are more sensitive to different types of patterns and different types of problem-solving. But how is that supposed to be leveraged when it comes to problems like solving string theory or marine rescue or designing skyscrapers? There's a certain minimum of technical knowledge that takes decades to learn or extreme safety risks that make bringing children to the problem *more* troublesome rather than less. What I'm suggesting is that the same probably holds true for the other age-related brain development cohorts. We as a species have generally let our social and economic systems stratify based on arbitrary lines. But age isn't arbitrary - it *HAS* consistent and measurable effects on the way a person thinks. It is my belief that there are just some problems that an 8 year-old is better suited to solve than than a 38 year-old or an 83 year-old. A society composed of only one type of mind only produces one type of solution. A society mostly composed of old minds, for example, results in nothing but a lot of shouting and no actual movement.

[@ts4686]

@@Grizabeebles I think you perfectly summed it up in paragraph 3 and in the last one. We are better suited at becoming successful beings as community and in unity, than the way we are now fragmented, divided and separated, based on producing endless profits in an unsustainable system. These systems are not in sync with humans, nor are they sensitive to our rhthyms, potential or well being. They're merely there to generate more more more profit. Profit based in yet another theoretical unsustainable system, benefitting only a few. The fields you mentioned of engineering, science and architecture are a mere few of massively vast job descriptions, but even in the jobs you wrote of, they've effectively proven that getting children and older people in on idea development, has shown to be beneficial, exactly due to that one category of minds can't produce enough diversity of ideas and productivity. I'm not saying hire a child to calculate plan safety methods for a skyscraper construction, but I solidly believe in a variety of minds for the efficacy of the most successful societies.

[@Grizabeebles]

@@ts4686 -- I agree. Please bear in mind that as life-spans grow longer the proportion of the population with an "elder" mindset will grow far above historical norms and unless preventative action is taken, society will naturally shift exclusively toward the primary "elder" problem solving method - yelling at young people. Already, the Japanese society seems to be on the verge of a critical number of young workers getting so frustrated with having their voices suppressed by an aging generation that they are choosing to eschew traditional work and material possessions and are simply waiting until enough of the elderly population dies off for political and economic reform to be possible. This phenomenon manifests in many ways and is known by many names - "lying flat", "parasite singles", NEETs, Hikiomori, etc. What else are young people supposed to do in a society which either hires you straight out of school or requires 5+ years of experience? All they *can* do is form their own insular subcultures and parallel societies their *WHOLE* lives.

[@lorrygeewhizzbang9521]

When I started "restudying" biology as an adult many pennies finally dropped compared to what I learned in school, to break it down I realized yes you are literally what you eat and more on the philosophical side of things, yes we really are all one. It made me think about ageing and what those implications would be if we lasted even a decade longer. If everyone had the more reasonable life span of 100 years instead of maybe making it to our 80s/90s I think it may have the opposite effect on the population. I think most species only breed out of nessecessity and lack of time. We "know" we only have so long to have a family and on an emotional level it may be to replace the family already lost etc. But what if we have more time? That might change. Also on the most selfish side some people try to live their youthful dreams through their kids, again what if we have more time to realise those dreams for ourselves? As far as America and where it throws money, I don't think all the Healthcare companies would let money go to that research when they make so much from diseases and suffering. Vicious cycle.

[@jasonlionbar1911]

You Are watt you think '' not watt you eat . And A little intermittent fasting helps one to see the real evil that's currently running this world ''.and yes they are not at one with us that's another one off there lies about being watt you eat ? I had lamb the other day and I'm not running and springing around saying Bhaaaaaaa.? Lol you Are watt you think .👍🤔''

[@lorrygeewhizzbang9521]

@@jasonlionbar1911 I think you can't spell, and if you can't spell well then I hardly expect you to understand mitochondria or the inner workings of a cell.

[@clownssschwab6394]

No proven correlation between spelling and grasping of concepts. .... example - would a car mechanic that fixed your car's spelling issues mean he didn't fix your car?? You should add majority of young people

[@clownssschwab6394]

You should concentrate on the intentional food/fuel shortages . ... your data has been damaged with that jbbi jabba ... now starvation. ..

[@daveog182]

Guys, these issues go beyond grammar or comprehension. We are all connected 🙏 ❤. And it would be great to observe cause of effect. The human race is being programmed over millenias , however peopple are waking up.@lorry gee. I deliberately misspelled a word 😆 hope you don't tell me off..... One love ❤ all stay well stay healthy.

[@riccardo50001]

A fascinating topic, I will continue to follow this topic, since I am 77 and my body is definitely expressing that reality; monthly eye injections for wet macular degeneration, skin becoming saggier, surgery to remove a bone in my wrist to stop pain. However, as I look around myself, I'm often shocked how much slower this process is occurring in my physical appearance. When I go to senior events, most people look 30-40 older than myself. I'll keep watching and learning and I wish this guy could speak quite a bit more slowly, but that probably wouldn't be possible since his mind is delving into such complex topics.

[@SeethingSimp]

If that's you in your videos, you do look a lot younger than 77. Any advice?

[@morespinach9832]

Despite a fast talking an hour for this! Would love a 5 min summary version

[@knightgern]

Who want to live long ? Who want to watch the same movie everyday ?

[@nortonkelly8460]

Ave age of death before jab rollout was over 82 for covid, his graph is wrong

[@eleewilsonjrcosmosart]

Very interesting presentation, however Andrew‘s advice to switch to a more plant-based diet has no basis in science. This is not about mTOR; it is about eating an ancestral/Paleo/animal-based natural whole foods diet, which is what we are genetically designed to thrive on eating.

[@Tresorthas]

Evolution gets a lot of things wrong, especially if it has no way of preparing for it. Also, the diet of the earliest hominins was probably somewhat similar to the diet of modern chimpanzees: omnivorous, including large quantities of fruit, leaves, flowers, bark, insects. Meat only became dominant as the hunting tools evolved, which made it possible to hunt larger prey (to near, or total extinction). And then agriculture brought us back to plants, mostly, until the domestication of certain animals.

[@antonystringfellow5152]

Excellent talk but just one minor point to add: For "evolution" read "natural selection". That's really what he means here. Quite common but important to differentiate. "evolution" means a gradual change and can apply to just about anything, from life to consumer products. "natural selection" is a type of evolution but one that is determined by a combination of chance and environment (simple in principle and without a designer). In reality, evolution by natural selection is incredibly complex but that complexity arises from the huge number of variables involved, not from the concept itself, which is actually pretty simple.

[@gallbites8250]

On my body I have 3 ages: 1. My real age soon: 75 years, 2. My brain age now: 35 years and 3. My life experience based on my life journey experience: 120 years.

[@davidlittlefield2483]

Thanks for all your great research! Can you guys please hurry up with the cure for aging? I'm on the steep slope of the curve and I'm afraid of heights. I hope you find the cure in time for me. I'd hate to be late for that train.

[@vhawk1951kl]

Is not the truth of the matter that from the moment that men (human beings) are born, or first draw breath, they embark upon a process identical in every respect to either jumping or being pushed from a very high place, which can only possibly have one result or consequence? What the speaker seems to be contemplating is that it is possible to commence or start that process of falling *without* eventually coming into contact the ground or whatever is adamant at high speed, or that is or might be, possible to go in for falling *without* landing on the ground. Is it not exactly correct state that there is absolutely *nothing* that anyone might try after entering the process of life or falling that can possibly alter that inexorable consequences or results of falling which started from the remote that you either jumped or were pushed? Is it not true to say that for all practical purposes, given that jumping or being pushed, or living can only have one possible outcome jumping or falling or living are in every possible respect identical to hitting the ground?= Because one is the inescapable consequence of the other because that was a *certainty* from the moment that you were born, first drew breath, jumped, or were pushed, or were born, for all practical purposes given that the outcome of jumping is hitting the ground. Furthermore it strikes me that while you are alive or falling, no amount of worrying or being afraid and no amount of doing anything can possibly affect the inescapable consequence or outcome. Why would anyone be frightened something that they have never experienced? Is it not true to say that no amount of fear or care can possibly alter the inevitable outcome of jumping or being pushed or living? - Do you not hit the ground the very second you jump or are born or commence what is called living which in point of fact and reality(whatever that might be) that it can only possibly have one *absolutely certain* outcome unless of course you happen have a note from your mummy saying that diddums is excused gravity, so the title the piece is best rephrased as “how to jump or fall/jump from a higher place without hitting the ground which is identical to saying: “how to go swimming without getting wet” Thus birth is jumping, and living is falling. Right now dear reader you and I are rather like the man that jumps from the top of a very high building of say, two hundred storeys and going by an open window on the 50th floor and saying to whoever happens to be looking out of the window: “so far so good.” That being the case the title of the piece is little more than: “how to jump from the top of a skyscraper without actually hitting the ground.” I rather suppose that there is a word or someone that supposes or imagines that that is possible given that for practical purposes jumping or falling and landing, are one and the same thing, or some might suggest that is possible to fall more slowly and that to them, they appear to be falling so slowly that they may suppose that they will never get the ground, and I also suppose there is a word for someone like that. You and I, dear reader are falling at this very moment, are we not? Do you suppose that there is *anything* that you and I can possibly do that can materially alter the inevitable outcome of jumping or being pushed, or living, or falling? Do you perhaps suppose that it is possible to fall*Up*?

[@jamesallan1883]

@@vhawk1951kl Cycle of life vs slope. Start to die the day we're born.

[@vhawk1951kl]

@@jamesallan1883 self-evidently, although I cannot speak for others whose experiences I cannot experience. To quote from the TS Eliot poem: "in my end is my beginning".

[@luismiguelmartinezsanchez4069]

@@jamesallan1883 no es frecuente

[@donaldevanshennings7732]

It is already possible to minimise all the diseases mentioned and thus age considerably more healthily by changing our diet to one that minimises carbohydrate, especially refined sugars. All those diseases and more in most people are due to our bodies inability to deal with the high levels of blood glucose and fructose in the modern western diet. The damage caused by this takes years to accrue but accelerates with increased dose. This increased dose is why we are now seeing children who are obese and diabetic after consuming this hyperpaletable and cheap food from a young age. We only need look back 60 years to see a time when these diseases were rare. This dietary change would also save our health services billions.

[@DailyPaintworks]

This is why Metformin has anti-aging effects - because it helps reduce blood glucose levels. It is odd that this video doesn't mention at all the role glucose has in disease and aging, in great part through the glycation of proteins. I think it is because a high carb plant based diet is accepted a priori as the optimal diet for humans, so it is never considered a candidate for causing illness and accelerated aging.

[@DrAndrewSteele]

@@DailyPaintworks I didn’t go into the role of glucose because of time constraints! There’s plenty of info about glycation of proteins in my book. :)

[@dcgallin]

@@DailyPaintworks it's because they want sell Metformin as a cure instead of preventing high glucose levels?

[@julian.kollataj]

0.75x video speed seems to be an ideal speed that makes Andrew’s presentation well worth a listen to, for me anyways. As for ageing, I would want to know what percentage of a population doesn’t experience those four key diseases/illnesses, globally, and by country… 🤔 and what is the cost to society and the ecology with that group of people…?

[@Ana-bw7gm]

Excellent. I have never seen/heard anyone speaking so fast, had to stop and go back to hear things again.

[@LuciLaird]

My parents lived actively to the age of 95. I plan on the same

[@steve4633]

I'm about to turn 48 and feel like I did when I was a teenager and probably just as for as well. I love weight training and I'll never stop doing weight training either.

[@metamind095]

Trust me you do not. Cognitive and hedonic aging do happen very gradually this inturn makes you not notice the decline that, without shadow of the doubt, happened!

[@imyourdoctor4799]

TRT 💪

[@AP-nj1mr]

I am glad you are feeling well. The sad fact remains that our physiological reserves plummet with age even if we still feel great. That is why this sort of research is so relevant.

[@glowinthedark9082]

that's good. I'm really hating my body change and making it feel different. I wanna feel the same everyday

[@Ryo-sd9rx]

Slow down just a little and you will be received by the audience a little more. Great presentation though, very passionate about your work which is a beautiful thing.

[@Abitibidoug]

I'm duly impressed at how he gets the information out efficiently and expediently without any oms or long annoying pauses and I absolutely LOVE him for it. Awesome work Andrew, keep it up!

[@Mrs.TJTaylor]

Change the playback speed to 75%

[@madyak222]

Hasn't fasting been shown to increase autophagy to remove senescent cells?

[@andreahodson7031]

autophagy increases as the fast does. at 72 hrs and on it creates new stem cells

[@Heresheis0818]

You could be old but still manage to maintain organs young and fresh. The trickiest part is to regulate the hormones receptors of which control the blood flow degrading the vascular system every year. # How to trick the system to repair takes years to perfect the formulas # blood types # innate counts

[@micmacha]

Computational biology is a gift. I will be very fortunate if I can live like I'm in my 20s while in my 90s.

[@TinyTexasHousesPSO]

Yikes, coming up on 67 and realizing 5 more years is really close, I am glad I took to Youthing at 55 to prepare so as to have fun during the best years, our prime, 66-78 if we do it right. I am going for it. Hope you do to. Salvage the best of our past, create an incredible future, perspicuity is the key.

[@chrishamberg8028]

Our species is insane, if we don't devote every available resource to "curing" aging.

[@wendycarter5718]

If we “cure” aging we will also have to “cure” breeding !!! We already have far too many humans on this planet !

[@SusannahWitriol]

It’s fascinating stuff, and I think I agree with the moral conclusions that Andrew comes to. But there is a very sad side effect- the longer and safer our lives become, the more we fear losing them- the more we stand to lose by being adventurous. So those ten year olds who are the safest human beings who’ve ever lived, aren’t allowed outdoors to play. And we chose to put the elderly into solitary confinement rather than risk them dying of covid.

[@lostieaddict]

Well said.

[@sharonvass8700]

@@lostieaddict good point.

[@sharonvass8700]

The Covid lock down was just hysteria comes from watching dramas like the walking dead.there is a saying in the bible in life we are in death can't have one with out the other .Let's live and stop worrying how about making people's lives better by r

[@cherylpa527]

@@sharonvass8700 why even watch this video then? Your bible has your answers. Not mine.

[@jewel2022now]

Yrs, so true

[@ianwishartsinclair8044]

A treatment ?....What of a healthy diet and a supportive ,loving community . Those areas of the world where a ' happy' lifestyle leads to long life . Not a 'drug'

[@peterlearner8594]

With longer life scientists can continue their work longer. A genius that lives longer can contribute more to science

[@Len124]

Maybe this says more about me than the topic, but when discussing anti-aging technology, my mind inevitably turns to the tragedy of the last generation to age. What a horrible fate: doomed to age because you _just_ missed the cutoff, after which no one need die again.

[@danamather3669]

I thought about that too, mostly because I am likely to be very close to that cutoff date. It's like being the guy who got killed on the last day of the war.

[@Wasteomindy]

And what if this last dying generation turns out to be ours :D

[@aafsariqbal6353]

@@Wasteomindy it will never and stopping ageing is impossible all cells of your body slowly die all of them

[@vhawk1951kl]

I have to say that at 70 plus plus and increasing by the second, the prospect of not dying or landing fills me with absolute horror, as it does my friends in their 90s and they and I don't expect to continue or be forced to continue for long, and all of us agree that it is a *kindness* that we are allowed to land or die. We also all agree that it is as futile as it is asinine to be frightened of what being frightened cannot possibly alter which for all we know may be perfectly pleasant. It is a *kindness* to men (human beings) that they can die - must *inescapably and inevitably* die, or hit the ground high-speed having commenced the process of falling by being born or first drawing breath.

[@ren1132]

And being vaccinated and injured, how does that affect the body?

[@diantonovich]

I am pretty excited about this! It motivates me to invest in my and my children's education

[@robertwatson3962]

Here is my belief system: "I am ageless, acquiring perfect health!" No such thing as perfect health, but that shouldn't stop you from working towards it. Everything is possible even the impossible if you change how you relate to it. Besides, if you are so busy working on your health you won't think about your age the same way. RJW

[@dogfriendly1623]

The thought of staying young is appealing but I'm not so sure about extended life if everyone I know and love has gone

[@SirTenenbaum]

Fascinating presentation and topic! I fully intend to read his book.

[@yankee2666]

There’s a great little book on natural healing written by an older man who cured himself of a number of maladies without medical intervention, called My Physician, Myself. I read it a couple of years ago but lost my copy. I’m going to Amazon right now to order one and be more careful with it. It’s more than worth the read. You might look into the work of Luigi Cornaro, a Venetian nobleman who lived to be 102.

[@nicksutton2964]

I believe that 40 years from now, Andrew Steele will still look and sound exactly the same as he does today.

[@DistinctiveBlend]

If you believe that I have a bridge to sell you

[@defaultdefault812]

I have some Dutch tulips to sell you.

[@vhawk1951kl]

the only thing I can say to that is that there is another one born every minute

[@deborahdean8867]

That's what the delusional western culture lazily indulges in , inability to access reality.

[@tensevo]

It would have been interesting to investigate known long lived populations, such as Ikarian, mediterranean, etc, and the diet, lifestyle they adopt, plus religion adds 10 years to life, perhaps fasting, and strict diets.....? also the human interaction and community in a non-work related environment.

[@Womble1252]

Very good comment.. you are on the money with your comment..

[@LilyGazou]

The monetary profit is in drugs.

[@paulinedavies4077]

From this, whilst very interesting, it seems to me that the aim of elongating ones life means some scientists are also tasked with increasing the huge profits of the pharmaceutical industry.. Eat healthily, exercise if it's only walking, retain a sense of humour, be kind to others, and live what life you have to the best.

[@jbaker7134]

Psalm 90:10 The days of our years are threescore years and ten; and if by reason of strength they be fourscore years, yet is their strength labour and sorrow; for it is soon cut off, and we fly away.

[@fuzzycounsellor9147]

Amen

[@martinsnell253]

I love boffins who can make complex subjects accessible to duffers like me! On the ethical question (ie with reference to the global warming issue) there is strong evidence to suggest that birthrates decline with increased life expectancy - particularly where that life expectancy is accompanied by improved health outcomes in later years. The fear of growing old alone, with no support system and no social support network often drives the perceived necessity for larger families. The thought that we might be able and capable in later life is, I would imagine likely to reverse that trend.

[@conniemay23]

An excellent presentationa and presenter. Eye-opening information on aging and mortality.

[@carollen5633]

Reality. Where will we get money for living longer? Is that new discovery only affordable for the elites? In this case they will run out of servants and slaves. Sorry to say.

[@theon9575]

Very interesting, indeed. A superb lecture. Thank you. As a PhD medical scientist myself, I think my rate of learning from you was high, but no-where near your rate of utterance. You did not refer, however, to the personal & social psychological aspects and implications. We may not like the idea of ageing and dying, but the idea of NOT ever dying seems even worse from a number of perspectives. My own thoughts about these personal, psychosocial implcations started when I first saw Leoš Janáček's opera, "The Macropoulos Affair", in which Emelia's life becomes almost unbearable. I recommend it.

[@binathere2574]

300 years would become tedious.

[@WesFitz420]

I’d much rather never die

[@GypsyDove]

I don't think most truly ever contemplate past that desire they have to live forever. I'm not aware of the opera you mentioned. If one ponders in a balanced perspective of pros an cons not just pros I think would affect one's perspective.

[@davidmccaig6647]

@@WesFitz420 Unfortunately not dying from biological processes guarantees that you will die from accidental means. Live long enough and you will die eventually.

[@gplunk]

I would highly suggest playing this back at 3/4 speed (.75); to give you any kind of chance at keeping pace w/ the presenter's speech pattern....

[@dr.samierasadoonalhassani2669]

Thanks ,listening again,the rapid speed of the speech is really counterproductive,needs improvement to enjoy the topic,words coming like bullets and not in soft relaxed way.

[@jps-ib8vh]

Excellent talk. However I missed the well known fact that reducing metabolism (eating less) is proved to slow down the aging process. Probably it is the same mechanism as taking Metformin

[@nHans]

Go ahead and watch the Q&A-the link is in the description. Somebody asks that question and he answers it in some detail.

[@victorycall]

Thanks for bringing up the point that it may be prudent to strive to slow down our metabolism. The weight loss arena usually emphasizes speeding up the metabolism, to lose weight (and by extension, to be able to eat more without putting on weight). Techniques for speeding up the metabolism include taking stimulants, exogenous hormones, and extreme physical activity. All that is surely bad for longevity.

[@Grizabeebles]

Neurons have been observed retracting dendrites and reducing surface area when a subject is fasting. This is potential empirical evidence that lowering metabolism may extend life-span but may also impair memory formation and recall - thus "making you dumber" in a colloquial sense. It's kinda neat how cognitive productivity really balances out longetivity.

[@wheathusk2499]

Meditation also reduces metabolism. I was doing a lot of it few years ago and my metabolism was at an all time low. When you go into deeper states you take less breaths. In our culture they say the number of breaths you take are counted so if it slows down your breathing so much you may live longer. This is why some yogis in Meditation live more than 100 years easily but most of that time is spent inwards.

[@ohitsjustsomeguy4156]

Yes but that effect is quite small in relation to the other topics but yes its likley the same mechanism as with metformin which would be activation of the AMPK pathway.

[@bernadettefern]

Maturing through the years that we live (regardless of how many) does not inevitably mean we will develop chronic or degenerating conditions. Our potential and our foundation of strengths and weaknesses are genetic. However, acquired conditions can also be determined by habitual, lifelong actions whether one gets “old” in the sense of deterioration or cleanses and renews through what we consume, what situations we have in our environment, in addition to any type of traumatic influence. It is best to communicate by using word correctly and precisely.

[@notbuyingit2204]

Parasite infections are the cause of most serious diseases.

[@ednichol7419]

ignoring for the moment overwhelming disease, ask what causes a cell to fail in operation.

[@SherryEllesson]

My favorite subject! and the one I spent years on, writing my own book Young For Your Own Good. I'm surprised Dr Steele didn't address Epigenetics, which of course has a huge effect on the cells' ageing process, nor did he mention mTor, which also may be addressed in some of the other categories of research in his list that his admittedly short talk had time for. I hope everyone's also following Dr David Sinclair and his book Lifespan and his work at Harvard.

[@JullianLue]

Where is this book?

[@SherryEllesson]

@@JullianLue If you're asking about my book, it's on Amazon and is also available from my publisher, Balboa Press.

[@examplerkey]

He said he almost did a Ph.D. If he had done so, he would have learned the things you mentioned!

[@thegreaterconundrum]

Dr. David Sinclair has been under some scrutiny as of late, hasn't he? I'm not sure he is the most reliable place to start with this stuff. Last I heard he is being sponsored by a lot of corporate funded clinical trials and supplement companies.

[@jspohl]

Decline is completely optional - and not inevitable. There’s more and more examples around us that prove it. ✨

[@luismiguelmartinezsanchez4069]

si pero la gente no lo entiende dice que el declive es inevitable

[@debasishborthakur2141]

Aging is the most disgusting problem we humans face..